keyword
https://read.qxmd.com/read/38648857/aapm-task-group-334-a-guidance-document-to-using-radiotherapy-immobilization-devices-and-accessories-in-an-mr-environment
#1
JOURNAL ARTICLE
Maritza A Hobson, Yanle Hu, Barrett Caldwell, Gil'ad N Cohen, Carri Glide-Hurst, Long Huang, Paul D Jackson, Sunyoung Jang, Ulrich Langner, Hannah J Lee, Ives R Levesque, Sreeram Narayanan, Justin C Park, John Steffen, Q Jackie Wu, Yong Zhou
Use of magnetic resonance (MR) imaging in radiation therapy has increased substantially in recent years as more radiotherapy centers are having MR simulators installed, requesting more time on clinical diagnostic MR systems, or even treating with combination MR linear accelerator (MR-linac) systems. With this increased use, to ensure the most accurate integration of images into radiotherapy (RT), RT immobilization devices and accessories must be able to be used safely in the MR environment and produce minimal perturbations...
April 22, 2024: Medical Physics
https://read.qxmd.com/read/38636819/computer-aided-diagnosis-improves-characterization-of-barrett-s-neoplasia-by-general-endoscopists
#2
JOURNAL ARTICLE
Jelmer B Jukema, Carolus H J Kusters, Martijn R Jong, Kiki N Fockens, Tim Boers, Joost A van der Putten, Roos E Pouw, Lucas C Duits, BasL A M Weusten, Lorenza Alvarez Herrero, Martin H M G Houben, Wouter B Nagengast, Jessie Westerhof, Alaa Alkhalaf, Rosalie Mallant-Hent, Pieter Scholten, Krish Ragunath, Stefan Seewald, Peter Elbe, Francisco Baldaque Silva, Maximilien Barret, Jacobo Ortiz Fernández-Sordo, Guiomar Moral Villarejo, Oliver Pech, Torsten Beyna, Nahid S M Montazeri, Fons van der Sommen, Peter H de With, A Jeroen de Groof, Jacques J Bergman
BACKGROUND & AIMS: Characterization of visible abnormalities in Barrett esophagus (BE) patients can be challenging, especially for unexperienced endoscopists. This results in suboptimal diagnostic accuracy and poor inter-observer agreement. Computer-aided diagnosis (CADx) systems may assist endoscopists. We aimed to develop, validate and benchmark a CADx system for BE neoplasia. METHODS: The CADx system received pretraining with ImageNet with consecutive domain-specific pretraining with GastroNet which includes 5 million endoscopic images...
April 16, 2024: Gastrointestinal Endoscopy
https://read.qxmd.com/read/38636509/genomic-answers-for-kids-toward-more-equitable-access-to-genomic-testing-for-rare-diseases-in-rural-populations
#3
REVIEW
Ana S A Cohen, Courtney D Berrios, Tricia N Zion, Cassandra M Barrett, Riley Moore, Emelia Boillat, Bradley Belden, Emily G Farrow, Isabelle Thiffault, Britton D Zuccarelli, Tomi Pastinen
Next-generation sequencing has revolutionized the speed of rare disease (RD) diagnoses. While clinical exome and genome sequencing represent an effective tool for many RD diagnoses, there is room to further improve the diagnostic odyssey of many RD patients. One recognizable intervention lies in increasing equitable access to genomic testing. Rural communities represent a significant portion of underserved and underrepresented individuals facing additional barriers to diagnosis and treatment. Primary care providers (PCPs) at local clinics, though sometimes suspicious of a potential benefit of genetic testing for their patients, have significant constraints in pursuing it themselves and rely on referrals to specialists...
