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https://www.readbyqxmd.com/read/28228160/assessment-of-lymphatic-filariasis-prior-to-re-starting-mass-drug-administration-campaigns-in-coastal-kenya
#1
Sammy M Njenga, Henry M Kanyi, Faith M Mutungi, Collins Okoyo, Hadley S Matendechero, Rachel L Pullan, Katherine E Halliday, Simon J Brooker, C Njeri Wamae, Joyce K Onsongo, Kimberly Y Won
BACKGROUND: Lymphatic filariasis (LF) is a debilitating disease associated with extensive disfigurement and is one of a diverse group of diseases referred to as neglected tropical diseases (NTDs) which mainly occur among the poorest populations. In line with global recommendations to eliminate LF, Kenya launched its LF elimination programme in 2002 with the aim to implement annual mass drug administration (MDA) in order to interrupt LF transmission. However, the programme faced financial and administrative challenges over the years such that sustained annual MDA was not possible...
February 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28226401/natural-evolution-in-patients-with-non-steroidal-anti-inflammatory-drugs-induced-urticaria-angioedema
#2
Inmaculada Doña, Esther Barrionuevo, María Salas, José Antonio Cornejo-García, James R Perkins, Gádor Bogas, Ana Prieto, María José Torres
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequent triggers of drug hypersensitivity with NSAIDs-induced urticaria/angioedema (NIUA) the most common phenotype. Loss of hypersensitivity has been reported for IgE-mediated reactions; however it has not been assessed in non-immunological reactions such as NIUA. We evaluated NSAID-hypersensitivity over time in NIUA patients. METHODS: Patients confirmed as NIUA by positive drug provocation test (DPT) with acetylsalicylic acid (ASA) during 2005-2012 (V1) were included (n=38)...
February 22, 2017: Allergy
https://www.readbyqxmd.com/read/28219166/-the-value-of-sinonasal-ct-scan-in-diagnosing-of-eosinophilic-chronic-rhinosinusitis-with-nasal-polyps
#3
Y F Meng, H F Lou, C S Wang, L Zhang
Objective: To compare the value of sinonasal CT scan with other clinical parameters in the pre-diagnosis of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP). Methods: From January to May of 2016, One hundred and fifty consecutive CRSwNP patients (90 eCRSwNP and 60 non-eosinophilic CRSwNP) undergoing endoscopic functional sinus surgery in Beijing Tongren Hospital were recruited in this study. Preoperative CT scan, skin prick test (SPT) and oral fractional exhaled nitric oxide (FeNO) measurements were performed in each patient and full blood count with differential analysis was performed within 1 week before surgery...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28217501/the-effects-of-meal-glycemic-load-on-blood-glucose-levels-of-adults-with-different-body-mass-indexes
#4
Tuba Yalçın, Ayhan Al, Neslişah Rakıcıoğlu
AIMS: The aim was to determine the effect of meal glycemic load (GL) on blood glucose levels of healthy people with different body mass indexes (BMIs). METHODS: Thirty healthy controls were included in this study. The participants were divided into two groups according to their BMI as normal group (BMI = 18.5-24.9 kg/m(2), n = 15) and overweight group (BMI = 25.0-29.9 kg/m(2), n = 15). Dietary assessment was done by the 24-h recall method for 3 successive days. Cases were fed by breakfasts with two different GL on consecutive days...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28214223/evaluation-of-a-field-test-for-antibodies-against-chlamydia-trachomatis-during-trachoma-surveillance-in-nepal
#5
Michelle J Sun, Andrea I Zambrano, Laura Dize, Beatriz Munoz, Sarah Gwyn, Sailesh Mishra, Diana L Martin, Shekhar Sharma, Sheila K West
PURPOSE: Testing for antibodies to Chlamydia trachomatis has potential as a surveillance tool. Our evaluation compares lateral flow assays (LFAs) during surveillance surveys in Nepal with Multiplex bead array (MBA). Fifty children were randomly sampled from each of 15 random clusters in two districts of Nepal. Finger prick blood samples were collected from 1509 children and tested onsite for anti-Pgp3 antibodies by LFA. The LFA was read at 30min as negative, positive, or invalid. Tests results were also rated as difficult to read ("equivocal")...
