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calcium urolithiasis

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https://www.readbyqxmd.com/read/28529700/effect-of-citrus-based-products-on-urine-profile-a-systematic-review-and-meta-analysis
#1
Fakhri Rahman, Ponco Birowo, Indah S Widyahening, Nur Rasyid
Background. Urolithiasis is a disease with high recurrence rate, 30-50% within 5 years. The aim of the present study was to learn the effects of citrus-based products on the urine profile in healthy persons and people with urolithiasis compared to control diet and potassium citrate.  Methods. A systematic review was performed, which included interventional, prospective observational and retrospective studies, comparing citrus-based therapy with standard diet therapy, mineral water, or potassium citrate. A literature search was conducted using PUBMED, COCHRANE, and Google Scholar with "citrus or lemonade or orange or grapefruit or lime or juice" and "urolithiasis" as search terms...
2017: F1000Research
https://www.readbyqxmd.com/read/28528955/potential-therapeutic-activity-of-phlogacanthus-thyrsiformis-hardow-mabb-flower-extract-and-its-biofabricated-silver-nanoparticles-against-chemically-induced-urolithiasis-in-male-wistar-rats
#2
Poppy Das, Kiran Kumar, Arunai Nambiraj, Reshma Rajan, Rajendra Awasthi, Kamal Dua, Himaja M
Urolithiasis is a painful disorder in which stones are formed in the kidney, bladder or urethra. There are no proper therapeutic treatments available for kidney stones and people suffering from larger stones have to undergo surgery which has many side effects. A natural remedy with therapeutic effects that can dissipate and remove even the larger stones would eliminate the need of a surgery and the risks associated with it. The flowers of Phlogacanthus thyrsiformis used in culinary recipes in the north eastern India are also widely used as a folklore medicine for the treatment of kidney stones and liver disorders...
May 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28526618/24-hour-urine-metabolic-differences-between-solitary-and-multiple-stone-formers-results-of-the-collaboration-on-urolithiasis-in-pediatrics-cup-working-group
#3
Theodore R Saitz, Solange Mongoue-Tchokote, Cynthia Sharadin, Dana W Giel, Sean Corbett, Larisa Kovacevic, Aaron P Bayne
INTRODUCTION: Specific factors associated with the risk of developing pediatric urinary stone disease remain unclear, especially those that may be associated with recurrent stone disease. OBJECTIVE: We compared the results of 24-h urine collections in children with a solitary stone episode to those with multiple stone episodes to determine if there is a difference that may be associated with multiple stone formation in children. STUDY DESIGN: A multi-institutional retrospective analysis was completed to assess 24-h urinary metabolic profiles in children with urolithiasis aged 2-18 years old...
April 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28480348/antiurolithic-effect-of-olive-oil-in-a-mouse-model-of-ethylene-glycol-induced-urolithiasis
#4
Mohammed Alenzi, Shaik Rahiman, Bilal Ahmad Tantry
PURPOSE: At present, commercially available antiurolithic drugs have more adverse effects than potential therapeutic or preventive effects with chronic use. With this in mind, the present study was designed to assess the antiurolithic effect of olive oil in a mouse model of ethylene glycol (EG)-induced urolithiasis. MATERIALS AND METHODS: Adult albino mice were divided into 6 groups. Group I was fed the vehicle only. Group II was supplemented with 0.75% EG alone in drinking water during the experimental period to initiate deposition of calcium oxalate in kidneys, which leads to urolithiasis in animals...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28467511/urinary-metals-in-a-spontaneous-canine-model-of-calcium-oxalate-urolithiasis
#5
Eva Furrow, Molly E McCue, Jody P Lulich
Calcium oxalate urolithiasis is a common and painful condition in people. The pathogenesis of this disease is complex and poorly understood. Laboratory animal and in vitro studies have demonstrated an effect of multiple trace metals in the crystallization process, and studies in humans have reported relationships between urinary metal concentrations and stone risk. Dogs are a spontaneous model of calcium oxalate urolithiasis, and the metal content of canine calcium oxalate stones mirrors that of human stones...