April 10, 2024: American Journal of Human Genetics
https://read.qxmd.com/read/38611688/utility-of-dual-energy-computed-tomography-in-clinical-conundra
#4
REVIEW
Ahmad Abu-Omar, Nicolas Murray, Ismail T Ali, Faisal Khosa, Sarah Barrett, Adnan Sheikh, Savvas Nicolaou, Stefania Tamburrini, Francesca Iacobellis, Giacomo Sica, Vincenza Granata, Luca Saba, Salvatore Masala, Mariano Scaglione
Advancing medical technology revolutionizes our ability to diagnose various disease processes. Conventional Single-Energy Computed Tomography (SECT) has multiple inherent limitations for providing definite diagnoses in certain clinical contexts. Dual-Energy Computed Tomography (DECT) has been in use since 2006 and has constantly evolved providing various applications to assist radiologists in reaching certain diagnoses SECT is rather unable to identify. DECT may also complement the role of SECT by supporting radiologists to confidently make diagnoses in certain clinically challenging scenarios...
April 7, 2024: Diagnostics
https://read.qxmd.com/read/38610762/development-of-an-artificial-intelligence-diagnostic-system-using-linked-color-imaging-for-barrett-s-esophagus
#5
JOURNAL ARTICLE
Tsutomu Takeda, Daisuke Asaoka, Hiroya Ueyama, Daiki Abe, Maiko Suzuki, Yoshihiro Inami, Yasuko Uemura, Momoko Yamamoto, Tomoyo Iwano, Ryota Uchida, Hisanori Utsunomiya, Shotaro Oki, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kohei Matsumoto, Kumiko Ueda, Mariko Hojo, Shuko Nojiri, Tomohiro Tada, Akihito Nagahara
Background: Barrett's esophagus and esophageal adenocarcinoma cases are increasing as gastroesophageal reflux disease increases. Using artificial intelligence (AI) and linked color imaging (LCI), our aim was to establish a method of diagnosis for short-segment Barrett's esophagus (SSBE). Methods: We retrospectively selected 624 consecutive patients in total at our hospital, treated between May 2017 and March 2020, who experienced an esophagogastroduodenoscopy with white light imaging (WLI) and LCI. Images were randomly chosen as data for learning from WLI: 542 (SSBE+/- 348/194) of 696 (SSBE+/- 444/252); and LCI: 643 (SSBE+/- 446/197) of 805 (SSBE+/- 543/262)...
March 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38606865/global-practice-patterns-in-the-evaluation-of-non-obstructive-azoospermia-results-of-a-world-wide-survey-and-expert-recommendations
#6
JOURNAL ARTICLE
Rupin Shah, Amarnath Rambhatla, Widi Atmoko, Marlon Martinez, Imad Ziouziou, Priyank Kothari, Nicholas Tadros, Nguyen Ho Vinh Phuoc, Parviz Kavoussi, Ahmed Harraz, Gianmaria Salvio, Murat Gul, Taha Hamoda, Tuncay Toprak, Ponco Birowo, Edmund Ko, Mohamed Arafa, Ramy Abou Ghayda, Vilvapathy Senguttuvan Karthikeyan, Ramadan Saleh, Giorgio Ivan Russo, Germar-Michael Pinggera, Eric Chung, Missy Savira, Giovanni M Colpi, Wael Zohdy, Edoardo Pescatori, Hyun Jun Park, Shinichiro Fukuhara, Akira Tsujimura, Cesar Rojas-Cruz, Angelo Marino, Siu King Mak, Edouard Amar, Wael Ibrahim, Puneet Sindhwani, Naif Alhathal, Gian Maria Busetto, Manaf Al Hashimi, Ahmed El-Sakka, Asci Ramazan, Fotios Dimitriadis, Massimiliano Timpano, Davor Jezek, Baris Altay, Daniel Suslik Zylbersztejn, Michael Yc Wong, Du Geon Moon, Christine Wyns, Safar Gamidov, Hamed Akhavizadegan, Alessandro Franceschelli, Kaan Aydos, Vinh Nguyen Quang, Shedeed Ashour, Adel Al Dayel, Mohamed S Al-Marhoon, Sava Micic, Saleh Binsaleh, Alayman