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Preterm, apnea, very low weight

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https://www.readbyqxmd.com/read/27405054/impact-of-feeding-method-on-diaphragm-electrical-activity-and-central-apnea-in-preterm-infants-feadi-study
#1
Eugene Ng, Patti Schurr, Maureen Reilly, Michael Dunn, Jennifer Beck
BACKGROUND: In preterm infants, it is unknown whether feeding affects neural breathing pattern. OBJECTIVES: By measuring the diaphragm electrical activity (Edi) waveform, we evaluated the effect of enteral feeding and compared the effects of feeding methods on neural breathing pattern and central apnea in very low birth weight preterm infants. METHODS: In a prospective, randomized, crossover study, ten non-ventilated preterm infants with birth weights<1250g and tolerating full feeds were randomized to either bolus feeding (BF) or slow infusion feeding (SF) over 90min, followed by crossover to the other method at the next feed...
October 2016: Early Human Development
https://www.readbyqxmd.com/read/27075527/co-bedding-in-neonatal-nursery-for-promoting-growth-and-neurodevelopment-in-stable-preterm-twins
#2
REVIEW
Nai Ming Lai, Siew Cheng Foong, Wai Cheng Foong, Kenneth Tan
BACKGROUND: The increased birth rate of twins during recent decades and the improved prognosis of preterm infants have resulted in the need to explore measures that could optimize their growth and neurodevelopmental outcomes. It has been postulated that co-bedding simulates twins' intrauterine experiences in which co-regulatory behaviors between them are observed. These behaviors are proposed to benefit twins by reducing their stress, which may promote growth and development. However, in practice, uncertainty surrounds the benefit-risk profile of co-bedding...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26963049/stochastic-modeling-of-central-apnea-events-in-preterm-infants
#3
Matthew T Clark, John B Delos, Douglas E Lake, Hoshik Lee, Karen D Fairchild, John Kattwinkel, J Randall Moorman
A near-ubiquitous pathology in very low birth weight infants is neonatal apnea, breathing pauses with slowing of the heart and falling blood oxygen. Events of substantial duration occasionally occur after an infant is discharged from the neonatal intensive care unit (NICU). It is not known whether apneas result from a predictable process or from a stochastic process, but the observation that they occur in seemingly random clusters justifies the use of stochastic models. We use a hidden-Markov model to analyze the distribution of durations of apneas and the distribution of times between apneas...
April 2016: Physiological Measurement
https://www.readbyqxmd.com/read/26957524/diagnostic-evaluation-and-home-monitor-use-in-late-preterm-to-term-infants-with-apnea-bradycardia-and-desaturations
#4
Lauren Veit, Michael Amberson, Christina Freiberger, Brian Montenegro, Sagori Mukhopadhyay, Lawrence M Rhein
Apnea, bradycardia, and oxygen desaturation events are a common in neonatal intensive care units, with relevant literature to date largely focusing on very low birth weight and extremely low birth weight infants. We conducted a retrospective review of infants born at ≥34 weeks gestational age at 2 tertiary neonatal intensive care units in Boston, MA, between January 2009 and December 2013. Our objectives included (1) describing the diagnostic evaluations performed in late preterm to term infants with discharge-delaying apnea, bradycardia, or oxygen desaturation events and (2) identifying variables associated with home monitor use...
March 7, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/26341125/factors-associated-with-red-blood-cell-transfusions-in-very-low-birth-weight-preterm-infants-in-brazilian-neonatal-units
#5
Amelia Miyashiro Nunes dos Santos, Ruth Guinsburg, Maria Fernanda Branco de Almeida, Renato Soibelman Procianoy, Sergio Tadeu Martins Marba, Walusa Assad Gonçalves Ferri, Ligia MariaSuppo de Souza Rugolo, José Maria Andrade Lopes, Maria Elisabeth Lopes Moreira, Jorge Hecker Luz, Maria Rafaela Conde González, Jucille do Amaral Meneses, Regina Vieira Cavalcante da Silva, Vânia Olivetti Steffen Abdallah, José Luiz Muniz Bandeira Duarte, Patricia Franco Marques, Maria Albertina Santiago Rego, Navantino Alves Filho, Vera Lúcia Jornada Krebs
BACKGROUND: Preterm infants in neonatal intensive care units frequently receive red blood cells (RBC) transfusions due to the anemia of prematurity. A number of variables related to gestational age, severity of illness and transfusion practices adopted in the neonatal unit where the neonate was born may contribute to the prescription of RBC transfusions. This study aimed to analyse the frequency and factors associated with RBC transfusions in very-low-birth-weight preterm infants. METHODS: A prospective cohort of 4283 preterm infants (gestational age: 29...
