keyword
MENU ▼
Read by QxMD icon Read
search

Crossed hypersensitivity

keyword
https://www.readbyqxmd.com/read/29773475/concordance-between-aspergillus-specific-precipitating-antibody-and-igg-in-allergic-bronchopulmonary-aspergillosis
#1
Kazuki Harada, Tsuyoshi Oguma, Akemi Saito, Yuma Fukutomi, Jun Tanaka, Katsuyoshi Tomomatsu, Masami Taniguchi, Koichiro Asano
BACKGROUND: Several serological tests for specific precipitin or IgG are available to demonstrate type III hypersensitivity reactions to Aspergillus species and are essential for infectious fungal disease diagnosis. These assays are also important for allergic bronchopulmonary aspergillosis (ABPA) diagnosis; however, their concordance in ABPA was not well studied. METHODS: Fifty-two ABPA patients diagnosed based on ISHAM criteria were enrolled. Precipitins and IgG specific to Aspergillusfumigatus, Aspergillusniger, Aspergillusflavus, or Aspergillusterreus were measured using Ouchterlony double immunodiffusion tests and ImmunoCAP method, respectively...
May 15, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29766368/systemic-contact-dermatitis
#2
REVIEW
Marcella Aquino, Greg Rosner
Systemic contact dermatitis (SCD) traditionally refers to a skin condition where an individual who is cutaneously sensitized to an allergen will subsequently react to that same allergen or a cross reacting allergen via a different route. It occurs to allergens including metals, medications, and foods. The exact pathophysiology underlying this disease remains unknown, although it appears to be mediated by type 4 hypersensitivity reactions and possibly type 3 hypersensitivity reactions. The p-I concept (pharmacologic interaction with immunoreceptors) hypothesized that drugs are able to bind directly to a T cell receptor without first being presented by MHC (major histocompatibility complex) molecules and without prior metabolism, which would help explain why SCD can be seen on first exposure to medications...
May 15, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29765217/allergy-to-chlorpromazine-and-valproic-acid-following-carbamazepine-hypersensitivity-in-a-patient-with-an-hla-b-4601-allele
#3
Kumi Sakurada, Takeshi Kozaru, Kazuo Yamada, Masashi Nibuya, Kiyoshi Nagata, Eiji Suzuki
A 73-year-old man, exhibiting psychomotor excitement after traumatic brain injury, developed allergic cutaneous eruptions and hepatic inflammation that did not resolve after the cessation of carbamazepine (CBZ). Fusing maculopapular erythema was observed in the face, neck, presternal region, and bilaterally in the forearms and feet. A drug-induced lymphocyte stimulation test revealed hypersensitivity to chlorpromazine (CPZ) and valproic acid (VPA), as well as to CBZ. The allergic reaction with eosinophilia to CPZ and VPA was suspected to have emerged following CBZ hypersensitivity, since previous treatment with CPZ and VPA prior to the introduction of CBZ had not been associated with adverse reactions earlier in the course of treatment...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29756383/a-novel-affective-motivational-based-overground-system-for-detecting-spinal-cord-injury-associated-thermal-and-mechanical-hypersensitivity-in-rats
#4
Elizabeth A Dugan, Jacqueline Sagen
BACKGROUND: Preclinical research for neuropathic pain has depended primarily on the use of behavioral nociceptive testing that is sensory-discriminatory based and reflexive in nature. This can be particularly problematic in spinal cord injury (SCI) associated neuropathic pain research where hyperreflexia may develop thus confounding interpretation of reflexive responses as pain symptoms. To address this, we have designed an affective-motivational based Overground System that has interchangeable floors to allow examination of nociceptive behaviors in response to mechanical and cold stimuli prior to and following spinal cord injury...
May 14, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29756087/from-acute-to-persistent-low-back-pain-a-longitudinal-investigation-of-somatosensory-changes-using-quantitative-sensory-testing-an-exploratory-study
#5
Anna Marcuzzi, Paul J Wrigley, Catherine M Dean, Petra L Graham, Julia M Hush
Introduction: Chronic low back pain (LBP) is commonly associated with generalised pain hypersensitivity. It is suggested that such somatosensory alterations are important determinants for the transition to persistent pain from an acute episode of LBP. Although cross-sectional research investigating somatosensory function in the acute stage is developing, no longitudinal studies designed to evaluate temporal changes have been published. Objectives: This exploratory study aimed to investigate the temporal development of somatosensory changes from the acute stage of LBP to up to 4 months from onset...