Hussein, Haitham Elbardisi, Taymour Mostafa, Emad Taha, Jonathan Ramsay, Athanasios Zachariou, Islam Fathy Soliman Abdelrahman, Osvaldo Rajmil, Arif Kalkanli, Juan Manuel Corral Molina, Kadir Bocu, Gede Wirya Kusuma Duarsa, Gokhan Ceker, Ege Can Serefoglu, Fahmi Bahar, Nazim Gherabi, Shinnosuke Kuroda, Abderrazak Bouzouita, Ahmet Gudeloglu, Erman Ceyhan, Mohamed Saeed Mohamed Hasan, Muhammad Ujudud Musa, Ahmad Motawi, Cho Chak-Lam, Hisanori Taniguchi, Christopher Chee Kong Ho, Jesus Fernando Solorzano Vazquez, Shingai Mutambirwa, Nur Dokuzeylul Gungor, Marion Bendayan, Carlo Giulioni, Aykut Baser, Marco Falcone, Luca Boeri, Gideon Blecher, Alireza Kheradmand, Tamilselvi Sethupathy, Ricky Adriansjah, Nima Narimani, Charalampos Konstantinidis, Tuan Thanh Nguyen, Andrian Japari, Parisa Dolati, Keerti Singh, Cevahir Ozer, Selcuk Sarikaya, Nadia Sheibak, Ndagijimana Jean Bosco, Mehmet Serkan Özkent, Sang Thanh Le, Ioannis Sokolakis, Darren Katz, Ryan Smith, Manh Nguyen Truong, Tan V Le, Zhongwei Huang, Muslim Dogan Deger, Umut Arslan, Gokhan Calik, Giorgio Franco, Ayman Rashed, Oguzhan Kahraman, Sotiris Andreadakis, Rosadi Putra, Giancarlo Balercia, Kareim Khalafalla, Rossella Cannarella, Anh Ðăng Tuân, Amr El Meliegy, Birute Zilaitiene, Marlene Lizbeth Zamora Ramirez, Filippo Giacone, Aldo E Calogero, Konstantinos Makarounis, Sunil Jindal, Bac Nguyen Hoai, Ravi Banthia, Marcelo Rodriguez Peña, Dharani Moorthy, Aram Adamyan, Deniz Kulaksiz, Hussein Kandil, Nikolaos Sofikitis, Ciro Salzano, Andreas Jungwirth, Surendra Reddy Banka, Tiago Cesar Mierzwa, Tahsin Turunç, Divyanu Jain, Armen Avoyan, Pietro Salacone, Ateş Kadıoğlu, Chirag Gupta, Haocheng Lin, Iman Shamohammadi, Nasser Mogharabian, Trenton Barrett, Yavuz Onur Danacıoğlu, Andrea Crafa, Salima Daoud, Vineet Malhotra, Abdulmalik Almardawi, Osama Mohamed Selim, Mohamad Moussa, Saeid Haghdani, Mesut Berkan Duran, Yannic Kunz, Mirko Preto, Elena Eugeni, Thang Nguyen, Ahmed Rashad Elshahid, Seso Sulijaya Suyono, Dyandra Parikesit, Essam Nada, Eduardo Gutiérrez Orozco, Florence Boitrelle, Nguyen Thi Minh Trang, Mounir Jamali, Raju Nair, Mikhail Ruzaev, Franco Gadda, Charalampos Thomas, Raphael Henrique Ferreira, Umit Gul, Serena Maruccia, Ajay Kanbur, Ella Kinzikeeva, Saad Abumelha, Nguyen Quang, Raghavender Kosgi, Fatih Gokalp, Mohammad Ayodhia Soebadi, Gustavo Marquesine Paul, Hesamoddin Sajadi, Deepak Gupte, Rafael F Ambar, Emrullah Sogutdelen, Karun Singla, Ari Basurkano, Shannon Hee Kyung Kim, Mohammad Ali Sadighi Gilani, Koichi Nagao, Sakti Ronggowardhana Brodjonegoro, Andri Rezano, Mohamed Elkhouly, Rossella Mazzilli, Hasan M A Farsi, Hung Nguyen Ba, Hamed Alali, Dimitrios Kafetzis, Tran Quang Tien Long, Sami Alsaid, Hoang Bao Ngoc Cuong, Knigavko Oleksandr, Akhmad Mustafa, Herik Acosta, Hrishikesh Pai, Bahadır Şahin, Eko Arianto, Colin Teo, Sanjay Prakash Jayaprakash, Rinaldo Indra Rachman, Mustafa Gurkan Yenice, Omar Sefrioui, Smit Paghdar, Shivam Priyadarshi, Marko Tanic, Noor Kareem Alfatlawy, Fikri Rizaldi, Ranjit B Vishwakarma, George Kanakis, Dinesh Thomas Cherian, Joe Lee, Raisa Galstyan, Hakan Keskin, Jana Wurzacher, Doddy Hami Seno, Bambang S Noegroho, Ria Margiana, Qaisar Javed, Fabrizio Castiglioni, Raman Tanwar, Ana Puigvert, Coşkun Kaya, Medianto Purnomo, Chadi Yazbeck, Azwar Amir, Edson Borges, Marina Bellavia, Isaac Ardianson Deswanto, Vinod K V, Giovanni Liguori, Dang Hoang Minh, Kashif Siddiqi, Fulvio Colombo, Armand Zini, Niket Patel, Selahittin Çayan, Ula Al-Kawaz, Maged Ragab, Charalampos Konstantinidis, Guadalupe Hernández Hebrard, Ivan Hoffmann, Ozan Efesoy, Barış Saylam, Ashok Agarwal