January 17, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28208225/indoor-fungal-diversity-in-primary-schools-may-differently-influence-allergic-sensitization-and-asthma-in-children
#6
João Cavaleiro Rufo, Joana Madureira, Inês Paciência, Lívia Aguiar, Cristiana Pereira, Diana Silva, Patrícia Padrão, Pedro Moreira, Luís Delgado, Isabella Annesi-Maesano, Eduardo Oliveira Fernandes, João Paulo Teixeira, André Moreira
BACKGROUND: Childhood exposure to microbiological agents may influence the development of allergic and respiratory diseases. Apart from home, children spend most of their time at school, which represents an environment of significant exposure to indoor air microbes. Therefore, we aimed to assess how the prevalence of allergic sensitization and asthma in schoolchildren is affected by microbiological exposure within classrooms. METHODS: Spirometry with bronchodilation, exhaled nitric oxide measurements and skin-prick tests data were retrieved from 858 children aged 8 to 10 years old attending 71 classrooms in 20 primary schools...
February 16, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28208220/allergic-respiratory-disease-different-allergens-different-symptoms
#7
Antonio Valero, Santiago Quirce, Ignacio Dávila, Julio Delgado, Javier Domínguez-Ortega
BACKGROUND: Spanish population is rather homogeneous in its genetic and socio-cultural characteristics, but allergen sensitization shows wide geographical variations. We aimed at assessing whether sensitization to different allergens in the diverse geographical areas induced different clinical and quality of life characteristics in adult patients with a first-time diagnosis of rhinitis and/or asthma. METHODS: Two sequential, identically designed studies were carried out to evaluate such associations (PERFILAR I and II)...
February 16, 2017: Allergy
https://www.readbyqxmd.com/read/28207004/patch-testing-for-adverse-drug-reactions
#8
Sahil Sekhon, Susan T Nedorost
Adverse drug reactions result in a substantial number of hospital admissions and inpatient events. Diagnosis usually is made with clinical judgment and circumstantiality without diagnostic testing. Furthermore, even in situations where diagnostic testing is performed, no safe gold standard tests exist. Oral rechallenge is currently the gold standard but carries the risk of recrudescence of severe allergic symptoms. Other tests include skin prick tests, the lymphocyte transformation test, immunohistochemistry, and patch testing...
January 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28194756/chlorhexidine-allergy-in-4-specialist-allergy-centres-in-the-uk-2009-2013-clinical-features-and-diagnostic-tests
#9
William Egner, Matthew Helbert, Ravishankar Sargur, Kirsty Swallow, Nigel Harper, Tomaz Garcez, Sinisa Savic, Louise Savic, Eren Effren
We describe an observational survey of diagnostic pathways in 104 patients attending four specialist allergy clinics in the UK following perioperative hypersensitivity reactions to chlorhexidine reactions. The majority were life threatening. Men undergoing urological or cardiothoracic surgery predominated. Skin prick testing and sIgE testing were the most common tests used for diagnosis. Fifty-three % of diagnoses were made on the basis of a single positive test. Where multiple tests were performed the sensitivity of intradermal, basophil activation and skin prick testing was 68% (50-86%), 50% (10-90%) and 35% (17-55%) respectively...
