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Jian-Xin Zhou

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https://www.readbyqxmd.com/read/28827477/trimester-specific-weight-gain-and-midpregnancy-diastolic-blood-pressure-rebound-during-normotensive-pregnancy
#1
Qiong Lei, Xin Zhou, Dong-Mei Duan, Li-Juan Lv, Xiao-Hong Lin, Wen-Jie Ji, Wei Cai, Zhuoli Zhang, Yu-Ming Li, Jian-Min Niu
The longitudinal exposure-response relationship between trimester-specific gestational weight gain (GWG) and blood pressure (BP) during pregnancy is not well understood. We retrospectively assessed 1112 uncomplicated, normotensive pregnant women whose body weight and BP were measured from 12(+0) to 40(+0) weeks of gestation from a hospital-based cohort. By using growth curve modeling, a J-shaped pattern dominated diastolic BP (DBP) changing dynamics, with a midpregnancy drop at 20(+0) to 22(+0) weeks followed by a rebound...
August 21, 2017: Hypertension
https://www.readbyqxmd.com/read/28819375/bone-marrow-derived-mesenchymal-stem-cells-involve-in-the-lymphangiogenesis-of-lung-cancer-and-jinfukang-inhibits-the-involvement-in-vivo
#2
Xian-Mei Zhou, Dan Wang, Hai-Lang He, Jie Tang, Jing Wu, Ling Xu, Jian-Xin Li
Lymphangiogenesis plays an important role in cancer metastasis. Bone marrow-derived mesenchymal stem cells (BMMSCs) migrate to the site of tumorigenesis and in turn promote the metastasis. However, whether BMMSCs involve in the lymphangiogenesis of lung cancer is unclear. Jinfukang has clinically been used for the treatment of non small cell lung cancer (NSCLC) in China. In this study, to investigate the involvement of BMMSCs in lymphangiogenesis in lung cancer, and evaluate the inhibitory effect of Jinfukang on the lymphangiogenesis, chimeric mice were prepared by transplanting bone marrow from green fluorescent protein (GFP) transgenic mice (C57BL/6-EGFP) into irradiated C57BL/6 mice...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28815252/-expression-of-ptprz1-in-oral-squamous-cell-carcinoma-originated-from-oral-submucous-fibrosis-and-its-clinical-significance
#3
Rong Zhu, Xin-Chun Jian, De-Yu Liu, Chao Zhou, Yuan Wang
PURPOSE: This study was aimed to detect the expression of PTPRZ1 in oral squamous cell carcinoma (OSCC) originated from oral submucous fibrosis (OSF), and discuss its role in the development and progression of OSCC originating from OSF as well as its clinical significance. METHODS: Immunohistochemisty (IHC) and Western blot (WB) for the expression and distribution of PTPRZ1 were carried out in 36 cases of OSF transforming into OSCC, 23 cases of OSCC and 21 cases of healthy controls...
April 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28815250/-methods-and-effects-of-injection-of-salvianolic-acid-b-combined-with-triamcinolone-acetonide-in-the-treatment-of-oral-submucous-fibrosis
#4
Yi-Cai Xiao, Xin-Chun Jian, Lian Zheng, Chao Zhou, Yong-Xiu DU
PURPOSE: To introduce the methods of triamcinolone acetonide (TA) and salvianolic acid B(SA-B) intralesional injection in the treatment of oral submucous fibrosis and evaluate the treatment effects. METHODS: TA combined with SA-B were consecutively applied intralesionally 1 time weekly for 30 times. The technique of intralesional injection was that syringe needle be emptied into submucous tissues 1 cm posterior to the corner of oral cavity running from the front to retromolar area by pushing the injection, then the syringe needle retained to the original point and upward from the front to retromolar area by pushing the injection, finally the syringe needle returned to the starting point and downward from the front to retromolar area by pushing the injection...
April 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28811187/chiral-resolution-absolute-configuration-and-bioactivity-of-a-new-racemic-asarone-derivative-from-the-rhizome-of-acorus-tatarinowii
#5
En Gao, Fei-Fei Ren, Jian Zou, Yang Yu, Hong-Xia Fan, Zheng-Qun Zhou, Guo-Dong Chen, Rong-Rong He, Xin-Sheng Yao, Hao Gao
A new asarone-derived racemate (1) was isolated from the rhizome of Acorus tatarinowii. The structure of 1 was established by comprehensive spectroscopic analyses, and it was successfully resolved by chiral HPLC, demonstrating that it is racemic. The absolute configurations of 1a [(-)-acortatarone A] and 1b [(+)-acortatarone A] were determined using quantum chemical calculations. Compounds 1a and 1b were the first cases of asarone derivatives with the 5,7-dialkyl-6-aryl-8-oxabicyclo[3.2.1]oct-3-en-2-one core...