2015: BMC Pediatrics
https://www.readbyqxmd.com/read/26307940/differences-in-mortality-and-morbidity-according-to-gestational-ages-and-birth-weights-in-infants-with-trisomy-18
#6
Ken Imai, Atsushi Uchiyama, Tomoka Okamura, Mako Ago, Hideyo Suenaga, Eri Sugita, Hideko Ono, Kyoko Shuri, Kenichi Masumoto, Satsuki Totsu, Hidehiko Nakanishi, Satoshi Kusuda
The aim of this study was to clarify the effects of gestational age and birth weight on outcomes of the infants. Medical records of 36 infants with trisomy 18 admitted to Tokyo Women's Medical University Hospital from 1991 to 2012 were reviewed retrospectively. We compared clinical characteristics between term infants (n = 15) and preterm infants (n = 21). There were one very-low-birth-weight (VLBW) term infant (5%) and 12 VLBW preterm infants (80%). Although there were no significant differences in clinical characteristics and provided management between the two groups, none of the preterm infants achieved survival to discharge...
November 2015: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/26058963/regional-spinal-epidural-caudal-versus-general-anaesthesia-in-preterm-infants-undergoing-inguinal-herniorrhaphy-in-early-infancy
#7
REVIEW
Lisa J Jones, Paul D Craven, Anil Lakkundi, Jann P Foster, Nadia Badawi
BACKGROUND: With improvements in neonatal intensive care, more preterm infants are surviving the neonatal period and presenting for surgery in early infancy. Inguinal hernia is the most common condition requiring early surgery, appearing in 38% of infants whose birth weight is between 751 grams and 1000 grams. Approximately 20% to 30% of otherwise healthy preterm infants having general anaesthesia for inguinal hernia surgery at a postmature age have at least one apnoeic episode within the postoperative period...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26014694/-risk-factors-for-extrauterine-growth-restriction-in-preterm-infants-with-gestational-age-less-than-34-weeks
#8
Wei Cao, Yong-Hong Zhang, Dong-Ying Zhao, Hong-Ping Xia, Tian-Wen Zhu, Li-Juan Xie
OBJECTIVE: To investigate the correlated factors contributed to extrauterine growth restriction (EUGR) in preterm infants with the gestational age less than 34 weeks. METHODS: A total of 694 preterm infants with the gestational ages less than 34 weeks were enrolled. They were classified into EUGR and non-EUGR groups by weight on discharge. The perinatal data, growth data, nutritional information and morbidities during hospitalization were compared between the two groups...
May 2015: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/25784749/predicting-severe-motor-impairment-in-preterm-children-at-age-5-years
#9
MULTICENTER STUDY
Anne Synnes, Peter J Anderson, Ruth E Grunau, Deborah Dewey, Diane Moddemann, Win Tin, Peter G Davis, Lex W Doyle, Gary Foster, May Khairy, Chukwuma Nwaesei, Barbara Schmidt
OBJECTIVE: To determine whether the ability to predict severe motor impairment at age 5 years improves between birth and 18 months. DESIGN: Ancillary study of the Caffeine for Apnea of Prematurity Trial. SETTING AND PATIENTS: International cohort of very low birth weight children who were assessed sequentially from birth to 5 years. OUTCOME MEASURES: Severe motor impairment was defined as a score <5th percentile on the Movement Assessment Battery of Children (MABC), or inability to complete the MABC because of cerebral palsy...
August 2015: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/25753873/usefulness-of-duopap-in-the-treatment-of-very-low-birth-weight-preterm-infants-with-neonatal-respiratory-distress-syndrome
#10
RANDOMIZED CONTROLLED TRIAL
B Zhou, J-F Zhai, H-X Jiang, Y Liu, B Jin, Y-Y Zhang, J-B Wu
OBJECTIVE: This study examined the usefulness of nasal Duo positive airway pressure (DuoPAP) in the treatment of very low birth weight preterm infants with neonatal respiratory distress syndrome (NRDS). PATIENTS AND METHODS: Eighty-five very low birth weight preterm infants with NRDS were randomly divided into two groups. Forty-five infants were treated with DuoPAP, while 40 infants were treated using nasal continuous positive airway pressure (nCPAP). The study outcomes were pH, PaCO, PaO₂, oxygenation index (PaO₂/FiO₂), and the number of failure cases at 1, 12, and 24 hours after non-invasive respiratory support...
