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Atrial fibrilation

Vandenberk Bert, Vandael Eline, Robyns Tomas, Vandenberghe Joris, Garweg Christophe, Foulon Veerle, Ector Joris, Willems Rik
BACKGROUND: Incorporation of QTc in clinical decision support systems requires accurate QT-interval correction, also during common ECG abnormalities as ventricular conduction defects (VCD). We compared the performance and predictive value of QT correction formulas to design a patient-specific QT correction algorithm (QTcA). METHODS: The first ECG in adult patients with sinus rhythm (SR), atrial fibrillation (AF) and ventricular pacing (VP) was collected retrospectively...
June 21, 2018: Pacing and Clinical Electrophysiology: PACE
Shafaq Jawed, Ujala Zubair, Zarafshan Zubair
Mitral valve regurgitation (MVR) is the reverse passage of blood through the mitral valve when the valve fails to close during ventricle contraction. Transcatheter mitral valve repair and replacement (TMVR) is a recent technology that can benefit MVR patients as an alternative, minimally invasive, and safer solution than conventional open-heart surgical approaches. TMVR uses a catheter guided by ultrasonography to replace or repair the defective valve and has provided better clinical outcomes, decreased hospital stay, and reduced mortality rates...
April 18, 2018: Curēus
Paul Guedeney, Birgit Vogel, Roxana Mehran
Despite dual antiplatelet therapy (DAPT) including potent P2Y12 inhibitors, recurrent ischaemic events occur in a significant number of patients after acute coronary syndrome (ACS), warranting new antithrombotic strategies. Combinations of non-vitamin K antagonist oral anticoagulant (NOAC) with antiplatelet therapy have been tested in several large phases II and III randomised trials. Overall, current evidence suggests that the use of NOACs on top of DAPT after ACS reduces the rate of recurrent ischaemic events, albeit at the price of increased risk for major bleeding...
May 2018: Interventional Cardiology
Maurizio Lunati, Giuseppe Arena, Saverio Iacopino, Roberto Verlato, Claudio Tondo, Antonio Curnis, Stefano Porcellini, Luigi Sciarra, Giulio Molon, Gaetano Senatore, Loira Leoni, Giovanni Battista Perego, Werner Rauhe, Patrizia Pepi, Maurizio Landolina
AIMS: Cryoablation is an indicated therapy for the treatment of recurrent atrial fibrillation through pulmonary vein isolation; however, the optimal time between first diagnosis of atrial fibrillation and cryoablation is still unknown. We aimed to assess the clinical efficacy and safety of early versus later treatment of patients with paroxysmal atrial fibrillation by cryoablation. METHODS: Five hundred and ten patients underwent atrial fibrillation cryoablation and were prospectively followed for at least 6 months in 43 Italian cardiology centers...
June 20, 2018: Journal of Cardiovascular Medicine
Yun Gi Kim, Jaemin Shim, Dong-Hyeok Kim, Jong-Il Choi, Sang-Weon Park, Hui-Nam Pak, Young-Hoon Kim
INTRODUCTION: Radiofrequency catheter ablation (RFCA) in atrial fibrillation (AF) patients can cause various complications and atrioesophageal (AE) fistula is one of the most catastrophic complications of RFCA. METHODS AND RESULTS: RFCA registries from 3 cardiovascular centers in Republic of Korea consisted of 5,721 patients undergoing 6,724 procedures. Before undergoing RFCA, patients underwent either computed tomography or magnetic resonance imaging. We evaluated clinical, anatomical, and procedural characteristics of patients who developed AE fistula after RFCA...
June 21, 2018: Journal of Cardiovascular Electrophysiology
Stefania Paolillo, Piergiuseppe Agostoni, Fabiana De Martino, Francesca Ferrazzano, Fabio Marsico, Paola Gargiulo, Elisabetta Pirozzi, Caterina Marciano, Santo Dellegrottaglie, Pasquale Perrone Filardi
Exercise intolerance is a typical manifestation of patients affected by heart failure with reduced ejection fraction (HFrEF); however, the relationship among functional capacity, mortality, and exercise-induced heart rate response during exercise remains unclear in either sinus rhythm or atrial fibrillation subjects. Heart rate increase during incremental load exercise has a typical pattern in normal subjects, whereas it is commonly compromised in HFrEF patients, mainly due to the imbalance of the autonomic nervous system...