August 12, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28810614/evolution-of-correlation-between-helicobacter-pylori-infection-and-autoimmune-liver-disease
#6
Xin-Guo Peng, Yu-Yuan Li, Hui-Ting Chen, Yan Zhou, Jian-Guo Ma, Hong-Min Yin
The present study was planned to evaluate correlation between Helicobacter pylori (HP) infection and autoimmune liver disease (AILD). A total of 60 patients diagnosed with AILD in Affiliated Hospital of Binzhou Medical College were continuously enrolled in the present study. HP infection was detected by 13C-urea breath test. The levels of anti-myeloperoxidase were tested by ELISA. The positive rate of anti-nuclear antibody (ANA), anti-mitochondrial antibody (AMA), anti-smooth muscle antibody (SMA) and anti-neutrophil cytoplasm antibody (ANCA) were tested by indirect immunofluorescence...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28803429/patients-with-primary-breast-and-primary-female-genital-tract-diffuse-large-b-cell-lymphoma-have-a-high-frequency-of-myd88-and-cd79b-mutations
#7
Xin-Xin Cao, Jian Li, Hao Cai, Wei Zhang, Ming-Hui Duan, Dao-Bin Zhou
This study is to retrospectively evaluate the prevalence of MYD88 and CD79B mutations and the clinicopathologic characteristics of patients with primary diffuse large B cell lymphoma (DLBCL) of the female genital tract and breast. The characteristics, treatments, and outcomes of 19 patients diagnosed with primary DLBCL of the female genital tract and breast, who had formalin-fixed and paraffin-embedded tissues obtained from diagnostic samples diagnosed between January 2004 and June 2016, were analyzed retrospectively...
August 12, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/28800528/comparison-of-three-officinal-species-of-callicarpa-based-on-a-biochemome-profiling-strategy-with-uhplc-it-ms-and-chemometrics-analysis
#8
Meng-Lu Chen, Wen-Qi Chang, Jian-Liang Zhou, Ying-Hao Yin, Wen-Rui Xia, Jian-Qun Liu, Li-Fang Liu, Gui-Zhong Xin
Traditional Chinese medicine (TCM) materials with closely related species are frequently fungible in clinical use. Therefore, holistic comparison of the composition in bioactive compounds is essential to evaluate whether they are equivalent in efficacy. Taking three officinal species of Callicarpa as a case, we proposed and validated a standardized strategy for the discrimination of closely related TCM materials, which focused on the extraction, profiling and multivariate statistical analysis of their biochemome...
August 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28783909/an-underappreciated-hotspot-of-antibiotic-resistance-the-groundwater-near-the-municipal-solid-waste-landfill
#9
Qing-Lin Chen, Hu Li, Xin-Yuan Zhou, Yi Zhao, Jian-Qiang Su, Xian Zhang, Fu-Yi Huang
Landfills are so far the most common practice for the disposals of municipal solid waste (MSW) worldwide. Since MSW landfill receives miscellaneous wastes, including unused/expired antibiotics and bioactive wastes, it gradually becomes a huge potential bioreactor for breeding antibiotic resistance. Antibiotic resistance genes (ARGs) in landfill can flow to the environment through leakage of landfill leachate and pose a risk to public health. Using high throughput quantitative Polymerase Chain Reaction (HT-qPCR), we investigated the prevalence, diversity of ARGs and its association with various mobile genetic elements (MGEs) in MSW landfill groundwater...
July 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28776553/application-of-keyhole-microneurosurgery-in-china
#10
Li-Gang Chen, Shu-Da Chen, Guang-Fu Huang, Ying Huang, De-Zhi Kang, Qing Lan, Gang Li, Xin-Gang Li, Zhi-Xiong Liu, Song-Tao Qi, Xin-Hua Tian, Guo-Liang Wang, Shuo Wang, Xiang-Yu Wang, Yong-Fei Wang, Yun-Jie Wang, Chao You, Yan-Bing Yu, Shu-Yuan Yue, Dong Zhang, Jian-Min Zhang, Jian-Ning Zhang, Jun-Ting Zhang, Shi-Zhong Zhang, Xian Zhang, Ya-Zhuo Zhang, Ji-Zong Zhao, Wei-Guo Zhao, Yuan-Li Zhao, Ding-Biao Zhou, Liang-Fu Zhou
No abstract text is available yet for this article.
