Karl Reis, Allison Wolf, Rubeshan Perumal, Boitumelo Seepamore, Kevin Guzman, Jesse Ross, Ken Cheung, K Rivet Amico, James C M Brust, Nesri Padayatchi, Gerald Friedland, Kogieleum Naidoo, Amrita Daftary, Jennifer Zelnick, Max O'Donnell
INTRODUCTION: For people living with HIV/AIDS, care is commonly delivered through Differentiated Service Delivery (DSD). Although people with multidrug-resistant tuberculosis (MDR-TB) and HIV/AIDS experience severe treatment associated challenges, there is no DSD model to support their treatment. In this study, we defined patterns of medication adherence and characterized longitudinal barriers to inform development of an MDR-TB/HIV DSD framework. METHODS: Adults with MDR-TB and HIV initiating bedaquiline (BDQ) and receiving antiretroviral therapy (ART) in KwaZulu-Natal, South Africa, were enrolled and followed through the end of MDR-TB treatment...
February 6, 2024: Journal of Acquired Immune Deficiency Syndromes: JAIDS