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https://www.readbyqxmd.com/read/29678409/phototherapy-for-neonatal-hyperbilirubinemia-and-childhood-eczema-rhinitis-and-wheeze
#1
Elizabeth Huiwen Tham, Evelyn Xiu Ling Loo, Anne Goh, Oon Hoe Teoh, Fabian Yap, Kok Hian Tan, Keith M Godfrey, Hugo Van Bever, Bee Wah Lee, Yap Seng Chong, Lynette Pei-Chi Shek
BACKGROUND: The pathogenesis of allergic diseases in childhood may be attributed to influences of early environmental stimuli on fetal and neonatal immune regulation. Neonatal hyperbilirubinemia is common in the Asian population and up to 20% of infants require phototherapy. We examined the hypothesis that phototherapy for neonatal hyperbilirubinemia modulates the infant's risk of developing eczema, rhinitis and wheeze in the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort...
March 24, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29674239/relationship-between-domestic-smoking-and-metals-and-rare-earth-elements-concentration-in-indoor-pm-2-5
#2
Gaspare Drago, Cinzia Perrino, Silvia Canepari, Silvia Ruggieri, Luca L'Abbate, Valeria Longo, Paolo Colombo, Daniele Frasca, Martin Balzan, Giuseppina Cuttitta, Gianluca Scaccianoce, Giuseppe Piva, Salvatore Bucchieri, Mario Melis, Giovanni Viegi, Fabio Cibella, Martin Balzan, David Bilocca, Charles Borg, Stephen Montefort, Christopher Zammit, Salvatore Bucchieri, Fabio Cibella, Paolo Colombo, Giuseppina Cuttitta, Gaspare Drago, Giuliana Ferrante, Luca L'Abbate, Stefania La Grutta, Valeria Longo, Mario R Melis, Silvia Ruggieri, Giovanni Viegi, Remo Minardi, Giuseppe Piva, Rosaria Ristagno, Gianfranco Rizzo, Gianluca Scaccianoce
Cigarette smoke is the main source of indoor chemical and toxic elements. Cadmium (Cd), Thallium (Tl), Lead (Pb) and Antimony (Sb) are important contributors to smoke-related health risks. Data on the association between Rare Earth Elements (REE) Cerium (Ce) and Lanthanum (La) and domestic smoking are scanty. To evaluate the relationship between cigarette smoke, indoor levels of PM2.5 and heavy metals, 73 children were investigated by parental questionnaire and skin prick tests. The houses of residence of 41 "cases" and 32 "controls" (children with and without respiratory symptoms, respectively) were evaluated by 48-h PM2...
April 16, 2018: Environmental Research
https://www.readbyqxmd.com/read/29666610/fungi-induced-upper-and-lower-respiratory-tract-allergic-diseases-one-entity
#3
Aleksandra Barac, David S Y Ong, Ljiljana Jovancevic, Aleksandar Peric, Pavol Surda, Vesna Tomic Spiric, Salvatore Rubino
Introduction: Aspergillus can cause different allergic diseases including allergic bronchopulmonary aspergillosis (ABPA) and allergic fungal rhinosinusitis (AFRS). ABPA is allergic pulmonary disease against Aspergillus antigens. AFRS is a type of chronic rhinosinusitis (CRS) presented as hypersensitivity reactions to the fungal presence in sinuses. The aim of the present study was to clarify if ABPA and AFRS could be considered as a common disease entity. Methodology: The prospective cohort study included 75 patients with ABPA...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29666553/the-potential-of-component-resolved-diagnosis-in-laboratory-diagnostics-of-allergy
#4
REVIEW
Slavica Dodig, Ivana Čepelak
The initial laboratory approach in the diagnosis of allergies is to detect the type of allergic reaction, i.e. whether the patient's allergy is mediated by immunoglobulin E (IgE) or not. For this purpose, the concentration of total serum IgE (tIgE) and specific IgE (sIgE) are determined. Progress in laboratory diagnostics is the use of component-resolved diagnosis (CRD) which implies determination of sIgE against purified native and recombinant allergenic molecules. Component-resolved diagnosis is used in laboratory practice as singleplex and multiplex assays...
