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Eda Cengiz, Peiyao Cheng, Katrina J Ruedy, Craig Kollman, William V Tamborlane, Georgeanna J Klingensmith, Robin L Gal, Janet Silverstein, Joyce Lee, Maria J Redondo, Roy W Beck
OBJECTIVE: Current data are limited on the course of type 1 diabetes (T1D) in children and adolescents through the first few years of diabetes. The Pediatric Diabetes Consortium T1D new onset (NeOn) Study was undertaken to prospectively assess natural history and clinical outcomes in children treated at 7 US diabetes centers from the time of diagnosis. This paper describes clinical outcomes in the T1D NeOn cohort during the first 3 years postdiagnosis. RESULTS: A total of 1048 participants (mean age 9...
October 19, 2016: Pediatric Diabetes
Jonathan C W Edwards
It is widely perceived that there is a problem in giving a naturalistic account of mental representation that deals adequately with the issue of meaning, interpretation, or significance (semantic content). It is suggested here that this problem may arise partly from the conflation of two vernacular senses of representation: representation-as-origin and representation-as-input. The flash of a neon sign may in one sense represent a popular drink, but to function as a representation it must provide an input to a 'consumer' in the street...
2016: Frontiers in Psychology
J J Bailey, A S Kadyrov, I B Abdurakhmanov, D V Fursa, I Bray
Stopping powers of H, He, H2, and H2O targets for antiprotons have been calculated using a convergent close-coupling method. For He and H2 targets electron-electron correlations are fully accounted for using a multiconfiguration approximation. Two-electron processes are included using an independent-event model. The water molecule is described using a neon-like structure model with a pseudo-spherical potential. Results are tabulated for the purpose of Monte Carlo simulations to model antiproton transport through matter for radiation therapy...
October 11, 2016: Physica Medica: PM
Wenjie Yu, Xing Liu, Bing Xu, Xiaopeng Xing, Xuefeng Wang
The novel noble-gas complexes NgBeSO2 (Ng=Ne, Ar, Kr, Xe) have been prepared in the laser-evaporated beryllium atom reactions with SO2 in low-temperature matrices. Doped with heavier noble gas, the guest (Ar, Kr, Xe) atom can substitute neon to form more stable complex. Infrared spectroscopy and theoretical calculations are used to confirm the band assignment. The dissociation energies are calculated at 0.9, 4.0, 4.7, and 6.0 kcal/mol for NeBeSO2, ArBeSO2, KrBeSO2, and XeBeSO2, respectively, at the CCSD(T) level...
October 11, 2016: Journal of Physical Chemistry. A
C Bopp, R Hirayama, T Inaniwa, A Kitagawa, N Matsufuji, K Noda
Ion beams present a potential advantage in terms of treatment of lesions with hypoxic regions. In order to use this potential, it is important to accurately model the cell survival of oxic as well as hypoxic cells. In this work, an adaptation of the microdosimetric kinetic (MK) model making it possible to account for cell hypoxia is presented. The adaptation relies on the modification of damage quantity (double strand breaks and more complex lesions) due to the radiation. Model parameters such as domain size and nucleus size are then adapted through a fitting procedure...
October 7, 2016: Physics in Medicine and Biology
Idoia Berges, David Antón, Jesús Bermúdez, Alfredo Goñi, Arantza Illarramendi
BACKGROUND: One of the current research efforts in the area of biomedicine is the representation of knowledge in a structured way so that reasoning can be performed on it. More precisely, in the field of physiotherapy, information such as the physiotherapy record of a patient or treatment protocols for specific disorders must be adequately modeled, because they play a relevant role in the management of the evolutionary recovery process of a patient. In this scenario, we introduce TRHONT, an application ontology that can assist physiotherapists in the management of the patients' evolution via reasoning supported by semantic technology...
October 4, 2016: Journal of Biomedical Semantics
G Goldsztejn, T Marchenko, R Püttner, L Journel, R Guillemin, S Carniato, P Selles, O Travnikova, D Céolin, A F Lago, R Feifel, P Lablanquie, M N Piancastelli, F Penent, M Simon
Using synchrotron radiation and high-resolution electron spectroscopy, we have directly observed and identified specific photoelectrons from K^{-2}V states in neon corresponding to simultaneous 1s ionization and 1s→valence excitation. The natural lifetime broadening of the K^{-2}V states and the relative intensities of different types of shakeup channels have been determined experimentally and compared to ab initio calculations. Moreover, the high-energy Auger spectrum resulting from the decay of Ne^{2+}K^{-2} and Ne^{+}K^{-2}V states as well as from participator Auger decay from Ne^{+}K^{-1}L^{-1}V states, has been measured and assigned in detail utilizing the characteristic differences in lifetime broadenings of these core hole states...