February 2015: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/25549762/very-long-apnea-events-in-preterm-infants
#11
Mary A Mohr, Brooke D Vergales, Hoshik Lee, Matthew T Clark, Douglas E Lake, Anne C Mennen, John Kattwinkel, Robert A Sinkin, J Randall Moorman, Karen D Fairchild, John B Delos
Apnea is nearly universal among very low birth weight (VLBW) infants, and the associated bradycardia and desaturation may have detrimental consequences. We describe here very long (>60 s) central apnea events (VLAs) with bradycardia and desaturation, discovered using a computerized detection system applied to our database of over 100 infant years of electronic signals. Eighty-six VLAs occurred in 29 out of 335 VLBW infants. Eighteen of the 29 infants had a clinical event or condition possibly related to the VLA...
March 1, 2015: Journal of Applied Physiology
https://www.readbyqxmd.com/read/24141616/nasal-cpap-in-the-delivery-room-for-newborns-with-extremely-low-birth-weight-in-a-hospital-in-a-developing-country
#12
W A Gonçalves-Ferri, F E Martinez
The objective of this study was to determine the feasibility of the use of continuous positive airway pressure installed prophylactically in the delivery room (DR-CPAP), for infants with a birth weight between 500 and 1000 g in settings with limited resources. During 23 months, infants with a birth weight between 500 and 1000 g consecutively received DR-CPAP. A total of 33 infants with low birth weight were enrolled, 16 (48.5%) were females. Only 14 (42.4%) received antenatal corticosteroids and only 2 of those 14 (14...
October 2013: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/23899805/safety-and-effectiveness-of-skin-to-skin-contact-in-the-nicu-to-support-neurodevelopment-in-vulnerable-preterm-infants
#13
COMPARATIVE STUDY
Aurélia Carbasse, Sylvie Kracher, Martine Hausser, Claire Langlet, Benoît Escande, Lionel Donato, Dominique Astruc, Pierre Kuhn
Skin-to-skin contact (SSC) is a cornerstone of neurodevelopmentally supportive and family-oriented care for very low-birth-weight preterm infants (VPIs). However, performing SSC with unstable and/or ventilated VPIs remains challenging for caregiving teams and/or controversial in the literature. We first aimed to assess the safety and effectiveness of SSC with vulnerable VPIs in a neonatal intensive care unit over 12 months. Our second aim was to evaluate the impact of the respiratory support (intubation or not) and of the infant's weight (above or below 1000 g) on the effects of SSC...
July 2013: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/23897918/mask-versus-nasal-tube-for-stabilization-of-preterm-infants-at-birth-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
C Omar F Kamlin, Kim Schilleman, Jennifer A Dawson, Enrico Lopriore, Susan M Donath, Georg M Schmölzer, Frans J Walther, Peter G Davis, Arjan B Te Pas
OBJECTIVE: Positive-pressure ventilation (PPV) using a manual ventilation device and a face mask is recommended for compromised newborn infants in the delivery room (DR). Mask ventilation is associated with airway obstruction and leak. A nasal tube is an alternative interface, but its safety and efficacy have not been tested in extremely preterm infants. METHODS: An unblinded randomized controlled trial was conducted in Australia, and the Netherlands. Infants were stratified by gestational age (24-25/26-29 weeks) and center...
August 2013: Pediatrics
https://www.readbyqxmd.com/read/23592319/accurate-automated-apnea-analysis-in-preterm-infants
#15
Brooke D Vergales, Alix O Paget-Brown, Hoshik Lee, Lauren E Guin, Terri J Smoot, Craig G Rusin, Matthew T Clark, John B Delos, Karen D Fairchild, Douglas E Lake, Randall Moorman, John Kattwinkel
OBJECTIVE: In 2006 the apnea of prematurity (AOP) consensus group identified inaccurate counting of apnea episodes as a major barrier to progress in AOP research. We compare nursing records of AOP to events detected by a clinically validated computer algorithm that detects apnea from standard bedside monitors. STUDY DESIGN: Waveform, vital sign, and alarm data were collected continuously from all very low-birth-weight infants admitted over a 25-month period, analyzed for central apnea, bradycardia, and desaturation (ABD) events, and compared with nursing documentation collected from charts...
