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Chil development

Seon Chil Kim, Jeong Ryeol Choi, Byeong Kyou Jeon
The purpose of this paper is to develop a lightweight apron that will be used for shielding low intensity radiation in medical imaging radiography room and to apply it to a custom-made effective shielding. The quality of existing aprons made for protecting our bodies from direct radiation are improved so that they are suitable for scattered X-rays. Textiles that prevent bodies from radiation are made by combining barium sulfate and liquid silicon. These materials have the function of shielding radiation in a manner like lead...
2016: Scientific Reports
Min Jeong Kim, U Suk Jung, Seung Woo Jeon, Jae Sung Lee, Won Seob Kim, Sang Bum Lee, Youn Chil Kim, Bae Young Kim, Tao Wang, Hong Gu Lee
This study was conducted to examine the effects of adding phytoncide oil extracted from Korean pine nut cone by-product to the diet of dairy cows on milk yield and compositions, fatty acid characteristics, complete blood count and stress response. A total of 74 Holstein cows were used for 30 days and divided into two groups. Each group was given a basal diet (C) or an experimental diet containing phytoncide additives at 0.016% (T) in feed. The results showed that phytoncide feeding had no effect on milk yield...
June 30, 2016: Asian-Australasian Journal of Animal Sciences
Masaaki Nakamura, Shiun-Jr Yang, Po-Yu Tsai, Toshio Kasai, King-Chuen Lin, Dock-Chil Che, Andrea Lombardi, Federico Palazzetti, Vincenzo Aquilanti
Molecular orientation is a fundamental requisite in the study of stereodirected dynamics of collisional and photoinitiated processes. In this past decade, variable hexapolar electric filters have been developed and employed for the rotational-state selection and the alignment of molecules of increasing complexity, for which the main difficulties are their mass, their low symmetry, and the very dense rotational manifold. In this work, for the first time, a complex molecule such as 2-bromobutane, an asymmetric top containing a heavy atom (the bromine), was successfully oriented by a weak homogeneous field placed downstream from the hexapolar filter...
July 14, 2016: Journal of Physical Chemistry. A
Zhiguang Wu, Tuanjun Hu, Lisa Rothwell, Lonneke Vervelde, Pete Kaiser, Kay Boulton, Matthew J Nolan, Fiona M Tomley, Damer P Blake, David A Hume
In mammals, the inducible cytokine interleukin 10 is a feedback negative regulator of inflammation. To determine the extent to which this function is conserved in birds, recombinant chicken IL-10 was expressed as a secreted human Ig Fc fusion protein (chIL-10-Fc) and used to immunise mice. Five monoclonal antibodies (mAb) which specifically recognise chicken IL-10 were generated and characterised. Two capture ELISA assays were developed which detected native chIL-10 secreted from chicken bone marrow-derived macrophages (chBMMs) stimulated with lipopolysaccharide (LPS)...
October 2016: Developmental and Comparative Immunology
Sun Min Lim, Byeong Bae Park, Keun-Chil Park, Hoon-Kyo Kim, Jong Seok Lee, Sung Hwa Bae, Seung-Sei Lee, Jin-Hyoung Kang, Se-Hoon Park, Gyeong-Won Lee, Hyo-Rac Lee, Jae Hong Seo, Yong Tae Kim, Sung Hyun Yang, Joo-Hang Kim
BACKGROUND: To investigate the efficacy, safety, and tolerability of weekly docetaxel treatment in advanced non-small cell lung cancer (NSCLC) patients in Korea. METHODS: This prospective observational study included Korean advanced NSCLC patients with Eastern Cooperative Oncology Group performance status <2 who received weekly monotherapy of docetaxel at a dose determined by the physician. Efficacy measurements included tumor response rate, overall survival (OS), progression-free survival, and one-year survival rate...
March 2016: Thoracic Cancer
Zhanjun Yang, Mimi Lu, Juan Li, Zining Tan, Hua Dai, Xin'an Jiao, Xiaoya Hu
Chicken interleukin-4 (ChIL-4), which is released by activated type 2 helper (Th2) cells following their stimulation in vitro, is an important indicator for the study of cell-mediated immunity in chickens after infection or vaccination. In this work, the first ChIL-4 chemiluminescent (CL) immunosensor was developed via the immobilization of monoclonal ChIL-4 antibodies on a nitrogen-doped graphene (NG)-chitosan nanocomposite matrix. NG nanosheets were used for the first time in the CL immunoassay to provide a biocompatible microenvironment for the immobilized capture antibody...
February 17, 2016: Biosensors & Bioelectronics
Jaehwan Kim, Chil-Hwan Oh, Jiehyun Jeon, Yoosang Baek, Jaewoo Ahn, Dong Joo Kim, Hyun-Soo Lee, Joel Correa da Rosa, Mayte Suárez-Fariñas, Michelle A Lowes, James G Krueger
Psoriasis is present in all racial groups, but in varying frequencies and severity. Considering that small plaque psoriasis is specific to the Asian population and severe psoriasis is more predominant in the Western population, we defined Asian small and intermediate plaque psoriasis as psoriasis subtypes and compared their molecular signatures with the classic subtype of Western large plaque psoriasis. Two different characteristics of psoriatic spreading-vertical growth and radial expansion-were contrasted between subtypes, and genomic data were correlated to histologic and clinical measurements...
