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Platelet rich plasma hyaluronic

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https://www.readbyqxmd.com/read/27924172/hyaluronic-acid-fat-graft-myringoplasty-versus-autologous-platelet-rich-plasma
#1
Salman F Alhabib, Issam Saliba
BACKGROUND: Hyaluronic acid fat graft myringoplasty (HAFGM) is an office-based technique for tympanic membrane perforation (TMP) treatment. It is simple, inexpensive, and performed under local anesthesia at the outpatient office department. We aimed to compare HAFGM technique to a recently described topical use of autologous platelet rich plasma myringoplasty (PRPM) in the repair of TMP. We also aimed to assess the hearing level improvement postoperatively. METHODS: We conducted a prospective study in an adult tertiary care center between January 2015 and January 2016...
January 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27680608/comparison-of-the-effects-of-prp-and-hyaluronic-acid-in-promoting-peripheral-nerve-regeneration-an-experimental-study-with-vascular-conduit-model-in-rats
#2
Cemal Firat, Ahmet Hamdi Aytekin, Mehmet Akif Durak, Yilmaz Geyik, Serkan Erbatur, Metin Dogan, Omer Elmas, Adile Ferda Dagli, Hamit Celik
AIM: Peripheral nerve defects generally occur due to mechanical, chemical, thermal and pathologic causes and the reconstruction is still a challenging problem. In the present study, we aimed to compare the effects of platelet rich plasma (PRP) that has high levels of growth factors and hyaluronic acid (HA) that is known to have positive effects on nerve regeneration by decreasing scar formation in a rat model where they were injected through allogeneic aorta graft in peripheral nerve defects using histopathologic and functional methods...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27660427/clinical-effectiveness-in-severe-knee-osteoarthritis-after-intra-articular-platelet-rich-plasma-therapy-in-association-with-hyaluronic-acid-injection-three-case-reports
#3
Szu-Hsuan Chen, Ta-Shen Kuan, Mu-Jung Kao, Wei-Ting Wu, Li-Wei Chou
Osteoarthritis (OA) is a degenerative disorder resulting from loss of joint cartilage and underlying bone and causes pain and loss of function. The treatment of knee OA is still a challenge because of the poor self-regeneration capacity of cartilage. The nonsurgical interventions include control of the aggravating factor (such as weight control and the use of walking aids), symptomatic treatment (such as acetaminophen or nonsteroidal anti-inflammatory drugs), prolotherapy, and viscosupplementation. However, the combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) has not been widely used because of lack of clinical evidence and several limitations in patients with severe knee OA...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27601078/intra-articular-therapies-for-osteoarthritis
#4
Shirley P Yu, David J Hunter
INTRODUCTION: Conventional medical therapies for osteoarthritis are mainly palliative in nature, aiming to control pain and symptoms. Traditional intra-articular therapies are not recommended in guidelines as first line therapy, but are potential alternatives, when conventional therapies have failed. AREAS COVERED: Current and future intra-articular drug therapies for osteoarthritis are highlighted, including corticosteroids, hyaluronate, and more controversial treatments marketed commercially, namely platelet rich plasma and mesenchymal cell therapy...
October 2016: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/27595866/platelet-rich-plasma-and-hyaluronic-acid-an-efficient-biostimulation-method-for-face-rejuvenation
#5
Betul Gozel Ulusal
BACKGROUND: Cosmetic applications of platelet-rich plasma (PRP) are new, and reports are scarce and dispersed in the literature. There are a variety of commercially available kits and injection techniques, and the number and intervals of injections vary. New investigations should focus on developing a standardized procedure for PRP preparation and application methods to augment its efficacy and potency. OBJECTIVES: In this report, we aim to provide data and commentary to assist and add to current guidelines...