September 23, 2016: Physical Review Letters
A Hult Roos, J H D Eland, J Andersson, S Zagorodskikh, R Singh, R J Squibb, R Feifel
We show that the proportion of double Auger decay following creation of single 1s core holes in molecules containing C, N and O atoms is greater than usually assumed, amounting to about 10% of single Auger decay in many cases. It varies from molecule to molecule, where the size of the molecule has a positive correlation to the amount of double Auger decay. In neon, examined as a related benchmark, the proportion of double Auger decay is similar to that in methane, and is in the order of 5%.
September 14, 2016: Physical Chemistry Chemical Physics: PCCP
S I Zaichkina, A R Dyukina, O M Rozanova, S P Romanchenko, N P Sirota, E A Kuznetsova, N B Simonova, S S Sorokina, D T Zakrzhevskaya, V I Yusupov, V N Bagratishvili
We studied the effect of exposure to helium-neon laser (dose range 0.16-50 mJ/cm(2)) on activation of natural protection reserve in mice using the adaptive response test. DNA comets method revealed a protective response manifested in DNA damage level in whole blood leukocytes of mice and in lymphoid organs by the thymus and spleen weight index; preexposure to laser did not induce the adaptive response. ROS level in the whole blood was assessed by the level of zymosan-induced luminol chemiluminescence. In mice subjected to adaptive laser irradiation in doses of 0...
September 2016: Bulletin of Experimental Biology and Medicine
Surendrababu P Swathy, Kodsara Ramachandra Kiran, Madhura S Rao, Krishna K Mahato, Mattu Radhakrishna Rao, Kapaettu Satyamoorthy, Annamalai Muthusamy
Exposure to laser irradiation on seeds brings about the changes in agronomical characteristics of the plants. Solanum melongena L. var. Mattu Gulla, a variety of brinjal is of high economic value due to its unique colour and flavour. The aim of the study was to understand the influence of Helium-Neon (He-Ne) laser irradiation on agronomical characters of Solanum melongena L. var. Mattu Gulla in the field conditions. Various growth characteristics including seed germination percentage, survival rate, plant height, number of branches, and flowers and fruits were estimated during different developmental stages of the brinjal...
September 8, 2016: Journal of Photochemistry and Photobiology. B, Biology
Somaye Fallahnezhad, Abbas Piryaei, Faraj Tabeie, Hamid Nazarian, Hasan Darbandi, Abdoldllah Amini, Ataroalsadat Mostafavinia, Seyed Kamran Ghorishi, Ali Jalalifirouzkouhi, Mohammad Bayat
No abstract text is available yet for this article.
September 1, 2016: Journal of Biomedical Optics
J E Calvert, Han Xu, A J Palmer, R D Glover, D E Laban, X M Tong, A S Kheifets, K Bartschat, I V Litvinyuk, D Kielpinski, R T Sang
This work describes the first observations of the ionisation of neon in a metastable atomic state utilising a strong-field, few-cycle light pulse. We compare the observations to theoretical predictions based on the Ammosov-Delone-Krainov (ADK) theory and a solution to the time-dependent Schrödinger equation (TDSE). The TDSE provides better agreement with the experimental data than the ADK theory. We optically pump the target atomic species and measure the ionisation rate as the a function of different steady-state populations in the fine structure of the target state which shows significant ionisation rate dependence on populations of spin-polarised states...
September 26, 2016: Scientific Reports
Maryna Vlasiuk, Federico Frascoli, Richard J Sadus
The thermodynamic, structural, and vapor-liquid equilibrium properties of neon are comprehensively studied using ab initio, empirical, and semi-classical intermolecular potentials and classical Monte Carlo simulations. Path integral Monte Carlo simulations for isochoric heat capacity and structural properties are also reported for two empirical potentials and one ab initio potential. The isobaric and isochoric heat capacities, thermal expansion coefficient, thermal pressure coefficient, isothermal and adiabatic compressibilities, Joule-Thomson coefficient, and the speed of sound are reported and compared with experimental data for the entire range of liquid densities from the triple point to the critical point...
