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Center of mass in knee osteoarthritis

Aarón Leonardo Pogacnik Murillo, Felix Eckstein, Wolfgang Wirth, Daniel Beavers, Richard F Loeser, Barbara J Nicklas, Shannon L Mihalko, Gary D Miller, David J Hunter, Stephen P Messier
OBJECTIVES: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. Here we examined the impact of weight loss by diet and/or exercise interventions on the IPFP volume. METHODS: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis...
2017: Cells, Tissues, Organs
Robert F LaPrade, Lauren M Matheny, Samuel G Moulton, Evan W James, Chase S Dean
BACKGROUND: Outcomes after transtibial pull-out repair for posterior meniscal root tears remain underreported, and factors that may affect outcomes are unknown. Purpose/Hypothesis: The purpose of this study was to compare patient-centered outcomes after transtibial pull-out repair for posterior root tears in patients <50 and ≥50 years of age. We hypothesized that improvement in function and activity level at minimum 2-year follow-up would be similar among patients <50 years of age compared with patients ≥50 years and among patients undergoing medial versus lateral root repairs...
March 2017: American Journal of Sports Medicine
Gavin Stormont, Daniel Stormont
The aim of this study was to analyze short-term metal failures in well-placed Signature-guided Regenerex (Zimmer Biomet, Warsaw, IN) tibial components in a limited patient series. A retrospective, consecutive, nonrandomized, unblinded study from a limited cohort of young active osteoarthritis patients was conducted. All cases received a Regenerex tibial component which we evaluated for metal failure. Patients met the then current indications from the Center for Medicare and Medicaid Services Guidelines for knee replacement...
November 28, 2016: Journal of Knee Surgery
Nicolas Reina, Etienne Cavaignac, Régis Pailhé, Aymeric Pailliser, Nicolas Bonnevialle, Pascal Swider, Jean-Michel Laffosse
Overweight is a risk factor for osteoarthritis on the knees. Subchondral trabecular bone (SCTB) densification has been shown to be associated with cartilage degeneration. This study analyzed the microarchitectural changes in the SCTB of tibial plateaus to validate the hypothesis that the degree of remodeling is correlated with a patient's body weight. Twenty-one tibial plateaus were collected during total knee arthroplasty from 21 patients (15 women and 6 men). These patients had a mean age of 70.4 years (49-81), mean weight of 74...
October 17, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Bashir Zikria, Nima Hafezi-Nejad, Frank W Roemer, Ali Guermazi, Shadpour Demehri
Purpose To investigate the risk of radiographic joint space narrowing (JSN) progression evaluated in subjects with and those without underlying osteoarthritis at baseline and knee replacement (KR) associated with meniscal surgery in subjects with and those without a reported history of preceding knee trauma. Materials and Methods The HIPAA-compliant protocol was approved by the institutional review boards of the participating centers. Written informed consent was obtained from all participants. Subjects who underwent meniscal surgery with a preceding knee trauma at baseline (n = 564) and those without (n = 147) were drawn from the Osteoarthritis Initiative cohort (n = 4796)...
March 2017: Radiology
S Vasilic-Brasnjevic, J Marinkovic, H Vlajinac, N Vasiljevic, B Jakovljevic, M Nikic, M Maksimovic
AIM: The aim of the present study was to investigate the association of the body mass index (BMI) and waist circumference (WC) with the severity of radiographic severity of knee osteoarthritis (rKOA) Methods. A cross-sectional study had been applied during the research which included 150 patients diagnosed at the General Hospital in Užice and Health Center in Arilje (Serbia). The study included patients over the age of 50 diagnosed with OA according to The European League Against Rheumatism (EULAR) criteria...
July 2016: Acta Reumatológica Portuguesa
Ki Deok Park, Woo Yong Lee, Jihae Lee, Min-Ho Park, Jae Ki Ahn, Yongbum Park
BACKGROUND: Trochanteric bursa injections of corticosteroids and local anesthetics have been shown to provide pain relief for the treatment of greater trochanteric pain syndrome (GTPS). However, symptom recurrence and incomplete symptom relief are common. The reason for the variation in response is unclear but may be related to disease-, treatment-, or patient-related factors. OBJECTIVE: To determine whether there are factors related to patient, treatment, or disease that can predict either the magnitude or duration of response to ultrasound-guided trochanteric bursa injections for GTPS...