January 2016: Journal of Investigative Dermatology
Ping Tou Gee, Chen Yee Liew, Meng Chil Thong, Melvin C L Gay
We have developed a method for analysing vitamin E using ultra-performance convergence chromatography with a chromatographic runtime of 5.5 min. A well-resolved chromatogram with excellent precision in retention time revealed seven vitamin E components in the palm oil derived tocotrienol-rich fraction. The major vitamin E components were α-tocopherol, α-tocotrienol, γ-tocotrienol and δ-tocotrienol whereas the minor vitamin E components were α-tocomonoenol, β-tocotrienol and an unreported trace component...
April 1, 2016: Food Chemistry
Jaehwan Kim, Chil-Hwan Oh, Jiehyun Jeon, Yoosang Baek, Jaewoo Ahn, Dong Joo Kim, Hyun-Soo Lee, Joel Correa da Rosa, Mayte Suárez-Fariñas, Michelle A Lowes, James G Krueger
Psoriasis is present in all racial groups, but in varying frequencies and severity. Considering that small plaque psoriasis is specific to the Asian population and severe psoriasis is more predominant in the Western population, we defined Asian small and intermediate plaque psoriasis as psoriasis subtypes, and compared their molecular signatures with classic subtype of Western large plaque psoriasis. Two different characteristics of psoriatic spreading-vertical growth and radial expansion-were contrasted between subtypes, and genomic data were correlated to histologic and clinical measurements...
September 29, 2015: Journal of Investigative Dermatology
Marc Fiedler, Michael Graeb, Juliusz Mieszczanek, Trevor J Rutherford, Christopher M Johnson, Mariann Bienz
TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated by β-catenin following Wnt signaling. They control embryonic development and adult stem cell compartments, and their dysregulation often causes cancer. β-catenin-dependent transcription relies on the NPF motif of Pygo proteins. Here, we use a proteomics approach to discover the Chip/LDB-SSDP (ChiLS) complex as the ligand specifically binding to NPF. ChiLS also recognizes NPF motifs in other nuclear factors including Runt/RUNX2 and Drosophila ARID1, and binds to Groucho/TLE...
2015: ELife
Carlos M S Dutok, Clara Azalea Berenguer-Rivas, Elizabeth Rodríguez-Leblanch, Liliana Pérez-Jackson, Idelsy Chil-Nuñez, Julio César Escalona-Arranz, Bernardo Reyes-Tur, Margareth M C Queiroz
The common use of Pouteria mammosa (L.) Cronquist, "Mamey or Zapote," in food and ethnobotanic medicine shows its low or absent toxicity as fruit extracts prepared from seeds. However, it is essential to conduct security trials to scientifically support their use in drug therapy. This study evaluated the aqueous and hydroalcoholic extract (25%) Acute Oral Toxicity, obtained from the seeds of P. mammosa, in Sprague Dawley rats and dermal and eye irritability in New Zealand rabbits. The 404 and 405 acute dermal and eye irritation/corrosion guidelines were used, as well as the 423 Acute Oral Toxicity guideline, Acute Toxic Class Method of the Organization for Economic Cooperation and Development (OECD)...
2015: TheScientificWorldJournal
Andrzej Nowakowski, Marek Cybulski, Andrzej Śliwczyński, Arkadiusz Chil, Zbigniew Teter, Przemysław Seroczyński, Marc Arbyn, Ahti Anttila
BACKGROUND: Well-organised quality-controlled screening can substantially reduce the burden of cervical cancer (CC). European guidelines (EuG) for quality assurance in CC screening provide guidance on all aspects of an organised screening programme. Organised CC screening in Poland was introduced in 2007. The purpose of our study was to analyse: (i) adherence of the programme to EuG; (ii) programme process and performance indicators; (iii) impact of the programme on the incidence of and mortality from CC...
2015: BMC Cancer
Yi Zhang, Chil-Woo Lee, Nora Wehner, Fabian Imdahl, Veselova Svetlana, Christoph Weiste, Wolfgang Dröge-Laser, Rosalia Deeken
Virulent Agrobacterium tumefaciens strains integrate their T-DNA into the plant genome where the encoded agrobacterial oncogenes are expressed and cause crown gall disease. Essential for crown gall development are IaaH (indole-3-acetamide hydrolase), IaaM (tryptophan monooxygenase) and Ipt (isopentenyl transferase), which encode enzymes for the biosynthesis of auxin (IaaH, IaaM) and cytokinin (Ipt). Although these oncogenes are well studied as the tumor-inducing principle, nothing is known about the regulation of oncogene expression in plant cells...
