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Breast ultra Sound

Shabnam Farzaneh, Elnaz Zainalzadeh, Bahram Daraei, Soraya Shahhosseini, Afshin Zarghi
Background Due to the astonishing properties of ferrocene and its derivatives, it has a broad application in diverse areas. Numerous ferrocene derivatives demonstrated anti-proliferative activity. Also COX-2, as a key isoenzyme for production of prostaglandins, is frequently overexpressed in various cancers. It is now recognized that COX-2 over expression promotes tumorigenic functions which can be suppressed by COX-2 inhibitors, a phenomenon useful for the preventing of tumor progression. The combination of COX-2 inhibitors with other anti-cancer or cancer prevention drugs may reduce their side effects in future cancer prevention and treatment...
October 3, 2017: Anti-cancer Agents in Medicinal Chemistry
Mikkel G Mieritz, Peter Christiansen, Martin Blomberg Jensen, Ulla N Joensen, Loa Nordkap, Inge A Olesen, A Kirstine Bang, Anders Juul, Niels Jørgensen
OBJECTIVE: Gynaecomastia is a benign proliferation of glandular tissue of the breast; however, it is an important clinical observation because it can be the first symptom of an underlying disease. Some controversy exists concerning the clinical importance of an in-depth investigation of men who develop gynaecomastia. We hypothesise that a thorough work-up is required in adult men with gynaecomastia. DESIGN: All adult men (n = 818) referred to a secondary level andrological department at Rigshospitalet in Copenhagen, Denmark during a four-year period (2008-2011) under the diagnosis of gynaecomastia (ICD-10: N62) were included...
May 2017: European Journal of Endocrinology
Stina Klasson, Johan Nyman, Henry Svensson, Patrik Velander
OBJECTIVE: Reconstruction with deep inferior epigastric perforator flap (DIEP) is considered to be the first choice for autologous breast reconstruction. The primary aims of this retrospective study were to find out if differences in smoking habits and BMI are useful predictors for postoperative complications in DIEP surgery. METHODS: Three hundred and one patients were included. Data regarding smoking habits, BMI, age at surgery, total and final flap weight, abdominal scars, parity, number of perforators, chemotherapy, post mastectomy radiation therapy, and preoperative mapping of perforators with either Computer Tomography Angiography or hand-held ultra sound Doppler were collected...
December 2016: Journal of Plastic Surgery and Hand Surgery
O Gentilini, E Botteri, P Dadda, C Sangalli, C Boccardo, N Peradze, R Ghisini, V Galimberti, P Veronesi, A Luini, E Cassano, G Viale, U Veronesi
BACKGROUND: The SOUND (Sentinel node vs. Observation after axillary Ultra-souND) trial is an ongoing prospective randomized study comparing sentinel node biopsy vs. no axillary surgical staging in patients with small breast cancer and negative pre-operative ultra-sound of the axilla. PATIENTS AND METHODS: The first 180 recruited patients were administered the QuickDASH (Disability Arm and Shoulder) questionnaire at different time points (before surgery, 1 week, 6 months and 1 year after surgery) to evaluate the physical function of the ipsilateral upper limb, The QuickDASH score ranges from 0 (no disability) to 100 (complete disability)...
May 2016: European Journal of Surgical Oncology
V Pineau, A De Runz, J-P Fyad, E Simon, F Marchal
SUBJECT: A recent report from "Agence Nationale de sécurité du medicament et des produits de santé" (ANSM) assesses the rupture of silicone gel breast implants without proposing rules for follow-up and replacement of implants. OBJECTIVE: To demonstrate that systematic follow-up surveillance of silicone breast implants could improve early diagnosis of ruptures; to propose a surveillance protocol based on the findings. MATERIALS AND METHODS: This is a multicentric, retrospective study which reports cases of ruptured silicone gel breast implants from January 2006 to June 2014...
