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Nick Justice

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https://www.readbyqxmd.com/read/27618447/trans-ancestry-meta-analyses-identify-rare-and-common-variants-associated-with-blood-pressure-and-hypertension
#1
Praveen Surendran, Fotios Drenos, Robin Young, Helen Warren, James P Cook, Alisa K Manning, Niels Grarup, Xueling Sim, Daniel R Barnes, Kate Witkowska, James R Staley, Vinicius Tragante, Taru Tukiainen, Hanieh Yaghootkar, Nicholas Masca, Daniel F Freitag, Teresa Ferreira, Olga Giannakopoulou, Andrew Tinker, Magdalena Harakalova, Evelin Mihailov, Chunyu Liu, Aldi T Kraja, Sune Fallgaard Nielsen, Asif Rasheed, Maria Samuel, Wei Zhao, Lori L Bonnycastle, Anne U Jackson, Narisu Narisu, Amy J Swift, Lorraine Southam, Jonathan Marten, Jeroen R Huyghe, Alena Stančáková, Cristiano Fava, Therese Ohlsson, Angela Matchan, Kathleen E Stirrups, Jette Bork-Jensen, Anette P Gjesing, Jukka Kontto, Markus Perola, Susan Shaw-Hawkins, Aki S Havulinna, He Zhang, Louise A Donnelly, Christopher J Groves, N William Rayner, Matt J Neville, Neil R Robertson, Andrianos M Yiorkas, Karl-Heinz Herzig, Eero Kajantie, Weihua Zhang, Sara M Willems, Lars Lannfelt, Giovanni Malerba, Nicole Soranzo, Elisabetta Trabetti, Niek Verweij, Evangelos Evangelou, Alireza Moayyeri, Anne-Claire Vergnaud, Christopher P Nelson, Alaitz Poveda, Tibor V Varga, Muriel Caslake, Anton J M de Craen, Stella Trompet, Jian'an Luan, Robert A Scott, Sarah E Harris, David C M Liewald, Riccardo Marioni, Cristina Menni, Aliki-Eleni Farmaki, Göran Hallmans, Frida Renström, Jennifer E Huffman, Maija Hassinen, Stephen Burgess, Ramachandran S Vasan, Janine F Felix, Maria Uria-Nickelsen, Anders Malarstig, Dermot F Reilly, Maarten Hoek, Thomas F Vogt, Honghuang Lin, Wolfgang Lieb, Matthew Traylor, Hugh S Markus, Heather M Highland, Anne E Justice, Eirini Marouli, Jaana Lindström, Matti Uusitupa, Pirjo Komulainen, Timo A Lakka, Rainer Rauramaa, Ozren Polasek, Igor Rudan, Olov Rolandsson, Paul W Franks, George Dedoussis, Timothy D Spector, Pekka Jousilahti, Satu Männistö, Ian J Deary, John M Starr, Claudia Langenberg, Nick J Wareham, Morris J Brown, Anna F Dominiczak, John M Connell, J Wouter Jukema, Naveed Sattar, Ian Ford, Chris J Packard, Tõnu Esko, Reedik Mägi, Andres Metspalu, Rudolf A de Boer, Peter van der Meer, Pim van der Harst, Giovanni Gambaro, Erik Ingelsson, Lars Lind, Paul I W de Bakker, Mattijs E Numans, Ivan Brandslund, Cramer Christensen, Eva R B Petersen, Eeva Korpi-Hyövälti, Heikki Oksa, John C Chambers, Jaspal S Kooner, Alexandra I F Blakemore, Steve Franks, Marjo-Riitta Jarvelin, Lise L Husemoen, Allan Linneberg, Tea Skaaby, Betina Thuesen, Fredrik Karpe, Jaakko Tuomilehto, Alex S F Doney, Andrew D Morris, Colin N A Palmer, Oddgeir Lingaas Holmen, Kristian Hveem, Cristen J Willer, Tiinamaija Tuomi, Leif Groop, AnneMari Käräjämäki, Aarno Palotie, Samuli Ripatti, Veikko Salomaa, Dewan S Alam, Abdulla Al Shafi Majumder, Emanuele Di Angelantonio, Rajiv Chowdhury, Mark I McCarthy, Neil Poulter, Alice V Stanton, Peter Sever, Philippe Amouyel, Dominique Arveiler, Stefan Blankenberg, Jean Ferrières, Frank Kee, Kari Kuulasmaa, Martina Müller-Nurasyid, Giovanni Veronesi, Jarmo Virtamo, Panos Deloukas, Paul Elliott, Eleftheria Zeggini, Sekar Kathiresan, Olle Melander, Johanna Kuusisto, Markku Laakso, Sandosh Padmanabhan, David J Porteous, Caroline Hayward, Generation Scotland, Francis S Collins, Karen L Mohlke, Torben Hansen, Oluf Pedersen, Michael Boehnke, Heather M Stringham, Philippe Frossard, Christopher Newton-Cheh, Martin D Tobin, Børge Grønne Nordestgaard, Mark J Caulfield, Anubha Mahajan, Andrew P Morris, Maciej Tomaszewski, Nilesh J Samani, Danish Saleheen, Folkert W Asselbergs, Cecilia M Lindgren, John Danesh, Louise V Wain, Adam S Butterworth, Joanna M M Howson, Patricia B Munroe