March 2018: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29751529/the-use-and-safety-of-tnf-inhibitors-during-pregnancy-in-women-with-psoriasis-a-review
#6
REVIEW
Cæcilie Bachdal Johansen, Espen Jimenez-Solem, Ann Haerskjold, Freja Lærke Sand, Simon Francis Thomsen
Psoriasis is a chronic immune-mediated inflammatory disease affecting women of childbearing potential. Biologic agents, notably Tumor Necrosis Factor inhibitors (TNFi), are the only current non-contraindicated systemic treatment option during pregnancy. TNFi comprised of complete immunoglobulin G (IgG) antibodies antibodies (adalimumab, golimumab, and infliximab) actively cross the placenta from the second trimester and are detectable in the child up to one year postpartum. Data on safety of TNFi are conflicting; however a trend towards drug-specific harm has been reported, with increased risk of congenital malformations and preterm birth...
May 3, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29732295/self-reported-prevalence-of-clinical-features-of-allergy-to-nuts-and-seeds-and-seafood-in-university-students
#7
Ma Victoria Domínguez-García, Miriam V Flores-Merino, Cecilia Puente-Fernández, Jaime Morales-Romero, Martín Bedolla-Barajas
Background: In developing countries, there is a lack of epidemiological information related to food hypersensitivity, including nuts and seafood. Objective: The aim was to determine the prevalence of allergic reactions and clinical manifestations associated with the consumption of nuts and seeds or seafood in university students. Methods: We designed an observational cross-sectional study. A structured questionnaire was applied to Mexican university students to identify allergic reactions associated with the consumption of nuts and seeds, and seafood...
April 2018: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29729441/laryngeal-dysfunction-in-cough-hypersensitivity-syndrome-a-cross-sectional-observational-study
#8
Anne E Vertigan, Sarah M Kapela, Emily K Kearney, Peter G Gibson
BACKGROUND: Chronic refractory cough(CRC), a phenotype of Cough Hypersensitivity Syndrome(CHS), is a disabling problem. Laryngeal dysfunction may be important in CC and CHS because laryngeal symptoms are common and CC, however the role of laryngeal dysfunction in CHS has not been systematically examined. OBJECTIVE: To determine the nature of laryngeal dysfunction in patients with CC and compare with the related laryngeal conditions of Vocal Cord Dysfunction(VCD) and Muscle Tension Dysphonia(MTD)...
May 2, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29723936/-latex-papaya-syndrome-an-infrequent-association
#9
Victoria Rojas-Mandujano, Kitzia González-Juárez, Cecilia Hernández-Fernández, Patricia María O'Farrill-Romanillos, Leonel Del Rivero, Diana Andrea Herrera-Sánchez
BACKGROUND: Latex-fruit syndrome (LFS) is characterized by allergy to latex and plants. Papain, chymopapain, caricaine and class I chitinases are papaya's most allergenic proteins. The similarity between latex hevein epitopes and papaya class I chitinases might explain the latex-papaya syndrome (LPS). OBJECTIVE: To describe the clinical characteristics of patients with LPS. METHODS: Cross-sectional, observational, descriptive study where 11 patients diagnosed with latex allergy by skin prick test and clinically diagnosed with papaya-induced anaphylaxis were included...
January 2018: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29723336/cross-cultural-adaptation-of-the-brazilian-version-of-the-dentine-hypersensitivity-experience-questionnaire-dheq-15
#10
Dhelfeson Willya Douglas-De-Oliveira, Frederico Santos Lages, Saul Martins Paiva, Jennifer Grace Cromley, Peter Glenn Robinson, Luís Otávio Miranda Cota
The dentine hypersensitivity (DH) is able to impair the oral health related quality of life (OHRQoL). However, there isn't any specific validated questionnaire to be used in Brazil. The objective was to adapt and to validate the English version of the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15) for use in Brazil. DHEQ-15 was cross-culturally adapted into the Brazilian-Portuguese language and then validated in a cross-sectional study with 100 participants recruited at a University clinic. Study sample comprised 2 groups: 100 individuals with DH, and 100 individuals without...