August 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28776539/characteristics-management-and-outcomes-of-acute-heart-failure-in-the-emergency-department-a-multicenter-registry-study-with-1-year-follow-up-in-a-chinese-cohort-in-beijing
#11
Guo-Gan Wang, Si-Jia Wang, Jian Qin, Chun-Sheng Li, Xue-Zhong Yu, Hong Shen, Li-Pei Yang, Yan Fu, Ya-An Zheng, Bin Zhao, Dong-Min Yu, Fu-Jun Qin, De-Gui Zhou, Ying Li, Fu-Jun Liu, Wei Li, Wei Zhao, Xin Gao, Zheng Wang, Ming Jin, Hong Zeng, Yi Li, Guo-Xing Wang, Hong Zhou, Xiao-Lu Sun, Peng-Bo Wang, Kam-Sang Woo
BACKGROUND: The emergency department (ED) has a pivotal influence on the management of acute heart failure (AHF), but data concerning current ED management are scarce. This Beijing AHF Registry Study investigated the characteristics, ED management, and short- and long-term clinical outcomes of AHF. METHODS: This prospective, multicenter, observational study consecutively enrolled 3335 AHF patients who visited 14 EDs in Beijing from January 1, 2011, to September 23, 2012...
August 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28775282/ecological-effect-of-arginine-on-oral-microbiota
#12
Xin Zheng, Jinzhi He, Lin Wang, Shuangshuang Zhou, Xian Peng, Shi Huang, Liwei Zheng, Lei Cheng, Yuqing Hao, Jiyao Li, Jian Xu, Xin Xu, Xuedong Zhou
Dental caries is closely associated with the microbial dybiosis between acidogenic/aciduric pathogens and alkali-generating commensal bacteria colonized in the oral cavity. Our recent studies have shown that arginine may represent a promising anti-caries agent by modulating microbial composition in an in vitro consortium. However, the effect of arginine on the oral microbiota has yet to be comprehensively delineated in either clinical cohort or in vitro biofilm models that better represent the microbial diversity of oral cavity...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28772842/a-study-of-efficiency-droop-phenomenon-in-gan-based-laser-diodes-before-lasing
#13
Mei-Xin Feng, Qian Sun, Jian-Ping Liu, Zeng-Cheng Li, Yu Zhou, Shu-Ming Zhang, Hui Yang
Carrier recombination behavior in c-plane GaN-based laser diodes (LDs) is numerically investigated by using the commercial software LASTIP. It is found that efficiency droop phenomenon does exist in GaN-based LDs before lasing, which is confirmed by experimental results. However, the current density corresponding to the peak efficiency of GaN-based LDs before lasing, Jmax, is nearly 40 A/cm², which is much lower than that reported by other studies. The reported Jmax, measured from the cavity facet side is modulated by the absorption of quantum wells, which shifts the Jmax to a higher value...
April 30, 2017: Materials
https://www.readbyqxmd.com/read/28771580/glipr1-modulates-the-response-of-cisplatin-resistant-human-lung-cancer-cells-to-cisplatin
#14
Xin Gong, Jing Liu, Dan Zhang, Dawei Yang, Zhihui Min, Xiaoxing Wen, Guifang Wang, Huayin Li, Yuanlin Song, Chunxue Bai, Jing Li, Jian Zhou
BACKGROUND AND OBJECTIVE: Chemotherapy drugs, such as cisplatin (DDP), improve the survival of patients with lung cancer by inducing apoptosis in cancer cells, which quickly develop resistance to DDP through uncharacterized mechanisms. Glioma Pathogenesis-Related Protein 1 (GLIPR1) plays an important role in cell proliferation, migration and apoptosis. However, the expression and function of GLIPR1 in mediating DDP resistance in human lung adenocarcinoma A549/DDP and human large cell lung cancer H460/DDP cells has not yet been reported...
2017: PloS One
https://www.readbyqxmd.com/read/28770541/optimal-esophageal-balloon-volume-for-accurate-estimation-of-pleural-pressure-at-end-expiration-and-end-inspiration-an-in-vitro-bench-experiment
#15
Yan-Lin Yang, Xuan He, Xiu-Mei Sun, Han Chen, Zhong-Hua Shi, Ming Xu, Guang-Qiang Chen, Jian-Xin Zhou
BACKGROUND: Esophageal pressure, used as a surrogate for pleural pressure, is commonly measured by air-filled balloon, and the accuracy of measurement depends on the proper balloon volume. It has been found that larger filling volume is required at higher surrounding pressure. In the present study, we determined the balloon pressure-volume relationship in a bench model simulating the pleural cavity during controlled ventilation. The aim was to confirm whether an optimal balloon volume range existed that could provide accurate measurement at both end-expiration and end-inspiration...
