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Barrett and surgery

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https://www.readbyqxmd.com/read/28328555/association-of-pediatric-cardiac-surgical-volume-and-mortality-after-cardiac-ecmo
#1
Cindy S Barrett, Titus T Chan, Jacob Wilkes, Susan L Bratton, Ravi R Thiagarajan
Centers with higher surgical and ECMO volume have improved survival for children undergoing pediatric cardiac surgery and ECMO respectively. We examined the relationship between both cardiac surgical and cardiac ECMO volumes, with survival. Using data from the Pediatric Health Information System, we reviewed patients who underwent ECMO during the hospitalization for cardiac surgery or heart transplantation from January 2003- June 2014. Among 106,967 patients in 43 centers undergoing a Risk Adjustment for Congenital Heart Surgery-1 (RACHS) 1-6 procedure (n =104,951) and/or cardiac transplantation (n=2016), 2...
March 20, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28326425/bilateral-pelvic-discontinuity-a-unique-condition-characterized-by%C3%A2-high-failure-rates-of-current-treatment
#2
John R Martin, Ian Barrett, Rafael J Sierra, David G Lewallen, Daniel J Berry
BACKGROUND: Bilateral pelvic discontinuity is characterized by complete dissociation of the superior and inferior pelvis secondary to bone loss or fracture. The end result is a freely mobile inferior pelvis at the level of each discontinuity which presents a significant reconstruction challenge. This clinical entity has not been described previously, and the results of surgical treatment are not known. METHODS: We retrospectively reviewed all identified cases of pelvic discontinuity (PD) treated with revision THA at one institution...
December 2016: Arthroplasty Today
https://www.readbyqxmd.com/read/28325198/the-evaluation-and-management-of-suspicious-gastric-lesions-following-bariatric-surgery
#3
REVIEW
Guillermo Gomez
Obesity has reached epidemic proportions worldwide and is associated with a higher mortality from several diseases, including adenocarcinoma of the esophagus and of the gastric cardia. Increased body mass index is associated with an increased incidence of gastroesophageal reflux disease (GERD), Barrett metaplasia, and adenocarcinoma of the cardia. Bariatric surgery remains the most effective therapy for morbid obesity and has the potential to improve weight-related GERD. A high index of suspicion is paramount for early detection of foregut neoplasia after bariatric surgery...
April 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28317452/recent-advances-in-diagnostic-testing-for-gastroesophageal-reflux-disease
#4
Rishi D Naik, Michael F Vaezi
Gastroesophageal reflux disease (GERD) has a large economic burden with important complications that include esophagitis, Barrett's esophagus, and adenocarcinoma. Despite endoscopy, validated patient questionnaires, and traditional ambulatory pH monitoring, the diagnosis of GERD continues to be challenging. Areas covered: This review will explore the difficulties in diagnosing GERD with a focus on new developments, ranging from basic fundamental changes (histology and immunohistochemistry) to direct patient care (narrow-band imaging, impedance, and response to anti-reflux surgery)...
March 20, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28302078/early-serum-creatinine-accurately-predicts-acute-kidney-injury-post-cardiac-surgery
#5
Keren Grynberg, Kevan R Polkinghorne, Sharon Ford, Fiona Stenning, Thomas E Lew, Jonathan A Barrett, Shaun A Summers
BACKGROUND: Acute Kidney Injury (AKI) is a well recognized complication of cardiac surgery. It is associated with significant morbidity and mortality. The aims of our study are twofold; 1. To define the incidence of AKI post cardiac surgery. 2. To identify pre-morbid and operative risk factors for developing AKI and to determine if immediate post operative serum creatinine (IPOsCr) accurately predicts the development of AKI. METHODS: We prospectively studied 196 consecutive patients undergoing elective (on-pump) cardiac surgery...
March 16, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28284654/validation-of-a-web-based-curriculum-for-resident-education-in-orthopedic-surgery-j-surg-educ-2016-1060-65
#6
Barrett Boody, Patrick Johnston, Andrew Pugely, Daniel Miller, Jeffrey Geller, William Payne, James Boegener, Michael Schafer, Matthew Beal
No abstract text is available yet for this article.
March 8, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28275832/endoscopic-treatment-of-high-grade-dysplasia-and-early-esophageal-cancer
#7
Francisco Schlottmann, Marco G Patti, Nicholas J Shaheen
BACKGROUND: The emergence of novel endoscopic modalities has challenged the role of surgery for patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD) or early esophageal adenocarcinoma. AIM: The aim of this study was to review the available evidence of the endoscopic treatment of HGD and early esopahgeal adenocarcinoma. RESULTS: For most patients with BE and HGD, endoscopic ablative therapy is the preferred treatment strategy...
