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Pinitol AND Pax4

Un-Hee Kim, Jeong-Hyun Yoon, Hua Li, Ji-Hyun Kang, Hyeon-Seon Ji, Ki Hun Park, Dong-Ha Shin, Ho-Yong Park, Tae-Sook Jeong
In Korea, soy (Glycine max (L.) Merr.) leaves are eaten as a seasonal vegetable or pickled in soy sauce. Ethyl acetate extracts of soy leaves (EASL) are enriched in pterocarpans and have potent α-glucosidase inhibitory activity. This study investigated the molecular mechanisms underlying the anti-diabetic effect of EASL in C57BL/6J mice with high-fat diet (HFD)-induced type 2 diabetes. Mice were randomly divided into normal diet (ND), HFD (60 kcal% fat diet), EASL (HFD with 0.56% (wt/wt) EASL), and Pinitol (HFD with 0...
2014: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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