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https://www.readbyqxmd.com/read/28944226/a-prospective-analysis-of-risk-factors-for-pediatric-burn-mortality-at-a-tertiary-burn-center-in-north-india
#1
Amol Dhopte, Rahul Bamal, Vinay Kumar Tiwari
BACKGROUND: None of the available mortality predicting models in pediatric burns precisely predicts outcomes in every population. Mortality rates as well as their risk factors vary with regions and among different centers within the regions. The aim of this study was to identify socio-demographic and clinical risk factors for mortality in pediatric burns in an effort to decrease the mortality in these patients. METHODS: A prospective analytical study was conducted in patients up to the age of 18 years admitted for burn injuries in a tertiary care burn center in India from January to December 2014...
2017: Burns and trauma
https://www.readbyqxmd.com/read/28943637/cell-death-a-better-way-to-die
#2
Anna Dart
No abstract text is available yet for this article.
September 25, 2017: Nature Reviews. Cancer
https://www.readbyqxmd.com/read/28943415/management-of-blood-blister-like-aneurysms-of-the-internal-carotid-artery-lessons-learned-from-direct-clipping-in-22-cases
#3
Zheng Liu, Shangming Zhang, Shousen Wang, Qizuan Chen
OBJECTIVE: To present a case series of blood blister-like aneurysms (BBAs) of the internal carotid artery (ICA) and an assessment of diagnosis and treatment options, attempting to identify surgical or endovascular management of BBAs with a low complication rate and a functional outcome. METHODS: A retrospective analysis including diagnosis and treatment options of BBAs of the ICA was performed of patients treated for BBAs at Fuzhou General Hospital from January 2008 to September 2016...
September 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28943158/dynamics-of-nutritional-competence-in-the-last-year-before-death-in-a-large-cohort-of-us-hemodialysis-patients
#4
Xiaoling Ye, Marijke J E Dekker, Franklin W Maddux, Peter Kotanko, Constantijn J A M Konings, Jochen G Raimann, Frank M van der Sande, Len A Usvyat, Jeroen P Kooman, Stephan Thijssen
OBJECTIVES: Recently, a new Nutritional Competence Score (NCS) has been shown to associate with hospitalization and outcome in hemodialysis patients. The aim of this study was to investigate the dynamics, the individual components, and the impact of hospitalizations of this score's trajectory in the year before death. In addition, we investigated whether dynamics in the NCS add additional independent prognostic value over a single cross-sectional assessment. DESIGN: We included all Fresenius Medical Care North America patients who initiated hemodialysis between January 1, 2006, and December 31, 2011 with data on all 5 NCS components (serum albumin, creatinine, phosphate, equilibrated normalized protein catabolic rate, and interdialytic weight gain) in at least 1 month...
September 21, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28943109/-prevalence-and-spectrum-of-diseases-that-predispose-to-sudden-cardiac-death-in-mexican-children-a-sample-obtained-from-the-children-s-hospital-of-mexico-federico-gomez
#5
Karla Sarahí Cano-Hernández, Santiago Nava-Townsend, Adriana Sánchez-Boiso, Rocío Sánchez-Urbina, Alejandra Contreras-Ramos, Julio Roberto Erdmenger-Orellana, Tania Tamayo-Espinosa, Rosario Becerra-Becerra, Begoña Segura-Stanford, Liborio Solano-Fiesco, Norma Alicia Balderrábano-Saucedo
OBJECTIVE: To determine the prevalence and spectrum of diseases that predispose to sudden cardiac death in Mexican children and to identify the main early signs and symptoms that can enable the health personnel to suspect about these diseases and to refer the patients to a tertiary hospital in a timely manner. METHODS: Incidence, prevalence and prevalence of period as well as early symptoms, clinical data and follow-up are described in all children found with diseases that predispose to sudden cardiac death at The Children's Hospital of Mexico...
