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https://www.readbyqxmd.com/read/29344701/the-fate-of-immunocompromised-patients-in-the-treatment-of-chronic-periprosthetic-joint-infection-a-single-centre-experience
#1
Baochao Ji, Xiaogang Zhang, Boyong Xu, Jiangdong Ren, Wentao Guo, Wenbo Mu, Li Cao
PURPOSE: Immunocompromised patients with periprosthetic joint infection (PJI) are rare and currently there are no reliable guidelines according to which these infections can be successfully managed. The purpose of this study was to report the clinical course of different strategies for treatment of PJI in frail patients. METHODS: A retrospective analysis between 2004 and 2015 included 29 immunocompromised patients (13 hips and 16 knees) with chronic PJI who underwent one-stage revision or debridement, antibiotics and implant retention (DAIR)...
January 17, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29337583/sudden-death-aversion-avoiding-superior-options-because-they-feel-riskier
#2
Jesse Walker, Jane L Risen, Thomas Gilovich, Richard Thaler
We present evidence of sudden-death aversion (SDA)-the tendency to avoid "fast" strategies that provide a greater chance of success, but include the possibility of immediate defeat, in favor of "slow" strategies that reduce the possibility of losing quickly, but have lower odds of ultimate success. Using a combination of archival analyses and controlled experiments, we explore the psychology behind SDA. First, we provide evidence for SDA and its cost to decision makers by tabulating how often NFL teams send games into overtime by kicking an extra point rather than going for the 2-point conversion (Study 1) and how often NBA teams attempt potentially game-tying 2-point shots rather than potentially game-winning 3-pointers (Study 2)...
January 15, 2018: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/29304013/breastfeeding-determinants-in-healthy-term-newborns
#3
Lorenzo Colombo, Beatrice Letizia Crippa, Dario Consonni, Maria Enrica Bettinelli, Viola Agosti, Giulia Mangino, Elena Nicoletta Bezze, Paola Agnese Mauri, Lidia Zanotta, Paola Roggero, Laura Plevani, Donatella Bertoli, Maria Lorella Giannì, Fabio Mosca
Breastfeeding is the normative standard for infant feeding. Despite its established benefits, different factors can affect breastfeeding rates over time. The purpose of this study was to evaluate breastfeeding determinants in healthy term newborns during the first three months of life. A prospective, observational, single-center study was conducted in the nursery of Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico in Milan, Italy. The mother-baby dyads that were admitted to the Clinic in January and February 2017 were enrolled...
January 5, 2018: Nutrients
https://www.readbyqxmd.com/read/29298765/impact-of-financial-incentives-on-early-and-late-adopters-among-us-hospitals-observational-study
#4
Igna Bonfrer, Jose F Figueroa, Jie Zheng, E John Orav, Ashish K Jha
OBJECTIVE: To examine how hospitals that volunteered to be under financial incentives for more than a decade as part of the Premier Hospital Quality Incentive Demonstration (early adopters) compared with similar hospitals where these incentives were implemented later under the Hospital Value-Based Purchasing program (late adopters). DESIGN: Observational study. SETTING: 1189 hospitals in the USA (214 early adopters and 975 matched late adopters), using Hospital Compare data from 2003 through 2013...
January 3, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29276115/the-cost-effectiveness-of-total-hip-arthroplasty-in-patients-80-years-of-age-and-older
#5
Samuel T Kunkel, Matthew J Sabatino, Ravinder Kang, David S Jevsevar, Wayne E Moschetti
BACKGROUND: This study investigates the cost-effectiveness of total hip arthroplasty (THA) in patients 80 years old. METHODS: A Markov, state-transition model projecting lifetime costs and quality-adjusted life years (QALYs) was constructed to determine cost-effectiveness from a societal perspective. Costs (in 2016 US dollars), health state utilities, and state transition probabilities were obtained from published literature. Primary outcome was incremental cost-effectiveness ratio, with a willingness-to-pay threshold of $100,000/QALY...
December 5, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29246613/clinical-management-of-tardive-dyskinesia-five-steps-to-success
#6
REVIEW
Leslie Citrome
Tardive dyskinesia (TD) has long been thought to be a generally irreversible consequence of the use of dopamine receptor blocking agents. There is now an opportunity to successfully manage this condition with agents approved by the US Food and Drug Administration. This is important because TD has not been eliminated with the use of second-generation antipsychotics, and the expansion of antipsychotics to treat conditions other than schizophrenia has resulted in millions of additional individuals at risk for developing TD...
December 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29241444/willingness-to-pay-for-flexible-working-conditions-of-people-with-type-2-diabetes-discrete-choice-experiments
#7
M A Nexo, B Cleal, Lise Hagelund, I Willaing, K Olesen
BACKGROUND: The increasing number of people with chronic diseases challenges workforce capacity. Type 2 diabetes (T2D) can have work-related consequences, such as early retirement. Laws of most high-income countries require workplaces to provide accommodations to enable people with chronic disabilities to manage their condition at work. A barrier to successful implementation of such accommodations can be lack of co-workers' willingness to support people with T2D. This study aimed to examine the willingness to pay (WTP) of people with and without T2D for five workplace initiatives that help individuals with type 2 diabetes manage their diabetes at work...