July 2018: Heart Failure Reviews
Jeroen M Hendriks, Celine Gallagher, Melissa E Middeldorp, Prashanthan Sanders
No abstract text is available yet for this article.
June 20, 2018: Heart: Official Journal of the British Cardiac Society
Y H Li, Z Tholakanahalli, J M Adabag, Zhong Wang, Jianming Li
Objective: To investigate the accuracy of arrhythmia detection algorithm and the effectiveness of Reveal LINQ insertable cardiac monitor (ICM). Methods: This single-center, descriptive, non-controlled clinical study was designed to enroll consecutive patients who were implanted with Reveal LINQ ICM in Minneapolis Veterans Affairs Medical Center from June 19, 2014 to April 18, 2017. The safety of implant procedure, the accuracy of automatic arrhythmia detection algorithm and the clinical effectiveness were evaluated and validated independently by two physicians...
June 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
Kunal Pradip Verma, David Adam
A 62 year old male presented to his treating cardiologist for routine interrogation of his implantable cardiac defibrillator (ICD) on the background of severe ischaemic cardiomyopathy and end-stage kidney disease on haemodialysis. The device log revealed multiple paroxysms of atrial fibrillation (AF); however, upon scrutinising these episodes it was evident that they always corresponded to episodes of haemodialysis whilst dialysing through a chronic dialysis catheter, but not whilst dialysing via an arteriovenous fistula...
June 20, 2018: Pacing and Clinical Electrophysiology: PACE
Christian-Hendrik Heeger, Christopher Schuette, Valentina Seitelberger, Erik Wissner, Andreas Rillig, Shibu Mathew, Bruno Reissmann, Christine Lemes, Tilman Maurer, Thomas Fink, Osamu Inaba, Naotaka Hashiguchi, Francesco Santoro, Feifan Ouyang, Karl-Heinz Kuck, Andreas Metzner
BACKGROUND: The second-generation cryoballoon (CB2) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging and reproducible clinical outcome data. The latest-generation cryoballoon (CB3) incorporates a 40% shorter distal tip, thus allowing for an increased rate of PVI real-time signal recording and facilitating individualized ablation strategies taking the time-to-effect (TTE) into account. However, whether this characteristic translates into favorable clinical success has not been evaluated yet...
June 20, 2018: Cardiology Journal
Aleksandra Liżewska-Springer, Alicja Dąbrowska-Kugacka, Ewa Lewicka, Łukasz Drelich, Tomasz Królak, Grzegorz Raczak
BACKGROUND: Catheter ablation (CA) is a well-known treatment option for patients with symptomatic drug-resistant atrial fibrillation (AF). Multiple factors have been identified to determine AF recurrence after CA, however their predictive value is rather small. Identification of novel predictors of CA outcome is therefore of primary importance to reduce health costs and improve long-term results of this intervention. The recurrence of AF following CA is related to the severity of left ventricular (LV) dysfunction, extend of atrial dilatation and fibrosis...
June 20, 2018: Cardiology Journal
Madhukar Kollengode, Jehu Mathew, Elizabeth Yeung, William H Sauer, Duy Thai Nguyen
No abstract text is available yet for this article.
June 2018: HeartRhythm Case Reports
Shankar Baskar, Mehran Attari, Richard J Czosek, Pierre Jais, Jeffrey B Anderson, David S Spar
No abstract text is available yet for this article.
June 2018: HeartRhythm Case Reports
Lasse Skibsbye, Anne K Bengaard, A M Uldum-Nielsen, Kim Boddum, Torsten Christ, Thomas Jespersen
Sympathetic and vagal activation is linked to atrial arrhythmogenesis. Here we investigated the small conductance Ca2+ -activated K+ (SK)-channel pore-blocker N -(pyridin-2-yl)-4-(pyridine-2-yl)thiazol-2-amine (ICA) on action potential (AP) and atrial fibrillation (AF) parameters in isolated rat atria during β-adrenergic [isoprenaline (ISO)] and muscarinic M2 [carbachol (CCh)] activation. Furthermore, antiarrhythmic efficacy of ICA was benchmarked toward the class-IC antiarrhythmic drug flecainide (Fleca)...