September 5, 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27588219/regeneration-of-cartilage-in-human-knee-osteoarthritis-with-autologous-adipose-tissue-derived-stem-cells-and-autologous-extracellular-matrix
#6
Jaewoo Pak, Jung Hun Lee, Kwang Seung Park, Byeong Chul Jeong, Sang Hee Lee
This clinical case series demonstrates that percutaneous injections of autologous adipose tissue-derived stem cells (ADSCs) and homogenized extracellular matrix (ECM) in the form of adipose stromal vascular fraction (SVF), along with hyaluronic acid (HA) and platelet-rich plasma (PRP) activated by calcium chloride, could regenerate cartilage-like tissue in human knee osteoarthritis (OA) patients. Autologous lipoaspirates were obtained from adipose tissue of the abdominal origin. Afterward, the lipoaspirates were minced to homogenize the ECM...
2016: BioResearch Open Access
https://www.readbyqxmd.com/read/27579267/use-of-platelet-rich-plasma-and-hyaluronic-acid-in-the-treatment-of-complications-of-achilles-tendon-reconstruction
#7
Pietro Gentile, Barbara De Angelis, Annarita Agovino, Fabrizio Orlandi, Alessandra Migner, Camilla Di Pasquali, Valerio Cervelli
BACKGROUND: The platelet-rich plasma (PRP) and hyaluronic acid (HA) constitute a system of tissue growth that can regenerate damaged tissue. This study was performed to evaluate the effect of PRP and HA in treatment of complications of Achilles tendon reconstruction. METHODS: We selected ten patients affected by Achilles tendon injuries resulting from post-surgical complications subsequent to tenorrhaphy and have treated them with autologous PRP in combination with HA to evaluate the improvement of lesions with wound closure...
May 2016: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27554488/-arthrocentesis-of-the-temporomandibular-joint-and-intra-articular-injections%C3%A2-an-update
#8
P Marty, A Louvrier, E Weber, P-A Dubreuil, B Chatelain, C Meyer
INTRODUCTION: Arthocentesis of the temporomandibular joint combined with intra-articular washout and, more recently, intra-articular injection of pharmacological agents has been developed from the 1990s and is nowadays extensively in use for the treatment of temporomandibular dysfunctions (TMDs). The goal of our work was to answer 3 questions: 1. Is intra-articular washout effective for the treatment of TMDs ? 2. What kind of pharmacological agents may nowadays be injected in addition to washout and are these injections useful ? 3...
September 2016: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale
https://www.readbyqxmd.com/read/27512643/novel-technique-of-vulvo-vaginal-rejuvenation-by-lipofilling-and-injection-of-combined-platelet-rich-plasma-and-hyaluronic-acid-a-case-report
#9
Paola Aguilar, Barbara Hersant, Mounia SidAhmed-Mezi, Romain Bosc, Luciano Vidal, Jean Paul Meningaud
BACKGROUND: To describe a new surgical procedure and its results: the vulvo-vaginal rejuvenation by lipofilling and an injection of combined platelet-rich-plasma (PRP) and hyaluronic acid (HA). Sexual life for women is affected by the effect of aging and by post partum traumatism. There are no standard non-invasive treatments to offer to improve the trophic and dimensional alterations of the vulvo-vaginal area. The surgical procedure consists in a vaginoplasty by lipofilling of the posterior vaginal wall far from the vascular axes and with an injection of an injection of combined PRP and HA subcutaneously in the perineum...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27400716/functional-recovery-in-osteoarthritic-chondrocytes-through-hyaluronic-acid-and-platelet-rich-plasma-inhibited-infrapatellar-fat-pad-adipocytes
#10
Wei-Hong Chen, Chien-Min Lin, Chiung-Fang Huang, Wei-Che Hsu, Chian-Her Lee, Keng-Liang Ou, Navneet Kumar Dubey, Win-Ping Deng
BACKGROUND: Recent studies have shown evidence that higher adiposity in the infrapatellar fat pad (IFP) induces inflammatory phenotypes in the knee joint and thereby contributes to the development and progression of osteoarthritis (OA). In particular, IFP adipocyte-derived inflammatory cytokines participate in pathological events. Our previous research has already addressed the therapeutic efficacy of hyaluronic acid and platelet-rich plasma (HA+PRP), including the promotion of cartilage regeneration and the inhibition of inflammation...