February 2014: American Journal of Perinatology
https://www.readbyqxmd.com/read/23488612/n-sippv-versus-bi-level-n-cpap-for-early-treatment-of-respiratory-distress-syndrome-in-preterm-infants
#16
COMPARATIVE STUDY
Alberto Ricotti, Vincenzo Salvo, Luc J I Zimmermann, Antonio W D Gavilanes, Ignazio Barberi, Gianluca Lista, Micaela Colivicchi, Francesca Temporini, Diego Gazzolo
OBJECTIVE: Non-invasive ventilation (NIV) for RDS in extremely/very low birth-weight infants represents the new challenge for neonatologists. In this regard, data comparing the effectiveness of Bi-Level-NCPAP (BiPAP) versus nasal synchronized intermittent positive pressure ventilation (NSIPPV) as primary mode of treatment for RDS are lacking. STUDY DESIGN: We conducted a retrospective study from December 2007 to December 2010 in seventy-eight infants, who received NIV (N-SIPPV: 33; BiPAP: 45)...
September 2013: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/23134911/maternal-and-foetal-risk-factor-and-complication-with-immediate-outcome-during-hospital-stay-of-very-low-birth-weight-babies
#17
M A Mannan, N Jahan, S K Dey, M F Uddin, S Ahmed
This prospective study was done to find out the maternal and foetal risk factors and complications during hospital stay. It was conducted in Special Care Neonatal Unit (SCANU), Department of Child Health, Bangabandhu Memorial Hospital (BBMH), University of Science and Technology Chittagong (USTC) from1st October 2001 to 30th March 2002 and cases were 35 very low birth weight (VLBW) newborns. Common complications of VLBW babies of this series were frequent apnea (40%), Septicemia (25.71%), Hypothermia (17.14%), NEC (14...
October 2012: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/22929600/kangaroo-care-and-behavioral-and-physiologic-pain-responses-in-very-low-birth-weight-twins-a-case-study
#18
Xiaomei Cong, Regina M Cusson, Naveed Hussain, Di Zhang, Sharon P Kelly
The purpose of this case study was to describe pain responses in three study conditions: longer (30 minutes) kangaroo care (KC) before and throughout heel stick (KC30), shorter (15 minutes) KC before and throughout heel stick (KC15), and incubator care throughout heel stick (IC) in 28-week gestational age twins. Pain responses were measured by crying time, Preterm Infant Pain Profile (PIPP), and heart rate variability indexes, including low-frequency power (LF, representing sympathetic activity), high-frequency power (HF, parasympathetic activity), and LF/HF ratio (sympathetic-parasympathetic balance)...
September 2012: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/22543544/adverse-cardiorespiratory-events-following-primary-vaccination-of-very-low-birth-weight-infants
#19
C Meinus, G Schmalisch, S Hartenstein, H Proquitté, C C Roehr
OBJECTIVE: To examine the relationship between primary vaccination of preterm infants and prevalence ratios of associated factors for unwanted cardiorespiratory events, following the recommendation of the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices for immunization of preterm infants at 2 months of chronological age. METHODS: Two-year retrospective study of very low birth weight infants receiving their primary vaccination...
March 2012: Jornal de Pediatria
https://www.readbyqxmd.com/read/22253394/survival-without-disability-to-age-5-years-after-neonatal-caffeine-therapy-for-apnea-of-prematurity
#20
RANDOMIZED CONTROLLED TRIAL
Barbara Schmidt, Peter J Anderson, Lex W Doyle, Deborah Dewey, Ruth E Grunau, Elizabeth V Asztalos, Peter G Davis, Win Tin, Diane Moddemann, Alfonso Solimano, Arne Ohlsson, Keith J Barrington, Robin S Roberts
CONTEXT: Very preterm infants are prone to apnea and have an increased risk of death or disability. Caffeine therapy for apnea of prematurity reduces the rates of cerebral palsy and cognitive delay at 18 months of age. OBJECTIVE: To determine whether neonatal caffeine therapy has lasting benefits or newly apparent risks at early school age. DESIGN, SETTING, AND PARTICIPANTS: Five-year follow-up from 2005 to 2011 in 31 of 35 academic hospitals in Canada, Australia, Europe, and Israel, where 1932 of 2006 participants (96...
January 18, 2012: JAMA: the Journal of the American Medical Association
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