2018: Frontiers in Physiology
Yufang Gao, Yuxiu Liu, Hui Zhang, Fang Fang, Lei Song
Background: Tip position verification of peripherally inserted central catheters (PICCs) is essential to the use of the catheter. Postprocedural chest X-ray as the "gold standard" practice for PICC tip confirmation can lead to a significant delay for patient IV therapy, cost more, and lead to radiation exposure for both patients and staffs. Intracavitary electrocardiogram (IC-ECG)-guided PICC placement which provides real-time tip confirmation during the insertion procedure has been widely used...
2018: Therapeutics and Clinical Risk Management
Jiachen Luo, Liming Dai, Jianming Li, Jinlong Zhao, Zhiqiang Li, Xiaoming Qin, Hongqiang Li, Baoxin Liu, Yidong Wei
Purpose: New-onset atrial fibrillation (NOAF) is a common finding in patients with myocardial infarction (MI), but few studies are available regarding the prediction model for its risk estimation. Although Global Registry of Acute Coronary Events (GRACE) risk score (RS) has been recognized as an effective tool for the risk evaluation of clinical outcomes in patients with MI, its usefulness in the prediction of post-MI NOAF remains unclear. In this study, we sought to validate the discrimination performance of GRACE RS in the prediction of post-MI NOAF and to make a comparison with that of the CHA2 DS2 -VASc score in patients with ST-segment elevation myocardial infarction (STEMI)...
2018: Clinical Interventions in Aging
Zuhair Iftikhar, Olli Lahdenoja, Mojtaba Jafari Tadi, Tero Hurnanen, Tuija Vasankari, Tuomas Kiviniemi, Juhani Airaksinen, Tero Koivisto, Mikko Pänkäälä
Cardiac translational and rotational vibrations induced by left ventricular motions are measurable using joint seismocardiography (SCG) and gyrocardiography (GCG) techniques. Multi-dimensional non-invasive monitoring of the heart reveals relative information of cardiac wall motion. A single inertial measurement unit (IMU) allows capturing cardiac vibrations in sufficient details and enables us to perform patient screening for various heart conditions. We envision smartphone mechanocardiography (MCG) for the use of e-health or telemonitoring, which uses a multi-class classifier to detect various types of cardiovascular diseases (CVD) using only smartphone's built-in internal sensors data...
June 19, 2018: Scientific Reports
Danny Varedi, Tibor Kovacsovics, Erinn Downs Kelly, Jo Abraham, Jared Cowley, Kelsey Barrell, Monica P Revelo, Josef Stehlik, Stavros Drakos, Nassir Marrouche, Brent Wilson, Eric A Swanson, James Fang, Jose Nativi-Nicolau
No abstract text is available yet for this article.
July 2018: Circulation. Heart Failure
David Calvo, David Filgueiras-Rama, José Jalife
Atrial fibrillation is a highly prevalent cardiac arrhythmia and the most important cause of embolic stroke. Although genetic studies have identified an increasing assembly of AF-related genes, the impact of these genetic discoveries is yet to be realized. In addition, despite more than a century of research and speculation, the molecular and cellular mechanisms underlying AF have not been established, and therapy for AF, particularly persistent AF, remains suboptimal. Current antiarrhythmic drugs are associated with a significant rate of adverse events, particularly proarrhythmia, which may explain why many highly symptomatic AF patients are not receiving any rhythm control therapy...
July 2018: Pharmacological Reviews
Elizabeth M Colwell, Carlos O Encarnacion, Lisa E Rein, Aniko Szabo, George Haasler, Mario Gasparri, William Tisol, David Johnstone
BACKGROUND: There have been numerous studies regarding atrial fibrillation (AF) associated with cardiac and pulmonary surgery; however, studies looking at esophagectomy and atrial fibrillation are sparse. The goal of this study was to review our institution's atrial fibrillation rate following esophagectomy in order to better define the incidence and predisposing factors in this patient population. METHODS: A retrospective chart review of all patients undergoing esophagectomy with transcervical endoscopic mobilization of the esophagus (TEEM) at the Medical College of Wisconsin and Affiliated Hospitals from July 2009 through December 2012...
June 19, 2018: Journal of Cardiothoracic Surgery
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