December 15, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29239578/national-vaccination-program-a-success-story-of-public-health-and-economy
#8
Heini Salo, Terhi Kilpi
The savings in treatment costs generated by disease cases prevented by the national vaccination program exceed the costs of the vaccination program by at least 60 million euros. In addition, other costs due to contracting the illness are avoided. Vaccinations serve the purpose of both increasing well-being and releasing resources for other uses. Financial support of vaccinations through the health insurance system would be costly and targetted to those with the ability to pay. Public funds should be directed to the development of a vaccination program...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29194905/mental-health-nurses-and-mental-health-peer-workers-self-perceptions-of-role-related-clinical-competences
#9
Bart Debyser, Veerle Duprez, Dimitri Beeckman, Joeri Vandewalle, Ann Van Hecke, Eddy Deproost, Sofie Verhaeghe
In a mental healthcare that embraces a recovery-oriented practice, the employment of mental health peer workers is encouraged. Although peer workers are increasingly working together with nurses, there is a lack of research that explores how nurses and peer workers perceive their role-related competences in clinical practice. The aim of this study was to clarify and understand these self-perceptions in order to identify the specificity and potential complementarity of both roles. This insight is needed to underpin a successful partnership between both vocations...
December 1, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29187640/generative-models-for-network-neuroscience-prospects-and-promise
#10
REVIEW
Richard F Betzel, Danielle S Bassett
Network neuroscience is the emerging discipline concerned with investigating the complex patterns of interconnections found in neural systems, and identifying principles with which to understand them. Within this discipline, one particularly powerful approach is network generative modelling, in which wiring rules are algorithmically implemented to produce synthetic network architectures with the same properties as observed in empirical network data. Successful models can highlight the principles by which a network is organized and potentially uncover the mechanisms by which it grows and develops...
November 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29180831/internal-conflict-market-uniformity-and-transparency-in-price-competition-between-teams
#11
Michael Kurschilgen, Alexander Morell, Ori Weisel
The way profits are divided within successful teams imposes different degrees of internal conflict. We experimentally examine how the level of internal conflict, and whether such conflict is transparent to other teams, affects teams' ability to compete vis-à-vis each other, and, consequently, market outcomes. Participants took part in a repeated Bertrand duopoly game between three-player teams which had either the same or different level of internal conflict (uniform vs. mixed). Profit division was either private-pay (high conflict; each member received her own asking price) or equal-pay (low conflict; profits were divided equally)...
December 2017: Journal of Economic Behavior & Organization
https://www.readbyqxmd.com/read/29174479/practical-implementation-education-and-interpretation-guidelines-for-continuous-glucose-monitoring-a-french-position-statement
#12
S Borot, P Y Benhamou, C Atlan, E Bismuth, E Bonnemaison, B Catargi, G Charpentier, A Farret, N Filhol, S Franc, D Gouet, B Guerci, I Guilhem, C Guillot, N Jeandidier, M Joubert, V Melki, E Merlen, A Penfornis, S Picard, E Renard, Y Reznik, J P Riveline, S Rudoni, P Schaepelynck, A Sola-Gazagnes, N Tubiana-Rufi, O Verier-Mine, H Hanaire
The use by diabetes patients of real-time continuous interstitial glucose monitoring (CGM) or the FreeStyle Libre® (FSL) flash glucose monitoring (FGM) system is becoming widespread and has changed diabetic practice. The working group bringing together a number of French experts has proposed the present practical consensus. Training of professionals and patient education are crucial for the success of CGM. Also, institutional recommendations must pay particular attention to the indications for and reimbursement of CGM devices in populations at risk of hypoglycaemia...
November 11, 2017: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29173145/histamine-h3-receptor-ligands-in-the-group-of-homo-piperazine-derivatives
#13
Katarzyna Szczepanska, Kamil Kuder, Katarzyna Kiec-Kononowicz
Since its' discovery in 1983, followed by gene cloning in 1999, the histamine H3 receptor served as an outstanding target for drug discovery. The wide spectrum of possible therapeutic implications make H3R's one of the most researched areas in the vast GPCR ligands field - started from imidazole containing ligands, through various successful imidazole replacements, with recent introduction of Wakix® to pharmaceutical market. One of such replacements is piperazine moiety, a significant versatile scaffold in rational drug design for most of the GPCR ligands...
November 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29148343/lessons-learned-from-the-affordable-care-act-the-premium-subsidy-design-may-promote-adverse-selection
#14
Ilana Graetz, Caitlin N McKillop, Cameron M Kaplan, Teresa M Waters
Since 2014, average premiums for health plans available in the Affordable Care Act marketplaces have increased. We examine how premium price changes affected the amount consumers pay after subsidies for the lowest-cost bronze and silver plans available by age in the federally facilitated exchanges. Between 2015 and 2016, benchmark plan premiums increased in 83.3% of counties. Overall, rising benchmark premiums were associated with lower average after-subsidy premiums for the lowest-cost bronze and silver plans for older subsidy-eligible adults, but with higher after-subsidy premiums for younger adults purchasing the same plans, regardless of income...