September 21, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28942746/rapid-autopsy-of-a-patient-with-recurrent-anaplastic-ependymoma
#6
Katharine Rae Lange, Cheryl Fischer, Prajwal Rajappa, Scott Connors, David Pisapia, Jeffrey P Greenfield, Himisha Beltran, Mark Rubin, Juan Miguel Mosquera, Yasmin Khakoo
OBJECTIVE: Our aim was to outline a procedure for obtaining a rapid autopsy in order to collect high-quality postmortem tissue for genomic analysis. METHODS: This report details a bi-institutional collaborative effort to coordinate a rapid autopsy for a pediatric patient who had died at home. We discuss the scientific rationale for offering a rapid autopsy to caregivers of pediatric patients as well as parental perspectives on broaching the subject of autopsy. We then review the logistics and coordination involved with planning a rapid autopsy and the sequence of events needed to maximize tissue quality...
September 25, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28942441/the-clinical-characteristics-and-prognostic-analysis-of-status-epilepticus-in-northeast-china
#7
Lichao Sun, Chuntao Han, Weihong Lin
OBJECTIVE: Status epilepticus (SE) is a neurological emergency that may cause severe neurological deficiency and even death. The aim of this study was to analyze the clinical characteristics and prognosis of SE in northeast China. Additionally, the etiology and classification are discussed. MATERIALS AND METHODS: We retrospectively collected the clinical profiles of patients diagnosed with SE in the Epilepsy Center of Jilin University between January 2011 and May 2015...
September 22, 2017: European Neurology
https://www.readbyqxmd.com/read/28941964/unmet-palliative-care-needs-among-patients-with-end-stage-kidney-disease-a-national-registry-study-about-the-last-week-of-life
#8
Lena Axelsson, Anette Alvariza, Jenny Lindberg, Joakim Öhlén, Cecilia Håkanson, Helene Reimertz, Carl-Johan Fürst, Kristofer Årestedt
CONTEXT: End-stage kidney disease (ESKD) is characterized by high physical and psychological burden and therefore, more knowledge about the palliative care provided close to death is needed. OBJECTIVES: To describe symptom prevalence, relief and management during the last week of life, as well as end-of-life communication, in patients with ESKD. METHODS: This study was based on data from the Swedish Register of Palliative Care. Patients aged 18 or older who died from a chronic kidney disease, with or without dialysis treatment (ICD-10-SE; N18...
September 20, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28941852/predictors-of-adverse-outcome-in-patients-of-tuberculous-meningitis-in-a-multi-centric-study-from-india
#9
Renu Gupta, Suman Kushwaha, Rajeev Thakur, Nupur Jalan, Pumanshi Rawat, Piyush Gupta, Amitesh Aggarwal, Meena Gupta, Vikas Manchanda
INTRODUCTION: This study aimed to investigate the factors which may predict mortality and neurological disability at one year follow up in patients of tuberculous meningitis (TBM) in India. METHODOLOGY: Patients with TBM were prospectively enrolled from July 2012 to September 2014 from four tertiary care hospitals of Delhi. The demographic characteristics, clinical features and laboratory findings were collected and patients were followed up till 1 year. These were analyzed by univariate and multivariate multinomial logistic regression analysis to identify predictors of adverse patient outcome at 1 year follow up...
October 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28941581/use-of-frailty-to-predict-survival-in-elderly-patients-with-early-stage-non-small-cell-lung-cancer-treated-with-stereotactic-body-radiation-therapy
#10
Idalid Franco, Yu-Hui Chen, Fallon Chipidza, Vishesh Agrawal, John Romano, Elizabeth Baldini, Aileen Chen, Yolonda Colson, Ying Hou, David Kozono, Jon Wee, Raymond Mak
OBJECTIVES: Frailty has been shown to increase morbidity and mortality independent of age, but studies are lacking in radiation oncology. This study evaluates a modified frailty index (mFI) in predicting overall survival (OS) and non-cancer death for Stage I/II [N0M0] Non-Small-Cell Lung Cancer (NSCLC) patients treated with Stereotactic Body Radiation Therapy (SBRT). MATERIALS AND METHODS: Medical records for all patients with Stage I/II NSCLC treated at our institution with SBRT from 2009 to 2014 were reviewed...