December 2015: Annales de Chirurgie Plastique et Esthétique
Bhamar Lal, Jai Pal Paryani, Shafique-ur-Rehman Memon
BACKGROUND: Bladder calculi are one of the commonest health problems in young children especially in rural and underprivileged areas. METHODS: All children of bladder stones operated at District Headquarter Hospital Mithi from July 2009 to June 2012 were included in this cross-sectional study. Data was collected regarding age, sex, address (rural or urban), body weight, duration of breast feeding, weaning, detailed dietary history regarding milk type, volume, amount of water intake, recurrent diarrhoea, urinary tract infection (UTI), family history, and socioeconomic history...
January 2015: Journal of Ayub Medical College, Abbottabad: JAMC
Jimmy Okello, Harriet Kisembo, Sam Bugeza, Moses Galukande
BACKGROUND: Mammography, the gold standard for breast cancer screening misses some cancers, especially in women with dense breasts. Breast ultrasonography as a supplementary imaging tool for further evaluation of symptomatic women with mammographically dense breasts may improve the detection of mass lesions otherwise missed at mammography. The purpose of this study was to determine the incremental breast cancer detection rate using US scanning in symptomatic women with mammographically dense breasts in a resource poor environment...
December 30, 2014: BMC Medical Imaging
Shoko Otsuka, Naoki Watanabe, Youko Sasaki, Reiko Shimojima
BACKGROUND: Nevertheless in breast conserving surgery, the dissection of inferior part of breast mound will cause severe deformity, which affects the patient's quality of life adversely. We have used an infra-mammary adipofascial tissue to repair the defect, and breast mound could be reconstructed concurrently in primary breast cancer surgery. PATIENTS AND SURGICAL PROCEDURE: From September 2009 to June 2012, we performed the infra-mammary adipofascial tissue repair (IATR) on 25 patients with breast cancer in inferior site of their breast mound...
November 2015: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Betty Tuong, Ian Gardiner
OBJECTIVE: Many indications for breast MRI exist. MRI screening can identify preinvasive breast cancer in women at high risk and in that regard is superior to mammography and ultrasound. Quality control standards exist for mammography and breast ultra-sound screening with phantoms designed specifically for this purpose. Given the growing importance of breast MRI, we propose the development of a breast MRI phantom for quality control purposes. MATERIALS AND METHODS: A breast phantom with dual cavities containing water and fat was developed...
September 2013: AJR. American Journal of Roentgenology
Omar Quaba, Awf Quaba
INTRODUCTION: To determine the true rupture rates of PIP implants from a large single surgeon cohort and to assess whether rupture rates varied depending on time of implant insertion. In addition, the efficacy of ultra sound scanning (USS) in determining rupture is examined. DESIGN: Predominantly prospectively based analysis of patient records, investigations and surgical findings. PARTICIPANTS: 338 patients (676 implants) were included in the study and they all had removal of their implants...
September 2013: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Beatriz Adrada, Yun Wu, Wei Yang
OBJECTIVE: Breast ultrasound is helpful in the characterization of masses to differentiate benign from malignant disease. The internal echotexture of a mass is an important ultra-sound feature in breast diagnostic workup. This article reviews the imaging and histopathology findings of benign and malignant hyperechoic masses to better recognize these conditions. CONCLUSION: Hyperechoic masses are frequently benign, including hematoma, fat necrosis, abscess, and benign neoplasm...
May 2013: AJR. American Journal of Roentgenology
Oreste Gentilini, Umberto Veronesi
Sentinel lymph node biopsy (SLNB) is the standard approach for axillary staging in patients with early breast cancer. Recent data showed no outcome difference in patients with positive sentinel node between axillary dissection vs no further axillary surgery, raising doubts on the role of SLNB itself. Therefore, a new trial was designed comparing SLNB vs observation when axillary ultra-sound is negative in patients with small breast cancer candidates to breast conserving surgery.
October 2012: Breast: Official Journal of the European Society of Mastology
Daniel Richard Leff, Charles Vincent, Ragheed Al-Mufti, Deborah Cunningham, Ara Darzi, Dimitri J Hadjiminas
BACKGROUND: The introduction of the National Health Service (NHS) Breast Screening Programme has led to a considerable increase in the detection of impalpable breast cancer. Patients with impalpable breast cancer typically undergo oncological resection facilitated either by the insertion of guide wires placed stereo-tactically or through ultra-sound guided skin markings to delineate the extent of a lesion. The need for radiological interventions on the day of surgery adds complexity and introduces the risk that a patient may accidentally transferred to the operating room directly without the image guidance procedure...
