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https://www.readbyqxmd.com/read/28432938/the-role-of-distress-intolerance-in-the-relationship-between-childhood-sexual-abuse-and-problematic-alcohol-use-among-latin-american-msm
#1
Katie Wang, Jaclyn M White Hughto, Katie B Biello, Conall O'Cleirigh, Kenneth H Mayer, Joshua G Rosenberger, David S Novak, Matthew J Mimiaga
BACKGROUND: Despite the high prevalence of childhood sexual abuse (CSA) among men who have sex with men (MSM) and its well-documented association with substance use in adulthood, little research has examined the psychological mechanisms underlying this association. The current study utilized a large, multinational sample of MSM in Latin America to examine the role of distress intolerance (i.e., decreased capacity to withstand negative psychological states) in the relationship between childhood sexual abuse history and problematic alcohol use...
April 6, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28432579/hcv-cure-and-reinfection-among-people-with-hiv-hcv-coinfection-and-people-who-inject-drugs
#2
REVIEW
Marianne Martinello, Behzad Hajarizadeh, Jason Grebely, Gregory J Dore, Gail V Matthews
PURPOSE OF REVIEW: Highly effective, well-tolerated interferon-free direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) therapeutics, with the opportunity for broad treatment scale-up among marginalised or "high-risk" populations, including people who inject drugs (PWID) and people with HIV/HCV coinfection. RECENT FINDINGS: Concern that HCV reinfection may compromise HCV treatment outcomes is sometimes cited as a reason for not offering treatment to current and former PWID...
April 21, 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28432206/identifying-factors-that-lead-to-the-persistence-of-imported-gonorrhoeae-strains-a-modelling-study
#3
Ben B Hui, David M Whiley, Basil Donovan, Matthew G Law, David G Regan
OBJECTIVE: The importation of Neisseria gonorrhoeae (NG) strains from overseas is believed to be the main source of antimicrobial resistance in Australia. With recent sporadic cases of ceftriaxone-resistant gonorrhoea reported in Australia and elsewhere, we sought to model the potential for imported NG strains to persist in the men who have sex with men (MSM) population in Australia. METHODS: We developed an individual-based model to simulate the transmission of NG in a population of urban MSM, and used this model to investigate factors contributing to the probability that an imported NG strain will persist...
May 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28431923/sources-of-racial-disparities-in-hiv-prevalence-in-men-who-have-sex-with-men-in-atlanta-ga-usa-a-modelling-study
#4
Steven M Goodreau, Eli S Rosenberg, Samuel M Jenness, Nicole Luisi, Sarah E Stansfield, Gregorio A Millett, Patrick S Sullivan
BACKGROUND: In the USA, men who have sex men (MSM) are at high risk for HIV, and black MSM have a substantially higher prevalence of infection than white MSM. We created a simulation model to assess the strength of existing hypotheses and data that account for these disparities. METHODS: We built a dynamic, stochastic, agent-based network model of black and white MSM aged 18-39 years in Atlanta, GA, USA, that incorporated race-specific individual and dyadic-level prevention and risk behaviours, network attributes, and care patterns...
April 18, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28428838/a-national-strategic-plan-for-reducing-the-burden-of-sexually-transmitted-infections-in-israel-by-the-year-2025
#5
Daniel Chemtob, Dan Gandacu, Zohar Mor, Itamar Grotto, Emilia Anis, Elliot Rosenberg
BACKGROUND: There is on ongoing debate in the literature regarding the real burden of STIs (sexually transmitted infections) in Western countries and the proper strategies needed to estimate and to prevent them. Our purpose is to present an evidence-based national strategic plan for STI prevention in Israel through assessing the current burden of illness, leading international preventive strategies, and practical policymaking experience. METHODS: Epidemiologic and health policy data on STIs were analyzed from various sources: a) systematic national surveillance data for the years 2002-2014; b) the international scientific literature (published between 2002-16; keywords: Sexually Transmitted Diseases (STD) (or STI) AND prevention AND intervention AND gonorrhea OR chlamydia OR syphilis; c) internal Ministry of Health (MOH) analyses and reports, and d) expert opinion...