2017: PloS One
https://www.readbyqxmd.com/read/28458875/a-rare-case-of-mediastinal-functioning-parathyroid-adenoma-removed-successfully-with-thoracoscopy
#6
Masashi Ishikawa, Shin-Ichi Sumitomo, Naoto Imamura, Tomoki Nishida, Katsutaka Mineura
We report here a rare case of primary hyperparathyroidism that was associated with an ectopic parathyroid adenoma located in the mediastinum. A 66-year-old woman suffering from primary hyperparathyroidism had been followed-up on an outpatient basis for over 10 years. She suffered from persistent urolithiasis and osteopenia due to hypercalcemia. After technetium-99-sestamibi (99mTc-MIBI) scintigraphy revealed an ectopic adenoma in the superior mediastinum, thoracoscopic resection of the tumor was performed. Subsequently, her serum parathyroid hormone (PTH) level decreased dramatically and her serum calcium concentration was restored to normal...
April 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28458427/antiurolithiatic-and-antioxidant-efficacy-of-musa-paradisiaca-pseudostem-on-ethylene-glycol-induced-nephrolithiasis-in-rat
#7
Padma Nibash Panigrahi, Sahadeb Dey, Monalisa Sahoo, Ananya Dan
OBJECTIVE: Musa paradisiaca has been used in the treatment of urolithiasis by the rural people in South India. Therefore, we plan to evaluate its efficacy and possible mechanism of antiurolithiatic effect to rationalize its medicinal use. MATERIALS AND METHODS: Urolithiasis was induced in hyperoxaluric rat model by giving 0.75% ethylene glycol (EG) for 28 days along with 1% ammonium chloride (AC) for the first 14 days. Antiurolithiatic effect of aqueous-ethanol extract of M...
January 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28446830/bryophyllum-pinnatum-leaf-extracts-prevent-formation-of-renal-calculi-in-lithiatic-rats
#8
Mahendra Yadav, Vijay D Gulkari, Manish M Wanjari
BACKGROUND: Bryophyllum pinnatum, commonly known as Pattharcaṭṭa, is used traditionally in ethnomedicinal practices for the treatment of kidney stone and urinary insufficiency. AIM: The present study evaluated the effect of Bryophyllum pinnatum on ethylene glycol (EG)-induced renal calculi in rats. MATERIALS AND METHODS: Renal calculi were induced in rats by administration of 0.75% EG in drinking water and co-treated orally with standard drug, Cystone (750 mg/kg), or alcoholic and hydro-alcoholic extracts in doses of 100, 200 and 400 mg/kg for 28 days...
October 2016: Ancient Science of Life
https://www.readbyqxmd.com/read/28439382/association-between-adiponectin-and-insulin-resistance-in-diabetic-urolithiasis
#9
Dona Devasia, Kavitha Meiyappan, Palani Selvam Mohanraj, Dorairajan Lalgudi Narayanan, Gandhipuram Periyasamy Senthilkumar, Md Yasir
OBJECTIVES: The prevalence of urolithiasis is increasing worldwide. Diabetes mellitus (DM) is characterized by insulin resistance, which increases the risk of kidney stone formation. Adiponectin is an insulin-sensitizing and anti-inflammatory cytokine, which is known to improve glucose tolerance and insulin resistance in humans. The association of insulin and adiponectin with kidney stones is not clear. Hence, the present study aim to assess the serum levels of adiponectin and insulin resistance in DM patients with urolithiasis in comparison to those without...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28435765/chronic-nephropathy-from-dietary-hyperoxaluria-sustained-improvement-of-renal-function-after-dietary-intervention
#10
Yijuan Sun, Bruce L Horowitz, Karen S Servilla, Joanna R Fair, Darlene Vigil, Kavitha Ganta, Larry Massie, Antonios H Tzamaloukas
A 56-year-old man with stable chronic kidney disease (CKD) for two years following a single episode of calcium oxalate urolithiasis developed progressive elevation of his serum creatinine concentration. Urinalysis revealed pyuria and white cell casts, a few red blood cells, minimal proteinuria, and no crystals. Urine culture was sterile. Gallium scintigraphy was consistent with interstitial nephritis. Proton pump inhibitor intake was discontinued, and a short course of oral corticosteroids was initiated. Percutaneous kidney biopsy, performed because of the continued deterioration of renal function to a minimum estimated glomerular filtration rate (eGFR) value of 15 mL/min per 1...
