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Center of mass in knee osteoarthritis

Christopher R Abrecht, Marise Cornelius, Albert Wu, Robert N Jamison, David Janfaza, Richard D Urman, Claudia Campbell, Michael Smith, Jennifer Haythornthwaite, Robert R Edwards, Kristin L Schreiber
Objective: To identify factors associated with pain severity and opioid consumption in the early perioperative period. Design: Prospective observational cohort study. Setting: Tertiary academic medical center. Subjects: Patients with osteoarthritis older than age 45 years undergoing primary total knee replacement at Brigham and Women's Hospital. A total of 126 patients enrolled. Methods: Preoperatively, pain questionnaires and quantitative sensory testing were performed on patients to develop a psychosocial and psychophysical profile...
March 7, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Yun-A Shin, Min-Hwa Suk, Hee-Seung Jang, Hye-Jung Choi
The purpose of this study was to investigate the short-term of Theracurmin dose and exercise type on pain, walking ability, and muscle function in patients with knee osteoarthritis. Twenty-five patients with knee osteoarthritis randomly selected to Theracurmin intake (T) group and Theracurmin in combined with exercise (T+E) group. T group (n= 13) was taken orally a capsule of 700 mg, 3 times per day, (total 2,100 mg, 35 mg/kg-body weight). T+E group (n= 12) performed aerobic training of 30-min walking and weight training for increasing leg muscular strength...
December 2017: Journal of Exercise Rehabilitation
Sudhakar Tummala, Dieuwke Schiphof, Inger Byrjalsen, Erik B Dam
Objective Gender is a risk factor in the onset of osteoarthritis (OA). The aim of the study was to investigate gender differences in contact area (CA) and congruity index (CI) in the medial tibiofemoral (MTF) joint in 2 different cohorts, quantified automatically from magnetic resonance imaging (MRI). Design The CA and CI markers were validated on 2 different data sets from Center for Clinical and Basic Research (CCBR) and Osteoarthritis Initiative (OAI). The CCBR cohort consisted of 159 subjects and the OAI subcohort consisted of 1,436 subjects...
January 2018: Cartilage
Saad M Bindawas, Vishal Vennu, Brendon Stubbs
Objective: Examine the longitudinal association between knee pain and prefrailty/frailty. Design: Longitudinal study. Setting: Five clinical centers across the United States. Subjects: Data from 3,053 nonfrail participants aged 45-79 years at baseline from the Osteoarthritis Initiative. Methods: According to self-reported knee pain at baseline, the participants were placed into three groups: no knee pain (N = 1,600), unilateral knee pain (N = 822), and bilateral knee pain (N = 631)...
December 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Kazuki Tokuda, Masaya Anan, Makoto Takahashi, Tomonori Sawada, Kenji Tanimoto, Nobuhiro Kito, Koichi Shinkoda
The biomechanical mechanism of lateral trunk lean gait employed to reduce external knee adduction moment (KAM) for knee osteoarthritis (OA) patients is not well known. This mechanism may relate to the center of mass (COM) motion. Moreover, lateral trunk lean gait may affect motor control of the COM displacement. Uncontrolled manifold (UCM) analysis is an evaluation index used to understand motor control and variability of the motor task. Here we aimed to clarify the biomechanical mechanism to reduce KAM during lateral trunk lean gait and how motor variability controls the COM displacement...
November 4, 2017: Journal of Biomechanics
Chao Zeng, Jie Wei, Robert Terkeltaub, Tuo Yang, Hyon K Choi, Yi-Lun Wang, Dong-Xing Xie, David J Hunter, Yuqing Zhang, Hui Li, Yang Cui, Liang-Jun Li, Guang-Hua Lei
BACKGROUND: The aim was to assess serum magnesium levels in relation to prevalence of knee chondrocalcinosis in two population-based Chinese studies. METHODS: Data included in this analysis consisted of two population-based cross-sectional studies, i.e., the Xiangya Hospital Health Management Center Study and the Xiangya Osteoarthritis (XO) Study I. A bilateral knee anteroposterior radiograph was obtained from each subject. Radiographic knee chondrocalcinosis was present if there was definite linear cartilage calcification...
October 24, 2017: Arthritis Research & Therapy
Yosuke Yoshida, Koki Ikuno, Koji Shomoto
OBJECTIVE: To compare sensory-level neuromuscular electrical stimulation (NMES) and conventional motor-level NMES in patients after total knee arthroplasty. DESIGN: Prospective randomized single-blind trial. SETTING: Hospital total arthroplasty center: inpatients. PARTICIPANTS: Patients with osteoarthritis (N=66; mean age, 73.5±6.3y; 85% women) were randomized to receive either sensory-level NMES applied to the quadriceps (the sensory-level NMES group), motor-level NMES (the motor-level NMES group), or no stimulation (the control group) in addition to a standard rehabilitation program...