June 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29661061/correlation-of-nasal-eosinophilia-and-response-after-nasal-provocation-test-in-patients-with-nonallergic-rhinitis
#5
Ki-Ik Park, Tae Young Jang, Seung-Chan Yang, Hyung Sun Hong, Young Hyo Kim
Objectives We aimed to evaluate the relationship between nasal eosinophilia and nasal hyperresponsiveness to allergen extract. Study Design Retrospective chart review. Setting Academic tertiary rhinologic practice. Subjects and Methods We performed allergy tests (skin prick test and multiple allergosorbent test) and nasal cytology for 194 patients with rhinitis symptoms (76 males and 118 females; age, 11-69 years). According to the results, they were classified into 4 groups: group A (allergic rhinitis with eosinophilia, n = 26), group B (allergic rhinitis without eosinophilia, n = 77), group C (nonallergic rhinitis with eosinophilia syndrome, n = 20), and group D (nonallergic rhinitis without eosinophilia, n = 71)...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29660855/the-impact-of-oral-food-challenges-for-food-allergy-on-quality-of-life-a-systematic-review
#6
Hannah M Kansen, Thuy-My Le, Yolanda Meijer, Bertine M J Flokstra-de Blok, Paco M J Welsing, Cornelis K van der Ent, André C Knulst, Francine C van Erp
BACKGROUND: Food allergy significantly impairs health-related quality of life (HRQL). Currently, it is still unknown whether diagnostic interventions for food allergy improve HRQL. We aim to assess the impact of diagnostic interventions for food allergy on HRQL. METHODS: A systematic search was performed in MEDLINE, Embase, Cochrane Library and CINAHL focused on patients with a (suspected) food allergy who underwent diagnostic interventions (i.e. skin prick test, specific IgE or oral food challenges (OFC)), and in whom HRQL was assessed...
April 16, 2018: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29660251/the-association-of-nasal-patency-with-small-airway-resistance-in-children-with-allergic-and-nonallergic-rhinitis
#7
Joo Young Song, Eun Kyo Ha, Yoon Ho Sheen, Mi-Ae Kim, Seung Won Lee, Jung Won Yoon, Seung Jin Lee, Young-Ho Jung, Kyung Suk Lee, Jae-Cheul Ahn, Hye Mi Jee, Man Yong Han
INTRODUCTION: Allergic rhinitis (AR) is immunologically and morphologically related to disorders in the lower airway. We investigated the relationship between the anatomy of the intranasal cavity and small airway resistance in subjects with nonallergic rhinitis (NAR). METHODS: We enrolled 226 children who were 7 years old and participated in the Seongnam Atopy Project 2016. We evaluated nasal patency using acoustic rhinometry to measure the volume of the nasal cavity at 0 to 5 cm, and measured lung function of the lower airway using an impulse oscillometry system (IOS) and spirometry...
April 16, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29656669/the-effect-of-the-facilitated-tucking-position-on-pain-intensity-during-heel-stick-blood-sampling-in-premature-infants-a-surprising-result
#8
Samaneh Davari, Leili Borimnejad, Sharareh Khosravi, Hamid Haghani
BACKGROUND: According to research findings, pain experience in neonatal period leads to short and long term complications that could be prevented by means of neonatal pain relief. Therefore, this study aimed to investigate the effect of facilitated tucking position on neonatal pain during heel prick blood sampling. METHODS: This is a cross over clinical trial was done on 40 premature neonates. During blood sampling neonates were put in either facilitated tucking or routine positions randomly and Premature Infant Pain Profile (PIPP) was completed for each neonate...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29642932/early-life-swimming-pool-exposure-and-asthma-onset-in-children-a-case-control-study
#9
Martin Andersson, Helena Backman, Gunnar Nordberg, Annika Hagenbjörk, Linnea Hedman, Kåre Eriksson, Bertil Forsberg, Eva Rönmark
BACKGROUND: Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. METHODS: A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16-17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews...
April 11, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29621308/acceptability-and-performance-of-a-directly-assisted-oral-hiv-self-testing-intervention-in-adolescents-in-rural-mozambique
#10
Jonas Hector, Mary-Ann Davies, Johanna Dekker-Boersema, Mussa Manuel Aly, Cassimo Charifo A Abdalad, Ernesto Belario Rafael Langa, Jochen Ehmer, Michael Andre Hobbins, Laura Frances Jefferys
INTRODUCTION: Whereas progress in HIV testing and treatment has been made globally, the UNAIDS goal of "90 90 90" is still out of sight in rural northern Mozambique. New strategies that promote testing in hard to reach groups will aid Mozambique's response to the HIV epidemic. HIV self-testing (HIVST) is recommended by the WHO as an additional approach to augment the HIV testing services available to adolescents. This study evaluates acceptability and performance of a directly assisted oral HIVST intervention for adolescents in rural Mozambique...