2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/28427377/a-comprehensive-overview-of-urogenital-anorectal-and-oropharyngeal-neisseria-gonorrhoeae-testing-and-diagnoses-among-different-sti-care-providers-a-cross-sectional-study
#6
Casper D J den Heijer, Christian J P A Hoebe, Geneviève A F S van Liere, Jan E A M van Bergen, Jochen W L Cals, Frans S Stals, Nicole H T M Dukers-Muijrers
BACKGROUND: Gonorrhoea, caused by Neisseria gonorrhoeae (NG), can cause reproductive morbidity, is increasingly becoming resistant to antibiotics and is frequently asymptomatic, which shows the essential role of NG test practice. In this study we wanted to compare NG diagnostic testing procedures between different STI care providers serving a defined geographic Dutch region (280,000 inhabitants). METHODS: Data on laboratory testing and diagnosis of urogenital and extragenital (i...
April 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28426357/a-qualitative-assessment-of-alcohol-consumption-and-sexual-risk-behaviors-among-men-who-have-sex-with-men-and-transgender-women-in-peru
#7
Panagiotis Vagenas, Shan-Estelle Brown, Jesse L Clark, Kelika A Konda, Javier R Lama, Jorge Sánchez, Ann C Duerr, Frederick L Altice
BACKGROUND: Peruvian men who have sex with men (MSM) and transgender women (TGW) experience the double burden of a highly concentrated HIV epidemic with a high prevalence of alcohol use disorders (AUDs). Recent research has associated both with risky sexual behaviors, including unprotected sex, having multiple sexual partners, engaging in sex work, having recent sexually transmitted infections, and having HIV-infected partners. AUDs have also been associated in MSM/TGW with being unaware of HIV+ status...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28425903/improving-linkage-to-hiv-care-at-low-threshold-sti-hiv-testing-sites-an-evaluation-of-the-immediate-staging-pilot-project-in-vancouver-british-columbia
#8
Bobbi Brownrigg, Darlene Taylor, Felicia Phan, Irvine Sandstra, Rochelle Stimpson, Rolando Barrios, Richard Lester, Gina Ogilvie
OBJECTIVES: The objective of the Immediate Staging Pilot Project (ISPP) was to improve linkage to human immunodeficiency virus (HIV) care by increasing the number of referrals made to HIV care, and to decrease the time between diagnosis and linkage to care for newly diagnosed HIV clients. This pilot had the potential to decrease HIV transmission at a population level by engaging clients in treatment earlier. SETTING: The Bute Street Clinic and Health Initiative for Men Clinic on Davie in Vancouver, British Columbia are low-threshold public health facilities providing HIV/STI testing primarily to men who have sex with men (MSM)...
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28422615/understanding-how-sexual-and-gender-minority-stigmas-influence-depression-among-trans-women-and-men-who-have-sex-with-men-in-india
#9
Venkatesan Chakrapani, Pandara Purayil Vijin, Carmen H Logie, Peter A Newman, Murali Shunmugam, Murugesan Sivasubramanian, Miriam Samuel
PURPOSE: Few studies have assessed how sexual and gender minority stigmas affect the mental health of trans women and self-identified men who have sex with men (MSM) in India, populations with a high HIV burden. We tested whether social support and resilient coping act as mediators of the effect of sexual and gender minority stigmas on depression as proposed by Hatzenbuehler's psychological mediation framework, or as moderators based on Meyer's minority stress theory. METHODS: We conducted a cross-sectional survey among trans women (n = 300) and MSM (n = 300) recruited from urban and rural sites in India...
April 19, 2017: LGBT Health
https://www.readbyqxmd.com/read/28419198/increased-syphilis-testing-of-men-who-have-sex-with-men-greater-detection-of-asymptomatic-early-syphilis-and-relative-reduction-in-secondary-syphilis
#10
Eric P F Chow, Denton Callander, Christopher K Fairley, Lei Zhang, Basil Donovan, Rebecca Guy, David A Lewis, Margaret Hellard, Phillip Read, Alison Ward, Marcus Y Chen
Background: Syphilis rates have increased markedly among men who have sex with men (MSM) in many countries. This study examined trends in syphilis testing and detection of early syphilis among MSM in Australia. Methods: Serial cross-sectional analyses on syphilis testing and diagnoses among MSM attending a national sentinel network of 46 sexual health clinics in Australia between 2007 and 2014. Results: There were 359,313 clinic visits included in the analysis, with 32% of clinic visits for HIV-positive MSM...