High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to 192,763 individuals and used ∼155,063 samples for independent replication. We identified 30 new blood pressure- or hypertension-associated genetic regions in the general population, including 3 rare missense variants in RBM47, COL21A1 and RRAS with larger effects (>1...
October 2016: Nature Genetics
https://www.readbyqxmd.com/read/27044171/patient-mobility-in-times-of-austerity-a-legal-and-policy-analysis-of-the-petru-case
#2
Markus Frischhut, Nick Fahy
The case-law of the Court of Justice (ECJ) on patient mobility was recently challenged by a ruling that a patient could go to Germany for treatment when facilities in Romanian hospitals were inadequate. Given the reported impact of austerity measures in the field of health care this raises the question; what is the impact of the ECJ's ruling on how Member States can manage expenditure and limit outflows of patients and how should such measures be legally evaluated? The objective of this article is to analyse potential impact on health systems in the context of increasing pressure on public financing for health...
March 2016: European Journal of Health Law
https://www.readbyqxmd.com/read/26771169/improving-outcomes-for-people-in-mental-health-crisis-a-rapid-synthesis-of-the-evidence-for-available-models-of-care
#3
REVIEW
Fiona Paton, Kath Wright, Nigel Ayre, Ceri Dare, Sonia Johnson, Brynmor Lloyd-Evans, Alan Simpson, Martin Webber, Nick Meader
BACKGROUND: Crisis Concordat was established to improve outcomes for people experiencing a mental health crisis. The Crisis Concordat sets out four stages of the crisis care pathway: (1) access to support before crisis point; (2) urgent and emergency access to crisis care; (3) quality treatment and care in crisis; and (4) promoting recovery. OBJECTIVES: To evaluate the clinical effectiveness and cost-effectiveness of the models of care for improving outcomes at each stage of the care pathway...
January 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/25004034/scotland-faces-questions-over-restructuring-health-workforce
#4
Nick Triggle
The past few years have been a period of flux for nurses working to improve the health of children in Scotland. But 2013 is likely to go down as a watershed. Indeed, you could say it was the year that health visiting and school nursing was reborn.
July 2014: Nursing Children and Young People
https://www.readbyqxmd.com/read/24559151/has-the-sanctity-of-life-law-gone-too-far-analysis-of-the-sanctity-of-life-doctrine-and-english-case-law-shows-that-the-sanctity-of-life-law-has-not-gone-too-far
#5
REVIEW
Abdul-Rasheed Rabiu, Kapil Sugand
The medical profession consistently strives to uphold patient empowerment, equality and safety. It is ironic that now, at a time where advances in technology and knowledge have given us an increased capacity to preserve and prolong life, we find ourselves increasingly asking questions about the value of the lives we are saving. A recent editorial by Professor Raanan Gillon questions the emphasis that English law places on the sanctity of life doctrine. In what was described by Reverend Nick Donnelly as a "manifesto for killing patients", Professor Gillon argues that the sanctity of life law has gone too far because of its disregard for distributive justice and an incompetent person's previously declared autonomy...