2018: PloS One
https://www.readbyqxmd.com/read/29607408/therapeutic-effects-of-prolonged-cannabidiol-treatment-on-psychological-symptoms-and-cognitive-function-in-regular-cannabis-users-a-pragmatic-open-label-clinical-trial
#11
Nadia Solowij, Samantha J Broyd, Camilla Beale, Julie-Anne Prick, Lisa-Marie Greenwood, Hendrika van Hell, Chao Suo, Peter Galettis, Nagesh Pai, Shanlin Fu, Rodney J Croft, Jennifer H Martin, Murat Yücel
Introduction: Chronic cannabis use has been associated with impaired cognition and elevated psychological symptoms, particularly psychotic-like experiences. While Δ9 -tetrahydrocannabinol (THC) is thought to be primarily responsible for these deleterious effects, cannabidiol (CBD) is purported to have antipsychotic properties and to ameliorate cognitive, symptomatic, and brain harms in cannabis users. However, this has never been tested in a prolonged administration trial in otherwise healthy cannabis users...
2018: Cannabis and Cannabinoid Research
https://www.readbyqxmd.com/read/29605362/can-the-number-of-eosinophils-in-adenoid-and-tonsil-tissue-determine-the-allergy-in-children
#12
Nur Yucel Ekici, Orhan Görgülü, Gül Yucel, Özgür Külahcı, Osman Kürşat Arıkan, Cemile Durmaz
OBJECTIVE: Previous reports have indicated the association of allergy with Waldeyer's ring. The aim of this prospective study was to evaluate the correlation between the allergy and the number of eosinophils in the adenoid and tonsil tissue. METHODS: 101 children who were underwent adenoidectomy and/or tonsillectomy were prospectively enrolled in this study. 46 children who had positive skin-prick test for at least one of the allergen panel were sensitized and 55 children were nonsensitized as a result of skin-prick test...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29601353/how-to-diagnose-food-allergy
#13
Sakura Sato, Noriyuki Yanagida, Motohiro Ebisawa
PURPOSE OF REVIEW: To assess the recent studies that focus on specific immunoglobulin E (sIgE) testing and basophil activation test (BAT) for diagnosing IgE-mediated food allergies. RECENT FINDINGS: The sIgE to allergen extract or component can predict reactivity to food. The cutoff value based on the positive predictive value (PPV) of sIgE can be considered whenever deciding whether oral food challenge (OFC) is required to diagnose hen's egg, cow's milk, wheat, peanut, and cashew nut allergy...
March 29, 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29599676/cross-sensitization-to-artemisia-and-ambrosia-pollen-allergens-in-an-area-located-outside-of-the-current-distribution-range-of-ambrosia
#14
Łukasz Grewling, Dorota Jenerowicz, Paweł Bogawski, Matt Smith, Małgorzata Nowak, Agata Frątczak, Magdalena Czarnecka-Operacz
Introduction: The role of long-distance transported (LDT) Ambrosia pollen in inducing new sensitization and affecting sensitization rates in Artemisia -sensitized patients is unclear. Aim: The aim of this study was to estimate the degree of cross-sensitization to Ambrosia/Artemisi a allergens in citizens of Poznan (Western Poland). This area is covered by extensive Artemisia populations but does not currently have local Ambrosia populations. Material and methods: Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of Artemisia vulgaris and Ambrosia artemisiifolia , an allergenic component of A...
February 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29590653/misleading-allergens-in-the-diagnosis-of-latex-allergy-profilin-and-cross-reactive-carbohydrate-determinants
#15
Feridun Gürlek, Mehmet Ünsel, Ömür Ardeniz, Zeynep Peker Koc, Okan Gülbahar, Aytül Zerrin Sin, Ali Kokuludag, Nihal Mete Gokmen
BACKGROUND: It has been suggested that latex-specific IgE analysis may lead to false-positive results, especially in patients with pollen allergy. In the present study, the reasons underlying clinically irrelevant latex-specific IgE positivity were investigated. METHODS: Thirty patients with latex allergy (group 1), 89 patients sensitised to aeroallergens (group 2a), and 98 healthy individuals without allergy (group 2b) were enrolled. Participants from all 3 groups were subjected to skin prick tests with aeroallergens including latex, latex-specific IgE analysis (ImmunoCAP), and nasal provocation test with latex...
March 28, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29588830/allergic-bronchopulmonary-aspergillosis-in-patients-with-cystic-fibrosis-and-non-cystic-fibrosis-bronchiectasis
#16
Soheila Alyasin, Mozhgan Moghtaderi, Shirin Farjadian, Maryam Babaei, Saeed Hosseini Teshnizi
Background: Aspergillus sensitization (AS) and allergic bronchopulmonary aspergillosis (ABPA) can occur as a cause of permanent lung damage in patients with cystic fibrosis (CF) and non-CF bronchiectasis. Objective: The aim of this study was to determine the frequency of AS and ABPA in patients with CF and non-CF bronchiectasis in southwestern Iran. Methods: This cross-sectional study was conducted on 33 patients with CF and 27 patients with non-CF bronchiectasis from southwestern Iran who were referred to Namazi Hospital affiliated to Shiraz University of Medical Sciences from July 2015 to February 2016...