May 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29141837/user-acceptance-of-wrist-worn-activity-trackers-among-community-dwelling-older-adults-mixed-method-study
#15
Arjun Puri, Ben Kim, Olivier Nguyen, Paul Stolee, James Tung, Joon Lee
BACKGROUND: Wearable activity trackers are newly emerging technologies with the anticipation for successfully supporting aging-in-place. Consumer-grade wearable activity trackers are increasingly ubiquitous in the market, but the attitudes toward, as well as acceptance and voluntary use of, these trackers in older population are poorly understood. OBJECTIVE: The aim of this study was to assess acceptance and usage of wearable activity trackers in Canadian community-dwelling older adults, using the potentially influential factors as identified in literature and technology acceptance model...
November 15, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29102087/availability-cost-and-prescription-patterns-of-antihypertensive-medications-in-primary-health-care-in-china-a-nationwide-cross-sectional-survey
#16
Meng Su, Qiuli Zhang, Xueke Bai, Chaoqun Wu, Yetong Li, Elias Mossialos, George A Mensah, Frederick A Masoudi, Jiapeng Lu, Xi Li, Sebastian Salas-Vega, Anwen Zhang, Yuan Lu, Khurram Nasir, Harlan M Krumholz, Lixin Jiang
BACKGROUND: Around 200 million adults in China have hypertension, but few are treated or achieve adequate control of their blood pressure. Available and affordable medications are important for successfully controlling hypertension, but little is known about current patterns of access to, and use of, antihypertensive medications in Chinese primary health care. METHODS: We used data from a nationwide cross-sectional survey (the China Patient-Centered Evaluative Assessment of Cardiac Events Million Persons Project primary health care survey), which was undertaken between November, 2016 and May, 2017, to assess the availability, cost, and prescription patterns of 62 antihypertensive medications at primary health-care sites across 31 Chinese provinces...
October 25, 2017: Lancet
https://www.readbyqxmd.com/read/29096598/cost-effectiveness-analysis-of-a-sealing-hemostat-patch-hemopatch-vs-standard-of-care-in-cardiac-surgery
#17
Shelly Ikeme, Luca Weltert, Kevin M Lewis, Gerhard Bothma, Daniela Cianciulli, Nicole Pay, Josh Epstein, Erik Kuntze
BACKGROUND: A recent randomized controlled trial showed that patients undergoing ascending aorta surgery treated with HEMOPATCH to control bleeding had a significantly better hemostasis success rate than with dry or wet gauze compression or similar standard of care (SOC). OBJECTIVE: To compare the cost-effectiveness using two different agents for hemostasis (HEMOPATCH vs dry or wet gauze compression or similar SOC) in cardiac surgery from the European hospital perspective...
December 7, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29084160/new-instrument-to-measure-hospital-patient-experiences-in-flanders
#18
Luk Bruyneel, Else Tambuyzer, Ellen Coeckelberghs, Dirk De Wachter, Walter Sermeus, Dirk De Ridder, Dirk Ramaekers, Ilse Weeghmans, Kris Vanhaecht
Implementing a standardized patient experience survey may initiate a process to apply pressure on hospitals to attend to improving patient experiences. In Flanders, Belgium, the Flemish Patient Survey was developed between 2011 and 2015. A preliminary version was developed from a scoping review and patient and expert focus groups, and included 27 items for eight hypothesized dimensions: 'preparing for hospital stay', 'information and communication', 'coordination', 'respect', 'privacy', 'safe care', pain management', and 'participation'...
October 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29075429/a-feasibility-study-of-ssvep-based-passive-training-on-an-ankle-rehabilitation-robot
#19
Xiangfeng Zeng, Guoli Zhu, Lan Yue, Mingming Zhang, Shane Xie
OBJECTIVE: This study aims to establish a steady-state visual evoked potential- (SSVEP-) based passive training protocol on an ankle rehabilitation robot and validate its feasibility. METHOD: This paper combines SSVEP signals and the virtual reality circumstance through constructing information transmission loops between brains and ankle robots. The robot can judge motion intentions of subjects and trigger the training when subjects pay their attention on one of the four flickering circles...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29062749/transcatheter-aortic-valve-implantation-in-nonagenarians-selectively-feasible-or-extravagantly-futile
#20
Antonis S Manolis, Antonis A Manolis
A growing number of nonagenarians is recorded as life expectancy increases. Unfortunately, this extreme-aged group is plagued by increased prevalence of aortic stenosis amidst a higher occurrence of comorbidities that pose dilemmas to cardiologists and cardiac surgeons when having to choose a conservative or interventional treatment modality, and a surgical or transcatheter aortic valve implantation (TAVI) approach. TAVI is an expensive procedure, which also confers a higher mortality and morbidity risk in nonagenarians, compared to younger patients...
September 2017: Annals of Cardiothoracic Surgery
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