March 20, 2017: Curēus
https://www.readbyqxmd.com/read/28427449/urolithiasis-analysis-in-a-multiethnic-population-at-a-tertiary-hospital-in-nairobi-kenya
#11
Francis K Wathigo, Alfred Hayombe, Daniel Maina
BACKGROUND: Urolithiasis is a global problem whose incidence is reported to be on the rise across the world. Previously, urolithiasis was reported as being rare among the indigenous African population but recent data suggest otherwise. This study reviewed the demographic and clinical characteristics of patients with urolithiasis seen at the Aga Khan University hospital Nairobi (AKUHN) as well as the chemical composition of the stones and the modalities of therapy used. METHODS: This was a retrospective study which utilized patients' clinical and laboratory records from 2013 to 2014...
April 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28422036/physicochemical-factors-of-the-urine-of-children-with-hypercalciuria
#12
Mercedes Ubetagoyena-Arrieta, Jorge Martínez Sáenz de Jubera, María Nieves Corera-Casty, Eduardo González Pérez-Yarza, Irati García-Albizua
OBJECTIVE: Hypercalciuria is a common lithogenic risk factor. The aim of this study was, first, to study the characteristics of urine biochemical factors of children with hypercalciuria (HC) and compare them with those of children without hypercalciuria. Second, to analyze the differences between children with HC and lithiasis (HCL) and children with HC and no lithiasis (HCNL). METHODS: The sample was composed by 111 cases with HC, divided into 2 groups: HCNL group, consisting of 93 cases with no personal history of kidney stones, and HCL group, 18 cases with personal history of kidney stones...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28416732/prevalence-of-kidney-stones-and-associated-risk-factors-in-the-shunyi-district-of-beijing
#13
Y G Jiang, L H He, G T Luo, X D Zhang
INTRODUCTION: Kidney stone formation is a multifactorial condition that involves interaction of environmental and genetic factors. Presence of kidney stones is strongly related to other diseases, which may result in a heavy economic and social burden. Clinical data on the prevalence and influencing factors in kidney stone disease in the north of China are scarce. In this study, we explored the prevalence of kidney stone and potentially associated risk factors in the Shunyi District of Beijing, China...
April 18, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28394535/-metaphylaxis-of-urolithiasis-new-look-modern-approach-implementation-in-a-mobile-application
#14
N K Gadzhiev, S S Brovkin, V E Grigorev, V V Dmitriev, V A Malkhasyan, D D Shkarupa, A V Pisarev, D A Mazurenko, V M Obidnyak, I N Orlov, S V Popov, N S Tagirov, S V Petrov
AIM: To analyze the sub-segment of mHealth devoted to assessing of the risk of recurrent stone formation and metaphylaxis of stone formation. To design a smartphone application (app.) in Russian language for urolithiasis patients. MATERIALS AND METHODS: Three working groups of urologists from three St. Petersburg clinics searched for downloadable medical applications relevant to the above requirements. After searching and analyzing existing medical applications, the most acceptable design and structure of our own application were identified...
April 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28365270/calcium-to-citrate-ratio-distinguishes-solitary-and-recurrent-urinary-stone-forming-children
#15
William DeFoor, Elizabeth Jackson, Marion Schulte, Zaheer Alam, John Asplin
PURPOSE: The prevalence of urinary stone disease is increasing in children. We previously reported a high rate of urinary metabolic abnormalities, including hypercalciuria and hypocitraturia, in stone forming children. In this study we determined whether calcium-to-citrate ratio could help predict those at risk for recurrent stone formation. MATERIALS AND METHODS: We conducted a retrospective cohort study to assess calcium-to-citrate ratios in children with urolithiasis...
