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liver 3D reconstruction

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https://www.readbyqxmd.com/read/29224266/-application-of-liver-three-dimensional-visualization-technologies-in-the-treatment-planning-of-hepatic-malignant-tumor
#1
P P Li, Z H Wang, G Huang, Z P Huang, Y Li, J S Ni, H Liu, C H Fang, W P Zhou
Objective: To discuss the application of three dimentional(3D)visualization technologies in treatment plan of hepatic malignant tumor. Methods: The clinical data of 300 patients with liver malignant tumor who received treatment from January 2016 to January 2017 in the Third Department of Hepatic Surgery of Eastern Hepatobiliary Surgery Hospital was retrospectively analyzed in this study, including 221 male and 79 female patients aged from 7 to 76 years with median age of 54 years. The median height was 168 cm (115-183 cm), the median weight was 65 kg (20-105 kg) and the median tumor volume was 142 ml (23-2 493 ml)...
December 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29214994/human-liver-segments-role-of-cryptic-liver-lobes-and-vascular-physiology-in-the-development-of-liver-veins-and-left-right-asymmetry
#2
Jill P J M Hikspoors, Mathijs M J P Peeters, Nutmethee Kruepunga, Hayelom K Mekonen, Greet M C Mommen, S Eleonore Köhler, Wouter H Lamers
Couinaud based his well-known subdivision of the liver into (surgical) segments on the branching order of portal veins and the location of hepatic veins. However, both segment boundaries and number remain controversial due to an incomplete understanding of the role of liver lobes and vascular physiology on hepatic venous development. Human embryonic livers (5-10 weeks of development) were visualized with Amira 3D-reconstruction and Cinema 4D-remodeling software. Starting at 5 weeks, the portal and umbilical veins sprouted portal-vein branches that, at 6...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29208767/the-feasibility-of-low-concentration-contrast-and-low-tube-voltage-in-computed-tomography-perfusion-imaging-an-animal-study
#3
Yuning Pan, Aiqin Song, Shizhong Bu, Zhaoqian Chen, Qiuli Huang, Aijing Li
Aim: To investigate the feasibility of low-concentration contrast (270 mg/mL) together with low tube voltage (80 kV) and adaptive iterative dose reduction (AIDR)-3D reconstruction in liver computed tomography (CT) perfusion imaging. Method: A total of 15 healthy New Zealand rabbits received two CT scans each. The first scan (control) was acquired at 100 kV and 100 mA with iopromide (370 mg/mL), while the second scan (experimental) was acquired at 80 kV and 100 mA with iodixanol (270 mg/mL) 24 hours after the first scan...
December 5, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/29205328/quantitative-analysis-of-hepatic-macro-and-microvascular-alterations-during-cirrhogenesis-in-the%C3%A2-rat
#4
Geert Peeters, Charlotte Debbaut, Adrian Friebel, Pieter Cornillie, Winnok H De Vos, Kasper Favere, Ingrid Vander Elst, Tim Vandecasteele, Tim Johann, Luc Van Hoorebeke, Diethard Monbaliu, Dirk Drasdo, Stefan Hoehme, Wim Laleman, Patrick Segers
Cirrhosis represents the end-stage of any persistent chronically active liver disease. It is characterized by the complete replacement of normal liver tissue by fibrosis, regenerative nodules, and complete fibrotic vascularized septa. The resulting angioarchitectural distortion contributes to an increasing intrahepatic vascular resistance, impeding liver perfusion and leading to portal hypertension. To date, knowledge on the dynamically evolving pathological changes of the hepatic vasculature during cirrhogenesis remains limited...
December 4, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/29198945/quantitative-measurements-versus-receiver-operating-characteristics-and-visual-grading-regression-in-ct-images-reconstructed-with-iterative-reconstruction-a-phantom-study
#5
Kristin Jensen, Hilde Kjernlie Andersen, Örjan Smedby, Bjørn Helge Østerås, Anette Aarsnes, Anders Tingberg, Erik Fosse, Anne Catrine Martinsen
RATIONALE AND OBJECTIVES: This study aimed to evaluate the correlation of quantitative measurements with visual grading regression (VGR) and receiver operating characteristics (ROC) analysis in computed tomography (CT) images reconstructed with iterative reconstruction. MATERIALS AND METHODS: CT scans on a liver phantom were performed on CT scanners from GE, Philips, and Toshiba at three dose levels. Images were reconstructed with filtered back projection (FBP) and hybrid iterative techniques (ASiR, iDose, and AIDR 3D of different strengths)...
