keyword
MENU ▼
Read by QxMD icon Read
search

Pediatric cardiac arrest hypothermia

keyword
https://www.readbyqxmd.com/read/27849689/9-therapeutic-hypothermia-after-pediatric-cardiac-arrest-in-hospital-trial
#1
Frank Moler, J Michael Dean
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27679965/pediatric-out-of-hospital-cardiac-arrest-characteristics-and-their-association-with-survival-and-neurobehavioral-outcome
#2
Kathleen L Meert, Russell Telford, Richard Holubkov, Beth S Slomine, James R Christensen, J Michael Dean, Frank W Moler
OBJECTIVE: To investigate relationships between cardiac arrest characteristics and survival and neurobehavioral outcome among children recruited to the Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital trial. DESIGN: Secondary analysis of Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital trial data. SETTING: Thirty-six PICUs in the United States and Canada. PATIENTS: All children (n = 295) had chest compressions for greater than or equal to 2 minutes, were comatose, and required mechanical ventilation after return of circulation...
September 27, 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27509385/functional-outcome-trajectories-after-out-of-hospital-pediatric-cardiac-arrest
#3
Faye S Silverstein, Beth S Slomine, James Christensen, Richard Holubkov, Kent Page, J Michael Dean, Frank W Moler
OBJECTIVES: To analyze functional performance measures collected prospectively during the conduct of a clinical trial that enrolled children (up to age 18 yr old), resuscitated after out-of-hospital cardiac arrest, who were at high risk of poor outcomes. DESIGN: Children with Glasgow Motor Scale score less than 5, within 6 hours of resuscitation, were enrolled in a clinical trial that compared two targeted temperature management interventions (THAPCA-OH, NCT00878644)...
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27403966/asian-targeted-temperature-management-task-panel-report
#4
Mayuki Aibiki, Ming-Chou Chiang, Sombat Muengtaweepongsa, Sohil Pothiawala, Chien-Hua Huang
In the fields of emergency and critical care, targeted temperature management has become a critical issue and particularly popular in clinical practices throughout Asia. As more research is carried out, evidence and concepts about targeted temperature management continue to evolve. Areas of interest include new 2015 resuscitation guidelines, temperature management in pediatrics, and integrated care and neurological monitoring for cardiac arrest patients. The Asian Targeted Temperature Management task panel includes colleagues from various Asian countries and allows them to exchange experiences in a professional environment...
July 12, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27362855/targeted-temperature-management-after-pediatric-cardiac-arrest-due-to-drowning-outcomes-and-complications
#5
Frank W Moler, Jamie S Hutchison, Vinay M Nadkarni, Faye S Silverstein, Kathleen L Meert, Richard Holubkov, Kent Page, Beth S Slomine, James R Christensen, J Michael Dean
OBJECTIVE: To describe outcomes and complications in the drowning subgroup from the Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital trial. DESIGN: Exploratory post hoc cohort analysis. SETTING: Twenty-four PICUs. PATIENTS: Pediatric drowning cases. INTERVENTIONS: Therapeutic hypothermia versus therapeutic normothermia. MEASUREMENTS AND MAIN RESULTS: An exploratory study of pediatric drowning from the Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital trial was conducted...
August 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27200324/rationale-for-implementation-of-warm-cardiac-surgery-in-pediatrics
#6
Yves Durandy
Cardiac surgery was developed thanks to the introduction of hypothermia and cardiopulmonary bypass in the early 1950s. The deep hypothermia protective effect has been essential to circulatory arrest complex cases repair. During the early times of open-heart surgery, a major concern was to decrease mortality and to improve short-term outcomes. Both mortality and morbidity dramatically decreased over a few decades. As a consequence, the drawbacks of deep hypothermia, with or without circulatory arrest, became more and more apparent...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27124565/family-burden-after-out-of-hospital-cardiac-arrest-in-children
#7
Kathleen L Meert, Beth S Slomine, James R Christensen, Russell Telford, Richard Holubkov, J Michael Dean, Frank W Moler
OBJECTIVES: To describe family burden among caregivers of children who survived out-of-hospital cardiac arrest and who were at high risk for neurologic disability and examine relationships between family burden, child functioning, and other factors during the first year post arrest. DESIGN: Secondary analysis of data from the Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital trial. SETTING: Thirty-six PICUs in the United States and Canada...
June 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27033251/therapeutic-hypothermia-protects-against-ischemia-induced-impairment-of-synaptic-plasticity-following-juvenile-cardiac-arrest-in-sex-dependent-manner
#8
R M Dietz, G Deng, J E Orfila, X Hui, R J Traystman, P S Herson
Pediatric cardiac arrest (CA) often leads to poor neurologic outcomes, including deficits in learning and memory. The only approved treatment for CA is therapeutic hypothermia, although its utility in the pediatric population remains unclear. This study analyzed the effect of mild therapeutic hypothermia after CA in juvenile mice on hippocampal neuronal injury and the cellular model of learning and memory, termed long-term potentiation (LTP). Juvenile mice were subjected to cardiac arrest and cardiopulmonary resuscitation (CA/CPR) followed by normothermia (37°C) and hypothermia (30°C, 32°C)...