PURPOSE: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, comparing them with guidelines and offering expert recommendations. MATERIALS AND METHODS: A 56-item questionnaire survey on NOA diagnosis and management was conducted globally from July to September 2022. This paper focuses on part 1, evaluating NOA diagnosis...
April 3, 2024: World Journal of Men's Health
https://read.qxmd.com/read/38604297/the-use-of-a-real-time-computer-aided-detection-system-for-visible-lesions-in-the-barrett-s-esophagus-during-live-endoscopic-procedures-a-pilot-study
#7
JOURNAL ARTICLE
Kiki N Fockens, Jelmer B Jukema, Martijn R Jong, Tim Boers, Joost A van der Putten, Carolus H J Kusters, Roos E Pouw, Lucas C Duits, Fons van der Sommen, Peter H de With, A Jeroen de Groof, Jacques J Bergman
BACKGROUND AND AIMS: In this pilot study we evaluated performance of a recently developed computer-aided detection (CADe) system for Barrett's neoplasia during live endoscopic procedures. METHODS: 15 patients with and 15 without a visible lesion were included in this study. A CAD assisted workflow was employed that included: a slow pullback video recording of the entire Barrett's segment with live CADe assistance, followed by CADe assisted level-based video recordings every 2cm of the Barrett's segment...
April 9, 2024: Gastrointestinal Endoscopy
https://read.qxmd.com/read/38601005/potential-value-of-a-rapid-syndromic-multiplex-pcr-for-the-diagnosis-of-native-and-prosthetic-joint-infections-a-real-world-evidence-study
#8
JOURNAL ARTICLE
Stéphanie Pascual, Brooklyn Noble, Nusreen Ahmad-Saeed, Catherine Aldridge, Simone Ambretti, Sharon Amit, Rachel Annett, Shaan Ashk O'Shea, Anna Maria Barbui, Gavin Barlow, Lucinda Barrett, Mario Berth, Alessandro Bondi, Nicola Boran, Sara E Boyd, Catarina Chaves, Martin Clauss, Peter Davies, Ileana T Dianzo-Delgado, Jaime Esteban, Stefan Fuchs, Lennart Friis-Hansen, Daniel Goldenberger, Andrej Golle, Juha O Groonroos, Ines Hoffmann, Tomer Hoffmann, Harriet Hughes, Marina Ivanova, Peter Jezek, Gwennan Jones, Zeynep Ceren Karahan, Cornelia Lass-Flörl, Frédéric Laurent, Laura Leach, Matilde Lee Horsbøll Pedersen, Caroline Loiez, Maureen Lynch, Robert J Maloney, Martin Marsh, Olivia Milburn, Shanine Mitchell, Luke S P Moore, Lynn Moffat, Marianna Murdjeva, Michael E Murphy, Deepa Nayar, Giacomo Nigrisoli, Fionnuala O'Sullivan, Büşra Öz, Teresa Peach, Christina Petridou, Mojgan Prinz, Mitja Rak, Niamh Reidy, Gian Maria Rossolini, Anne-Laure Roux, Patricia Ruiz-Garbajosa, Kordo Saeed, Llanos Salar-Vidal, Carlos Salas Venero, Mathyruban Selvaratnam, Eric Senneville, Peter Starzengruber, Ben Talbot, Vanessa Taylor, Rihard Trebše, Deborah Wearmouth, Birgit Willinger, Marjan Wouthuyzen-Bakker, Brianne Couturier, Florence Allantaz
Introduction : The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint infections (PJIs). Methods : A study was conducted across 34 clinical sites in 19 European and Middle Eastern countries from March 2021 to June 2022 to assess the effectiveness of the BIOFIRE JI Panel. Results : A total of 1527 samples were collected from patients suspected of SA or PJI, with an overall agreement of 88...