September 14, 2016: Journal of Chemical Physics
S M Afzal, M A N Razvi, Salman A Khan, Osman I Osman, Ahmed H Bakry, Abdullah M Asiri
Novel heterocyclic azomethine dyes were prepared by the reaction of anthracene-9-carbaldehyde with different heterocyclic amines under microwave irradiation. Structures of the azomethine dyes were confirmed by the elemental analysis, mass spectrometry and several spectroscopic techniques. We studied absorbance and fluorescence spectra of the azomethine dyes in various solvents. They are found to be good absorbers and emitters. We also report photophysical properties like, extinction coefficient, oscillator strength, stokes shift and transition dipole moment...
2016: PloS One
A C Brown, H W van der Hart
We propose a novel scheme for resolving the contribution of inner- and outer-valence electrons in extreme-ultraviolet (XUV)-initiated high-harmonic generation in neon. By probing the atom with a low-energy (below the 2s ionization threshold) ultrashort XUV pulse, the 2p electron is steered away from the core, while the 2s electron is enabled to describe recollision trajectories. By selectively suppressing the 2p recollision trajectories, we can resolve the contribution of the 2s electron to the high-harmonic spectrum...
August 26, 2016: Physical Review Letters
George H Booth, Theodoros Tsatsoulis, Garnet Kin-Lic Chan, Andreas Grüneis
We present a simple, robust, and black-box approach to the implementation and use of local, periodic, atom-centered Gaussian basis functions within a plane wave code, in a computationally efficient manner. The procedure outlined is based on the representation of the Gaussians within a finite bandwidth by their underlying plane wave coefficients. The core region is handled within the projected augment wave framework, by pseudizing the Gaussian functions within a cutoff radius around each nucleus, smoothing the functions so that they are faithfully represented by a plane wave basis with only moderate kinetic energy cutoff...
August 28, 2016: Journal of Chemical Physics
Lester Andrews, Han-Gook Cho
Laser ablated Ti, Zr, and Hf atoms react with phosphine during condensation in excess argon or neon at 4 K to form metal hydride insertion phosphides (H2P-MH) and metal dihydride phosphinidenes (HP═MH2) with metal phosphorus double bonds, which are characterized by their intense metal-hydride stretching frequencies. Both products are formed spontaneously on annealing the solid matrix samples, which suggests that both products are relaxed from the initial higher energy M-PH3 intermediate complex, which is not observed...
September 6, 2016: Inorganic Chemistry
Min Kyo Yin, Jeong Sik Lim, Dong Min Moon, Gae Ho Lee, Jeongsoon Lee
Excimer lasers, widely used in the semiconductor industry, are crucial for analyzing the purity of premix laser gases for the purpose of controlling stable laser output power. In this study, we designed a system for analyzing impurities in pure neon (Ne) base gas by customized GC. Impurities in pure neon (H2 and He), which cannot be analyzed at the sub-μmol/mol level using commercial GC detectors, were analyzed by a customized pulsed-discharge Ne ionization detector (PDNeD) and a pressurized injection thermal conductivity detector using Ne as the carrier gas (Pres...
September 9, 2016: Journal of Chromatography. A
Siew Yong Teo, Mei Yeng Yew, Siang Yin Lee, Michael J Rathbone, Seng Neon Gan, Allan G A Coombes
Phenytoin-loaded alkyd nanoemulsions were prepared spontaneously using the phase inversion method from a mixture of novel biosourced alkyds and Tween 80 surfactant. Exposure of human adult keratinocytes (HaCaT cells) for 48 h to alkyd nanoemulsions producing phenytoin concentrations of 3.125-200 μg/mL resulted in relative cell viability readings using tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide of 100% confirming nontoxicity and suggesting cell proliferation activity. Phenytoin-loaded alkyd nanoemulsions generally resulted in higher mean cell viability compared with equivalent concentration of phenytoin solutions, suggesting that the nanoemulsions provided a controlled-release property that maintained the optimum phenytoin level for keratinocyte growth...
August 11, 2016: Journal of Pharmaceutical Sciences
Elisabet Gimeno, Vicenç Quera, Francesc S Beltran, Ruth Dolado
Fish can gain significant adaptive advantages when living in a group and they exhibit a wide variety of types of collective motion. The scientific literature recognizes 2 main patterns: shoals (aggregations of individuals that remain close to each other), and schools (aggregations of aligned, or polarized, individuals). We analyzed the collective motion of 2 social fish species, zebrafish (Danio rerio) and black neon tetra (Hyphessobrycon herbertaxelrodi), and compared their patterns of movement and the effect of group size and environmental constraints such as water column height and tank geometry on the collective motion of both species...
August 11, 2016: Journal of Comparative Psychology
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