2014: Philosophy, Ethics, and Humanities in Medicine: PEHM
https://www.readbyqxmd.com/read/23910844/a-clean-bill-of-health-the-efficacy-of-an-nhs-commissioned-outsourced-police-custody-healthcare-service
#6
Nick de Viggiani
Police custody healthcare services for detainees in the UK are most commonly outsourced to independent healthcare providers who employ custody nurses and forensic physicians to deliver forensic healthcare services. A pilot was introduced in 2008 by the Department of Health to explore the efficacy of commissioning custody healthcare via the NHS, in the wake of the 2005-2006 shift of prison healthcare to the NHS. The objective was to improve quality and accountability through NHS commissioning and the introduction of NHS governance to the management and delivery of custody healthcare...
August 2013: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/23881873/cost-implications-of-treatment-non-completion-in-a-forensic-personality-disorder-service
#7
Christopher James Sampson, Marilyn James, Nick Huband, Steve Geelan, Mary McMurran
BACKGROUND: A high proportion of individuals admitted to specialist secure hospital services for treatment of personality disorder do not complete treatment. Non-completion has been associated with poorer treatment outcomes and increased rates of recidivism and hospital readmission, when compared with individuals who do complete treatment or who do not receive treatment at all. AIMS: In this study, we sought to determine the economic consequences of non-completion of treatment, using case study data from a secure hospital sample...
December 2013: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/23626737/the-roles-of-dehumanization-and-moral-outrage-in-retributive-justice
#8
Brock Bastian, Thomas F Denson, Nick Haslam
When innocents are intentionally harmed, people are motivated to see that offenders get their "just deserts". The severity of the punishment they seek is driven by the perceived magnitude of the harm and moral outrage. The present research extended this model of retributive justice by incorporating the role of offender dehumanization. In three experiments relying on survey methodology in Australia and the United States, participants read about different crimes that varied by type (child molestation, violent, or white collar - Studies 1 and 2) or severity (Study 3)...
2013: PloS One
https://www.readbyqxmd.com/read/23235646/psychological-interventions-for-adults-who-have-sexually-offended-or-are-at-risk-of-offending
#9
REVIEW
Jane A Dennis, Omer Khan, Michael Ferriter, Nick Huband, Melanie J Powney, Conor Duggan
BACKGROUND: Sexual offending is a legal construct that overlaps, but is not entirely congruent with, clinical constructs of disorders of sexual preference. Sexual offending is both a social and a public health issue. Victim surveys illustrate high incidence and prevalence levels, and it is commonly accepted that there is considerable hidden sexual victimisation. There are significant levels of psychiatric morbidity in survivors of sexual offences.Psychological interventions are generally based on behavioural or psychodynamic theories...
2012: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/23054079/in-vivo-knockdown-of-intersectin-1s-alters-endothelial-cell-phenotype-and-causes-microvascular-remodeling-in-the-mouse-lungs
#10
Cristina Bardita, Dan Predescu, Matthew J Justice, Irina Petrache, Sanda Predescu
Intersectin-1s (ITSN-1s) is a general endocytic protein involved in regulating lung vascular permeability and endothelial cells (ECs) survival, via MEK/Erk1/2(MAPK) signaling. To investigate the in vivo effects of ITSN-1s deficiency and the resulting ECs apoptosis on pulmonary vasculature and lung homeostasis, we used an ITSN-1s knocked-down (KD(ITSN)) mouse generated by repeated delivery of a specific siRNA targeting ITSN-1 gene (siRNA(ITSN)). Biochemical and histological analyses as well as electron microscopy (EM) revealed that acute KD(ITSN) [3-days (3d) post-siRNA(ITSN) treatment] inhibited Erk1/2(MAPK) pro-survival signaling, causing significant ECs apoptosis and lung injury; at 10d of KD(ITSN), caspase-3 activation was at peak, terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL)-positive ECs showed 3...