December 2017: Archives of Physical Medicine and Rehabilitation
Alexandra S Gersing, Benedikt J Schwaiger, Michael C Nevitt, Gabby B Joseph, Nattagan Chanchek, Julio B Guimaraes, John Mbapte Wamba, Luca Facchetti, Charles E McCulloch, Thomas M Link
Purpose To investigate the association of weight loss with progression of cartilage changes at magnetic resonance (MR) imaging over 48 months in overweight and obese participants compared with participants of stable weight. Materials and Methods The institutional review boards of the four participating centers approved this HIPAA-compliant study. Included were (a) 640 participants (mean age, 62.9 years ± 9.1 [standard deviation]; 398 women) who were overweight or obese (body mass index cutpoints of 25 and 30 kg/m2, respectively) from the Osteoarthritis Initiative, with risk factors for osteoarthritis or mild to moderate radiographic findings of osteoarthritis, categorized into groups with (a) weight loss of more than 10% (n = 82), (b) weight loss of 5%-10% (n = 238), or (c) stable weight (n = 320) over 48 months...
August 2017: Radiology
Aarón Leonardo Pogacnik Murillo, Felix Eckstein, Wolfgang Wirth, Daniel Beavers, Richard F Loeser, Barbara J Nicklas, Shannon L Mihalko, Gary D Miller, David J Hunter, Stephen P Messier
OBJECTIVES: The infrapatellar fat pad (IPFP) represents intra-articular adipose tissue that may contribute to intra-articular inflammation and pain by secretion of proinflammatory cytokines. Here we examined the impact of weight loss by diet and/or exercise interventions on the IPFP volume. METHODS: Intensive Diet and Exercise for Arthritis (IDEA) was a single-blinded, single-center, 18-month, prospective, randomized controlled trial that enrolled 454 overweight and obese older adults with knee pain and radiographic osteoarthritis...
2017: Cells, Tissues, Organs
Robert F LaPrade, Lauren M Matheny, Samuel G Moulton, Evan W James, Chase S Dean
BACKGROUND: Outcomes after transtibial pull-out repair for posterior meniscal root tears remain underreported, and factors that may affect outcomes are unknown. Purpose/Hypothesis: The purpose of this study was to compare patient-centered outcomes after transtibial pull-out repair for posterior root tears in patients <50 and ≥50 years of age. We hypothesized that improvement in function and activity level at minimum 2-year follow-up would be similar among patients <50 years of age compared with patients ≥50 years and among patients undergoing medial versus lateral root repairs...
March 2017: American Journal of Sports Medicine
Gavin Stormont, Daniel Stormont
The aim of this study was to analyze short-term metal failures in well-placed Signature-guided Regenerex (Zimmer Biomet, Warsaw, IN) tibial components in a limited patient series. A retrospective, consecutive, nonrandomized, unblinded study from a limited cohort of young active osteoarthritis patients was conducted. All cases received a Regenerex tibial component which we evaluated for metal failure. Patients met the then current indications from the Center for Medicare and Medicaid Services Guidelines for knee replacement...
July 2017: Journal of Knee Surgery
Nicolas Reina, Etienne Cavaignac, Régis Pailhé, Aymeric Pailliser, Nicolas Bonnevialle, Pascal Swider, Jean-Michel Laffosse
Overweight is a risk factor for osteoarthritis on the knees. Subchondral trabecular bone (SCTB) densification has been shown to be associated with cartilage degeneration. This study analyzed the microarchitectural changes in the SCTB of tibial plateaus to validate the hypothesis that the degree of remodeling is correlated with a patient's body weight. Twenty-one tibial plateaus were collected during total knee arthroplasty from 21 patients (15 women and 6 men). These patients had a mean age of 70.4 years (49-81), mean weight of 74...
August 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Bashir Zikria, Nima Hafezi-Nejad, Frank W Roemer, Ali Guermazi, Shadpour Demehri
Purpose To investigate the risk of radiographic joint space narrowing (JSN) progression evaluated in subjects with and those without underlying osteoarthritis at baseline and knee replacement (KR) associated with meniscal surgery in subjects with and those without a reported history of preceding knee trauma. Materials and Methods The HIPAA-compliant protocol was approved by the institutional review boards of the participating centers. Written informed consent was obtained from all participants. Subjects who underwent meniscal surgery with a preceding knee trauma at baseline (n = 564) and those without (n = 147) were drawn from the Osteoarthritis Initiative cohort (n = 4796)...