January 2018: Electronic Physician
https://www.readbyqxmd.com/read/29587831/childhood-fish-oil-supplementation-modifies-associations-between-traffic-related-air-pollution-and-allergic-sensitisation
#17
Anna L Hansell, Ioannis Bakolis, Christine T Cowie, Elena G Belousova, Kitty Ng, Christina Weber-Chrysochoou, Warwick J Britton, Stephen R Leeder, Euan R Tovey, Karen L Webb, Brett G Toelle, Guy B Marks
BACKGROUND: Studies of potential adverse effects of traffic related air pollution (TRAP) on allergic disease have had mixed findings. Nutritional studies to examine whether fish oil supplementation may protect against development of allergic disease through their anti-inflammatory actions have also had mixed findings. Extremely few studies to date have considered whether air pollution and dietary factors such as fish oil intake may interact, which was the rationale for this study. METHODS: We conducted a secondary analysis of the Childhood Asthma Prevention Study (CAPS) birth cohort, where children were randomised to fish oil supplementation or placebo from early life to age 5 years...
March 27, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29573248/comparison-between-newly-developed-and-commercial-inhalant-skin-prick-test-reagents-using-in-vivo-and-in-vitro-methods
#18
Sang Chul Lee, Da Woon Sim, Jongsun Lee, Kyoung Yong Jeong, Kyung Hee Park, Jae Hyun Lee, Jung Dong Kim, Jung Won Park
BACKGROUND: We developed skin prick test (SPT) reagents for common inhalant allergens that reflected the real exposure in Korea. The study aim was to evaluate diagnostic usefulness and allergen potency of our inhalant SPT reagents in comparison with commercial products. METHODS: We produced eight common inhalant allergen SPT reagents using total extract (Prolagen): Dermatophagoides farinae, Dermatophagoides pteronyssinus, oak, ragweed, mugwort, Humulus japonicus pollens, as well as cat and dog allergens...
March 26, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29568547/hiv-rapid-diagnostic-testing-by-lay-providers-in-a-key-population-led-health-service-programme-in-thailand
#19
EDITORIAL
Rapeeporn Wongkanya, Tippawan Pankam, Shauna Wolf, Supanit Pattanachaiwit, Jureeporn Jantarapakde, Supabhorn Pengnongyang, Prasopsuk Thapwong, Apichat Udomjirasirichot, Yutthana Churattanakraisri, Nanthika Prawepray, Apiluk Paksornsit, Thidadaow Sitthipau, Sarayut Petchaithong, Raruay Jitsakulchaidejt, Somboon Nookhai, Cheewanan Lertpiriyasuwat, Sumet Ongwandee, Praphan Phanuphak, Nittaya Phanuphak
Introduction:  Rapid diagnostic testing (RDT) for HIV has a quick turn-around time, which increases the proportion of people testing who receive their result. HIV RDT in Thailand has traditionally been performed only by medical technologists (MTs), which is a barrier to its being scaled up. We evaluated the performance of HIV RDT conducted by trained lay providers who were members of, or worked closely with, a group of men who have sex with men (MSM) and with transgender women (TG) communities, and compared it to tests conducted by MTs...
January 1, 2018: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29566971/the-mega-project-a-study-of-the-mechanisms-involved-in-the-genesis-and-disease-course-of-asthma-asthma-cohort-creation-and-long-term-follow-up
#20
Xavier Muñoz, María José Álvarez-Puebla, Ebymar Arismendi, Lourdes Arochena, María Del Pilar Ausín, Pilar Barranco, Irina Bobolea, Jose Antonio Cañas, Blanca Cardaba, Astrid Crespo, Victora Del Pozo, Javier Domínguez-Ortega, María Del Mar Fernandez-Nieto, Jordi Giner, Francisco Javier González-Barcala, Juan Alberto Luna, Joaquim Mullol, Iñigo Ojanguren, José María Olaguibel, César Picado, Vicente Plaza, Santiago Quirce, David Ramos, Manuel Rial, Christian Romero-Mesones, Francisco Javier Salgado, María Esther San-José, Silvia Sánchez-Diez, Beatriz Sastre, Joaquin Sastre, Lorena Soto, Montserrat Torrejón, Marisa Urnadoz, Luis Valdes, Antonio Valero, María Jesús Cruz
The general aim of this study is to create a cohort of asthma patients with varying grades of severity in order to gain greater insight into the mechanisms underlying the genesis and course of this disease. The specific objectives focus on various studies, including imaging, lung function, inflammation, and bronchial hyperresponsiveness, to determine the relevant events that characterize the asthma population, the long-term parameters that can determine changes in the severity of patients, and the treatments that influence disease progression...
March 19, 2018: Archivos de Bronconeumología
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