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https://www.readbyqxmd.com/read/24079411/cost-effectiveness-of-endoscopic-surveillance-of-non-dysplastic-barrett-s-esophagus
#1
Louisa G Gordon, George C Mayne, Nicholas G Hirst, Timothy Bright, David C Whiteman, David I Watson
BACKGROUND: Endoscopic surveillance for non-dysplastic Barrett's esophagus (BE) is contentious and its cost effectiveness unclear. OBJECTIVE: To perform an economic analysis of endoscopic surveillance strategies. DESIGN: Cost-utility analysis by using a simulation Markov model to synthesize evidence from large epidemiologic studies and clinical data for surveillance, based on international guidelines, applied in a coordinator-managed surveillance program...
February 2014: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/22624551/recent-developments-in-gastroesophageal-reflux-disease-and-barrett-s-esophagus-anno-2012
#2
REVIEW
Guido N J Tytgat
The incidence of gastroesophageal reflux disease (GERD) and esophageal columnar metaplasia is rising worldwide. Both mechanical and functional factors perturb the double sphincter barrier at the esophagogastric junction (EGJ). Discovery of the acid pocket is fundamental in understanding postprandial acid reflux. Adding impedencemetry to pH measurements allows detection of non-acid or weakly acidic reflux. Histologic and endoscopic injury of the squamous mucosa rises from dilation of the intercellular spaces, papillary extension, accentuated intrapapillary looping, red streaks, erosive tissue loss, etc...
June 2012: Journal of Digestive Diseases
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