March 30, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28361944/association-study-of-reported-significant-loci-at-5q35-3-7p14-3-13q14-1-and-16p12-3-with-urolithiasis-in-chinese-han-ethnicity
#16
Lujia Wang, Chenchen Feng, Guanxiong Ding, Xiaoling Lin, Peng Gao, Haowen Jiang, Jianfeng Xu, Qiang Ding, Zhong Wu
In this study, we aimed to validate the association of 8 reported significant loci at 5q35.3, 7p14.3, 13q14.1 and 16p12.3 with urolithiasis in Chinese Han population. We performed case-control association analysis using 624 patients with nephrolithiasis and 1008 control subjects. We selected single-nucleotide polymorphism (SNPs) including rs12654812 and rs11746443 from 5q32.3; rs12669187 and rs1000597 from 7q14.3; rs7981733, rs4142110 and rs17646069 from 13q14.1 and rs4293393 from 16p12.3 which were previously reported to be associated with nephrolithiasis...
March 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28349055/antiurolithiasis-activity-of-bioactivity-guided-fraction-of-bergenia-ligulata-against-ethylene-glycol-induced-renal-calculi-in-rat
#17
Ikshit Sharma, Washim Khan, Rabea Parveen, Md Javed Alam, Iftekhar Ahmad, Mohd Hafizur Rehman Ansari, Sayeed Ahmad
Dried rhizome of Bergenia ligulata (pashanbhed) is commonly used as a traditional herbal medicine with a wide range of therapeutic applications including urolithiasis. Aqueous extract of B. ligulata was prepared through maceration followed by decoction (mother extract, 35.9% w/w). Further, polarity based fractions were prepared successively from mother extract which yielded 3.4, 2.9, 5.4, 7.5, and 11.3% w/w of hexane, toluene, dichloromethane (DCM), n-butanol, and water fractions, respectively. The in vitro, ex vivo, and real-time antiurolithiasis activity of mother extract and fractions were carried out using aggregation assay in synthetic urine and in rat plasma...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28335477/association-between-circulating-vitamin-d-level-and-urolithiasis-a-systematic-review-and-meta-analysis
#18
REVIEW
Henglong Hu, Jiaqiao Zhang, Yuchao Lu, Zongbiao Zhang, Baolong Qin, Hongbin Gao, Yufeng Wang, Jianning Zhu, Qing Wang, Yunpeng Zhu, Yang Xun, Shaogang Wang
Many studies compared the serum/plasma 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D) and 25 hydroxyvitamin D₃ (25(OH)D) between people with and without nephrolithiasis, and their results were conflicting. After systematically searching PubMed, Web of Science, The Cochrane Library, CNKI, and the Wanfang Database, we conducted a meta-analysis. Thirty-two observational studies involving 23,228 participants were included. Meta-analysis of these studies showed that of stone formers (SFs), calcium SFs had significantly higher concentrations of 1,25(OH)₂D (weighted mean difference (WMD), 10...
March 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28324150/stress-stones-stress-recurrent-stones-a-self-propagating-cycle-difficulties-in-solving-this-dichotomy
#19
Montserrat Arzoz-Fabregas, Josep Roca-Antonio, Luis Ibarz-Servio, Dalielah Jappie-Mahomed, Allen Rodgers
Numerous studies have reported an association between stress and urolithiasis. Although urinary risk factors have been measured in several of these, compelling evidence of a causal relationship has not been established. A shortcoming is that alterations in single urinary parameters rather than ratios and quotients, which provide a more synergistic risk evaluation, have been measured. Recently, we speculated about a possible association between chronic stress and stone recurrence. This presents an intriguing dichotomy of whether stress causes stones or vice versa, or whether they are linked in a self-propagating stress-stones-stress-recurrence cycle...
March 21, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28291706/medical-expulsive-therapy-use-in-emergency-department-patients-diagnosed-with-ureteral-stones
#20
Ralph C Wang, Newton Addo, Thomas Chi, Christopher Moore, Michael Mallin, Stephen Shiboski, Marshall Stoller, Rebecca Smith-Bindman
OBJECTIVE: Recent studies have clarified the role of alpha-blockers, such as tamsulosin, for patients diagnosed with ureteral stones <10mm not requiring an urgent intervention. Prior studies have reported low rates of use of MET by emergency physicians. We sought to describe patterns of alpha-blocker use and to determine factors associated with utilization in patients diagnosed with ureterolithiasis in the ED. METHODS: We used data from a randomized trial of CT scan vs...
February 28, 2017: American Journal of Emergency Medicine
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