2018: Brazilian Oral Research
https://www.readbyqxmd.com/read/29690828/evidence-for-increased-mri-signal-intensity-and-morphological-changes-in-the-brachial-plexus-and-median-nerves-of-patients-with-chronic-arm-and-neck-pain-following-whiplash-injury
#11
Jane Greening, Kamakshi Anantharaman, Rupert Young, Andrew Dilley
Study Design Cross-sectional study. Background Whiplash following a motor vehicle accident can result in chronic neck and arm pain. Patients frequently present with cutaneous hypersensitivities and hypoesthesia but without obvious clinical sign of nerve injury. T2-weighted magnetic resonance imaging (MRI) has previously been used to identify nerve pathology. Objectives To determine whether there are signs of peripheral nerve pathology on MRI in patients with chronic arm and neck pain following whiplash injury...
April 24, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29683226/low-incidence-of-heparin-induced-skin-lesions-in-orthopedic-surgery-patients-with-low-molecular-weight-heparins
#12
M Schindewolf, M Paulik, H Kroll, R Kaufmann, M Wolter, W-H Boehncke, E Lindhoff-Last, A Recke, R J Ludwig
BACKGROUND: Heparins are widely prescribed for prevention and therapy of arterial and venous thromboembolic diseases. Heparin-induced skin lesions are the most frequent adverse effects of subcutaneous heparin treatment in non-surgical patients (7.5-39.8%); no data exist on surgical patients. Commonly, they are due to a delayed-type hypersensitivity reaction (DTH), but may also be a manifestation of life-threatening heparin-induced thrombocytopenia (HIT). Lesions of both entities resemble initially...
April 23, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29673741/cross-sectional-observational-study-exploring-clinical-risk-of-titanium-allergy-caused-by-dental-implants
#13
Maki Hosoki, Keisuke Nishigawa, Toyoko Tajima, Mayu Ueda, Yoshizo Matsuka
PURPOSE: Studies have reported cases of metal allergy caused by titanium-containing materials. We wished to clarify the relationship between titanium allergy and dental implants by describing patients who suffered allergic symptoms after they had received such implants. METHODS: A total of 270 patients who visited a Dental Metal Allergy Clinic at Tokushima University Hospital from April 2010 to March 2014 were the study cohort. Patch testing with 28 types of metal allergens (including four titanium allergens) was undertaken for patients...
April 16, 2018: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/29649050/temporal-bone-histopathology-in-cockayne-syndrome
#14
Ophir Handzel, Joseph B Nadol
: Cockayne syndrome (CS) is a rare autosomal recessive syndrome resulting in defective DNA repair. Its features include cachectic dwarfism, hearing loss, skin hypersensitivity to sunlight, premature aging, and dementia. Presented is a right temporal bone of a patient who died at the age of 29 years. The clinical course was compatible with type 1 CS, the classical form. Homozygous missense variant in the ERCC6 gene (Excision Repair Cross-Complementation group 6) was found, compatible with CS complementation group B...
April 11, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29621411/the-southern-sweden-adolescent-allergy-cohort-prevalence-of-allergic-diseases-and-cross-sectional-associations-with-individual-and-social-factors
#15
Therese Sterner, Ada Uldahl, Åke Svensson, Jonas Björk, Cecilia Svedman, Christel Nielsen, Alf Tunsäter, Magnus Bruze, Hampus Kiotseridis
OBJECTIVES: Asthma and allergic diseases are the most frequent chronic diseases in childhood worldwide, and considered a burden for the affected children and their families. The diseases impose an economic burden on society if not diagnosed and treated properly and management of and these diseases are challenging for healthcare professionals. The aim of the present investigation was to assess the prevalence of allergic diseases in an unselected cohort of adolescents in southern Sweden...
