Dawei Zhou, Tong Li, Yi Lv, Dijia Wang, Rongli Zhang, Qing Lin, Chao Wang, Dong Zhao, Shuyang Fei, Wei He
BACKGROUND: To estimate the incidence, risk factors, and impact on mortality and functional outcomes for early coagulopathy after the return of spontaneous circulation (ROSC) in pediatric out-of-hospital cardiac arrest (OHCA) patients. METHODS: A post hoc analysis of the Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital (THAPCA-OH) trial was conducted. Early coagulopathy was defined as presence of at least one of the following coagulation abnormalities upon admission: international standard ratio (INR), platelets, and age-adjusted activated partial thromboplastin time (APTT) within 6 h after OHCA and before therapeutic hypothermia initiation...
October 11, 2022: Thrombosis Journal