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Navin Kapur

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https://www.readbyqxmd.com/read/27970368/tct-196-from-door-to-balloon-to-door-to-unload-a-transcriptomic-analysis-identifies-that-primary-unloading-globally-shifts-gene-expression-and-preserves-mitochondrial-integrity-within-the-infarct-zone-during-the-acute-phase-of-ami
#1
Michele Esposito, Yali Zhang, Gavin Schnitzler, Vikram Paruchuri, Xiaoying Qiao, Shiva Annamalai, Emily Mackey, Kevin Morine, Andrew Mullin, Tobias Rheude, Catalina Breton, Richard Karas, Noam Josephy, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970301/tct-135-increased-circulating-plasma-free-hemoglobin-levels-not-lactate-dehydrogenase-levels-identify-hemolysis-among-patients-with-cardiogenic-shock-treated-with-an-impella-micro-axial-flow-catheter
#2
Michele Esposito, Ryan O'Kelly, Nima Aghili, Shiva Annamalai, Anas Hamadeh, Michael Kiernan, Amanda Vest, David DeNofrio, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970296/tct-132-utility-of-the-save-score-as-a-predictor-of-survival-in-cardiogenic-shock-requiring-va-ecmo-or-impella-for-acute-mechanical-circulatory-support
#3
Sudeep Kuchibhotla, Michele Esposito, David Zisa, Ryan O'Kelly, Shiva Annamalai, Adel Ghuloom, Leslie Lussier, Catalina Breton, Tobias Rheude, Andrew Mullin, Carey Kimmelstiel, Michael Kiernan, Amanda Vest, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970291/tct-126-simultaneous-not-staged-deployment-of-biventricular-micro-axial-flow-impella-catheters-bipella-is-associated-with-improved-survival-for-cardiogenic-shock-involving-biventricular-failure
#4
Navin Kapur, Catalina Breton, Ryan O'Kelly, Michele Esposito, Tobias Rheude, Andrew Mullin, Shiva Annamalai, Mark Grise, Michael Kiernan, Duc Thinh Pham, Mark Anderson, D Lynn Morris
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970284/tct-122-use-of-the-impella-5-0-circulatory-support-device-for-bridge-to-decision-during-acute-decompensation-of-advanced-heart-failure
#5
Shelley Hall, Nir Uriel, Sandra Carey, Michelle Edens, Michele Esposito, Ryan O'Kelly, Shiva Annamalai, Nima Aghili, Sirtaz Adatya, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970276/tct-114-comparing-hemodynamic-profiles-and-outcomes-in-cardiogenic-shock-requiring-va-ecmo-or-impella-for-circulatory-support
#6
Michele Esposito, Sudeep Kuchibhotla, David Zisa, Ryan O'Kelly, Shiva Annamalai, Adel Ghuloom, Leslie Lussier, Catalina Breton, Tobias Rheude, Andrew Mullin, Carey Kimmelstiel, Michael Kiernan, Amanda Vest, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969583/tct-23-contemporary-trends-in-utilization-of-mechanical-circulatory-support-in-patients-hospitalized-after-out-of-hospital-cardiac-arrest
#7
Nileshkumar Patel, Nish Patel, Gabriel Hernandez, Shilpkumar Arora, Apurva Badheka, Abhishek Deshmukh, Eduardo DeMarchena, Mauricio Cohen, Carlos Alfonso, Deepak Bhatt, Navin Kapur
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27865069/investing-in-our-future-update-on-the-scai-emerging-leader-mentorship-elm-program
#8
EDITORIAL
Dmitriy N Feldman, Herbert D Aronow, Rajesh V Swaminathan, J Dawn Abbott, Jennifer A Tremmel, Navin K Kapur, John P Breinholt, Anita W Asgar, Duane S Pinto, Thomas M Tu, Kenneth M Rosenfield, Srihari S Naidu
No abstract text is available yet for this article.