April 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28418232/high-pre-exposure-prophylaxis-uptake-and-early-adherence-among-men-who-have-sex-with-men-and-transgender-women-at-risk-for-hiv-infection-the-prep-brasil-demonstration-project
#11
Brenda Hoagland, Ronaldo I Moreira, Raquel B De Boni, Esper G Kallas, José Valdez Madruga, Ricardo Vasconcelos, Silvia Goulart, Thiago S Torres, Luana M S Marins, Peter L Anderson, Paula M Luz, Iuri da Costa Leite, Albert Y Liu, Valdilea G Veloso, Beatriz Grinsztejn
INTRODUCTION: The efficacy of pre-exposure prophylaxis (PrEP) in preventing sexual acquisition of human immunodeficiency virus (HIV) is well established. Little is known about the feasibility of PrEP implementation in middle-income settings with concentrated epidemics among men who have sex with men (MSM) and transgender women (TGW). METHODS: PrEP Brasil is a prospective, multicentre, open-label demonstration project assessing PrEP delivery in the context of the Brazilian Public Health System...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28412290/lack-of-decline-in-hepatitis-c-virus-incidence-among-hiv-positive-men-who-have-sex-with-men-during-1990-2014
#12
Daniela Katinka Van Santen, Jannie Johanna Van Der Helm, Julia Del Amo, Laurence Meyer, Antonella D'arminio Monforte, Matt Price, Charles Antoine Béguelin, Robert Zangerle, Mette Sannes, Kholoud Porter, Ronald Bertus Geskus, Maria Prins
BACKGROUND AND AIMS: Hepatitis C virus (HCV) incidence among HIV-positive men who have sex with men (MSM) has increased since 2000, though regional differences have been documented in recent years. We aimed to 1) estimate trends in HCV incidence among HIV-positive MSM, 2) assess the association between incidence and geographical region, age and HIV-related measurements and, 3) assess temporal changes in time from HIV seroconversion to HCV infection. METHODS: We used data from MSM with well-estimated dates of HIV seroconversion from the CASCADE Collaboration (1990-2014)...
April 12, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28411524/the-network-structure-of-sex-partner-meeting-places-reported-by-hiv-infected-msm-opportunities-for-hiv-targeted-control
#13
Meredith Brantley, Christina Schumacher, Jamie Perin, Amelia Greiner Safi, Jonathan M Ellen, Ravikiran Muvva, Patrick Chaulk, Jacky M Jennings
Baltimore, Maryland ranks among U.S. cities with the highest incidence of HIV infection among men who have sex with men (MSM). HIV screening at sex partner meeting places or venues frequented by MSM with new diagnoses and/or high HIV viral load may reduce transmission by identifying and linking infected individuals to care. We investigated venue-based clustering of newly diagnosed MSM to identify high HIV transmission venues. HIV surveillance data from MSM diagnosed between October 2012-June 2014 and reporting ≥1 sex partner meeting place were examined...
April 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28407646/assessing-the-performance-of-3-human-immunodeficiency-virus-incidence-risk-scores-in-a-cohort-of-black-and-white-men-who-have-sex-with-men-in-the-south
#14
Jeb Jones, Martin Hoenigl, Aaron J Siegler, Patrick S Sullivan, Susan Little, Eli Rosenberg
BACKGROUND: Risk scores have been developed to identify men at high risk of human immunodeficiency virus (HIV) seroconversion. These scores can be used to more efficiently allocate public health prevention resources, such as pre-exposure prophylaxis. However, the published scores were developed with data sets that comprise predominantly white men who have sex with men (MSM) collected several years prior and recruited from a limited geographic area. Thus, it is unclear how well these scores perform in men of different races or ethnicities or men in different geographic regions...
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28407644/mobile-phone-and-internet-use-mostly-for-sex-seeking-and-associations-with-sexually-transmitted-infections-and-sample-characteristics-among-black-african-american-and-hispanic-latino-men-who-have-sex-with-men-in-3-us-cities
#15
Jacob E Allen, Gordon Mansergh, Matthew J Mimiaga, Jeremy Holman, Jeffrey H Herbst
BACKGROUND: Men who have sex with men (MSM) have a relatively high prevalence of sexually transmitted infections (STIs). This study examines the association of self-reported STIs and use of mobile phones and/or computer-based Internet to meet sexual partners among black and Hispanic/Latino MSM in the United States. METHODS: Black and Hispanic/Latino MSM (N = 853) were recruited from 3 US cities (Chicago, IL; Kansas City, MO; and Fort Lauderdale, FL) via online and community outreach...