March 2017: Radiology
S Vasilic-Brasnjevic, J Marinkovic, H Vlajinac, N Vasiljevic, B Jakovljevic, M Nikic, M Maksimovic
AIM: The aim of the present study was to investigate the association of the body mass index (BMI) and waist circumference (WC) with the severity of radiographic severity of knee osteoarthritis (rKOA) Methods. A cross-sectional study had been applied during the research which included 150 patients diagnosed at the General Hospital in Užice and Health Center in Arilje (Serbia). The study included patients over the age of 50 diagnosed with OA according to The European League Against Rheumatism (EULAR) criteria...
July 2016: Acta Reumatológica Portuguesa
Ki Deok Park, Woo Yong Lee, Jihae Lee, Min-Ho Park, Jae Ki Ahn, Yongbum Park
BACKGROUND: Trochanteric bursa injections of corticosteroids and local anesthetics have been shown to provide pain relief for the treatment of greater trochanteric pain syndrome (GTPS). However, symptom recurrence and incomplete symptom relief are common. The reason for the variation in response is unclear but may be related to disease-, treatment-, or patient-related factors. OBJECTIVE: To determine whether there are factors related to patient, treatment, or disease that can predict either the magnitude or duration of response to ultrasound-guided trochanteric bursa injections for GTPS...
May 2016: Pain Physician
Benedikt J Schwaiger, Alexandra S Gersing, John Mbapte Wamba, Michael C Nevitt, Charles E McCulloch, Thomas M Link
Purpose To determine the incidence with which morphologic articular cartilage defects develop over 48 months in cartilage with signal abnormalities at baseline magnetic resonance (MR) imaging in comparison with the incidence in articular cartilage without signal abnormalities at baseline. Materials and Methods The institutional review boards of all participating centers approved this HIPAA-compliant study. Right knees of 90 subjects from the Osteoarthritis Initiative (mean age, 55 years ± 8 [standard deviation]; 51% women) with cartilage signal abnormalities but without morphologic cartilage defects at 3...
October 2016: Radiology
Ryan T Lewinson, Darren J Stefanyshyn
Wedged insoles are prescribed for medial knee osteoarthritis to reduce the knee adduction moment; however, it is currently not possible to predict which patients will in fact experience reduced moments. The purpose of this study was to identify a simple method using two-dimensional data for predicting the expected change in knee adduction moments with wedged insoles. Knee adduction moments during walking were determined for healthy individuals (n = 15) and individuals with medial knee osteoarthritis (n = 19) while wearing their own shoe without an insole (control), with a 6-mm medial wedge and with a 6-mm lateral wedge...
April 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Hun-Tae Kim, Hyun-Je Kim, Hee-Yun Ahn, Young-Hoon Hong
BACKGROUND/AIMS: This study was conducted in order to analyze the effects of sarcopenia on age-related osteoarthritis (OA) of the knee in a Korean population. METHODS: All the Korean subjects who visited the Yeungnam University Medical Center Health Promotion Center between 2008 and 2012 in order to undergo a routine medical examination were enrolled. A total of 5,723 young, healthy people (2,959 males, 2,764 females) enrolled as normal subjects and 23,473 subjects (13,006 males and 10,467 females) were included for evaluation of the effects of sarcopenia on OA...
May 2016: Korean Journal of Internal Medicine
Michelle M Dowsey, Tim Spelman, Peter F M Choong
BACKGROUND: Indications for total knee arthroplasty (TKA) currently depend on clinical judgment. Up to one fifth of those who undergo primary TKA do not report a clinically meaningful improvement in pain and function after surgery. Our aim was to develop and internally validate a prognostic tool for predicting the probability of nonresponse to surgery at 12 months. METHODS: Patients from 1 center who underwent primary TKA (N = 615) between 2012 and 2013. The Western Ontario and McMaster Universities Arthritis Index was collected pre- and 12 months after TKA from which nonresponse to surgery was determined using the Outcome Measures in Rheumatology-Osteoarthritis Research Society International responder criteria...
August 2016: Journal of Arthroplasty
K Linnea Welton, Joel J Gagnier, Andrew G Urquhart
The purpose of this study is to demonstrate that the percentage of obese individuals initially presenting to total joint arthroplasty clinics in a public, tertiary hospital is greater than the proportion of obese individuals in the general population. In a retrospective, comparative study of patients seen in total joint replacement clinics at a public, tertiary hospital with an ICD-9 diagnosis of hip or knee osteoarthritis and documented body mass index, the proportion of obese individuals was compared with recent obesity data for the general population from the Centers for Disease Control and Prevention...
January 2016: Orthopedics
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