March 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28258457/from-heartburn-to-barrett-s-esophagus-and-beyond
#8
Francisco Schlottmann, Marco G Patti, Nicholas J Shaheen
BACKGROUND: Gastroesophageal reflux disease (GERD) affects an estimated 20% of the population in the USA, and its prevalence is increasing worldwide. About 10-15% of patients with GERD will develop Barrett's esophagus (BE). AIMS: The aims of this study were to review the available evidence of the pathophysiology of BE and the role of anti-reflux surgery in the treatment of this disease. RESULTS: The transformation of the squamous epithelium into columnar epithelium with goblet cells is due to the chronic injury produced by repeated reflux episodes...
March 3, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28258451/surgical-treatment-of-high-grade-dysplasia-and-early-esophageal-cancer
#9
Patrick J McLaren, James P Dolan
BACKGROUND: The treatment of early-stage esophageal cancer and high-grade dysplasia of the esophagus has changed significantly in recent years. Many early tumors that were traditionally treated with esophagectomy can now be resected with endoscopic therapy alone. These new endoscopic modalities can offer similar survival outcomes without the associated morbidity of a major operation. However, a number of these cases may still require surgical intervention as the best treatment option...
March 3, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28242319/white-paper-aga-power-practice-guide-on-obesity-and%C3%A2-weight-management-education-and-resources
#10
REVIEW
Andres Acosta, Sarah Streett, Mathew D Kroh, Lawrence J Cheskin, Katherine H Saunders, Marina Kurian, Marsha Schofield, Sarah E Barlow, Louis Aronne
The epidemic of obesity continues at alarming rates, with a high burden to our economy and society. The American Gastroenterological Association understands the importance of embracing obesity as a chronic, relapsing disease and supports a multidisciplinary approach to the management of obesity. Because gastrointestinal disorders resulting from obesity are more frequent and often present sooner than type 2 diabetes mellitus and cardiovascular disease, gastroenterologists have an opportunity to address obesity and provide an effective therapy early...
February 24, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28235646/identifying-adverse-events-in-pediatric-surgery-comparing-morbidity-and-mortality-conference-with-the-nsqip-pediatric-system
#11
Barrett P Cromeens, Richard E Lisciandro, Richard J Brilli, Johanna R Askegard-Giesmann, Brian D Kenney, Gail E Besner
BACKGROUND: Recent improvements to morbidity and mortality (M&M) conference have focused on the case review system. However, case selection occurs by physician reporting, which is limited by selection bias. We compared the effectiveness of our M&M conference with the NSQIP-Pediatric (NSQIP-P) system for identifying adverse events. STUDY DESIGN: Complications from January 2010 to September 2015 were compared between M&M and NSQIP-P. Only M&M patients meeting NSQIP-P criteria were compared with patients from the NSQIP-P system; exclusions were studied separately...
February 22, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28205007/long-term-evaluation-of-biliary-reflux-after-experimental-one-anastomosis-gastric-bypass-in-rats
#12
Matthieu Bruzzi, Henri Duboc, Caroline Gronnier, Dominique Rainteau, Anne Couvelard, Maude Le Gall, André Bado, Jean-Marc Chevallier
BACKGROUND: Controversy remains regarding biliary reflux after one-anastomosis gastric bypass (OAGB). The aim of this "pilot" study was to analyze biliary reflux and its potential long-term consequences on esogastric mucosae in OAGB-operated rats. METHODS: Diet-induced obese rats were subjected to OAGB (n = 10) or sham (n = 4) surgery and followed up for 16 weeks. Evolution of weight and glucose tolerance was analyzed. Bile acid concentration measurement, histological and qRT-PCR analysis were performed in the esogastric segments...
February 15, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28159540/complex-early-barrett-s-neoplasia-at-3-western-centers-european-barrett-s-endoscopic-submucosal-dissection-trial-e-best
#13
Sharmila Subramaniam, Fergus Chedgy, Gaius Longcroft Wheaton, Kesavan Kandiah, Roberta Maselli, Stefan Seewald, Alessandro Repici, Pradeep Bhandari
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is an effective technique to resect early Barrett's neoplasia and has advantages over conventional endoscopic mucosal resection (EMR) as it enables en bloc resection and accurate histopathological analysis of cancer resection margins. However, its long learning curve and higher adverse event rate has tempered its uptake in the West. We aimed to analyze the safety and efficacy of ESD when used to resect complex Barrett's neoplasia...
January 31, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28122386/endoscopic-management-of-barrett-s-esophagus-european-society-of-gastrointestinal-endoscopy-esge-position-statement
#14
Bas Weusten, Raf Bisschops, Emanuel Coron, Mário Dinis-Ribeiro, Jean-Marc Dumonceau, José-Miguel Esteban, Cesare Hassan, Oliver Pech, Alessandro Repici, Jacques Bergman, Massimiliano di Pietro
Current practices for the management of Barrett's esophagus (BE) vary across Europe, as several national European guidelines exist. This Position Statement from the European Society of Gastrointestinal Endoscopy (ESGE) is an attempt to homogenize recommendations and, hence, patient management according to the best scientific evidence and other considerations (e.g. health policy). A Working Group developed consensus statements, using the existing national guidelines as a starting point and considering new evidence in the literature...