June 14, 2016: Neuroscience
https://www.readbyqxmd.com/read/26940987/neurobehavioral-outcomes-in-children-after-out-of-hospital-cardiac-arrest
#9
Beth S Slomine, Faye S Silverstein, James R Christensen, Richard Holubkov, Kent Page, J Michael Dean, Frank W Moler
OBJECTIVE: This study examined 12-month neurobehavioral outcomes in children who survived out-of-hospital cardiac arrest (OH-CA), were comatose after resuscitation, and were enrolled in a clinical trial to evaluate targeted temperature management to hypothermia (33.0°C) or normothermia (36.8°C) (Therapeutic Hypothermia after Pediatric Cardiac Arrest, Out-of-Hopsital [THAPCA-OH]; NCT00878644). METHODS: Baseline functioning was assessed by caregiver responses on the Vineland Adaptive Behavior Scales-Second Edition (VABS-II) soon after OH-CA (based on functioning before OH-CA); children with broadly normal baseline functioning (VABS-II ≥70) were included in the THAPCA-OH primary outcome...
April 2016: Pediatrics
https://www.readbyqxmd.com/read/26863153/pediatric-neurocritical-care-in-the-21st-century-from-empiricism-to-evidence
#10
Mark S Wainwright, Gregory Hansen, Juan Piantino
PURPOSE OF REVIEW: Approximately one in five children admitted to a pediatric ICU have a new central nervous system injury or a neurological complication of their critical illness. The spectrum of neurologic insults in children is diverse and clinical practice is largely empirical, as few randomized, controlled trials have been reported. This lack of data poses a substantial challenge to the practice of pediatric neurocritical care (PNCC). PNCC has emerged as a novel subspecialty, and its presence is expanding within tertiary care centers...
April 2016: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/26569847/186-exploratory-study-of-duration-of-hypothermia-for-neuroprotection-after-pediatric-cardiac-arrest
#11
Ericka Fink, Anthony Fabio, Ashok Panigrahy, Rachel Berger, Robert Clark, Derek Angus, Michael Bell, Patrick Kochanek
No abstract text is available yet for this article.
December 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/26562493/feasibility-study-evaluating-therapeutic-hypothermia-for-refractory-status-epilepticus-in-children
#12
MULTICENTER STUDY
Sandra D W Buttram, Alicia K Au, Joshua Koch, Karen Lidsky, Kristin McBain, Nicole O'Brien, Brandon A Zielinski, Michael J Bell
Pediatric refractory status epilepticus (RSE) is a neurological emergency with significant morbidity and mortality, which lacks consensus regarding diagnosis and treatment(s). Therapeutic hypothermia (TH) is an effective treatment for RSE in preclinical models and small series. In addition, TH is a standard care for adults after cardiac arrest and neonates with hypoxic-ischemic encephalopathy. The purpose of this study was to identify the feasibility of a study of pediatric RSE within a research group (Pediatric Neurocritical Care Research Group [PNCRG])...
December 2015: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/26549388/difficulty-interpreting-the-results-of-some-trials-the-case-of-therapeutic-hypothermia-after-pediatric-cardiac-arrest
#13
EDITORIAL
Jean-Louis Vincent, Fabio S Taccone
No abstract text is available yet for this article.
2015: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26323408/the-impact-of-hypothermia-on-the-pharmacokinetics-of-drugs-used-in-neonates-and-young-infants
#14
REVIEW
P Pokorna, E D Wildschut, V Vobruba, John N van den Anker, D Tibboel
Therapeutic hypothermia (HT) is frequently used in neonates with hypoxic-ischemic encephalopathy and young infants during cardiopulmonary bypass (CPB). Hypothermia and CPB result in physiological changes contributing to pharmacokinetic (PK) and pharmacodynamic (PD) changes. Changes in the absorption, the volume of distribution (Vd) and the total body clearance (CL) of drugs used during hypothermia and CPB might lead to the interindividual PK variability resulting in either insufficient or toxic plasma concentrations and have an impact on the biodisposition and action of drugs...
2015: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/26111746/surgical-management-of-vascular-stents-in-pediatric-cardiac-surgery-clues-for-a-staged-partnership
#15
Juan-Miguel Gil-Jaurena, José-Luis Zunzunegui, Ramón Pérez-Caballero, Ana Pita, María-Teresa González-López, Fernando Ballesteros, Alejandro Rodríguez, Constancio Medrano
Complex cases undergo step surgical and percutaneous procedures, including stent deployment. Concerns arise on stent removal at latest surgery. Our initial experience is presented. Forty-six stents in 35 patients were partially or totally removed at surgery. Univentricular heart was diagnosed in 20 patients. Stents were previously deployed in: ductus (6), right ventricle outflow tract (12), atrial septal defect (4), right pulmonary artery (4), left pulmonary artery (16), inferior vena cava (2), superior vena cava (1) and ascending aorta (1)...
