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https://www.readbyqxmd.com/read/29146643/are-il18rap-gene-polymorphisms-associated-with-body-mass-regulation-a-cross-sectional-study
#1
Vanesa Martínez-Barquero, Griselda de Marco, Sergio Martínez-Hervas, Victoria Adam-Felici, Cristina Pérez-Soriano, Verónica Gonzalez-Albert, Gemma Rojo, Juan Francisco Ascaso, José Tomás Real, Ana Barbara Garcia-Garcia, Juan Carlos Martín-Escudero, Raquel Cortes, Felipe Javier Chaves
OBJECTIVES: To investigate the association between IL18RAP and body mass index (BMI) and obesity and to verify the effect of a polymorphism in the microRNA136 (MIR136) IL18RAP binding region. DESIGN: We analysed samples from two Spanish cross-sectional studies, VALCAR (Spanish Mediterranean coast) and Hortega (Spanish centre). These studies aimed at analysing cardiovascular risk and development of cardiovascular disease in the general population. Both populations correspond to regions with different characteristics...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29143443/multiscale-characterisation-of-cortical-bone-composition-microstructure-and-nanomechanical-properties-in-experimentally-induced-osteoporosis
#2
Furqan A Shah, Adrian Stoica, Carina Cardemil, Anders Palmquist
Cortical bone plays a vital role in determining overall bone strength. We investigate the structural, compositional, and nanomechanical properties of cortical bone following ovariectomy (OVX) of 12 week old Sprague Dawley rats, since this animal model is frequently employed to evaluate the performance of implantable biomaterials in compromised bone healing conditions. Morphological parameters and material properties of bone in the geometrical centre of the femoral cortex were investigated four and eight weeks post-OVX and in unoperated controls (Ctrl), using X-ray micro-computed tomography, backscattered electron scanning electron microscopy, Raman spectroscopy, and nanoindentation...
November 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29138173/cardiovascular-preventive-care-for-patients-with-serious-mental-illness
#3
Sarah Ritchie, Laura Muldoon
OBJECTIVE: To determine whether patients with serious mental illness (SMI) are receiving preventive care for cardiovascular disease at the same rate as those without SMI in an interprofessional practice with a mandate to care for persons with barriers to access to the health care system. DESIGN: Quality improvement exercise using a case-matched retrospective chart review. SETTING: Somerset West Community Health Centre in downtown Ottawa, Ont...
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29135910/sleep-disordered-breathing-in-children-with-recurrent-wheeze-asthma-a-single-centre-study
#4
Marco Zaffanello, Emma Gasperi, Laura Tenero, Michele Piazza, Angelo Pietrobelli, Luca Sacchetto, Franco Antoniazzi, Giorgio Piacentini
The relationship between asthma and sleep-disordered breathing is bidirectional due to common risk factors that promote airway inflammation. Obstructive sleep-disordered breathing and recurrent wheeze/asthma are conditions that involve the upper and the lower respiratory system, respectively. The aim of the present study was to investigate the sleep disordered breathing in children with recurrent wheeze/asthma. This was a retrospective study concerning children older than 2 years who underwent-between January 2014 and November 2016-an in-laboratory overnight polygraphic study...
November 14, 2017: Children
https://www.readbyqxmd.com/read/29133383/structured-education-programme-for-women-with-polycystic-ovary-syndrome-a-randomised-controlled-trial
#5
Hamidreza Mani, Yogini Chudasama, Michelle Hadjiconstantinou, Daniel H Bodicoat, Charlotte Edwardson, Miles Levy, Laura J Gray, Janette Barnett, Heather Daly, Trevor A Howlett, Kamlesh Khunti, Melanie J Davies
OBJECTIVE: To evaluate the effectiveness of a structured education programmes in women with polycystic ovary syndrome (PCOS). METHODS: Single centre, randomised controlled trial, testing a single exposure to a group-based, face-to-face, structured education programme. Inclusion criteria were women with PCOS, aged 18-49 years inclusive and Body Mass Index ≥ 23 kg/m2 for Black and Minority Ethnicities or ≥ 25 kg/m2 for White Europeans. Primary outcome was step count/day at 12 months...
