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prick test

Dilara Fatma Kocacık Uygun, Serkan Filiz, Ayşen Bingöl
Background/aim: We aimed to apply a double-blind placebo-controlled food challenge (DBPCFC) test to patients who reported a reaction to banana and showed positivity for banana-specific IgE in Turkey. Materials and methods: Medical data of patients who had been analyzed for banana allergy were reviewed, focusing on banana-specific IgE positivity at the Department of Pediatric Allergy-Immunology at the Akdeniz University Faculty of Medicine between the years 2004 and 2012. Patients were called to the clinic for a DBPCFC test...
June 14, 2018: Turkish Journal of Medical Sciences
D Demant, K Lund, B Christensen, M Segerdahl, N Sjögren, T S Jensen, S Sindrup, N B Finnerup
Background In patients with neuropathic pain, Quantitative Sensory Testing (QST) can define different sensory phenotypes thought to be related to different underlying mechanisms. One phenotype with abnormal sensitization of cutaneous nociceptors has been termed irritable nociceptors. Methods This study is a part of a randomized, double-blind, placebo controlled, crossover trial with the anticonvulsant oxcarbazepine. The study is ongoing. In this report, baseline QST measures from patients with peripheral neuropathic pain due to either polyneuropathy (PNP) or peripheral nerve injury (PNI) are analyzed...
December 29, 2017: Scandinavian Journal of Pain
Wang Wanjun, Hu Qiurong, Xie Yanqing, Xian Mo, Wei Nili, Li Jing
Background The results of skin and blood allergen testing are not consistently relevant to clinical manifestations in allergic patients. Objective The aim of the study was to investigate the relationship between severity of allergic rhinitis and different allergen diagnostic tests in Dermatophagoides species-sensitized patients. Methods Study subjects included 65 rhinitis patients-50 with Dermatophagoides pteronyssinus (DP) sensitization (DP+) and 15 without DP sensitization (DP-), and 15 DP+ and 37 DP- healthy controls (HCs) confirmed by allergen skin prick (SPT) and blood specific immunoglobulin E (sIgE) tests...
January 1, 2018: American Journal of Rhinology & Allergy
Santosh Modani, Davala Krishna Karthik, Shruti Heda, Anirudda Deshpande
We report a 57-year-old man presenting with symptoms of sharp pricking, exertional retrosternal chest pain multiple times, each episode lasting for a few seconds. On evaluation, the ECG of the patient showed normal sinus rhythm with T wave inversions in leads V1-V3. Troponin T test was negative. Transthoracic echocardiography showed a globular mass in the interventricular septum. Cardiac MRI was suspicious of the lesion to be a hydatid cyst. Surgical excision of the lesion followed by histopathology was confirmatory of hydatid cyst...
June 15, 2018: BMJ Case Reports
Paloma Campo, Ibon Eguiluz-Gracia, Gador Bogas, María Salas, Carmen Plaza Serón, Natalia Pérez, C Mayorga, M J Torres, Mohammed Shamji, Carmen Rondon
A significant proportion of rhinitis patients without systemic IgE-sensitization tested by skin prick test and serum allergen-specific IgE (sIgE) display nasal reactivity upon nasal allergen provocation test (NAPT). This disease phenotype has been termed local allergic rhinitis (LAR). LAR is an underdiagnosed entity affecting children and adults from different parts of the world, with moderate-to-severe symptoms, impairment of quality of life and rapid progression to symptom worsening. LAR is a stable phenotype and not merely an initial state of AR...
June 14, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Leonardo Oliveira Mendonça, Cynthia Mafra Fonseca de Lima, Priscilla Rios Cordeiro Macedo, Victor do Espirito Santo Cunha, Ruppert Ludwig Hahnstadt, Jorge Kalil, Clóvis Eduardo Santos Galvão
CONTEXT: Adverse reactions associated with prick tests are rare but may be present as serious systemic reactions. CASE REPORT: A 38-year-old female nursing technician complained of three episodes of anaphylaxis in one year, all in the workplace. To investigate latex allergy, the patient underwent the prick test with latex, and immediately developed a rash, itchy skin, hoarseness, dyspnea and dry cough. Her condition improved promptly after appropriate measures were established for controlling her anaphylaxis...
June 11, 2018: São Paulo Medical Journal, Revista Paulista de Medicina
Sanjay Rastogi, Tousif Ahmed, Kolli Giri, Ramakant Dandriyal, Niranjana Prasad Indra B, Ankur Joshi, Shouvik Choudhury, Sunil Mall
The aim of this prospective study was to appraise the role of embrasure wiring in the treatment of mandibular fractures over the arch bar as adjunctive techniques of maxillomandibular fixation (MMF). This study was conducted on 40 patients who were surgically treated for mandibular fractures with accessory use of MMF (embrasure: group A vs. arch bars: group B). All patients were evaluated for demographic data, etiology, and location of fracture. Characteristically, the complications, including wire injury, infection, and malocclusion, were recorded...