November 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27759925/small-acute-mechanical-circulatory-support-pumps-for-small-people
#9
Navin K Kapur, Michele Esposito
No abstract text is available yet for this article.
October 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27614169/endoglin-selectively-modulates-transient-receptor-potential-channel-expression-in-left-and-right-heart-failure
#10
Kevin J Morine, Vikram Paruchuri, Xiaoying Qiao, Mark Aronovitz, Gordon S Huggins, David DeNofrio, Michael S Kiernan, Richard H Karas, Navin K Kapur
INTRODUCTION: Transient receptor potential (TRP) channels are broadly expressed cation channels that mediate diverse physiological stimuli and include canonical (TRPC), melastatin (TRPM), and vanilloid (TRPV) subtypes. Recent studies have implicated a role for TRPC6 channels as an important component of signaling via the cytokine, transforming growth factor beta 1 (TGFβ1) in right (RV) or left ventricular (LV) failure. Endoglin (Eng) is a transmembrane glycoprotein that promotes TRPC6 expression and TGFβ1 activity...
November 2016: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/27503999/percutaneous-mechanical-circulatory-support-current-concepts-and-future-directions
#11
Natalia Briceno, Navin K Kapur, Divaka Perera
No abstract text is available yet for this article.
September 15, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27442859/distinct-effects-of-left-or-right-atrial-cannulation-on-left-ventricular-hemodynamics-in-a-swine-model-of-acute-myocardial-injury
#12
Michele L Esposito, Nimish Shah, Sam Dow, Sandra Kang, Vikram Paruchuri, Richard H Karas, Navin K Kapur
BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and the TandemHeart left ventricular (LV) assist device are increasingly employed as mechanical circulatory support devices during acute LV injury. METHODS: We examined the effects of right atrial to femoral artery (RA-FA; VA-ECMO) bypass versus left atrial to femoral artery (LA-FA; TandemHeart) bypass using a centrifugal pump (Cardiac Assist Inc) on LV hemodynamics in a swine model of acute LV injury...
July 20, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27397455/simulation-for-transthoracic-echocardiography-of-aortic-valve
#13
REVIEW
Navin C Nanda, K K Kapur, Poonam Malhotra Kapoor
Simulation allows interactive transthoracic echocardiography (TTE) learning using a virtual three-dimensional model of the heart and may aid in the acquisition of the cognitive and technical skills needed to perform TTE. The ability to link probe manipulation, cardiac anatomy, and echocardiographic images using a simulator has been shown to be an effective model for training anesthesiology residents in transesophageal echocardiography. A proposed alternative to real-time reality patient-based learning is simulation-based training that allows anesthesiologists to learn complex concepts and procedures, especially for specific structures such as aortic valve...
July 2016: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/27188188/biventricular-circulatory-support-using-2-axial-flow-catheters-for-cardiogenic-shock-without-the-need-for-surgical-vascular-access
#14
Nima Aghili, Yousef Bader, Amanda R Vest, Michael S Kiernan, Carey Kimmelstiel, David DeNofrio, Navin K Kapur
No abstract text is available yet for this article.
June 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/26999679/veno-arterial-extracorporeal-membrane-oxygenation-va-ecmo-fails-to-solve-the-haemodynamic-support-equation-in-cardiogenic-shock
#15
EDITORIAL
Navin K Kapur, David C Zisa
No abstract text is available yet for this article.
March 2016: EuroIntervention
https://www.readbyqxmd.com/read/26777757/preoperative-determinants-of-quality-of-life-and-functional-capacity-response-to-left-ventricular-assist-device-therapy
#16
Michael S Kiernan, Kartik S Sundareswaran, Duc Thinh Pham, Navin K Kapur, Naveen L Pereira, Martin Strueber, David J Farrar, David DeNofrio, Joseph G Rogers
BACKGROUND: Left ventricular assist devices (LVADs) improve survival, quality of life (QOL), and functional capacity (FC) among patients with end-stage heart failure. Few data are available regarding characteristics associated with QOL and FC response. METHODS AND RESULTS: Patients enrolled in the Heartmate II clinical trials that were alive with ongoing LVAD support at 6 months were included. QOL response criteria included scoring above the lowest quartile on either the Minnesota Living With Heart Failure Questionnaire or the Kansas City Cardiomyopathy Questionnaire...