November 13, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29128183/does-intraoperative-neuromonitoring-of-recurrent-nerves-have-an-impact-on-the-postoperative-palsy-rate-results-of-a-prospective-multicenter-study
#6
Éric Mirallié, Cécile Caillard, François Pattou, Laurent Brunaud, Antoine Hamy, Marcel Dahan, Michel Prades, Muriel Mathonnet, Gérard Landecy, Henri-Pierre Dernis, Jean-Christophe Lifante, Frederic Sebag, Franck Jegoux, Emmanuel Babin, Alain Bizon, Florent Espitalier, Isabelle Durand-Zaleski, Christelle Volteau, Claire Blanchard
BACKGROUND: The impact of intraoperative neuromonitoring on recurrent laryngeal nerve palsy remains debated. Our aim was to evaluate the potential protective effect of intraoperative neuromonitoring on recurrent laryngeal nerve during total thyroidectomy. METHODS: This was a prospective, multicenter French national study. The use of intraoperative neuromonitoring was left at the surgeons' choice. Postoperative laryngoscopy was performed systematically at day 1 to 2 after operation and at 6 months in case of postoperative recurrent laryngeal nerve palsy...
November 8, 2017: Surgery
https://www.readbyqxmd.com/read/29127228/association-between-body-mass-index-and-outcomes-after-percutaneous-coronary-intervention-in-multiethnic-south-east-asian-population-a-retrospective-analysis-of-the-malaysian-national-cardiovascular-disease-database-percutaneous-coronary-intervention-ncvd-pci
#7
Zaid Azhari, Muhammad Dzafir Ismail, Ahmad Syadi Mahmood Zuhdi, Norashikin Md Sari, Imran Zainal Abidin, Wan Azman Wan Ahmad
OBJECTIVE: To examine the relationship between body mass index (BMI) and outcomes after percutaneous coronary intervention (PCI) in a multiethnic South East Asian population. SETTING: Fifteen participating cardiology centres contributed to the Malaysian National Cardiovascular Disease Database-Percutaneous Coronary Intervention (NCVD-PCI) registry. PARTICIPANTS: 28 742 patients from the NCVD-PCI registry who had their first PCI between January 2007 and December 2014 were included...
November 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/29125990/structural-characterization-of-the-new-synthetic-cannabinoids-cumyl-pinaca-5f-cumyl-pinaca-cumyl-4cn-binaca-5f-cumyl-p7aica-and-cumyl-4cn-b7aica
#8
Michael Bovens, Christian Bissig, Sandra N Staeheli, Michael Poetzsch, Bernhard Pfeiffer, Thomas Kraemer
Synthetic cannabinoids are a group of new psychoactive compounds (NPS) that act as agonists at the cannabinoid receptor. First reported in 2008, they currently represent one of the largest groups of NPS that are monitored by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Five samples (4 from the European RESPONSE project and one from daily casework) containing different synthetic cannabinoids were analyzed by a complex of analytical methods including gas chromatography-electron ionization mass spectrometry (GC-EI-MS), liquid chromatography-high resolution mass spectrometry (LC-HRMS), infrared spectroscopy (IR) and nuclear magnetic resonance spectroscopy (NMR)...
October 18, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29125985/cadmium-toxicity-and-its-amelioration-by-kinetin-in-tomato-seedlings-vis-%C3%A3-vis-ascorbate-glutathione-cycle
#9
Shikha Singh, Anita Singh, Prabhat Kumar Srivastava, Sheo Mohan Prasad
The supplementation of plant hormones may enhance the tolerance capacity of plants against certain environmental stresses by increasing their physiological functioning and detoxification capacity. To answer the question that whether a phytohormone 'kinetin' (KN, 6-furfuylaminopurine), one of the artificial cytokinins could ameliorate the cadmium induced toxicity in tomato seedlings, the effect of KN was assessed in differentially cadmium (Cd1: 3mgkg(-1) sand and Cd2: 9mgkg(-1) sand) intoxicated tomato seedlings by estimating the changes in reactive oxygen species (ROS, viz...