November 29, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29140117/comparison-of-radiation-dose-and-image-quality-of-abdominopelvic-ct-using-iterative-aidr-3d-and-conventional-reconstructions
#6
Caroline Duarte de Mello-Amoedo, Aparecido Nakano Martins, Adriano Tachibana, Daniella Ferraro Pinho, Ronaldo Hueb Baroni
OBJECTIVE: The purpose of this study is to compare radiation dose and image quality of abdominopelvic CT studies reconstructed with iterative and conventional techniques. MATERIALS AND METHODS: This retrospective study enrolled 99 patients who underwent abdominopelvic CT examinations with the portal venous phase images reconstructed with both filtered back projection and Adaptive Iterative Dose Reduction 3D (AIDR 3D) at different time points. Subjective assessment of image quality was performed by two radiologists who scored axial images for overall quality, sharpness, noise, and acceptability in a blinded fashion...
November 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29128598/histological-and-radiological-evaluation-of-subcutaneous-implants-in-mouse-of-a-3d-printable-material-fulcure-720-and-experimental-application-in-mandibular-reconstruction
#7
J Megías Barrera, L García-Consuegra, A Novoa, S Costilla, S Junquera, G Ascani
INTRODUCTION: The aim of this study was to evaluate the bioactivity of FullCure compared to porous polyethylene implants (Medpor) in rats prior to custom-made scaffold support manufacturing for mandible segmental defects (MSD) reconstruction in sheep. METHODS: 12 Fullcure and Medpor laminaes were implanted in the left and right dorsum respectively of 6 wistar rats. Toxicity was assessed by skin, kidney and liver histopathology 3 months post-implantation. Computed Tomography (CT) was carried out in order to assess radiological differences between implants...
November 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29116221/establishment-of-a-fluorescent-in-situ-hybridization-assay-for-imaging-hepatitis-b-virus-nucleic-acids-in-cell-culture-models
#8
Xiaonan Zhang, Lei Yue, Zhanqing Zhang, Zhenghong Yuan
While chronic hepatitis B remains a global public health problem, the detailed spatiotemporal dynamics of the key molecular events leading to the multiplication and egress of hepatitis B virus (HBV) are still largely unclear. Previously, we developed a chromogenic in situ hybridization assay for detection of HBV RNA, DNA and covalently closed circular DNA in clinical liver biopsies. Here, we report the establishment of a fluorescent in situ hybridization method for the visualization of HBV RNA, HBV core particle DNA and intranuclear DNA in a tetracycline-inducible HBV replication system (HepAD38) and a de novo infection system (HepG2-NTCP)...
November 8, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29103469/improved-clinical-workflow-for-simultaneous-whole-body-pet-mri-using-high-resolution-caipirinha-accelerated-mr-based-attenuation-correction
#9
Martin T Freitag, Matthias Fenchel, Philipp Bäumer, Thorsten Heußer, Christopher M Rank, Marc Kachelrieß, Daniel Paech, Klaus Kopka, Sebastian Bickelhaupt, Antonia Dimitrakopoulou-Strauss, Klaus Maier-Hein, Ralf Floca, Mark E Ladd, Heinz-Peter Schlemmer, Florian Maier
PURPOSE: To explore the value and reproducibility of a novel magnetic resonance based attenuation correction (MRAC) using a CAIPIRINHA-accelerated T1-weighted Dixon 3D-VIBE sequence for whole-body PET/MRI compared to the clinical standard. METHODS: The PET raw data of 19 patients from clinical routine were reconstructed with standard MRAC (MRACstd) and the novel MRAC (MRACcaipi), a prototype CAIPIRINHA accelerated Dixon 3D-VIBE sequence, both acquired in 19 s/bed position...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29084421/hepatogenic-differentiation-capacity-of-human-wharton-s-jelly-mesenchymal-stem-cell-in-a-co-culturing-system-with-endothelial-cells-in-matrigel-collagen-scaffold-in-the-presence-of-fetal-liver-extract
#10
Zahra Khodabandeh, Zahra Vojdani, Tahereh Talaei-Khozani, Soghra Bahmanpour
Background: Human Wharton's jelly mesenchymal stem cells (HWJMSCs) isolated from medical waste product can be considered as an accessible source of cells in regenerative medicine. Stem cell-derived hepatocytes have poor function and need appropriate niche to reconstruct the liver structure. Therefore, we attempted to find a novel approach in differentiating HWJMSCs into functional hepatic cells using 3D culture conditions and liver extract that recapitulates vital stage in liver development...
