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https://www.readbyqxmd.com/read/28231664/-cross-sectional-surveys-on-the-use-of-recreational-drug-nitrous-acid-ester-rush-poppers-in-men-who-have-sex-with-men-nanjing
#1
Z P Zhu, M Zhang, Y Y Xu, W J Xu, L Liu, S S Wu, L Guo, X Li
Objective: To investigate the situation of recreational drug nitrous acid ester inhaler-rush poppers use in men who have sex with men (MSM). Methods: From April to June in 2014, October to December in 2014, April to June in 2015, three round cross-sectional surveys were conducted in MSM recruited in Nanjing by means of serum test and questionnaire survey. Results: Of the 1 721 MSM surveyed in three round, 19.3% (332/1 721) had ever used rush poppers, the proportions of MSM who used rush poppers in three round surveys showed an increasing trend (liner by liner χ(2)= 14...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231663/-factors-associated-with-lost-of-follow-up-of-men-who-have-sex-with-men-in-a-gay-bathhouse-cohort-study-in-tianjin-2012-2015
#2
Y Guo, N Zhou, J Yang, P Xu, H Gong, M H Yu
Objective: To understand the rate of follow-up lost in men who have sex with men (MSM) in a gay bathhouse cohort study in Tianjin and the associated factors. Methods: The open cohort study in gay bathhouse was launched in 2012 in Tianjin, and the MSM for baseline survey were recruited from January to June 2012, while the follow up was carried out every six months. A questionnaire survey and HIV test were conducted in the study. The MSM who were HIV negative in the baseline survey in 2012 were used for follow up lost analysis...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28230311/prevalence-of-and-factors-associated-with-unprotected-anal-intercourse-with-regular-and-nonregular-male-sexual-partners-among-newly-diagnosed-hiv-positive-men-who-have-sex-with-men-in-china
#3
Z Wang, X Wu, Jtf Lau, Pkh Mo, Wws Mak, X Wang, X Yang, D Gross, H Jiang
OBJECTIVES: This study investigated the prevalence of, and multi-dimensional factors associated with, unprotected anal intercourse (UAI) with regular male sexual partners ('regular partners') and nonregular male sexual partners ('nonregular partners') among newly diagnosed HIV-positive men who have sex with men (MSM) in Chengdu, China. METHODS: A total of 225 newly diagnosed HIV-positive MSM were interviewed using a combined interviewer-computer-assisted method in Chengdu, China...
February 23, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28229612/preliminary-results-of-a-screening-program-for-anal-cancer-and-its-precursors-for-hiv-infected-men-who-have-sex-with-men-in-vigo-spain
#4
Mauricio Iribarren Díaz, Antonio Ocampo Hermida, Joaquín González-Carreró Fojón, Rebeca Longueira Suárez, Alberto Rivera Gallego, Enrique Casal Núñez, Antón Ocampo Álvarez, Edward Cachay
BACKGROUND: Men who have sex with men (MSM) infected with human immunodeficiency virus (HIV) have the highest risk of developing anal cancer (AC). The objective of this study was to describe our screening implementation program in this population, and report the prevalence of human papillomavirus (HPV) anal infection, and cytological and histological findings in a Spanish medium-size community (Vigo, Spain). METHOD: Prospective cohort analysis of 240 HIV-infected MSM...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28225608/time-dependent-markov-state-models-for-single-molecule-force-spectroscopy
#5
Susmita Ghosh, Abhijit Chatterjee, Swati Bhattacharya
This Letter demonstrates that using time-dependent Markov state models (TD-MSMs) one can obtain molecular-scale insights into force-extension curves for a variety of stretching experiments. A master-MSM constructed at a reference extension using a handful of molecular dynamics calculations forms the basis for generating the required TD-MSM. Changes in the network topology upon stretching is related through a thermodynamic quantity termed the mechanical disposition. Proof-of-principle is provided using a stretched alanine decapeptide under a time-varying pulling force...