January 2013: Apoptosis: An International Journal on Programmed Cell Death
https://www.readbyqxmd.com/read/22936716/is-organizational-justice-associated-with-clinical-performance-in-the-care-for-patients-with-diabetes-in-primary-care-evidence-from-the-improving-quality-of-care-in-diabetes-study
#11
MULTICENTER STUDY
Marko Elovainio, Nick Steen, Justin Presseau, Jill Francis, Susan Hrisos, Gillian Hawthorne, Marie Johnston, Elaine Stamp, Margaret Hunter, Jeremy M Grimshaw, Martin P Eccles
BACKGROUND: Type 2 diabetes is an increasingly prevalent illness, and there is considerable variation in the quality of care provided to patients with diabetes in primary care. OBJECTIVES: The aim of this study was to explore whether organizational justice and organizational citizenship behaviour are associated with the behaviours of clinical staff when providing care for patients with diabetes. METHODS: The data were from an ongoing prospective multicenter study, the 'improving Quality of care in Diabetes' (iQuaD) study...
February 2013: Family Practice
https://www.readbyqxmd.com/read/22895952/psychological-therapies-for-people-with-borderline-personality-disorder
#12
REVIEW
Jutta M Stoffers, Birgit A Völlm, Gerta Rücker, Antje Timmer, Nick Huband, Klaus Lieb
BACKGROUND: Psychotherapy is regarded as the first-line treatment for people with borderline personality disorder. In recent years, several disorder-specific interventions have been developed. This is an update of a review published in the Cochrane Database of Systematic Reviews in 2006. OBJECTIVES: To assess the effects of psychological interventions for borderline personality disorder (BPD). SEARCH METHODS: We searched the following databases: CENTRAL 2010(3), MEDLINE (1950 to October 2010), EMBASE (1980 to 2010, week 39), ASSIA (1987 to November 2010), BIOSIS (1985 to October 2010), CINAHL (1982 to October 2010), Dissertation Abstracts International (31 January 2011), National Criminal Justice Reference Service Abstracts (15 October 2010), PsycINFO (1872 to October Week 1 2010), Science Citation Index (1970 to 10 October 2010), Social Science Citation Index (1970 to 10 October 2010), Sociological Abstracts (1963 to October 2010), ZETOC (15 October 2010) and the metaRegister of Controlled Trials (15 October 2010)...
August 15, 2012: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/22553044/screening-for-alcohol-use-in-criminal-justice-settings-an-exploratory-study
#13
RANDOMIZED CONTROLLED TRIAL
Simon Coulton, Dorothy Newbury-Birch, Paul Cassidy, Veronica Dale, Paolo Deluca, Eilish Gilvarry, Christine Godfrey, Nick Heather, Eileen Kaner, Adenekan Oyefeso, Steve Parrott, Tom Phillips, Jonathan Shepherd, Colin Drummond
AIMS: To examine the feasibility and acceptability of alcohol screening and delivery of brief interventions within criminal justice settings. METHODS: A quantitative survey of those aged 18 or over in English criminal justice settings (three custody suites within police stations, three prisons and three probation offices). MEASUREMENTS: The Fast Alcohol Screening Test (FAST) and a modified version of the Single Alcohol Screening Question (M-SASQ) were compared with the Alcohol Use Disorders Identification Test (AUDIT) as the 'gold standard'...
July 2012: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/22415559/music-making-for-health-well-being-and-behaviour-change-in-youth-justice-settings-a-systematic-review
#14
Norma Daykin, Nick de Viggiani, Paul Pilkington, Yvonne Moriarty
Youth justice is an important public health issue. There is growing recognition of the need to adopt effective, evidence-based strategies for working with young offenders. Music interventions may be particularly well suited to addressing risk factors in young people and reducing juvenile crime. This systematic review of international research seeks to contribute to the evidence base on the impact of music making on the health, well-being and behaviour of young offenders and those considered at risk of offending...
June 2013: Health Promotion International
https://www.readbyqxmd.com/read/21443390/blame-and-accountability-1-understanding-blame-and-blame-pathologies
#15
Nick O'Connor, Beth Kotze, Murray Wright
OBJECTIVE: In this first paper the role and dynamics of blame in the context of medical critical incidents is examined. Blame pathologies are described and the complex nature of medical adverse events and the environment are explored. METHODS: The literature is examined and a case scenario explored. RESULTS: Evidence regarding effects of a 'blame culture' on clinicians and organizations is presented. In an accompanying second paper the place of accountability in relation to clinicians and health organizations is elucidated...