December 2015: Pediatric Cardiology
https://www.readbyqxmd.com/read/26052804/extracorporeal-membrane-oxygenation-for-cardiac-arrest-during-moyamoya-cerebral-revascularization-surgery-case-report
#16
Omar Choudhri, Aatman Shah, Jennifer Basarab-Tung, Richard A Jaffe, Gary K Steinberg
The authors describe the case of a 51-year-old man with bilateral moyamoya disease and prior strokes who developed an asystolic cardiac arrest while undergoing revascularization surgery under mild hypothermia. The patient was successfully treated with venoarterial (VA) extracorporeal membrane oxygenation (ECMO) after manual cardiopulmonary resuscitation (CPR) was unsuccessful for 45 minutes. ECMO is a cardiopulmonary support system that is indicated for respiratory failure in pediatric and adult patients. It is increasingly being used as an extension to mechanical CPR for patients who have suffered cardiac arrest if the underlying cause of cardiac arrest is thought to be reversible...
September 2015: Journal of Neurosurgery
https://www.readbyqxmd.com/read/26042193/targeted-temperature-management-in-pediatric-central-nervous-system-disease
#17
Robert Newmyer, Jenny Mendelson, Diana Pang, Ericka L Fink
Acute central nervous system conditions due to hypoxic-ischemic encephalopathy, traumatic brain injury (TBI), status epilepticus, and central nervous system infection/inflammation, are a leading cause of death and disability in childhood. There is a critical need for effective neuroprotective therapies to improve outcome targeting distinct disease pathology. Fever, defined as patient temperature > 38°C, has been clearly shown to exacerbate brain injury. Therapeutic hypothermia (HT) is an intervention using targeted temperature management that has multiple mechanisms of action and robust evidence of efficacy in multiple experimental models of brain injury...
March 1, 2015: Current Treatment Options in Pediatrics
https://www.readbyqxmd.com/read/26007621/normothermic-versus-hypothermic-cardiopulmonary-bypass-in-children-undergoing-open-heart-surgery-thermic-2-study-protocol-for-a-randomized-controlled-trial
#18
Sarah Baos, Karen Sheehan, Lucy Culliford, Katie Pike, Lucy Ellis, Andrew J Parry, Serban Stoica, Mohamed T Ghorbel, Massimo Caputo, Chris A Rogers
BACKGROUND: During open heart surgery, patients are connected to a heart-lung bypass machine that pumps blood around the body ("perfusion") while the heart is stopped. Typically the blood is cooled during this procedure ("hypothermia") and warmed to normal body temperature once the operation has been completed. The main rationale for "whole body cooling" is to protect organs such as the brain, kidneys, lungs, and heart from injury during bypass by reducing the body's metabolic rate and decreasing oxygen consumption...
May 25, 2015: JMIR Research Protocols
https://www.readbyqxmd.com/read/25980372/pediatric-extracorporeal-membrane-oxygenation-an-introduction-for-emergency-medicine-physicians
#19
REVIEW
Lynn P Gehrmann, John W Hafner, Daniel L Montgomery, Klayton W Buckley, Randall S Fortuna
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) therapy has supported critically ill pediatric patients in the intensive care unit setting with cardiac and respiratory failure. This therapy is beginning to transition to the emergency department setting. OBJECTIVE OF REVIEW: This article describes the fundamentals of ECMO and familiarizes the emergency medicine physician with its use in critically ill pediatric patients. DISCUSSION: ECMO can be utilized as either venoarterial (VA) or venovenous (VV), to support oxygenation and perfusion in respiratory failure, sepsis, cardiac arrest, and environmental hypothermia...
October 2015: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25861505/therapeutic-hypothermia-and-out-of-hospital-cardiac-arrest-in-a-child-with-hypertrophic-obstructive-cardiomyopathy
#20
Nancy Spurkeland, Gregory Bennett, Chandran Alexander, Dennis Chang, Gary Ceneviva
Neurologic outcomes following pediatric cardiac arrest are consistently poor. Early initiation of cardiopulmonary resuscitation has been shown to have positive effects on both survival to hospital discharge, and improved neurological outcomes after cardiac arrest. Additionally, the use of therapeutic hypothermia may improve survival in pediatric cardiac arrest patients admitted to the intensive care unit. We report a child with congenital hypertrophic obstructive cardiomyopathy and an out-of-hospital cardiac arrest, in whom the early initiation of effective prolonged cardiopulmonary resuscitation and subsequent administration of therapeutic hypothermia contributed to a positive outcome with no gross neurologic sequelae...
2015: Case Reports in Pediatrics
keyword
keyword
10677
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"