June 2018: Craniomaxillofacial Trauma & Reconstruction
Lisbet Krogh Traulsen, Anders Halling, Jesper Bælum, Jesper Rømhild Davidsen, Martin Miller, Øyvind Omland, David Sherson, Torben Sigsgaard, Trine Thilsing, Gert Thomsen, Lars Rauff Skadhauge
Objective: The aim of the study was to evaluate determinants for the prognosis of asthma in a population-based cohort of young adults. Design: The study was a nine-year clinical follow up of 239 asthmatic subjects from an enriched population-based sample of 1,191 young adults, aged 20-44 years, who participated in an interviewer-administered questionnaire and clinical examination at baseline in 2003-2006. From the interview, an asthma score was generated as the simple sum of affirmative answers to five main asthma-like symptoms in order to analyse symptoms of asthma as a continuum...
2018: European Clinical Respiratory Journal
Alexandra Walter, Marlene Seegräber, Andreas Wollenberg
A wide variety of foods may cause or aggravate skin diseases such as contact dermatitis, contact urticaria, or atopic dermatitis (AD), both in occupational and private settings. The mechanism of action underlying allergic disease to food, food additives, and spices may be immunologic and non-immunologic. The classification and understanding of these reactions is a complex field, and knowledge of the possible reaction patterns and appropriate diagnostic test methods is essential. In addition, certain foods may cause worsening of atopic dermatitis lesions in children...
June 7, 2018: Clinical Reviews in Allergy & Immunology
Gemma Reverter-Branchat, Rosa Ventura, Mohammed Ezzel Din, Julián Mateus, Carme Pedro, Jordi Segura
The use of dried blood spots (DBS) for antidoping purposes would facilitate an increase in the number of blood samples because it eliminates the need of specialized personnel and involves minimal invasiveness, reduced costs, stability and easy transportation and storage. Here, the electrophoretic methodology established by the World Anti-Doping Agency (WADA) to detect Erythropoiesis Stimulating Agents (ESAs) has been adapted to evaluate their applicability to DBS. A qualitative procedure to detect recombinant erythropoietin (rEPO), novel erythropoiesis stimulating protein (NESP) and continuous erythropoietin receptor activator (CERA) in one single DBS was optimized and validated...
June 6, 2018: Drug Testing and Analysis
Jun Kido, Natsuko Nishi, Tomoaki Matsumoto
BACKGROUND: Many researchers have made efforts to develop diagnostic tools for predicting the outcome of oral food challenges (OFCs). The aim of this study was to assess the diagnostic value of the skin prick test (SPT) and blood-specific IgE concentrations based on the outcome of the OFCs for heated and raw hen egg. METHODS: This study included 103 children with suspected hen egg allergy (HEA; median age 23 months, range 10-155; 72 boys, 31 girls). Forty-three patients were diagnosed with HEA by OFC...
June 6, 2018: International Archives of Allergy and Immunology
Muna Kamal, Sukhpreet K Tamana, Lisa Smithson, Linda Ding, Amanda Lau, Joyce Chikuma, Jennifer Mariasine, Diana L Lefebvre, Padmaja Subbarao, Allan B Becker, Stuart E Turvey, Malcolm R Sears, Jacqueline Pei, Piush J Mandhane
OBJECTIVE: Childhood sleep-disordered breathing (SDB) symptoms may comprise multiple phenotypes depending on craniofacial anatomy, tonsil and adenoid growth, body habitus, and rhinitis symptoms. The primary objective of this study is to identify and characterize the different SDB phenotypes to two years of age. METHODS: Data from 770 infants in the Edmonton sub-cohort of the Canadian Healthy Infant Longitudinal Study (CHILD) were analyzed to identify SDB phenotypes based on age of onset and duration of symptoms...
May 3, 2018: Sleep Medicine
Urs C Steiner, Lea Kölliker, Christina Weber-Chrysochoou, Peter Schmid-Grendelmeier, Elsbeth Probst, Walter A Wuillemin, Arthur Helbling
BACKGROUND: Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is a rare inherited disease. In most HAE-affected subjects, defined trigger factors precede angioedema attacks. Mechanisms of how trigger factors stimulate the contact activation pathway with bradykinin generation are not well elucidated. In recent studies, hypersensitivity reactions and food were stated as relevant triggers. We investigated HAE affected people for possible hypersensitivity reactions or intolerances and their relation in triggering angioedema attacks...
June 5, 2018: Orphanet Journal of Rare Diseases
Federica Tafuro, Luisella Selis, Matteo Goldoni, Mariarita Stendardo, Paola Mozzoni, Erminia Ridolo, Piera Boschetto, Massimo Corradi
OBJECTIVES: Laboratory animal allergy is a highly prevalent occupational disease among exposed workers. The aim of the study was to validate the biomarkers of airway inflammation in laboratory animal (LA) care workers. METHODS: All of the participants in this observational study (63 LA care workers and 64 controls) were administered a clinical questionnaire, underwent spirometry and a skin prick or radioallergosorbent test for common and occupational aeroallergens, and the fraction of exhaled nitric oxide (FeNO50 ), exhaled breath condensate hydrogen peroxide (EBC H2 O2 ) and serum pneumoprotein levels were measured...