September 20, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28941542/end-of-life-and-bereavement-care-in-pediatric-intensive-care-units
#11
REVIEW
Markita L Suttle, Tammara L Jenkins, Robert F Tamburro
Most childhood deaths in the United States occur in hospitals. Pediatric intensive care clinicians must anticipate and effectively treat dying children's pain and suffering and support the psychosocial and spiritual needs of families. These actions may help family members adjust to their loss, particularly bereaved parents who often experience reduced mental and physical health. Candid and compassionate communication is paramount to successful end-of-life (EOL) care as is creating an environment that fosters meaningful family interaction...
October 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28941298/symptom-management-and-psychological-support-for-families-are-the-cornerstones-of-end-of-life-care-for-children-with-spinal-muscular-atrophy-type-1
#12
Chiara Di Pede, Caterina Agosto, Valentina De Tommasi, Alessandra De Gregorio, Franca Benini
AIM: This study described end-of-life care for children affected by spinal muscular atrophy type 1 (SMA1), which is characterised by progressive muscle weakness and develops in the first six months of life. METHODS: We retrospectively analysed 17 children (13 boys) who attended the University of Padua's paediatric palliative care centre in Italy from March 2000 to March 2015. All the children received supportive care without proactive respiratory intervention to prolong survival...
September 23, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28940999/hearts-transplanted-after-circulatory-death-in-children-analysis-of-the-international-society-for-heart-and-lung-transplantation-registry
#13
Jake A Kleinmahon, Sonali S Patel, Scott R Auerbach, Joseph Rossano, Melanie D Everitt
We aimed to describe worldwide DCD HT experience in children using the International Society for Heart and Lung Transplantation Registry. The Registry was queried for primary HT performed in children (2005-2014). Kaplan-Meier analysis was used to assess survival for recipients grouped by DCD or DBD hearts. Recipient characteristics were compared between DCD and DBD and between survivors and non-survivors of DCD HT. Among 3877 pediatric HT performed, 21 (0.5%) were DCD. DCD 1-year survival was 61% vs 91% DBD, P < ...
September 21, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28940952/real-world-uptake-safety-profile-and-outcomes-of-docetaxel-in-newly-diagnosed-metastatic-prostate-cancer
#14
Robert Rulach, Stephen McKay, Sam Neilson, Lillian White, Jan Wallace, Ross Carruthers, Carolynn Lamb, Almudena Cascales, Husam Marashi, Hilary Glen, Balaji Venugopal, Azmat Sadoyze, Norma Sidek, J Martin Russell, Abdulla Alhasso, David Dodds, Jennifer Laskey, Robert J Jones, Nicholas MacLeod
OBJECTIVES: To investigate the uptake, safety and efficacy of docetaxel chemotherapy in hormone-naïve metastatic prostate cancer (mPC) in the first year of use outside of a clinical trial. SUBJECTS/PATIENTS AND METHODS: Patients in the West of Scotland Cancer Network (WoSCAN) with newly diagnosed mPC were identified from the regional multidisciplinary team (MDT) meetings and their treatment details were collected from electronic patient records. The rate of febrile neutropenia, hospitalisations, time to progression and overall survival were compared between those patients who received docetaxel and androgen deprivation therapy (ADT), or ADT alone using survival analysis...