October 31, 2017: International Journal of Stem Cells
https://www.readbyqxmd.com/read/29078606/depicting-surgical-anatomy-of-the-porta-hepatis-in-living-donor-liver-transplantation
#11
Paul Kelly, Albert Fung, Joy Qu, Paul Greig, Gordon Tait, Jodie Jenkinson, Ian McGilvray, Anne Agur
Visualizing the complex anatomy of vascular and biliary structures of the liver on a case-by-case basis has been challenging. A living donor liver transplant (LDLT) right hepatectomy case, with focus on the porta hepatis, was used to demonstrate an innovative method to visualize anatomy with the purpose of refining preoperative planning and teaching of complex surgical procedures. The production of an animation-enhanced video consisted of many stages including the integration of pre-surgical planning; case-specific footage and 3D models of the liver and associated vasculature, reconstructed from contrast-enhanced CTs...
2017: Journal of visualized surgery
https://www.readbyqxmd.com/read/29023687/a-guide-for-effective-anatomical-vascularization-studies-useful-ex%C3%A2-vivo-methods-for-both-ct-and-mri-imaging-before-dissection
#12
Yohann Renard, Gabriela Hossu, Bailiang Chen, Marine Krebs, Marc Labrousse, Manuela Perez
The objective of this study was to develop a simple and useful injection protocol for imaging cadaveric vascularization and dissection. Mixtures of contrast agent and cast product should provide adequate contrast for two types of ex vivo imaging (MRI and CT) and should harden to allow gross dissection of the injected structures. We tested the most popular contrast agents and cast products, and selected the optimal mixture composition based on their availability and ease of use. All mixtures were first tested in vitro to adjust dilution parameters of each contrast agent and to fine-tune MR imaging acquisition sequences...
October 11, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28940483/improved-quantitative-90-y-bremsstrahlung-spect-ct-reconstruction-with-monte-carlo-scatter-modeling
#13
Yuni K Dewaraja, Se Young Chun, Ravi N Srinivasa, Ravi K Kaza, Kyle C Cuneo, Bill S Majdalany, Paula M Novelli, Michael Ljungberg, Jeffrey A Fessler
PURPOSE: In (90) Y microsphere radioembolization (RE), accurate post-therapy imaging-based dosimetry is important for establishing absorbed dose versus outcome relationships for developing future treatment planning strategies. Additionally, accurately assessing microsphere distributions is important because of concerns for unexpected activity deposition outside the liver. Quantitative (90) Y imaging by either SPECT or PET is challenging. In (90) Y SPECT model based methods are necessary for scatter correction because energy window-based methods are not feasible with the continuous bremsstrahlung energy spectrum...
September 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28917579/microcirculation-in-the-murine-liver-a-computational-fluid-dynamic-model-based-on-3d-reconstruction-from-in-vivo-microscopy
#14
Monica Piergiovanni, Elena Bianchi, Giada Capitani, Irene Li Piani, Lucia Ganzer, Luca G Guidotti, Matteo Iannacone, Gabriele Dubini
The liver is organized in hexagonal functional units - termed lobules - characterized by a rather peculiar blood microcirculation, due to the presence of a tangled network of capillaries - termed sinusoids. A better understanding of the hemodynamics that governs liver microcirculation is relevant to clinical and biological studies aimed at improving our management of liver diseases and transplantation. Herein, we built a CFD model of a 3D sinusoidal network, based on in vivo images of a physiological mouse liver obtained with a 2-photon microscope...
September 2, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28856720/a-double-echo-ultra-short-echo-time-ute-acquisition-for-respiratory-motion-suppressed-high-resolution-imaging-of-the-lung
#15
Jean Delacoste, Jerome Chaptinel, Catherine Beigelman-Aubry, Davide Piccini, Alain Sauty, Matthias Stuber
PURPOSE: Magnetic resonance imaging is a promising alternative to computed tomography for lung imaging. However, organ motion and poor signal-to-noise ratio, arising from short T2*, impair image quality. To alleviate these issues, a new retrospective gating method was implemented and tested with an ultra-short echo time sequence. METHODS: A 3D double-echo ultra-short echo time sequence was used to acquire data during free breathing in ten healthy adult subjects...