February 14, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28194191/prediction-of-clinical-peanut-allergy-status-among-children-in-hamilton-ontario-using-chart-review-data-collected-during-2012-2015
#10
Elizabeth Simms, Gary Foster, Katherine Arias, Mark Larché, Tosha Freitag, Tina Walker, Susanna Goncharova, Andrea Marrin, Andreas Freitag, Manel Jordana, Susan Waserman
BACKGROUND: Peanut sensitization does not necessarily indicate clinical peanut allergy, and uncertainty as to whether or not there is true peanut allergy can lead to increased anxiety and decreased quality of life for patients and their families. The gold standard for diagnosing clinical peanut allergy is the oral food challenge, but this method is time-consuming and can cause severe allergic reactions. It would therefore be beneficial to develop a tool for predicting clinical peanut allergy in peanut-sensitized individuals whose peanut allergy status is unknown so as to better determine who requires an oral food challenge for diagnosis...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28194190/prevalence-of-allergen-sensitization-in-1000-adults-in-saskatchewan
#11
Stacey D Lok, Beth E Davis, Donald W Cockcroft
BACKGROUND: The prevalence of sensitization varies geographically based on multiple environmental factors including humidity. The aim of this study was to determine the prevalence of atopy in symptomatic adults. More importantly we aimed to obtain a regional statistic of sensitization to common allergens given Saskatchewan's dry climate. METHODS: One thousand consecutive symptomatic adults were screened for atopy via skin prick test over 10 years (2006-2016) in the Division of Respirology...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28188719/-systemic-reaction-after-performing-a-food-prick-to-prick-test-a-case-report
#12
Karen Estefanía Hernández-Moreno, Libia Susana Diez
BACKGROUND: Skin prick test is the most widely used test for the diagnosis of IgE-mediated conditions. Commercial extracts are used for its performance, but in the case of fruits and vegetables it is preferable using fresh food. Although both tests possess a good safety profile, hypersensitivity reactions have been recorded. CLINICAL CASE: Forty-seven-year old woman with a history of persistent allergic rhinitis, sensitized to the pollen of grasses, olive and salsola; she was referred to an allergology department due to anaphylaxis triggered by the consumption of avocado, cantaloupe, carrots and watermelon...
January 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28188708/-skin-reactivity-frequency-to-aeroallergens-in-patients-with-clinical-symptoms-of-allergic-disease
#13
Isabel Cristina Rojas-Méndez, Oswaldo Arana-Muñoz, Aída Inés López-García, Daniela Rivero-Yeverino, Chrystopherson Gengyny Caballero-López, Sergio Papaqui-Tapia, Heriberto Camero-Martínez, Elizabeth Vázquez-Rojas
BACKGROUND: Allergic diseases diagnosis must be based on adequate allergological anamnesis and an immunological sensitization test; the most sensitive and specific is the skin prick test. OBJECTIVE: To determine the frequency of skin reactivity to aeroallergens, by age groups, in patients of the Department of Allergy and Clinical Immunology of the Hospital Universitario de Puebla, in Mexico. METHODS: A cross-sectional study was conducted that included patients aged 2 to 64 years with symptoms suggestive of allergic disease, in which skin prick tests with aeroallergens were performed; the diagnostic criteria were those of international guidelines...
January 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28182031/allergies-in-urban-versus-countryside-settings-in-poland-as-part-of-the-epidemiology-of-the-allergic-diseases-in-poland-ecap-study-challenge-the-early-differential-diagnosis
#14
Edyta Krzych-Fałta, Konrad Furmańczyk, Barbara Piekarska, Aneta Tomaszewska, Adam Sybilski, Bolesław K Samoliński
INTRODUCTION: The incidence of allergies depends on a number of factors, including adopting an urban "western" lifestyle, genetic predispositions, and different regions of residence. AIM: To compare the prevalence of allergic conditions (seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR), bronchial asthma (BA), atopic dermatitis (AD)) in a group of countryside versus urban residents in Poland. MATERIAL AND METHODS: The prevalence of allergic conditions in urban versus countryside settings was assessed using the translated and approved questionnaire developed for international ECRHS II and ISAAC studies...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28177332/a-comparative-study-on-oxidative-stress-role-in-nasal-breathing-impairment-and-obstructive-sleep-apnoea-syndrome
#15
D Passali, G Corallo, A Petti, M Longini, F M Passali, G Buonocore, L M Bellussi