September 20, 2017: BJU International
https://www.readbyqxmd.com/read/28940704/hypermetabolism-is-a-deleterious-prognostic-factor-in-patients-with-amyotrophic-lateral-sclerosis
#15
Pierre Jésus, Philippe Fayemendy, Marie Nicol, Géraldine Lautrette, Huguette Sourisseau, Pierre-Marie Preux, Jean-Claude Desport, Benoit Marin, Philippe Couratier
The aim of this study was to investigate in ALS patients in order to determine their nutritional, neurological and respiratory parameters and their survival according to the metabolic level. METHODS: Nutritional assessment included resting energy expenditure (REE) measured by indirect calorimetry (hypermetabolism if REE variation [ΔREE] > 10%) and fat mass (FM) using impedancemetry. Neurological assessment included ALSFRS-R score. Survival analysis used the Kaplan-Meier method and the multivariate Cox model...
September 20, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28940542/metal-railing-fences-and-accidental-death
#16
Karen J Heath, Allan D Cala, Roger W Byard
Two cases of accidental deaths caused by the sharp ends of fence or gate posts are reported. Case 1: A 47-year-old man was found hanging by his ankle in an inverted position on fencing. He had attempted a shortcut to a railway platform by climbing over a metal rail fence. He had slipped and been impaled through his ankle by the sharp end of the fence post, resulting in death from positional asphyxia. Case 2: An 18-year-old male slipped while climbing over a gate and died after being impaled on a spear tip finial, which had lacerated his external iliac vein...
September 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28940541/ebstein-anomaly-and-sudden-childhood-death
#17
Amanda Freeman, Roger W Byard
A 13-year-old girl is reported who died suddenly and unexpectedly in her sleep from previously undiagnosed Ebstein anomaly. At autopsy, there was dilatation of the right atrium with marked dilatation of the right auricle and apical displacement of the tricuspid valve into the right ventricular cavity with atrialization of the upper portion of the right ventricle. There were also prominent dysplastic changes in both the septal and posterior leaflets of the tricuspid valve with thickening of the valve and fusion of leaflets to the wall of the ventricle...
September 20, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28940342/physician-assisted-death-and-severe-treatment-resistant-depression
#18
Bonnie Steinbock
Should people suffering from untreatable psychiatric conditions be eligible for physician-assisted death? This is possible in Belgium and the Netherlands, where PAD for psychiatric conditions is permitted, though rare, so long as the criteria of due care are met. Those opposed to all instances of PAD point to Belgium and the Netherlands as a dark warning that once PAD is legalized, restricting it will prove impossible because safeguards, such as the requirement that a patient be terminally ill, will inevitably be eroded or discarded...
September 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28940226/the-effect-of-leprotic-infection-on-the-risk-of-death-in-medieval-rural-denmark
#19
K Saige Kelmelis, Michael Holton Price, Jim Wood
INTRODUCTION: Paleopathological studies of leprosy in Danish skeletal collections show that many individuals suffered from this stigmatized disease during the Middle Ages. This study examines the risk of death associated with leprotic infection in individuals from the Danish rural cemetery of Øm Kloster (AD 1172-1536). Specifically, we modeled the influence of leprotic infection on age-specific mortality accounting also for sex and social status (lay person / monastic). MATERIALS AND METHODS: The sample consisted of 311 adult individuals from the Øm Kloster skeletal collection housed at the Institute of Forensic Medicine, University of Southern Denmark (ADBOU)...
September 22, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28939940/non-motor-multiple-system-atrophy-associated-with-sudden-death-pathological-observations-of-autonomic-nuclei
#20
Yuichi Riku, Hirohisa Watanabe, Maya Mimuro, Yasushi Iwasaki, Mizuki Ito, Masahisa Katsuno, Gen Sobue, Mari Yoshida
Multiple system atrophy (MSA) manifests as a combination of dysautonomia and motor symptoms/signs. However, rare cases presenting with autonomic failures in absence of motor symptoms/signs until their deaths have been reported and are referred to as non-motor MSA. To clarify pathological findings underlying non-motor MSA patients, we analyzed consecutively autopsied 161 patients with MSA. In results, four patients were identified as having non-motor MSA, who showed isolated autonomic disorders throughout their lives and had minimal pathological changes in the motor systems...
September 22, 2017: Journal of Neurology
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