2024: Journal of Bone and Joint Infection
https://read.qxmd.com/read/38585417/deep-learning-based-image-super-resolution-of-an-end-expandable-optical-fiber-probe-for-application-in-esophageal-cancer-diagnostics
#9
JOURNAL ARTICLE
Xiaohui Zhang, Mimi Tan, Mansour Nabil, Richa Shukla, Shaleen Vasavada, Sharmila Anandasabapathy, Mark A Anastasio, Elena Petrova
SIGNIFICANCE: Endoscopic screening for esophageal cancer (EC) may enable early cancer diagnosis and treatment. While optical microendoscopic technology has shown promise in improving specificity, the limited field of view (<mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo><</mml:mo><mml:mn>1</mml:mn><mml:mtext>  </mml:mtext><mml:mi>mm</mml:mi></mml:mrow></mml:math>) significantly reduces the ability to survey large areas efficiently in EC screening...
April 2024: Journal of Biomedical Optics
https://read.qxmd.com/read/38583873/anaesthesia-related-morbidity-associated-with-recumbent-low-field-magnetic-resonance-imaging-of-horses
#10
JOURNAL ARTICLE
M G Myhre, A Azeem, M Barrett
CASE HISTORY: Medical records from 2009 to 2021 from a private equine referral hospital in Rochester, NH, USA were analysed for cases that underwent general anaesthesia for low-field MRI of the distal limb. These were used to determine peri-anaesthetic morbidity and mortality. CLINICAL FINDINGS AND OUTCOME: Two hundred and forty-three anaesthetic episodes were recorded in horses undergoing low-field MRI. The peri-anaesthetic complication rate prior to discharge was 6...
May 2024: New Zealand Veterinary Journal
https://read.qxmd.com/read/38582609/esophagogastroduodenoscopy-findings-that-do-no-not-explain-dysphagia-are-associated-with-underutilization-of-high-resolution-manometry
#11
JOURNAL ARTICLE
Sydney Pomenti, John Nathanson, Meaghan Phipps, Chino Aneke-Nash, David Katzka, Daniel Freedberg, Daniela Jodorkovsky
In patients with dysphagia that is not explained by upper endoscopy, high-resolution esophageal manometry (HRM) is the next logical step in diagnostic testing. This study investigated predictors of failure to refer for HRM after an upper endoscopy that was performed for but did not explain dysphagia. This was a retrospective cohort study of patients >18 years of age who underwent esophagogastroduodenoscopy (EGD) for dysphagia from 2015 to 2021. Patients with EGD findings that explained dysphagia (e.g. esophageal mass, eosinophilic esophagitis, Schatzki ring, etc...