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28052866/renal-denervation-in-male-rats-with-heart-failure-improves-ventricular-sympathetic-nerve-innervation-and-function
#15
Maximilian Ichabod Pinkham, Michael T Loftus, Satya Amirapu, Sarah-Jane Guild, Gina Quill, William R Woodward, Beth A Habecker, Carolyn J Barrett
Heart failure is characterized by the loss of sympathetic innervation to the ventricles, contributing to impaired cardiac function and arrhythmogenesis. We hypothesized that renal denervation (RDx) would reverse this loss. Male Wistar rats underwent myocardial infarction (MI) or sham surgery and progressed into heart failure for four weeks before receiving bilateral RDx or sham RDx. After a further three weeks, left ventricular (LV) function was assessed and ventricular sympathetic nerve fibre density determined via histology...
January 4, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28042960/squamous-cell-carcinoma-antigen-scca-is-up-regulated-during-barrett-s-carcinogenesis-and-predicts-esophageal-adenocarcinoma-resistance-to-neoadjuvant-chemotherapy
#16
Matteo Fassan, Stefano Realdon, Luca Vianello, Santina Quarta, Alberto Ruol, Carlo Castoro, Marco Scarpa, Giovanni Zaninotto, Vincenza Guzzardo, Vanna Chiarion Sileni, Patrizia Pontisso, Massimo Rugge
Squamous Cell Carcinoma Antigen (SCCA) is consistently overexpressed in many different solid tumors, and has been associated with both tumor aggressiveness and chemoresistance. No data, however, is currently available on SCCA expression during esophageal Barrett's carcinogenesis, nor on SCCA expression's role on esophageal adenocarcinoma chemoresistance. The SCCA immunohistochemical expression was assessed in a series of 100 biopsy samples covering the whole histological spectrum of Barrett's oncogenesis. Squamous native mucosa was characterized by a moderate to strong cytoplasmic and nuclear SCCA expression in suprabasal, medium, and superficial layers...
December 22, 2016: Oncotarget
https://www.readbyqxmd.com/read/28027257/evidence-based-medicine-reduction-mammaplasty
#17
Richard Greco, Barrett Noone
LEARNING OBJECTIVES: After reading this article, the participant should be able to: 1. Understand the multiple reduction mammaplasty techniques available for patients and describe the advantages and disadvantages associated with each. 2. Describe the indications for the treatment of macromastia in patients younger than 18 years. 3. Identify the preoperative indications for breast imaging before surgery. 4. Describe the benefits of breast infiltration with local anesthesia with epinephrine before surgery...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27996337/steady-state-energy-balance-in-animal-models-of-obesity-and-weight-loss
#18
Magnus Kringstad Olsen, Helene Johannessen, Nikki Cassie, Perry Barrett, Koji Takeuchi, Bård Kulseng, Duan Chen, Chun-Mei Zhao
OBJECTIVE: We wanted to exam the steady-state energy balance by using high-fat diet-induced obese (DIO) rats and mice as models for positive energy balance, and gastric bypassed (GB) rats and gene knockout of muscarinic acetylcholine M3 receptor (M3KO) mice as models for negative energy balance. METHODS: One hundred and thirty-two rats and mice were used. Energy balance was measured by a comprehensive laboratory animal monitoring system. Gene expression was analysed by in situ hybridisation in M3KO mice...
April 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27995191/non-radical-stepwise-complete-endoscopic-resection-of-barrett-s-epithelium-in-short-segment-barrett-s-esophagus-has-a-low-stricture-rate
#19
Andreas Koutsoumpas, Lai Mun Wang, Adam A Bailey, Richard Gillies, Robert Marshall, Michael Booth, Bruno Sgromo, Nick Maynard, Barbara Braden
Background and aims: Radical endoscopic excision of Barrett's epithelium performing 4 - 6 endoscopic resections during the same endoscopic session results in complete Barrett's eradication but has a high stricture rate (40 - 80 %). Therefore radiofrequency ablation is preferred after endoscopic mucosal resection (EMR) of visible nodules. We investigated the clinical outcome of non-radical, stepwise endoscopic mucosal resection with a maximum of two endoscopic resections per endoscopic session. Methods: We analysed our prospectively maintained database of patients undergoing esophageal EMR for early neoplasia in Barrett's esophagus from 2009 to 2014...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27978587/efficacy-of-two-techniques-in-anterior-cruciate-ligament-reconstruction
#20
James A Hurt, John H Berry, William Replogle, Kasey Thibodeaux, Josie M Hydrick, Austin M Barrett, Gene R Barrett
The purpose of this study is to compare failure rate and functional outcome in young, active patients (< 25 years) with two-incision (rear-entry) versus transtibial (all-endoscopic) anterior cruciate ligament (ACL) reconstructions.Utilizing a computerized relational database (Access 2007, Microsoft Inc., Redmond, WA), 480 patients were identified that underwent ACL reconstruction, using a bone-patellar-tendon-bone autograft, by a single surgeon between January 2000 and December 2010 via a transtibial or two-incision technique...
December 15, 2016: Journal of Knee Surgery
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