April 5, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29614487/prevalence-of-hypersensitivity-reactions-in-children-associated-with-acetaminophen-a-systematic-review-and-meta-analysis
#16
Sofianne Gabrielli, Alexandra Langlois, Moshe Ben-Shoshan
BACKGROUND: Acetaminophen is the most commonly used antipyretic in children. However, there are limited data assessing hypersensitivity reactions related to acetaminophen usage. OBJECTIVES: To conduct a systematic review to characterize reported reactions to acetaminophen in adults and children, and perform a meta-analysis to assess the prevalence of acetaminophen hypersensitivity in children with a suspected acetaminophen allergy. METHODS: We performed a systematic review of studies reporting hypersensitivity reactions to acetaminophen by searching 2 electronic databases...
April 3, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29599676/cross-sensitization-to-artemisia-and-ambrosia-pollen-allergens-in-an-area-located-outside-of-the-current-distribution-range-of-ambrosia
#17
Łukasz Grewling, Dorota Jenerowicz, Paweł Bogawski, Matt Smith, Małgorzata Nowak, Agata Frątczak, Magdalena Czarnecka-Operacz
Introduction: The role of long-distance transported (LDT) Ambrosia pollen in inducing new sensitization and affecting sensitization rates in Artemisia -sensitized patients is unclear. Aim: The aim of this study was to estimate the degree of cross-sensitization to Ambrosia/Artemisi a allergens in citizens of Poznan (Western Poland). This area is covered by extensive Artemisia populations but does not currently have local Ambrosia populations. Material and methods: Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of Artemisia vulgaris and Ambrosia artemisiifolia , an allergenic component of A...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29584543/distinguishing-molecular-features-of-allergic-fungal-rhinosinusitis
#18
Matthew A Tyler, Caroline J Padro Dietz, Chris B Russell, Martin J Citardi, Shervin Assassi, Jun Ying, Amber U Luong
Objective Allergic fungal rhinosinusitis (AFRS) is a clinical subtype of chronic rhinosinusitis with nasal polyps (CRSwNP), characterized by eosinophilic mucin, evidence of fungal elements within the mucin, fungal-specific type I hypersensitivity, and characteristic computed tomography findings. It remains controversial whether AFRS represents a disease with a unique pathophysiology from chronic rhinosinusitis or is merely a severe form of CRSwNP. The goal of this study was to identify molecular features unique to AFRS...
March 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29573291/digital-analysis-yields-more-reliable-and-accurate-measures-of-dermal-and-epidermal-thickness-in-histologically-processed-specimens-compared-to-traditional-methods
#19
Sergey Y Turin, Joanna K Ledwon, Hanna Bae, Adrian Buganza-Tepole, Jolanta Topczewska, Arun K Gosain
Changes in the thickness of the dermis and epidermis have been described in the scenario of tissue expansion as well as inflammatory skin processes (psoriasis, contact hypersensitivity and so on). These changes have previously been quantified by using ocular micrometers to obtain and then average a limited number of spot measurements, leading to suboptimal accuracy. We describe a rapid method of using freely available Image J software to analyze digitized images of fixed skin specimens. By determining the cross-sectional area and surface length of a skin layer, a simple calculation produces more accurate and reproducible measurements of its thickness compared to historical methods, with excellent inter-rate reliability...
March 24, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29540595/role-of-the-e2-hypervariable-region-hvr1-in-the-immunogenicity-of-a-recombinant-hcv-vaccine
#20
John L M Law, Michael Logan, Jason Wong, Juthika Kundu, Darren Hockman, Amir Landi, Chao Chen, Kevin Crawford, Mark Wininger, Janelle Johnson, Catalina Mesa Prince, Elzbieta Dudek, Ninad Mehta, D Lorne Tyrrell, Michael Houghton
Current evidence supports a protective role for virus neutralizing antibodies in immunity against HCV infection. Many cross-neutralizing monoclonal antibodies have been identified. These antibodies have been shown to protect or clear infection in animal models. Previous clinical trials have shown a gpE1/gpE2 vaccine can induce antibodies that neutralize the in vitro infectivity of all the major HCVcc genotypes around the world. However, cross-neutralization appeared to favour certain genotypes with significant but lower neutralization against others...
March 14, 2018: Journal of Virology
keyword
keyword
106858
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"