2012: Patient Safety in Surgery
Eivind Ystrom
BACKGROUND: Neonatal anxiety and depression and breastfeeding cessation are significant public health problems. There is an association between maternal symptoms of anxiety and depression and early breastfeeding cessation. In earlier studies, the causality of this association was interpreted both ways; symptoms of anxiety and depression prepartum significantly impacts breastfeeding, and breastfeeding cessation significantly impacts symptoms of anxiety and depression.First, we aimed to investigate whether breastfeeding cessation is related to an increase in symptoms of anxiety and depression from pregnancy to six months postpartum...
2012: BMC Pregnancy and Childbirth
Melissa M Sanders, Shamaela Waheed, Sanjay Joshi, Caroline Pogson, Stephen R Ebbs
INTRODUCTION: To ensure appropriate axillary surgery is performed at a single operation, we have sought to identify patients with involved nodes who might progress directly to axillary dissection. PATIENTS AND METHODS: We evaluated pre-operative ultrasound of the axilla and intra-operative frozen section of sentinel lymph nodes over a 3-year period. Patients with clinical early breast cancer underwent axillary ultrasound. Abnormal nodes were defined as a cortex > 2...
March 2011: Annals of the Royal College of Surgeons of England
M Galukande, E Kiguli-Malwadde
The incidence of breast cancer in sub-Saharan nations is increasing. There is a worsening scarcity of Human Resource for Health in Uganda in particular and Sub Saharan Africa in general. Resources available for health care are predominantly spent on infectious disease care such as (HIV/AIDS, Tuberculosis and Malaria). These factors and more make the future of breast cancer care including screening in Sub Saharan African grim.Although mass breast cancer screening by mammography has been proved to be efficacious in the developed nations of the world, this has not been replicated in the developing nations because mass screening is not yet possible for the reasons stated...
March 2010: African Health Sciences
Kyung Jin Lee, Wan-Kyu Oh, Jooyoung Song, Sojin Kim, Jiwoon Lee, Jyongsik Jang
Novel polymer based photoluminescent nanoparticles were fabricated by ultra-sound induced emulsion polymerization and applied to bioimaging of human breast cancer SK-BR-3 cells after ethylenediamine treatment and conjugation with anti-ErbB2 antibody.
August 7, 2010: Chemical Communications: Chem Comm
Sophie Taïeb, Luc Ceugnart
The contribution of breast MR imaging for second intention after a complete assessment (mammography, ultra-sound, and possibly histological) of breast pathology is not any more to show. Its limits are due primarily to its great sensitivity responsible for false positive (20 to 40 %) and to the difficulty in carrying out biopsies under guidance IRM of the lesions not found in second intention by the mammography and ultrasound (50 to 75 %). Its use reasoned by respecting the indications recognized as useful and validated for the clinical plan is an imperative condition to avoid noxious assumptions of responsibility of the patients...
January 2008: Bulletin du Cancer
François Eisinger
Screening for breast cancer in high-risk women could be seen through the general criteria for cancer screening. The attributable part of BRCA in breast cancer is estimated to be between 2 and 5%. For these women, breast cancer screening lay between prevention with low risk/benefit efficacy and prophylactic mastectomy with high efficacy but low acceptability. Risk reduction could be achieve with "classic" screening tools (examination, mammography and ultra sound) but should soon benefit from MRI experimental protocols...
October 2005: Bulletin du Cancer
Lisa A Newman, Tara A Washington
Breast conservation therapy for early-stage invasive breast cancer provides survival equivalent to mastectomy. Careful patient selection and surgical technique are necessary to minimize local recurrence. Extensive studies of breast conservation therapy over the past 15 years have identified risk factors for local recurrence, and have proven that certain cases previously thought to be ineligible for lumpectomy (such as occult breast cancer, locally advanced breast cancer, macromastia, and cancer in pregnant patients), can be safely managed with modified BCT approaches...
August 2003: Surgical Clinics of North America
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