June 1, 2018: International Archives of Occupational and Environmental Health
Sarah Micozzi, Sonsoles Infante, Victoria Fuentes-Aparicio, Alberto Álvarez-Perea, Lydia Zapatero
INTRODUCTION: Celiac disease and wheat allergy (WA) are infrequent diseases in the general population, and a combination of the 2 is particularly rare. Celiac disease occurs in around 1% of the general population and WA in around 1% of all children. CASE REPORT: We report 2 patients with celiac disease and a gluten-free diet who developed WA consistent in anaphylaxis and an eyelid angioedema, respectively, through accidental wheat exposure. A serum study and an intestinal biopsy confirmed celiac disease...
May 30, 2018: International Archives of Allergy and Immunology
Akili K Kalinga, Charles Mwanziva, Sarah Chiduo, Christopher Mswanya, Deus I Ishengoma, Filbert Francis, Lucky Temu, Lucas Mahikwano, Saidi Mgata, George Amoo, Lalaine Anova, Eyako Wurrapa, Nora Zwingerman, Santiago Ferro, Geeta Bhat, Ian Fine, Brian Vesely, Norman Waters, Mara Kreishman-Deitrick, Mark Hickman, Robert Paris, Edwin Kamau, Colin Ohrt, Reginald A Kavishe
BACKGROUND: Although microscopy is a standard diagnostic tool for malaria and the gold standard, it is infrequently used because of unavailability of laboratory facilities and the absence of skilled readers in poor resource settings. Malaria rapid diagnostic tests (RDT) are currently used instead of or as an adjunct to microscopy. However, at very low parasitaemia (usually < 100 asexual parasites/µl), the test line on malaria rapid diagnostic tests can be faint and consequently hard to visualize and this may potentially affect the interpretation of the test results...
May 29, 2018: Malaria Journal
Jelena Gotovina, Christina L Pranger, Annika N Jensen, Stefanie Wagner, Oswald D Kothgassner, Nadine Mothes-Luksch, Rupert Palme, Desirée Larenas-Linnemann, Jaswinder Singh, Ralph Mösges, Anna Felnhofer, Lisa-Maria Glenk, Erika Jensen-Jarolim
BACKGROUND & AIMS: The effects of acute stress on allergic symptoms are little understood. The intention of this clinical study was to study the effects of acute stress and related mediators in allergic rhinitis (AR), taking the wheal and flare reaction in skin prick testing (SPT) as a readout. METHODS: 19 healthy and 21 AR patients were first subjected to SPTs with grass pollen-, birch pollen- and house dust mite allergen extracts, histamine and negative control...
2018: PloS One
Z Z Cao, X X Zheng, B H Feng, J J Gao, S Y Huang, X Zhan, B L Li, B B Chen
Objective: To investigate the association between symptom of attention deficit/hyperactivity disorder (ADHD) and allergic rhinitis (AR) in children with AR at different sexes and different ages. Method: A total of 439 AR children aged 6 to 12 years were enrolled in this study. Basic information (age, gender, medical history, family history and comorbidities) of children with AR was collected. Results of prick tests on children skin were recorded. (TNSS) and Chinese version of the SNAP-Ⅳ scale, children under the guidance of independent completion of children's quality of life of children with nasal conjunctivitis scale (PRQLQ)...
February 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Z X Yin, Y Zhu, X Zhai, J L Zhang, G Liu
Objective: To investigate the clinical symptoms and immunology inspection characteristics of nasal cavity local allergy. Method: Selected 60 patients as observation group, who had only nasal local allergy symptoms, allergen skin prick test and serum allergen specific IgE (SIgE) test were negative, 40 allergic rhinitis (AR) patients and 40 healthy volunteers as control groups. To detect Symptom scores and VAS scores, and eosinophilia counts in venous blood, allergen skin prick test (SPT), serum allergen SIgE test, nasal secretions allergen SIgE test, nasal mucous membrane excitation test in both observation group and AR group, eosinophilia counts in nasal secretion, taked the data for statistical analysis...
August 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
H L Ren, J D Li, Y H Miao, T Xu
Objective: To investigate the clinical application of glass micro fiber basophil activation test (BAT) used as a complementary test for house dust mite allergen. Method: Forty patients with clinical diagnosed allergic rhinitis was test by three methods for house dust mite allergen, skin prick test(SPT),Immuno CAP sIgE, and BAT in vitro. The sensitivity and specificity of glass micro fiber were accessed, and the consistency between BAT, SPT, and Immuno sIgE was analyzed. As in vivo provocation was not performed, gold standard is regarded as the combination of medical history and positive reports of SPT and/or ImmunoCAP sIgE test...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
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