August 30, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28841539/salvage-transhepatic-arterial-embolization-after-failed-stage-i-alpps-in-a-patient-with-a-huge-hcc-with-chronic-liver-disease-a-case-report
#16
Zheng Wang, Yuanfei Peng, Qiman Sun, Xudong Qu, Min Tang, Yajie Dai, Zhaoyou Tang, Wan Yee Lau, Jia Fan, Jian Zhou
INTRODUCTION: The degree of hypertrophy of the future liver remnant (FLR) induced by associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in patients with HCC and chronic liver disease is often limited as compared with patients with a healthy liver. PRESENTATION OF CASE: We reported a 53-year-old male who had a huge HCC (14.8×12×9.4cm) arising from a background of hepatitis B liver fibrosis (METAVIR score F3). The ratio of the FLR/standard liver volume (SLV) was 23...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28822820/utility-of-3d-reconstruction-of-2d-liver-computed-tomography-magnetic-resonance-images-as-a-surgical-planning-tool-for-residents-in-liver-resection-surgery
#17
Caitlin T Yeo, Andrew MacDonald, Tamas Ungi, Andras Lasso, Diederick Jalink, Boris Zevin, Gabor Fichtinger, Sulaiman Nanji
OBJECTIVE: A fundamental aspect of surgical planning in liver resections is the identification of key vessel tributaries to preserve healthy liver tissue while fully resecting the tumor(s). Current surgical planning relies primarily on the surgeon's ability to mentally reconstruct 2D computed tomography/magnetic resonance (CT/MR) images into 3D and plan resection margins. This creates significant cognitive load, especially for trainees, as it relies on image interpretation, anatomical and surgical knowledge, experience, and spatial sense...
August 16, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28815906/deep-gray-matter-iron-measurement-in-patients-with-liver-cirrhosis-using-quantitative-susceptibility-mapping-relationship-with-pallidal-t1-hyperintensity
#18
Song Lee, Yoonho Nam, Jinhee Jang, Gun Hyung Na, Dong Goo Kim, Na-Young Shin, Hyun Seok Choi, So-Lyung Jung, Kook-Jin Ahn, Bum-Soo Kim
BACKGROUND: The liver is a central organ for the metabolism of iron and manganese and the places where those metals are commonly deposited overlap in the brain. PURPOSE/HYPOTHESIS: To elucidate the relationship between pallidal T1 hyperintensity and iron deposition in the deep gray matter of liver cirrhosis patients using quantitative susceptibility mapping (QSM). STUDY TYPE: Retrospective case-control study SUBJECTS: In all, 38 consecutive liver cirrhosis patients who received brain magnetic resonance imaging (MRI) as pretransplant evaluation...
August 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28808803/a-prototype-educational-model-for-hepatobiliary-interventions-unveiling-the-role-of-graphic-designers-in-medical-3d-printing
#19
Ramin Javan, Merissa N Zeman
In the context of medical three-dimensional (3D) printing, in addition to 3D reconstruction from cross-sectional imaging, graphic design plays a role in developing and/or enhancing 3D-printed models. A custom prototype modular 3D model of the liver was graphically designed depicting segmental anatomy of the parenchyma containing color-coded hepatic vasculature and biliary tree. Subsequently, 3D printing was performed using transparent resin for the surface of the liver and polyamide material to develop hollow internal structures that allow for passage of catheters and wires...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28755161/usefulness-of-three-dimensional-image-navigation-system-for-evaluation-of-hepatic-artery-before-living-donor-liver-transplantation-a-case-report
#20
Michinori Matsumoto, Shigeki Wakiyama, Hiroaki Shiba, Yuichi Ishida, Yoshiaki Kita, Katsuhiko Yanaga
BACKGROUND: The evaluation of the hepatic vascular anatomy in living liver donors is increasingly being performed by three-dimensional (3D) computed tomography (CT) angiography. However, details of hepatic artery anatomy obtained by 3D CT angiography are not always superior to those obtained by angiography. Here, we report a case in which the 3D image navigation system helped to detect segment II, III, and IV arteries (A2, A3, and A4, respectively) that individually originated from the proper hepatic artery (PHA); this could not be detected by 3D CT angiography...
December 2017: Surgical Case Reports
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