December 2017: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/28767395/prohibitin-relocated-to-the-front-ends-can-control-the-migration-directionality-of-colorectal-cancer-cells
#16
Li-Li Ma, Lan Shen, Gui-Hui Tong, Na Tang, Yang Luo, Li-Li Guo, Chun-Ting Hu, Ying-Xin Huang, Guan Huang, Fang-Yan Jing, Chao Liu, Zhuo-Yi Li, Na Zhou, Qian-Wen Yan, Yan Lei, Shi-Jie Zhu, Zhi-Qiang Cheng, Guang-Wen Cao, Yong-Jian Deng, Yan-Qing Ding
Directional migration is a cost-effective movement allowing invasion and metastatic spread of cancer cells. Although migration related to cytoskeletal assembly and microenvironmental chemotaxis has been elucidated, little is known about interaction between extracellular and intracellular molecules for controlling the migrational directionality. A polarized expression of prohibitin (PHB) in the front ends of CRC cells favors metastasis and is correlated with poor prognosis for 545 CRC patients. A high level of vascular endothelial growth factor (VEGF) in the interstitial tissue of CRC patients is associated with metastasis...
July 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28752641/influenza-virus-like-particles-harboring-h9n2-ha-and-na-proteins-induce-a-protective-immune-response-in-chicken
#17
Xin Li, Houbin Ju, Jian Liu, Dequan Yang, Xinyong Qi, Xianchao Yang, Yafeng Qiu, Jie Zheng, Feifei Ge, Jinping Zhou
BACKGROUND: Avian influenza viruses represent a growing threat of an influenza pandemic. The co-circulation of multiple H9N2 genotypes over the past decade has been replaced by one predominant genotype-G57 genotype, which displays a changed antigenicity and improved adaptability in chickens. Effective H9N2 subtype avian influenza virus vaccines for poultry are urgently needed. OBJECTIVE: In this study, we constructed H9N2 subtype avian influenza virus-like particle (VLP) and evaluated its protective efficacy in specific pathogen-free (SPF) chickens to lay the foundation for developing an effective vaccine against influenza viruses...
July 28, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28748976/syntheses-structures-and-magnetic-properties-of-the-lanthanide-complexes-of-the-pyrimidyl-substituted-nitronyl-nitroxide-radical
#18
Jian Wang, Hao Miao, Zhao-Xin Xiao, Yan Zhou, Lin-Dan Deng, Yi-Quan Zhang, Xin-Yi Wang
Four 2p-4f Ln(III)-radical complexes, [(NIT-2-Pm)Ln(hfac)3]·0.5C7H16 (NIT-2-Pm = 2-pyrimidyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-oxy-3-oxide, hfac = hexafluoroacetylacetonato, Ln = Tb (1), Dy (2), Ho (3) and Er (4)), and four 4f-2p-4f Ln(III)-radical-Ln(III) complexes, [(μ-NIT-2-Pm)Ln2(hfac)6(H2O)2]·0.5C7H16 (Ln = Tb (5), Dy (6), Ho (7) and Er (8)) have been synthesized and characterized structurally and magnetically. These compounds can be selectively obtained by controlling the reaction ratio of Ln(hfac)3·2H2O to the radical ligand NIT-2-Pm...
July 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28736104/opioid-induced-constipation-relief-of-fixed-ratio-combination-prolonged-release-oxycodone-naloxone-compared-with-oxycodone-and-morphine-for-chronic-non-malignant-pain-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
REVIEW
Lang Huang, Jian-Guo Zhou, Yu Zhang, Fei Wang, Yi Wang, Da-Hai Liu, Xin-Juan Li, Shui-Ping Lv, Su-Han Jin, Yu-Ju Bai, Hu Ma
BACKGROUND: Opioid-induced constipation (OIC) is one of the most frequent and severe adverse events (AEs) following treatment with opioids. Recent studies have indicated that fixed-ratio combination prolonged-release oxycodone/naloxone (OXN PR) could decrease OIC with similar pain relief compared with other opioids. OBJECTIVES: We systematically reviewed (PROSPERO registration numbers: CRD42016036244) the constipation relief of OXN PR compared with other opioids regardless of formulation, prolonged-release or extended-release used for the relief of chronic pain...
July 20, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28732877/enhanced-antitumor-activity-of-gemcitabine-by-polysaccharide-induced-nk-cell-activation-and-immune-cytotoxicity-reduction-in-vitro-vivo
#20
Xin Xie, Yiran Zhou, Xue Wang, Jian Guo, Jingwen Li, Hongye Fan, Jie Dou, Baiyong Shen, Changlin Zhou
The polysaccharide SEP has been reported to activate NK and T cells via TLR2/4. Here, the combination of gemcitabine (GEM) and SEP against HepG-2 was investigated. SEP apparently enhanced antitumor activity of gemcitabine against liver cancer through stimulating NKG2D and DAP10/Akt pathway to activate NK cells. The NKG2D upregulation could improve the sensitivity of NK-92 cells targeting to its ligand MICA expressed on HepG-2 cells. Meanwhile, GEM up-regulated MICA expression and attenuated soluble MICA secretion through inhibiting ADAM10 expression, which in turn enhanced the cytotoxicity of NK-92 cells against cancer cells...
October 1, 2017: Carbohydrate Polymers
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