April 6, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38567975/taqman-pacman-a-simple-molecular-approach-for-positive-rapid-antigen-test-confirmation-during-periods-of-low-prevalence
#12
JOURNAL ARTICLE
Gregory R McCracken, Glenn Patriquin, Todd F Hatchette, Ross J Davidson, Barbara Goodall, Lisa Barrett, James MacDonald, Charles Heinstein, Janice Pettipas, John Ross, Jason J LeBlanc
UNLABELLED: Antigen-based rapid diagnostic tests (Ag-RDTs) were widely deployed to enhance SARS-CoV-2 testing capacity during the COVID-19 pandemic. Consistent with national guidance for low prevalence settings, positive Ag-RDTs were confirmed using nucleic acid amplification tests (NAATs) to avoid false positive results. However, increasing demands for positive Ag-RDT confirmation competed with other testing priorities in clinical laboratories. This work hypothesized that real-time RT-PCR without nucleic acid extraction (NAE) would be sufficiently sensitive to support positive Ag-RDT confirmation...
April 3, 2024: Microbiology Spectrum
https://read.qxmd.com/read/38563143/right-ventricular-function-on-cardiovascular-magnetic-resonance-imaging-and-long-term-outcomes-in-stable-heart-transplant-recipients
#13
JOURNAL ARTICLE
Collin M Barrett, Parag Bawaskar, Andrew Hughes, Pal Satyajit Singh Athwal, Yugene Guo, Tamas Alexy, Chetan Shenoy
BACKGROUND: In heart transplant recipients, right ventricular (RV) dysfunction may occur for a variety of reasons. Whether RV dysfunction in the stable phase after heart transplantation is associated with long-term adverse outcomes is unknown. We aimed to determine the long-term prognostic significance of RV dysfunction identified on cardiovascular magnetic resonance imaging (CMR) at least 1 year after heart transplantation. METHODS: In consecutive heart transplant recipients who underwent CMR for surveillance, we assessed 2 CMR measures of RV function: RV ejection fraction and RV global longitudinal strain (RVGLS)...
April 2, 2024: Circulation. Cardiovascular Imaging
https://read.qxmd.com/read/38547927/effect-of-ai-on-performance-of-endoscopists-to-detect-barrett-neoplasia-a-randomized-tandem-trial
#14
JOURNAL ARTICLE
Michael Meinikheim, Robert Mendel, Christoph Palm, Andreas Probst, Anna Muzalyova, Markus Wolfgang Scheppach, Sandra Nagl, Elisabeth Schnoy, Christoph Römmele, Dominik Andreas Helmut Otto Schulz, Jakob Schlottmann, Friederike Prinz, David Rauber, Tobias Rückert, Tomoaki Matsumura, Glòria Fernández-Esparrach, Nasim Parsa, Michael F Byrne, Helmut Messmann, Alanna Ebigbo
Background and study aims To evaluate the effect of an AI-based clinical decision support system (AI) on the performance and diagnostic confidence of endoscopists during the assessment of Barrett's esophagus (BE). Patients and Methods Ninety-six standardized endoscopy videos were assessed by 22 endoscopists from 12 different centers with varying degrees of BE experience. The assessment was randomized into two video sets: Group A (review first without AI and second with AI) and group B (review first with AI and second without AI)...
March 28, 2024: Endoscopy
https://read.qxmd.com/read/38545626/impact-of-the-emotional-development-approach-on-psychotropic-medication-in-adults-with-intellectual-and-developmental-disabilities-a-retrospective-clinical-analysis
#15
JOURNAL ARTICLE
B F Barrett, M Wehmeyer, J Kolb, T Ostermann, T Sappok
BACKGROUND: Compared with the general population, adults with an intellectual developmental disorder (IDD) are more likely to develop mental health problems and to receive high levels of psychotropic medication, particularly antipsychotics. The emotional development (ED) approach may help to better understand the nature of challenging behaviour (CB) and tailor treatment and support accordingly. The aim of this retrospective study was to investigate the impact of the ED approach on the prescription of psychotropic medication during inpatient psychiatric treatment...
March 28, 2024: Journal of Intellectual Disability Research: JIDR
https://read.qxmd.com/read/38524759/vaginal-calculus-formation-on-exposed-midurethral-sling-mesh
#16
Adam J Langer, Zenab Saeed, Elizabeth Barrett, Rose A Maxwell, David N Dhanraj, Geoffrey D Towers, Eyra A Agudu
The presence of a vaginal calculus is a rare clinical entity which may develop in the setting of vaginal urinary stagnation. Numerous factors contribute to stone formation, and management can be complicated by variations in size, location of the stone, and location of adjacent structures. Generally, once diagnosed, vaginal calculi should be removed and surrounding anatomy should be evaluated thoroughly for secondary fistula, erosion, or presence of an instituting foreign body. This report presents a case of vaginal calculus formation on exposed midurethral sling mesh in an elderly patient with hemorrhagic cystitis...