October 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27384560/intra-articular-injections-of-platelet-rich-plasma-versus-hyaluronic-acid-in-the-treatment-of-osteoarthritic-knee-pain-a-randomized-clinical-trial-in-the-context-of-the-spanish-national-health-care-system
#11
Elvira Montañez-Heredia, Sofia Irízar, Pedro J Huertas, Esperanza Otero, Marta Del Valle, Isidro Prat, Macarena S Díaz-Gallardo, Macarena Perán, Juan A Marchal, María Del Carmen Hernandez-Lamas
Intra-articular injection of platelet-rich plasma (PRP) has been established as a suitable treatment for knee osteoarthritis. Here, we present a double-blind randomized controlled clinical trial, conducted in a public Hospital of the Spanish National Health Care System, to evaluate the efficacy of injecting autologous PRP versus hyaluronic acid (HA) in knee osteoarthritis. PRP was manufactured in Malaga's Regional Blood Center (Spain). Patients that met the eligibility criteria were randomized into a PRP group or a HA group...
July 2, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27364372/is-arthrocentesis-plus-platelet-rich-plasma-superior-to-arthrocentesis-plus-hyaluronic-acid-for-the-treatment-of-temporomandibular-joint-osteoarthritis-a-randomized-clinical-trial
#12
S Cömert Kiliç, M Güngörmüş
A randomized clinical trial was implemented in adult patients with temporomandibular joint osteoarthritis (TMJ OA). The sample comprised 49 osteoarthritic joints in 31 consecutive patients. Patients were divided randomly into two groups according to the treatment technique applied: the platelet-rich plasma (PRP) group patients underwent initial arthrocentesis plus PRP injection and then four consecutive PRP injections; the hyaluronic acid (HA) group patients underwent one session of arthrocentesis plus HA injection...
June 27, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27359284/biological-therapies-for-cartilage-lesions-in-the-hip-a-new-horizon
#13
Jorge Chahla, Robert F LaPrade, Rodrigo Mardones, Johnny Huard, Marc J Philippon, Shane Nho, Omer Mei-Dan, Cecilia Pascual-Garrido
Treatment of hip cartilage disease is challenging, and there is no clear algorithm to address this entity. Biomarkers are arising as promising diagnostic tools because they could play a role in the early assessment of the prearthritic joint and as a prognostic factor before and after treatment. The potential effect of biomarkers may be used to categorize individuals at risk of evolving to severe osteoarthritis, to develop new measures for clinical progression of the disease, and to develop new treatment options for the prevention of osteoarthritis progression...
July 1, 2016: Orthopedics
https://www.readbyqxmd.com/read/27310019/platelet-rich-plasma-and-hyaluronic-acid-blend-for-the-treatment-of-osteoarthritis-rheological-and-biological-evaluation
#14
Fabrizio Russo, Matteo D'Este, Gianluca Vadalà, Caterina Cattani, Rocco Papalia, Mauro Alini, Vincenzo Denaro
INTRODUCTION: Osteoarthritis (OA) is the most common musculoskeletal disease. Current treatments for OA are mainly symptomatic and inadequate since none results in restoration of fully functional cartilage. Hyaluronic Acid (HA) intra-articular injections are widely accepted for the treatment of pain associated to OA. The goal of HA viscosupplementation is to reduce pain and improve viscoelasticity of synovial fluid. Platelet-rich plasma (PRP) has been also employed to treat OA to possibly induce cartilage regeneration...
2016: PloS One
https://www.readbyqxmd.com/read/27308248/use-of-platelet-rich-plasma-prp-and-hyaluronic-acid-in-treatment-of-extremity-gunshot-injuries-a-case-report
#15
Valerio Cervelli, Pietro Gentile, Lorenzo Brinci, Camilla Di Pasquali, Ilaria Bocchini, Barbara De Angelis
No abstract text is available yet for this article.