May 2016: Pain Physician
Benedikt J Schwaiger, Alexandra S Gersing, John Mbapte Wamba, Michael C Nevitt, Charles E McCulloch, Thomas M Link
Purpose To determine the incidence with which morphologic articular cartilage defects develop over 48 months in cartilage with signal abnormalities at baseline magnetic resonance (MR) imaging in comparison with the incidence in articular cartilage without signal abnormalities at baseline. Materials and Methods The institutional review boards of all participating centers approved this HIPAA-compliant study. Right knees of 90 subjects from the Osteoarthritis Initiative (mean age, 55 years ± 8 [standard deviation]; 51% women) with cartilage signal abnormalities but without morphologic cartilage defects at 3...
October 2016: Radiology
Ryan T Lewinson, Darren J Stefanyshyn
Wedged insoles are prescribed for medial knee osteoarthritis to reduce the knee adduction moment; however, it is currently not possible to predict which patients will in fact experience reduced moments. The purpose of this study was to identify a simple method using two-dimensional data for predicting the expected change in knee adduction moments with wedged insoles. Knee adduction moments during walking were determined for healthy individuals (n = 15) and individuals with medial knee osteoarthritis (n = 19) while wearing their own shoe without an insole (control), with a 6-mm medial wedge and with a 6-mm lateral wedge...
April 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Hun-Tae Kim, Hyun-Je Kim, Hee-Yun Ahn, Young-Hoon Hong
BACKGROUND/AIMS: This study was conducted in order to analyze the effects of sarcopenia on age-related osteoarthritis (OA) of the knee in a Korean population. METHODS: All the Korean subjects who visited the Yeungnam University Medical Center Health Promotion Center between 2008 and 2012 in order to undergo a routine medical examination were enrolled. A total of 5,723 young, healthy people (2,959 males, 2,764 females) enrolled as normal subjects and 23,473 subjects (13,006 males and 10,467 females) were included for evaluation of the effects of sarcopenia on OA...
May 2016: Korean Journal of Internal Medicine
Michelle M Dowsey, Tim Spelman, Peter F M Choong
BACKGROUND: Indications for total knee arthroplasty (TKA) currently depend on clinical judgment. Up to one fifth of those who undergo primary TKA do not report a clinically meaningful improvement in pain and function after surgery. Our aim was to develop and internally validate a prognostic tool for predicting the probability of nonresponse to surgery at 12 months. METHODS: Patients from 1 center who underwent primary TKA (N = 615) between 2012 and 2013. The Western Ontario and McMaster Universities Arthritis Index was collected pre- and 12 months after TKA from which nonresponse to surgery was determined using the Outcome Measures in Rheumatology-Osteoarthritis Research Society International responder criteria...
August 2016: Journal of Arthroplasty
K Linnea Welton, Joel J Gagnier, Andrew G Urquhart
The purpose of this study is to demonstrate that the percentage of obese individuals initially presenting to total joint arthroplasty clinics in a public, tertiary hospital is greater than the proportion of obese individuals in the general population. In a retrospective, comparative study of patients seen in total joint replacement clinics at a public, tertiary hospital with an ICD-9 diagnosis of hip or knee osteoarthritis and documented body mass index, the proportion of obese individuals was compared with recent obesity data for the general population from the Centers for Disease Control and Prevention...
January 2016: Orthopedics
Yumiko Koyama, Hiroshige Tateuchi, Riho Nishimura, Xiang Ji, Hiroki Umegaki, Masashi Kobayashi, Noriaki Ichihashi
BACKGROUND: The ability to descend stairs independently is impaired from a relatively early stage in patients with knee osteoarthritis. The purpose of this study was to evaluate the performance in patients with knee osteoarthritis when stepping down a step by evaluating the dynamic stability using the extrapolated center of mass. METHODS: Twenty-three individuals with medial knee osteoarthritis were evaluated during step descent without any assistance. Kinematic/kinetic data were collected using a three-dimensional motion analysis system and force platforms...
December 2015: Clinical Biomechanics
Andrew J Kittelson, Jennifer E Stevens-Lapsley, Sarah J Schmiege
OBJECTIVE: Knee osteoarthritis (OA) is a broadly applied diagnosis that may describe multiple subtypes of pain. The purpose of this study was to identify phenotypes of knee OA, using measures from the following pain-related domains: 1) knee OA pathology, 2) psychological distress, and 3) altered pain neurophysiology. METHODS: Data were selected from a total of 3,494 participants at visit 6 of the Osteoarthritis Initiative study. Latent class analysis was applied to the following variables: radiographic OA severity, quadriceps strength, body mass index, the Charlson Comorbidity Index (CCI), the Center for Epidemiologic Studies Depression Scale, the Coping Strategies Questionnaire-Catastrophizing subscale, number of bodily pain sites, and knee joint tenderness at 4 sites...