January 2015: PLoS Pathogens
Chil Won Lee, Jun Yeob Lee
Three donor-acceptor type host materials with different photophysical properties were developed by managing the interconnect position of the donor and acceptor moieties and molecular structure of the host materials was correlated with the electro-optical properties and device performances of the host materials. The linkage via the meta-position of aromatic units was better than the linkage via ortho- or para-positions and high quantum efficiency of 26.0% in the green thermally activated delayed fluorescent device was achieved using the host material with the meta-linkage...
February 4, 2015: ACS Applied Materials & Interfaces
Katarzyna Szatraj, Agnieszka K Szczepankowska, Violetta Sączyńska, Katarzyna Florys, Beata Gromadzka, Krzysztof Łepek, Grażyna Płucienniczak, Bogusław Szewczyk, Włodzimierz Zagórski-Ostoja, Jacek Bardowski
Gram-positive and nonpathogenic lactic acid bacteria (LAB) are considered to be promising candidates for the development of new, safe systems of heterologous protein expression. Recombinant LAB has been shown to induce specific local and systemic immune response against selected pathogens, and could be a good alternative to classical attenuated carriers. The main goal of our study was to express the avian influenza haemagglutinin (H5) and chicken interleukin 2 (chIL-2) in Lactococcus lactis. Results of this study were anticipated to lead to construction of lactococcal strain(s) with potential vaccine properties against the avian influenza A (H5N1) virus...
2014: Acta Biochimica Polonica
Soon-Cheol Chung, Mi-Hyun Choi, Sung-Jun Park, Jung-Chul Lee, Ul-Ho Jeong, Ji-Hye Baek, Ji-Hye You, Young Chil Choi, Dae-Woon Lim, Jeong-Han Yi, Hyung-Sik Kim
In this study, a tactile stimulator that could separately or simultaneously display the vibrotactile and pressure sense was developed. The developed system consisted of a control unit, a drive unit, and an actuator, and can be operated with PC or manually. This system quantitatively controls the stimulation parameters such as the stimulation intensity, duration, frequency, and stimulation type. A preliminary electroencephalogram (EEG) experiment for three types of stimulation (vibrotactile, pressure sense, vibrotactile + pressure sense) highlights that the system could be used in complex tactile cognitive studies...
2014: Bio-medical Materials and Engineering
S H Lee, H S Lillehoj, M S Jeong, E Del Cacho, J B Kim, H R Kim, W Min, H Y Jeoung, D J An
Interleukin-1β proteins from chicken, duck, goose, turkey, and pigeon share 77 to 99% amino acid sequence similarity among themselves, and only 31 to 35% sequence similarity is shared between avian and mammalian IL-1β. There have been no antibodies that specifically detect avian IL-1β, and the current study was conducted to develop mouse monoclonal antibodies (mAb) against chicken IL-1β (chIL-1β) to further define its biochemical and immunological properties. In this study, 2 mouse mAb that are specific for chIL-1β were produced and characterized...
September 2014: Poultry Science
Jae-Ryung Cha, Chil-Won Lee, Myoung-Seon Gong
Blue light-emitting spiro[benzotetraphene-fluorene] (SBTF)-based host materials, 3-(1-naphthyl)-10-naphthylspiro[benzo[ij]tetraphene-7,9'-fluorene] (1), 3-(2-naphthyl)-10-naphthylspiro[benzo[ij]tetraphene-7,9'-fluorene] (2), and 3-[2-(6-phenyl)naphthyl]-10-naphthylspiro[benzo[ij]tetraphene-7,9'-fluorene] (3) were designed and prepared via multi-step Suzuki coupling reactions. Introducing various aromatic groups into SBTF core lead to a reduction in band gap and a determination of the color purity and luminescence efficiency...
July 2014: Journal of Fluorescence
Juneyoung Heo, Sukh Que Park, Sung Jin Cho, Jae Chil Chang, Hyung-Ki Park
OBJECT: Some patients with severe brain swelling treated with decompressive craniectomy may develop hydrocephalus. Consequently, these patients require cranioplasty and a ventriculoperitoneal (VP) shunt to relieve the hydrocephalus. However, there is no consensus as to the timing of the cranioplasty and VP shunt placement in patients requiring both. The authors assessed the results of performing cranioplasty and VP shunt placement at the same time in patients with cranial defects and hydrocephalus...
August 2014: Journal of Neurosurgery
Federico Palazzetti, Glauciete S Maciel, Keita Kanda, Masaaki Nakamura, Dock-Chil Che, Toshio Kasai, Vincenzo Aquilanti
Selection and alignment of rotamers and, more in general, of conformers in the gas phase is a challenge that we tackle experimentally by supersonic expansion of seeded molecular beams and hexapolar electrostatic fields with quadrupole mass detection. The studied system involves the nine conformers of the asymmetric-top molecule 2-butanol, which coexist because of nearly free rotations around a CC and a CO bond. From the measured time-of-flight of a 2-butanol supersonic molecular beam seeded in either He or Ar, the corresponding velocity distributions are obtained...
June 7, 2014: Physical Chemistry Chemical Physics: PCCP
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