April 2011: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/21271432/promoting-strengths-prevention-empowerment-and-community-change-through-organizational-development-lessons-for-research-theory-and-practice
#16
Scotney D Evans, Ora Prilleltensky, Adrine McKenzie, Isaac Prilleltensky, Debbie Nogueras, Corinne Huggins, Nick Mescia
SPEC Learning and Changing by Doing is a three-year, action research, and organizational change project designed to ultimately promote social justice and well-being in the community. SPEC is an acronym that stands for Strengths, Prevention, Empowerment, and Community Change. The project consists of five organizations tackling internal organizational change in order to better promote justice and well-being in their respective constituencies. In this article we present a formative evaluation of this multicase study of organizational change in human services...
2011: Journal of Prevention & Intervention in the Community
https://www.readbyqxmd.com/read/20853959/comparing-perceived-injustices-from-supervisors-and-romantic-partners-as-predictors-of-aggression
#17
Kathryne E Dupré, Julian Barling, Nick Turner, Chris B Stride
To examine the predictive effects of perceived injustice in two different interpersonal relationships (i.e., working relationship with a supervisor, romantic relationship with a partner) on aggression enacted in those relationships, we computed a series of multilevel regressions on 62 heterosexual couples with all 124 partners employed part-time and working for different supervisors. Higher levels of perceived supervisor injustice predicted higher supervisor-directed aggression, whereas higher levels of perceived partner injustice predicted lower supervisor-directed aggression...
October 2010: Journal of Occupational Health Psychology
https://www.readbyqxmd.com/read/20687091/pharmacological-interventions-for-antisocial-personality-disorder
#18
REVIEW
Najat Khalifa, Conor Duggan, Jutta Stoffers, Nick Huband, Birgit A Völlm, Michael Ferriter, Klaus Lieb
BACKGROUND: Antisocial personality disorder (AsPD) is associated with a wide range of disturbance including persistent rule-breaking, criminality, substance misuse, unemployment, homelessness and relationship difficulties. OBJECTIVES: To evaluate the potential beneficial and adverse effects of pharmacological interventions for people with AsPD. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2009, Issue 3), MEDLINE (1950 to September 2009), EMBASE (1980 to 2009, week 37), CINAHL (1982 to September 2009), PsycINFO (1872 to September 2009) , ASSIA (1987 to September 2009) , BIOSIS (1985 to September 2009), COPAC (September 2009), National Criminal Justice Reference Service Abstracts (1970 to July 2008), Sociological Abstracts (1963 to September 2009), ISI-Proceedings (1981 to September 2009), Science Citation Index (1981 to September 2009), Social Science Citation Index (1981 to September 2009), SIGLE (1980 to April 2006), Dissertation Abstracts (September 2009), ZETOC (September 2009) and the metaRegister of Controlled Trials (September 2009)...
2010: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/20411315/contextual-biases-in-the-interpretation-of-auditory-evidence
#19
Nick D Lange, Rick P Thomas, Jason Dana, Robyn M Dawes
Noisy recordings of dialogue often serve as evidence in criminal proceedings. The present article explores the ability of two types of contextual information, currently present in the legal system, to bias subjective interpretations of such evidence. The present experiments demonstrate that the general context of the legal system and the presence of transcripts of the recorded speech are both able to bias interpretations of degraded & benign recordings into interpretable & incriminating. Furthermore we demonstrate a curse of knowledge whereby people become miscalibrated to the true quality of degraded recordings when provided transcripts...
June 2011: Law and Human Behavior
https://www.readbyqxmd.com/read/19937923/bootstrapping-persistence-risk-indicators-for-juveniles-who-sexually-offend
#20
COMPARATIVE STUDY
Raymond A Knight, Scott T Ronis, Barry Zakireh
This research was supported by research grants MH54263-01 from the National Institute of Mental Health and 94-IJ-CX-0049 from the National Institute of Justice. The authors wish to express their deep appreciation to the staff in the numerous institutions at which we have tested for their considerable commitment of time and energy to our research program. We also thank all the offenders who participated in our research. Special thanks are due to David Cerce and Alison Martino for coordinating the coding of files and organizing all of our data, to Nick Fadden and Karen Fadden for help in coordinating and collecting the Minnesota data, and to Karen Locke for her programming and data processing skills...
November 2009: Behavioral Sciences & the Law
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