February 22, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28224313/sexual-stereotypes-ascribed-to-black-men-who-have-sex-with-men-an-intersectional-analysis
#6
Sarah K Calabrese, Valerie A Earnshaw, Manya Magnus, Nathan B Hansen, Douglas S Krakower, Kristen Underhill, Kenneth H Mayer, Trace S Kershaw, Joseph R Betancourt, John F Dovidio
Sexual stereotypes may adversely affect the health of Black men who have sex with men (MSM). Greater understanding of the nature and nuances of these stereotypes is needed. This online, survey-based study used an inductive, intersectional approach to characterize the sexual stereotypes ascribed to Black MSM by the U.S. general public, their distinctiveness from those ascribed to Black men and MSM in general, and their relative prototypicality as compared to dominant subgroups. Members of the public, recruited in 2014-2015, were randomly assigned to survey conditions that varied systematically by race (Black, White, or unspecified) and sexual orientation (gay, heterosexual, or unspecified) of a designated social group...
February 21, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28222757/spatiotemporal-dynamics-of-hiv-1-transmission-in-france-1999-2014-and-impact-of-targeted-prevention-strategies
#7
Antoine Chaillon, Asma Essat, Pierre Frange, Davey M Smith, Constance Delaugerre, Francis Barin, Jade Ghosn, Gilles Pialoux, Olivier Robineau, Christine Rouzioux, Cécile Goujard, Laurence Meyer, Marie-Laure Chaix
BACKGROUND: Characterizing HIV-1 transmission networks can be important in understanding the evolutionary patterns and geospatial spread of the epidemic. We reconstructed the broad molecular epidemiology of HIV from individuals with primary HIV-1 infection (PHI) enrolled in France in the ANRS PRIMO C06 cohort over 15 years. RESULTS: Sociodemographic, geographic, clinical, biological and pol sequence data from 1356 patients were collected between 1999 and 2014. Network analysis was performed to infer genetic relationships, i...
February 21, 2017: Retrovirology
https://www.readbyqxmd.com/read/28222118/social-structural-behavioral-and-clinical-factors-influencing-retention-in-pre-exposure-prophylaxis-prep-care-in-mississippi
#8
Trisha Arnold, Lauren Brinkley-Rubinstein, Philip A Chan, Amaya Perez-Brumer, Estefany S Bologna, Laura Beauchamps, Kendra Johnson, Leandro Mena, Amy Nunn
Pre-exposure prophylaxis (PrEP) is a biomedical intervention that can reduce rates of HIV transmission when taken once daily by HIV-negative individuals. Little is understood about PrEP uptake and retention in care among the populations most heavily impacted by the HIV epidemic, particularly among young men who have sex with men (YMSM) in the Deep South. Therefore, this study explored the structural, social, behavioral, and clinical factors that affect PrEP use and retention in care among YMSM in Jackson, Mississippi...
2017: PloS One
https://www.readbyqxmd.com/read/28220321/a-snapshot-of-chlamydia-trachomatis-genetic-diversity-using-multilocus-sequence-type-analysis-in-an-australian-metropolitan-setting
#9
J A Danielewski, S Phillips, F Y S Kong, K S Smith, J S Hocking, R Guy, C K Fairley, S M Garland, S N Tabrizi
High-resolution screening methodologies which enable the differentiation of Chlamydia trachomatis at the strain level, directly from clinical samples, can provide the detailed information required for epidemiological questions such as the dynamics of treatment failure. In addition, they give a detailed snapshot of circulating C. trachomatis genetic variation, data which are currently lacking for the Australian population. In the context of two Australian clinical trials, we assessed the genetic diversity of C...
February 20, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28220310/network-centrality-and-geographical-concentration-of-social-and-service-venues-that-serve-young-men-who-have-sex-with-men
#10
Kayo Fujimoto, Rolf Turner, Lisa M Kuhns, Ju Yeong Kim, Jing Zhao, John A Schneider
This study examines network centrality of inter-venue networks formed by collaboration, competition, and sponsorship relationships among venues that serve young men who have sex with men (MSM) aged 16-29 years in relation to their geographical concentrations in Chicago, Illinois, and Houston, Texas. Our data on the physical venues comprised 116 venues in Chicago and 102 venues in Houston. We examined the relationship between the network centrality of different relations and the geographical intensity among these venues, and considered neighborhood-level socioeconomic determinants of health...