May 2016: Arthritis Care & Research
Barak Haviv, Shlomo Bronak, Rafael Thein
BACKGROUND: Chondral lesions of the knee are commonly found during arthroscopic partial meniscectomy. The literature advises against arthroscopic medial meniscectomy in the presence of advanced chondral derangement because of unfavorable outcome. Recent studies have shown an association between obesity and chondropathy in patients with meniscal tears. The aim of this study was to assess whether body mass index (BMI) correlates with the severity of chondral lesions in patients with isolated medial meniscus tears (i...
March 2015: Indian Journal of Orthopaedics
Thomas Kampfrath, Penny Peng, Valli Vairavan, Dayong Lee
CLINICAL HISTORY: HASH(0x3a13a28) PATIENT: 41-year-old Hispanic woman. Chief Complaint: Pain in the neck, joints, and shoulders that started in August 2013. History of Present Illness: The patient has a history of psychiatric illness. Her primary care physician from an outside facility had prescribed alprazolam (Xanax) to treat her depression. The patient reported that in 2011 she experienced pain in the right side of her back and was diagnosed with sciatica. In addition, she was diagnosed with systemic lupus erythematosus (SLE) based on a positive finding for antinuclear antibodies (ANA) and double-stranded DNA (ds-DNA)...
2015: Laboratory Medicine
Sharon Bout-Tabaku, Marc P Michalsky, Todd M Jenkins, Amy Baughcum, Meg H Zeller, Mary L Brandt, Anita Courcoulas, Ralph Buncher, Michael Helmrath, Carroll M Harmon, Mike K Chen, Thomas H Inge
IMPORTANCE: Obesity is associated with chronic musculoskeletal pain and is a risk factor for disability and osteoarthritis. OBJECTIVES: To describe the prevalence, sites, and intensity of musculoskeletal pain in adolescents with severe obesity; to evaluate associations between musculoskeletal pain and self-reported physical function as well as weight-related quality of life; and to evaluate the association between musculoskeletal pain and high-sensitivity C-reactive protein level...
June 2015: JAMA Pediatrics
R Papalia, G Di Pino, A Tecame, G Vadalà, D Formica, A Di Martino, E Albo, V Di Lazzaro, V Denaro
The aim of this review is to collect and discuss the current best evidence published in literature about the effect of the Masai Barefoot Technology(MBT) shoes on gait and muscle activation and try to draw conclusions on the possible benefits. We searched Medline, CINAHL, Embase and the Cochrane Central Registry of Controlled Trials. The reference lists of the previously selected articles were then examined by hand. Only studies comparing biomechanical and clinical outcomes were selected. Review, anatomical studies, letter to editor and instructional course were excluded...
December 2015: Musculoskeletal Surgery
Camille J Shanahan, Tim V Wrigley, Michael J Farrell, Kim L Bennell, Paul W Hodges
The mechanisms for proprioceptive changes associated with knee osteoarthritis (OA) remain elusive. Observations of proprioceptive changes in both affected knees and other joints imply more generalized mechanisms for proprioceptive impairment. However, evidence for a generalized effect remains controversial. This study examined whether joint repositioning proprioceptive deficits are localized to the diseased joint (knee) or generalized across other joints (elbow and ankle) in people with knee OA. Thirty individuals with right knee OA (17 female, 66±7 [mean±SD] years) of moderate/severe radiographic disease severity and 30 healthy asymptomatic controls of comparable age (17 female, 65±8years) performed active joint repositioning tests of the knee, ankle and elbow in randomised order in supine...
June 2015: Human Movement Science
Yi-Jen Chen, Chia-Hsin Chen, Chao-Ling Wang, Mao-Hsiung Huang, Tien-Wen Chen, Chia-Ling Lee
OBJECTIVE: To determine the association between the severity of femoral condylar cartilage erosion resulting from knee osteoarthritis (OA) by an ultrasonographic grading system and the clinical symptoms and functions. DESIGN: Cross-sectional study. SETTING: A tertiary center. PARTICIPANTS: Participants (N=101) with and without subjective complaints of knee discomfort were consecutively enrolled. Patients who had ever received knee arthroplasty, who had inflammatory arthritis, and whose knee flexion range of motion was <90° were excluded...
May 2015: Archives of Physical Medicine and Rehabilitation
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