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28406992/expanded-antiretroviral-treatment-sexual-networks-and-condom-use-treatment-as-prevention-unlikely-to-succeed-without-partner-reduction-among-men-who-have-sex-with-men-in-china
#16
Jie Lou, Peipei Hu, Han-Zhu Qian, Yuhua Ruan, Zhen Jin, Hui Xing, Yiming Shao, Sten H Vermund
BACKGROUND: To project the impact of partner reduction on preventing new HIV infections among men who have sex with men (MSM) under varying conditions of enhanced HIV testing and treatment (T&T) and condom use in Beijing, China. METHODS AND FINDINGS: A complex network model was fitted to predict the number of new HIV infections averted from 2014 to 2023 under four scenarios of sexual behavior risk reduction (S)-S1: Male sexual partners decrease (reduced by a random value m from 1-50) while condom use increases (risk constant p is a random value between 0...
2017: PloS One
https://www.readbyqxmd.com/read/28406520/the-folding-mechanism-and-key-metastable-state-identification-of-the-prp127-147-monomer-studied-by-molecular-dynamics-simulations-and-markov-state-model-analysis
#17
Shuangyan Zhou, Qianqian Wang, Yuwei Wang, Xiaojun Yao, Wei Han, Huanxiang Liu
The structural transition of prion proteins from a native α-helix (PrP(C)) to a misfolded β-sheet-rich conformation (PrP(Sc)) is believed to be the main cause of a number of prion diseases in humans and animals. Understanding the molecular basis of misfolding and aggregation of prion proteins will be valuable for unveiling the etiology of prion diseases. However, due to the limitation of conventional experimental techniques and the heterogeneous property of oligomers, little is known about the molecular architecture of misfolded PrP(Sc) and the mechanism of structural transition from PrP(C) to PrP(Sc)...
April 13, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28406274/barriers-and-facilitators-to-hiv-testing-among-young-men-who-have-sex-with-men-and-transgender-women-in-kingston-jamaica-a-qualitative-study
#18
Carmen H Logie, Ashley Lacombe-Duncan, Natasha Brien, Nicolette Jones, Nakia Lee-Foon, Kandasi Levermore, Annecka Marshall, Laura Nyblade, Peter A Newman
INTRODUCTION: Young men who have sex with men (MSM) in Jamaica have the highest HIV prevalence in the Caribbean. There is little information about HIV among transgender women in Jamaica, who are also overrepresented in the Caribbean epidemic. HIV-related stigma is a barrier to HIV testing among Jamaica's general population, yet little is known of MSM and transgender women's HIV testing experiences in Jamaica. We explored perceived barriers and facilitators to HIV testing among young MSM and transgender women in Kingston, Jamaica...
March 3, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28406271/the-relationship-between-higher-social-trust-and-lower-late-hiv-diagnosis-and-mortality-differs-by-race-ethnicity-results-from-a-state-level-analysis
#19
Yusuf Ransome, Ashley Batson, Sandro Galea, Ichiro Kawachi, Denis Nash, Kenneth H Mayer
INTRODUCTION: Black men who have sex with men (MSM) continue to suffer a disproportionate burden of new HIV diagnoses and mortality. To better understand some of the reasons for these profound disparities, we examined whether the association between social trust and late HIV diagnosis and mortality differed by race/ethnicity, and investigated potential indirect effects of any observed differences. METHODS: We performed generalized structural equation modelling to assess main and interaction associations between trust among one's neighbours in 2009 (i...
April 6, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28406270/community-engagement-in-sexual-health-and-uptake-of-hiv-testing-and-syphilis-testing-among-msm-in-china-a-cross-sectional-online-survey
#20
(no author information available yet)
INTRODUCTION: HIV and syphilis testing rates remain low among men who have sex with men (MSM) in low- and middle-income countries (LMICs). Community engagement has been increasingly used to promote HIV testing among key populations in high-income countries, often in settings with stronger civil society. This study aimed to assess socio-demographic, behavioural, and community engagement factors associated with HIV and syphilis testing among MSM in China. METHODS: MSM ≥16 years old who had condomless sex in the past three months were recruited nationwide to complete a cross-sectional online survey in November 2015...
February 6, 2017: Journal of the International AIDS Society
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