October 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29123584/analysis-of-postoperative-morbidity-and-mortality-following-surgery-for-gastric-cancer-surgeon-volume-as-the-most-significant-prognostic-factor
#10
Maciej Ciesielski, Wiesław J Kruszewski, Jakub Walczak, Mariusz Szajewski, Jarosław Szefel, Jacek Wydra, Tomasz Buczek, Maksymilian Czerepko
Introduction: Surgical resection is the only potentially curative modality for gastric cancer and it is associated with substantial morbidity and mortality. Aim: To determine risk factors for postoperative morbidity and mortality following major surgery for gastric cancer. Material and methods: Between 1.08.2006 and 30.11.2014 in the Department of Oncological Surgery of Gdynia Oncology Centre 162 patients underwent gastric resection for adenocarcinoma...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29120123/the-value-of-multidetector-computed-tomography-of-orbits-in-globe-protrusion-in-comparison-to-hertel-exophthalmometry
#11
Igor Đorić, Miloš Žarković, Zoran Radojičić, Nikola Repac, Aleksandar Janićijević, Krešimir Rotim, Goran Tasić, Lukas Rasulić
The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. The aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel exophthalmometry. A cross-sectional study was conducted at the Clinical Centre of Serbia and included 91 patients (19 male and 72 female) with verified Graves‘ orbitopathy. Globe protrusion measured by MDCT (globe protrusion, GPR) was correlated to Hertel measured protrusion (HR)...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29119069/targeting-the-tumor-assessing-the-impact-of-bladder-volume-and-position-on-accuracy-of-radiation-delivery-for-patients-with-bladder-cancer
#12
Andrew Kochan, Ryan Rivest, Katie Galloway, Pascal Lambert, Aldrich Ong, Rashmi Koul, Shahida Ahmed, Bashir Bashir, Harvey Quon
Context Daily variations in bladder size and position can negatively impact the ability to accurately deliver radiation. Aims We attempted to quantify how bladder volumes and positions change over the course of radiotherapy for muscle invasive bladder cancer and the planning target volume (PTV) margins required to account for such changes. Methods and material Cone-beam computed tomography (CT) images of 28 patients during their first, second, and third fractions and weekly thereafter were acquired. Bladders were contoured and the volume, centre of mass, and the maximal positions were recorded and compared to the planning CT scan...
September 1, 2017: Curēus
https://www.readbyqxmd.com/read/29114413/perioperative-factors-affecting-ambulatory-outcomes-following-laparoscopic-adjustable-gastric-banding
#13
Mirsad Dupanovic, Ron Krebill, Iris Dupanovic, John Nachtigal, Melissa Rockford, Walter Orr
Objective: Morbidly obese patients are traditionally hospitalised following bariatric surgery. However, laparoscopic-adjustable gastric banding (LAGB) is amenable for ambulatory care. We hypothesised that the majority of patients can receive an ambulatory LAGB and that both surgical and anaesthetic perioperative factors will significantly affect non-ambulatory LAGB outcomes. Methods: Medical records of 201 consecutive LAGB patients performed at the University of Kansas Medical Centre during a 3-y period were reviewed...
October 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29105045/modifying-attitude-and-intention-toward-regular-physical-activity-using-protection-motivation-theory-a-randomized-controlled-trial
#14
Kamal Mirkarimi, Maryam Eri, Mohammad R Ghanbari, Mohammad J Kabir, Mojtaba Raeisi, Rahman B Ozouni-Davaji, Mohammad Aryaie, Abdurrahman Charkazi
We were guided by the Protection Motivation Theory to test the motivational interviewing effects on attitude and intention of obese and overweight women to do regular physical activity. In a randomized controlled trial, we selected using convenience sampling 60 overweight and obese women attending health centres. The women were allocated to 2 groups of 30 receiving a standard weight-control programme or motivational interviewing. All constructs of the theory (perceived susceptibility, severity, self-efficacy and response efficacy) and all anthropometric characteristics (except body mass index) were significantly different between the groups at 3 study times...
October 30, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29100924/a-practical-method-to-calculate-the-r1-index-of-waste-to-energy-facilities
#15
Federico Viganò
According to Directive 98/2008/EC, the operation carried out by an incinerator of Municipal Solid Waste (MSW) is classified either as energy recovery (R1) or as disposal (D10) depending on the result achieved by the application of the R1 formula. In 2011 the DG Environment of the European Commission (EC) issued some non-binding guidelines on the interpretation of such a formula that clarified many aspects related to its application. A point not fully clarified by the EC guidelines is the determination of the energy contained in the treated waste (EW)...
October 31, 2017: Waste Management
https://www.readbyqxmd.com/read/29094998/-nutritional-and-functional-state-of-patients-with-chronic-obstructive-pulmonary-disease-effects-of-oral-nutritional-supplementation-ofos-study
#16
Maria Del Pilar Benito Martínez, Jorge Estanislao La Serna Infantes, Marta Guarro Riba, Mireia Morera Inglès, Diego Marco Camere Colarossi, Marco Antonio Camere Torrealva
INTRODUCTION: Weight loss and malnutrition are associated with a worse prognosis of chronic obstructive pulmonary disease (COPD). OBJECTIVE: The main objective of the OFOS study was to assess the efficacy and tolerability of a new nutritional oral formula in adults with COPD with weight loss or malnutrition. METHODS: Prospective, single-centre, randomized, open-label and controlled trial conducted in Lima (Peru). A total of 99 outpatients of both sexes were included (control [GC]: 49; supplement [GS]: 50), aged from 18 to 80 years old, who had been diagnosed with COPD and that suffered from malnutrition or involuntary weight loss during the last months...