Obstructive sleep apnoea syndrome (OSAS) is a sleep disorder that leads to metabolic abnormalities and increased cardiovascular risk. This study aimed to define the expression and clinical significance of biomarkers involved in oxidative stress in patients with OSAS. A prospective study was designed to compare outcomes of oxidative stress laboratory tests in three groups of subjects. The study involved the recruitment of three groups of subjects, 10 patients with obstructive sleep apnoea syndrome with AHI > 30; 10 patients suffering from snoring at night with AHI < 15; 10 patients with nasal respiratory impairment with AHI < 5...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28174534/behavioral-changes-and-hippocampus-glucose-metabolism-in-app-ps1-transgenic-mice-via-electro-acupuncture-at-governor-vessel-acupoints
#16
Jin Cao, Yinshan Tang, Yujie Li, Kai Gao, Xudong Shi, Zhigang Li
Objective: Investigating the effects of electro-acupuncture (EA) treatment on mice with Alzheimer's disease (AD), using Morris water maze (MWM) for spatial learning and memory behavior tests combined with micro-positron emission tomography (micro-PET) imaging for glucose metabolism in hippocampus. Methods: Thirty seven-month-old APP/PS1 mice were randomly divided into AD Model group (AD group), medicine group (M group) and EA group, C57BL/6 mice were used for Normal control group (N group), n = 10 in each group...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28171712/sensitization-to-common-allergens-among-patients-with-allergy-in-major-iranian-cities-a-systemic-review-and-meta-analysis
#17
Mozhgan Moghtaderi, Saeed Hosseini Teshnizi, Shirin Farjadian
Purpose: Various allergens are implicated in the pathogenesis of allergic diseases in different regions. This study attempted to identify the most common allergens among patients with allergy based on results of skin prick tests in different parts of Iran. Methods: Relevant studies were identified from the Medline database from 2000 to 2016. Six common groups of allergens including animals, cockroaches, foods, fungi, house dust mites and pollen were considered. Subgroup analysis was performed to determine prevalence of each type of allergens...
5, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28169325/aza-heterocyclic-receptors-for-direct-electron-transfer-hemoglobin-biosensor
#18
Vinay Kumar, D M Nikhila Kashyap, Suraj Hebbar, R Swetha, Sujay Prasad, T Kamala, S S Srikanta, P R Krishnaswamy, Navakanta Bhat
Direct Electron Transfer biosensors, facilitating direct communication between the biomolecule of interest and electrode surface, are preferable compared to enzymatic and mediator based sensors. Although hemoglobin (Hb) contains four redox active iron centres, direct detection is not possible due to inaccessibility of iron centres and formation of dimers, blocking electron transfer. Through the coordination of iron with aza-heterocyclic receptors - pyridine and imidazole - we report a cost effective, highly sensitive and simple electrochemical Hb sensor using cyclic voltammetry and chronoamperometry...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28166066/prevalence-of-sensory-neuropathy-in-type-2-diabetes-mellitus-and-its-correlation-with-duration-of-disease
#19
D B Karki, S K Yadava, S Pant, N Thusa, E Dangol, S Ghimire
Background Peripheral neuropathy is one of the most common and distressing late complication of diabetes mellitus. Ignorance of the complications may develop foot ulcers and gangrene requiring amputation. Objective The main objective of this study is to find out the prevalence of sensory neuropathy in type 2 diabetes mellitus and to compare it with the duration of disease. Method Two hundred seventy one patients with type 2 diabetes mellitus of both gender age 30 years and above willing to participate were included in this study...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28164808/emerging-food-allergens-identification-of-polyphenol-oxidase-as-an-important-allergen-in-eggplant-solanum-melongena-l
#20
Bheemanapalli N Harish Babu, Anthony Wilfred, Yeldur P Venkatesh
Although many allergens have been detected in eggplant (Solanum melongena L.), their identity have not been elucidated. The aim of this study was to investigate whether polyphenol oxidase (PPO), an important eggplant enzyme, acts as an allergen. The proteins of eggplant peel extract were separated on phenyl-Sepharose (PS), and analyzed by skin prick test (SPT), ELISA and IgE-immunoblotting; the components were analyzed for PPO activity, presence of protein-bound copper, and recognition by rabbit polyclonal anti-sweet potato PPO antiserum...
February 2017: Immunobiology
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