2024: Case Reports in Obstetrics and Gynecology
https://read.qxmd.com/read/38518703/esophageal-adenocarcinoma-heterogeneity-in-clinicopathology-and-prognosis-a-single-center-longitudinal-study-of-146-cases-over-a-20-year-period
#17
JOURNAL ARTICLE
Qin Huang, Edward Lew, Yuqing Cheng, Shweta Shinagare, Vikram Deshpande, Jason S Gold, Daniel Wiener, H Christian Weber
Recent genomic studies suggest that esophageal adenocarcinoma (EAC) is not homogeneous and can be divided into true (tEAC) and probable (pEAC) groups. We compared clinicopathologic and prognostic features between the two groups of EAC. Based on endoscopic, radiologic, surgical, and pathologic reports, tumors with epicenters beyond 2 cm of the gastroesophageal junction (GEJ) were assigned to the tEAC group (N = 63), while epicenters within 2 cm of, but not crossing the GEJ, were allocated to the pEAC group (N = 83)...
February 27, 2024: Annals of Diagnostic Pathology
https://read.qxmd.com/read/38509884/plant-mediated-biosynthesis-of-mn-3-o-4-nanostructures-and-their-biomedical-applications
#18
JOURNAL ARTICLE
Dalal N Binjawhar, Nouf M Al-Enazi, Khawla Alsamhary, Mansour Kha
Nanomaterials have drawn significant attention for their biomedical and pharmaceutical applications. In the present study, manganese tetra oxide (Mn3 O4 ) nanoparticles were prepared greenly, and their physicochemical properties were studied. Taxus baccata acetone extract was used as a safely novel precursor for reducing and stabilizing nanoparticles. The synthesized nanoparticles were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Brunauer-Emmett-Teller (BET), and Barrett-Joyner-Halenda (BJH) and X-ray diffraction (XRD)...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38503918/expect-the-unexpected-investigating-discordant-prostate-mri-and-biopsy-results
#19
JOURNAL ARTICLE
Arnaldo Stanzione, Kang-Lung Lee, Nimalan Sanmugalingam, Ishwariya Rajendran, Nikita Sushentsev, Iztok Caglič, Tristan Barrett
OBJECTIVES: To evaluate discrepant radio-pathological outcomes in biopsy-naïve patients undergoing prostate MRI and to provide insights into the underlying causes. MATERIALS AND METHODS: A retrospective analysis was conducted on 2780 biopsy-naïve patients undergoing prostate MRI at a tertiary referral centre between October 2015 and June 2022. Exclusion criteria were biopsy not performed, indeterminate MRI findings (PI-RADS 3), and clinically insignificant PCa (Gleason score 3 + 3)...
March 20, 2024: European Radiology
https://read.qxmd.com/read/38495690/next-generation-endoscopic-probe-for-detection-of-esophageal-dysplasia-using-combined-oct-and-angle-resolved-low-coherence-interferometry
#20
JOURNAL ARTICLE
Evan T Jelly, Zachary A Steelman, Haoran Zhang, Kengyeh K Chu, Cary C Cotton, Swathi Eluri, Nicholas J Shaheen, Adam Wax
Angle-resolved low-coherence interferometry (a/LCI) is an optical technique that enables depth-specific measurements of nuclear morphology, with applications to detecting epithelial cancers in various organs. Previous a/LCI setups have been limited by costly fiber-optic components and large footprints. Here, we present a novel a/LCI instrument incorporating a channel for optical coherence tomography (OCT) to provide real-time image guidance. We showcase the system's capabilities by acquiring imaging data from in vivo Barrett's esophagus patients...
March 1, 2024: Biomedical Optics Express
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