February 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28215536/gel-gel-phase-separation-within-milk-sphingomyelin-domains-revealed-at-the-nanoscale-using-atomic-force-microscopy
#11
Fanny Guyomarc'h, Maohui Chen, Oumaima Et-Thakafy, Shan Zou, Christelle Lopez
The milk sphingomyelin (MSM) is involved in the formation of ordered lipid domains in the biological milk fat globule membrane (MFGM), where it accounts for about 30% of the polar lipids. Moreover, MSM exhibits a large variety in saturated acyl chain lengths (from C16:0 to C24:0-SM) compared to other natural sphingomyelins, which may impact the packing of MSM molecular species in the gel phase domains and the topography of the MFGM. To investigate this, supported lipid bilayers of synthetic sphingomyelins or of MSM-containing mixtures, including a MFGM polar lipid extract, were imaged at temperatures below the Tm of MSM (i...
February 16, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28207363/structural-concerns-for-msm-health-in-revising-the-precautionary-principle
#12
Barry DeCoster
No abstract text is available yet for this article.
March 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28202924/reevaluating-canada-s-policy-for-blood-donations-from-men-who-have-sex-with-men-msm
#13
Bellal Jubran, Maxime Billick, Gabriel Devlin, Jeremy Cygler, Bertrand Lebouché
During the HIV/AIDS epidemic of the 1980s, most of the developed world instituted a permanent ban on blood donations from men who have sex with men (MSM). In recent years, public health agencies across Europe and North America are reconsidering and rescinding these restrictions. We examine the Canadian climate, where MSM may donate blood only after a 5-year deferral period. We review circumstances of the initial ban on MSM blood donations and recent social, legal, and economic changes that have encouraged Canadian public health officials to consider policy reform...
December 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28202736/hiv-and-sti-s-among-men-who-have-sex-with-men-in-dodoma-municipality-tanzania-a-cross-sectional-study
#14
Elia John Mmbaga, Kåre Moen, Neema Makyao, Rose Mpembeni, Melkizedeck T Leshabari
OBJECTIVES: To determine the seroprevalence of HIV, STI and related risks among men who have sex with men (MSM) in Dodoma municipality, Tanzania. METHODS: A cross-sectional study using respondent-driven sampling was employed to recruit study participants aged 18 years and above. Data on sociodemographics, HIV/STI knowledge and sexual practices were collected. Blood samples were tested for HIV and selected STIs. RESULTS: A total of 409 participants aged from 18 to 60 years took part in this study...
February 15, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28197984/quantifying-bacterial-attachment-and-detachment-using-leaching-solutions-of-various-ionic-strengths-after-bacterial-pulse
#15
Nag-Choul Choi, Jae-Woo Choi, Kyu-Sang Kwon, Sang-Gil Lee, Soonjae Lee
In this study, we quantified the attachment and detachment of bacteria during transport in order to elucidate the contributions of reversible attachment on bacterial breakthrough curves. The first set of breakthrough experiment was performed for a laboratory sand column using leaching solutions of deionized water and mineral salt medium (MSM) of 200 mM with reference to KCl solution by employing Pseudomonas putida as a model bacterium. In the second set of experiment, the ionic strengths of leaching solutions immediately after bacterial pulse were lowered to tenfold and 100-fold diluted system (2 and 20 mM MSM) to focus on the influence of physicochemical factor...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28195781/an-evaluation-of-mpowerment-on-individual-level-hiv-risk-behavior-testing-and-psychosocial-factors-among-young-msm-of-color-the-monitoring-and-evaluation-of-mp-mem-project
#16
Gene Shelley, Weston Williams, Gary Uhl, Tamoka Hoyte, Adanze Eke, Carolyn Wright, Gregory Rebchook, Lance Pollack, Kelly Bell, Yan Wang, Qi Cheng, Susan M Kegeles
Young men who have sex with men (MSM) of color are at increased risk for HIV infection. Mpowerment (MP) is an intervention designed to reduce risky sexual behavior and increase HIV testing among young MSM ages 18-29. From 2009 to 2012, three community-based organizations with support from the U.S. Centers for Disease Control and Prevention evaluated MP among N = 298 participants. Following a repeated measures design, data from 3- and 6-month follow-ups were compared to baseline. HIV testing and self-efficacy for safer sex increased at both follow-up time points; self-acceptance as an MSM was higher at follow-up 2...