January 2016: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27302491/anaesthetics-steroids-and-platelet-rich-plasma-prp-in-ultrasound-guided-musculoskeletal-procedures
#16
Antonio Barile, Alice La Marra, Francesco Arrigoni, Silvia Mariani, Luigi Zugaro, Alessandra Splendiani, Ernesto Di Cesare, Alfonso Reginelli, Marcello Zappia, Luca Brunese, Ejona Duka, Giampaolo Carrafiello, Carlo Masciocchi
This review aims to evaluate the role of anaesthetics, steroids and platelet-rich plasma (PRP) employed with ultrasound-guided injection in the management of musculoskeletal pathology of the extremities. Ultrasound-guided injection represents an interesting and minimally invasive solution for the treatment of tendon and joint inflammatory or degenerative diseases. The availability of a variety of new drugs such as hyaluronic acid and PRP provides expansion of the indications and therapeutic possibilities. The clinical results obtained in terms of pain reduction and functional recovery suggest that the use of infiltrative procedures can be a good therapeutic alternative in degenerative and inflammatory joint diseases...
September 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27300455/soft-tissue-augmentation-of-the-face-with-autologous-platelet-derived-growth-factors-and-tricalcium-phosphate-microtomography-evaluation-of-mice
#17
Antonio Scarano, Luca Valbonetti, Massimiliano Marchetti, Felice Lorusso, Maurizio Ceccarelli
BACKGROUND: The platelets used in oral, maxillofacial, and plastic surgery are generally grouped as concentrated platelet-rich plasma. The general principle of production consists of a centrifugation, making it possible to eliminate red blood cells, then acellular plasma, to preserve only the concentrated platelets. OBJECTIVE: The aim of the present study was that micro porous tricalcium phosphate (β-TCP) mixed with autologous platelet-derived growth factors could be an alternative to fat and hyaluronic acid which are widely used for oral and maxillofacial soft tissue augmentation...
July 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27267529/platelet-rich-plasma-for-osteoarthritis-treatment
#18
Eduardo Knop, Luiz Eduardo de Paula, Ricardo Fuller
We conducted a comprehensive and systematic search of the literature on the use of platelet-rich plasma (PRP) in the treatment of osteoarthritis, using the Medline, Lilacs, Cochrane and SciELO databases, from May 2012 to October 2013. A total of 23 studies were selected, with nine being controlled trials and, of these, seven randomized, which included 725 patients. In this series, the group receiving PRP showed improvement in pain and joint function compared to placebo and hyaluronic acid. The response lasted up to two years and was better in milder cases...
March 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27147429/-muscle-tendon-and-joint-injections-what-is-the-evidence
#19
R Lenz, M Kieb, P Diehl, C Grim, S Vogt, T Tischer
Injections at tendon insertions, in muscles and in joints are an important instrument in the conservative treatment of musculoskeletal diseases, for acute injuries as well as for chronic degenerative diseases. Local anesthetic agents and glucocorticoids are well-established medications; however, severe side effects, such as chondrolysis have sometimes been reported, particularly for local anesthetic agents. In addition platelet rich plasma (PRP) and hyaluronic acid are also widely used; however, the clinical effectiveness has not always been proven...
May 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27128240/acne-scar-treatment-a-multimodality-approach-tailored-to-scar-type
#20
Lisa A Zaleski-Larsen, Sabrina G Fabi, Timothy McGraw, Mark Taylor
BACKGROUND: Acne scarring can be classified into atrophic icepick, boxcar, and rolling scars in addition to keloidal and hypertrophic scars. Additionally, these scars can be erythematous, hyperpigmented, and/or hypopigmented. Each scar type has a different structural cause warranting a customized approach. Many cosmetic options exist to address these changes individually, but little literature exists about the safety and efficacy of combining such procedures and devices. METHODS: A Medline search was performed on combination treatments because it relates to facial acne scarring, and results are summarized...
May 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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