July 28, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29094694/spectroscopic-identification-of-r-process-nucleosynthesis-in-a-double-neutron-star-merger
#17
E Pian, P D'Avanzo, S Benetti, M Branchesi, E Brocato, S Campana, E Cappellaro, S Covino, V D'Elia, J P U Fynbo, F Getman, G Ghirlanda, G Ghisellini, A Grado, G Greco, J Hjorth, C Kouveliotou, A Levan, L Limatola, D Malesani, P A Mazzali, A Melandri, P Møller, L Nicastro, E Palazzi, S Piranomonte, A Rossi, O S Salafia, J Selsing, G Stratta, M Tanaka, N R Tanvir, L Tomasella, D Watson, S Yang, L Amati, L A Antonelli, S Ascenzi, M G Bernardini, M Boër, F Bufano, A Bulgarelli, M Capaccioli, P Casella, A J Castro-Tirado, E Chassande-Mottin, R Ciolfi, C M Copperwheat, M Dadina, G De Cesare, A Di Paola, Y Z Fan, B Gendre, G Giuffrida, A Giunta, L K Hunt, G L Israel, Z-P Jin, M M Kasliwal, S Klose, M Lisi, F Longo, E Maiorano, M Mapelli, N Masetti, L Nava, B Patricelli, D Perley, A Pescalli, T Piran, A Possenti, L Pulone, M Razzano, R Salvaterra, P Schipani, M Spera, A Stamerra, L Stella, G Tagliaferri, V Testa, E Troja, M Turatto, S D Vergani, D Vergani
The merger of two neutron stars is predicted to give rise to three major detectable phenomena: a short burst of γ-rays, a gravitational-wave signal, and a transient optical-near-infrared source powered by the synthesis of large amounts of very heavy elements via rapid neutron capture (the r-process). Such transients, named 'macronovae' or 'kilonovae', are believed to be centres of production of rare elements such as gold and platinum. The most compelling evidence so far for a kilonova was a very faint near-infrared rebrightening in the afterglow of a short γ-ray burst at redshift z = 0...
November 2, 2017: Nature
https://www.readbyqxmd.com/read/29094063/a-single-centre-experience-of-day-case-laparoscopic-cholecystectomy-outcomes-by-body-mass-index-group
#18
Kirk Bowling, Samantha Leong, Sarah El-Badawy, Erfan Massri, Jaideep Rait, Jay Atkinson, Gandrapu Srinivas, Stuart Andrews
Aim: The purpose of this study was to evaluate whether patients with a high BMI can undergo safe day case LC for cholecystitis compared to groups of patients with a lower BMI. Setting: NHS District General Hospital, UK. Methods: A retrospective review of 2391 patients who underwent an attempted day case LC between 1 January 2009 and 15 August 2015 was performed. Patients were divided into five groups depending on their BMI. Inclusion criteria were patients undergoing elective day case laparoscopic cholecystectomy with cholecystitis on histology...
2017: Surgery Research and Practice
https://www.readbyqxmd.com/read/29084397/cardiac-remodelling-in-patients-undergoing-in-centre-nocturnal-haemodialysis-results-from-the-midnight-study-a-non-randomized-controlled-trial
#19
Matthew P M Graham-Brown, Darren R Churchward, Katherine L Hull, Rob Preston, Warren P Pickering, Helen C Eborall, Gerry P McCann, James O Burton
Evidence suggests extended-hours haemodialysis (HD) may improve cardiovascular, medical and quality-of-life outcomes. In-centre nocturnal haemodialysis (INHD) is an established but underutilized method of providing extended-hours treatment. This 6-month, non-randomized controlled trial (ISRCTN16672784) recruited 13 INHD patients and 12 control patients on conventional HD. The effects of treatment on left ventricular (LV) structure, function and myocardial fibrosis were assessed using cardiac magnetic resonance imaging and native T1 mapping...
October 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/29082051/primary-cutaneous-follicle-centre-lymphoma-with-hodgkin-and-reed-sternberg-like-cells-a-case-report-and-review-of-the-literature
#20
Fatima A Aldarweesh, Diana O Treaba
An elderly woman with a complex medical history presented with a left forearm mass that slowly developed for several months. The excisional biopsy of this skin mass was remarkable for involvement by a follicle centre cell derived lymphoma with a nodular and diffuse pattern associated with a subset of scattered Hodgkin and Reed-Sternberg like cells. Fluorescence in situ hybridization studies did not detect the presence of IgH-bcl2 fusion transcript, and molecular studies were negative for immunoglobulin heavy chain gene rearrangements and EBV DNA sequences...
2017: Case Reports in Hematology
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