February 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28195777/hiv-prevention-opportunities-with-gps-based-social-and-sexual-networking-applications-for-men-who-have-sex-with-men
#17
Wendasha Jenkins Hall, Christina J Sun, Amanda E Tanner, Lilli Mann, Jason Stowers, Scott D Rhodes
The goal of this study was to gain insight on the sexual health needs of men who have sex with men (MSM) who use GPS-based social and sexual networking mobile applications (apps) and the future utility of app-based interventions. A health educator promoted HIV-testing resources in four popular apps used by MSM. Content analysis was used to identify salient themes that emerged from the conversations. Four major themes were identified: (1) soliciting sexual encounters, (2) relationship building, (3) HIV and STI-testing inquiries, and (4) seeking other sexual health information...
February 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28195201/crispr-cas9-mediated-genome-editing-in-wild-derived-mice-generation-of-tamed-wild-derived-strains-by-mutation-of-the-a-nonagouti-gene
#18
Michiko Hirose, Ayumi Hasegawa, Keiji Mochida, Shogo Matoba, Yuki Hatanaka, Kimiko Inoue, Tatsuhiko Goto, Hideki Kaneda, Ikuko Yamada, Tamio Furuse, Kuniya Abe, Yoshihisa Uenoyama, Hiroko Tsukamura, Shigeharu Wakana, Arata Honda, Atsuo Ogura
Wild-derived mice have contributed to experimental mouse genetics by virtue of their genetic diversity, which may help increase the chance of identifying novel modifier genes responsible for specific phenotypes and diseases. However, gene targeting using wild-derived mice has been unsuccessful because of the unavailability of stable embryonic stem cells. Here, we report that CRISPR/Cas9-mediated gene targeting can be applied to the Japanese wild-derived MSM/Ms strain (Mus musculus molossinus). We targeted the nonagouti (a) gene encoding the agouti protein that is localized in hair and the brain...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28193659/oligonucleotide-lipid-conjugates-forming-g-quadruplex-structures-are-potent-and-pangenotypic-hepatitis-c-virus-entry-inhibitors-in-vitro-and-ex-vivo
#19
George Koutsoudakis, Alexia Paris de León, Carolina Herrera, Marcus Dorner, Gemma Pérez-Vilaró, Sébastien Lyonnais, Santiago Grijalvo, Ramon Eritja, Andreas Meyerhans, Gilles Mirambeau, Juana Díez
An HCV epidemic affecting HIV-infected men who have sex with men (MSM) is expanding worldwide. Albeit the improved cure rates obtained with the new direct-acting antiviral drug (DAA) combinations, the high rate of reinfection within this population calls urgently for novel preventive interventions. Here we show in cell culture and ex vivo experiments with human colorectal tissue that lipoquads, G-quadruplex DNA structures fused to cholesterol, are efficient HCV pangenotypic entry and cell-to-cell transmission inhibitors...
February 13, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28192455/suicide-risk-in-a-representative-sample-of-people-receiving-hiv-care-time-to-target-most-at-risk-populations-anrs-vespa2-french-national-survey
#20
Maria Patrizia Carrieri, Fabienne Marcellin, Lisa Fressard, Marie Préau, Luis Sagaon-Teyssier, Marie Suzan-Monti, Valérie Guagliardo, Marion Mora, Perrine Roux, Rosemary Dray-Spira, Bruno Spire
BACKGROUND: Suicide risk is high among people living with HIV (PLHIV). This study aimed to identify major correlates of suicide risk in a representative sample of PLHIV in France, in order to help target individuals who would benefit from suicide risk screening and psychiatric care. METHODS: The ANRS VESPA2 cross-sectional survey (April 2011-January 2012) collected socio-demographic, medical and behavioral data from 3,022 PLHIV recruited in 73 French HIV hospital departments...
2017: PloS One
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