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Pakinson's disease

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https://www.readbyqxmd.com/read/23898514/-autophagy-promoted-by-pakinson-s-disease-related-protein-pink1
#1
Ming-Ming Tong, Chang-An Jiang
OBJECTIVE: To investigate the function of Parkinson's disease (PD)-related protein Pink1 in autophagy. METHODS: Pink1, autophagy inhibitor Bcl-XL and autophagy induced-factor Beclin1 were amplified with RT-PCR and contructed into pcDNA3. 1 (+) vector. The stable HEK293 cell line of Pink1 expression was established through the lentivirus system. Pink1, Bcl-XL and Beclin1 were tansfected into the HEK293 Cell Line. Co-Immunoprecipitation and Western blot were performed to determine the interaction between Pink1 and Bcl-XL, the effect of Pink1 on the interaction between Bcl-XL and Beclin1, and the function of Pink1 in autophagy...
May 2013: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/22611616/-vascular-or-lower-body-parkinsonism-rise-and-fall-of-a-diagnosis
#2
REVIEW
Imre Szirmai
UNLABELLED: The "arteriosclerotic parkinsonism", which is called vascular parkinsonism (VP), was first described by Critchley'. The broad based slow gait, reduced stride lenght, start hesitation, freezing and paratonia was mentioned as "lower body parkinsonism" (LBP) which can be associated by slow speech, dysexecutive syndrome, and hand tremor of predominantly postural character. In VP the DAT-scan proved normal dopamine content of the striatum in contrast with Parkinson's disease (PD)...
November 30, 2011: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/20180380/-quality-of-life-of-patient-with-schizophrenia-treated-by-conventional-and-atypical-neuroleptics
#3
COMPARATIVE STUDY
Lilia Zaghdoudi, W Homri, S Belaid, M Ben Bechir, Raja Labbane
BACKGROUND: the quality of life of patients suffering from schizophrenia was extensively studied but it seems that impact on quality of life of neuroleptics, particularly atypical antipsychotic treatment was not clearly elucidated. AIMS: In this study we have compared the impact on quality of life of atypical antipsychotic versus classic neuroleptics. METHODS: We have enrolled, prospectively, all patients with schizophrenia as confirmed by DSM-IV TR...
September 2009: La Tunisie Médicale
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