October 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/26758053/percutaneous-mechanical-circulatory-support-for-cardiogenic-shock
#17
Kevin J Morine, Navin K Kapur
The use of percutaneous, non-durable mechanical circulatory support (MCS) for cardiogenic shock (CS) is growing; however, large, randomized clinical trials confirming benefit in this population do not exist. Guidelines and recommendations regarding optimal timing for MCS implementation, patient selection, device selection, and post-implantation management are beginning to emerge. A better understanding of (1) the distinct hemodynamic effects of each device option, (2) the need for early implementation of the appropriate device option for a particular clinical scenario, (3) the definition of non-salvageable CS to help clinicians know when to say "no" to non-durable MCS, and (4) best practices to monitor, wean, and optimize metabolic parameters while using non-durable MCS are required to continue improving clinical outcomes for patients with CS...
January 2016: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/26708637/usefulness-of-intra-aortic-balloon-pump-counterpulsation
#18
REVIEW
Lokien X van Nunen, Marko Noc, Navin K Kapur, Manesh R Patel, Divaka Perera, Nico H J Pijls
Intra-aortic balloon pump (IABP) counterpulsation is the most widely used mechanical circulatory support device because of its ease of use, low complication rate, and fast manner of insertion. Its benefit is still subject of debate, and a considerable gap exists between guidelines and clinical practice. Retrospective nonrandomized studies and animal experiments show benefits of IABP therapy. However, recent large randomized trials do not show benefit of IABP therapy, which has led to a downgrading in the guidelines...
February 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/26681124/benefits-of-a-novel-percutaneous-ventricular-assist-device-for-right-heart-failure-the-prospective-recover-right-study-of-the-impella-rp-device
#19
MULTICENTER STUDY
Mark B Anderson, James Goldstein, Carmelo Milano, Lynn D Morris, Robert L Kormos, Jay Bhama, Navin K Kapur, Aditya Bansal, Jose Garcia, Joshua N Baker, Scott Silvestry, William L Holman, Pamela S Douglas, William O'Neill
BACKGROUND: Right ventricular failure (RVF) increases morbidity and mortality. The RECOVER RIGHT study evaluated the safety and efficacy of a novel percutaneous right ventricular assist device, the Impella RP (Abiomed, Danvers, MA), in a prospective, multicenter trial. METHODS: Thirty patients with RVF refractory to medical treatment received the Impella RP device at 15 United States institutions. The study population included 2 cohorts: 18 patients with RVF after left ventricular assist device (LVAD) implantation (Cohort A) and 12 patients with RVF after cardiotomy or myocardial infarction (Cohort B)...
December 2015: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/26667393/circulating-multimarker-profile-of-patients-with-symptomatic-heart-failure-supports-enhanced-fibrotic-degradation-and-decreased-angiogenesis
#20
Kevin J Morine, Vikram Paruchuri, Xiaoying Qiao, Najwa Mohammad, Adam Mcgraw, Adil Yunis, Iris Jaffe, Navin K Kapur
BACKGROUND: Heart failure (HF) involves myocardial fibrosis and dysregulated angiogenesis. OBJECTIVE: We explored whether biomarkers of fibrosis and angiogenesis correlate with HF severity. METHODS: Biomarkers of fibrosis [procollagen types I and III (PIP and P3NP), carboxyterminal-telopeptide of type I collagen (ICTP), matrix metalloproteases (MMP2 and MMP9), tissue inhibitor of MMP1 (TIMP1)]; and angiogenesis [placental growth factor (PGF), vascular endothelial growth factor (VEGF), soluble Fms-like tyrosine kinase-1 (sFlt1)] were measured in 52 HF patients and 19 controls...
2016: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
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