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https://www.readbyqxmd.com/read/29571030/prediction-of-new-onset-atrial-fibrillation-after-first-ever-ischemic-stroke-a-comparison-of-chads-2-cha-2-ds-2-vasc-and-hatch-scores-and-the-added-value-of-stroke-severity
#1
Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung
BACKGROUND AND AIMS: Early detection of atrial fibrillation after stroke is important for secondary prevention in stroke patients without known atrial fibrillation (AF). We aimed to compare the performance of CHADS2 , CHA2 DS2 -VASc and HATCH scores in predicting AF detected after stroke (AFDAS) and to test whether adding stroke severity to the risk scores improves predictive performance. METHODS: Adult patients with first ischemic stroke event but without a prior history of AF were retrieved from a nationwide population-based database...
March 15, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29483010/modified-chads-2-and-cha-2-ds-2-vasc-scores-to-predict-atrial-fibrillation-in-acute-ischemic-stroke-patients
#2
Rixia Liu, Xiaomeng Yang, Shuya Li, Yong Jiang, Yilong Wang, Yongjun Wang
It is important to identify candidates who warrant extended cardiac monitoring after ischemic stroke. We investigated the predictive performance of the CHADS2 and CHA2 DS2 -VASc scores for previously unknown atrial fibrillation during in-hospital electrocardiographic monitoring. Patients were selected from a prospective trial in China. The clinical prediction of the scores was examined using the C statistic. Multivariate logistic regressions were performed to analyze the relevant risk factors. Among 1315 patients enrolled in study, previously unknown atrial fibrillation was detected in 110 (8...
February 23, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29374047/use-of-direct-oral-anticoagulants-in-canadian-primary-care-practice-2010-2015-a-cohort-study-from-the-canadian-primary-care-sentinel-surveillance-network
#3
Finlay A McAlister, Scott Garrison, Leanne Kosowan, Justin A Ezekowitz, Alexander Singer
BACKGROUND: As questions have been raised about the appropriateness of direct oral anticoagulant (DOAC) dosing among outpatients with atrial fibrillation, we examined this issue in patients being managed by primary care providers. METHODS AND RESULTS: This was a retrospective cohort new-user study using electronic medical records from 744 Canadian primary care clinicians. Potentially inappropriate DOAC prescribing was defined as prescribing lower or higher doses than those recommended by guidelines for patients with nonvalvular atrial fibrillation...
January 26, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29235900/treatment-and-discharge-patterns-among-patients-hospitalized-with-non-valvular-atrial-fibrillation-transitioning-from-the-inpatient-to-outpatient-setting
#4
Henry J Henk, Feng Cao, Kenneth Tuell, Kwanza Price, Prianka Singh, Jack Mardekian, Kevin Odell, Chad Patel, Wilson Tan, George H Sands, Shalabh Singhal, Jeffrey Trocio, Lien Vo
OBJECTIVE: To evaluate inpatient oral anticoagulant (OAC) treatment, discharge location, and post-discharge OAC treatment for patients hospitalized with non-valvular atrial fibrillation (NVAF). RESEARCH DESIGN AND METHODS: Retrospective study using claims data linked to hospital electronic health records (EHR). Patients (n = 2,484) were hospitalized with a primary (38%) or secondary (62%) diagnosis of AF without evidence of mitral valvular heart disease or valve replacement between January 2009 and September 2013...
March 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28851729/assessment-of-remote-heart-rhythm-sampling-using-the-alivecor-heart-monitor-to-screen-for-atrial-fibrillation-the-rehearse-af-study
#5
RANDOMIZED CONTROLLED TRIAL
Julian P J Halcox, Kathie Wareham, Antonia Cardew, Mark Gilmore, James P Barry, Ceri Phillips, Michael B Gravenor
BACKGROUND: Asymptomatic atrial fibrillation (AF) is increasingly common in the aging population and implicated in many ischemic strokes. Earlier identification of AF with appropriate anticoagulation may decrease stroke morbidity and mortality. METHODS: We conducted a randomized controlled trial of AF screening using an AliveCor Kardia monitor attached to a WiFi-enabled iPod to obtain ECGs (iECGs) in ambulatory patients. Patients ≥65 years of age with a CHADS-VASc score ≥2 free from AF were randomized to the iECG arm or routine care (RC)...
November 7, 2017: Circulation
https://www.readbyqxmd.com/read/28070875/atrial-fibrillation-inducibility-during-cavotricuspid-isthmus-dependent-atrial-flutter-ablation-as-a-predictor-of-clinical-atrial-fibrillation-a-meta-analysis
#6
REVIEW
Jorge Romero, Juan Carlos Diaz, Luigi Di Biase, Saurabh Kumar, David Briceno, Usha B Tedrow, Carolina R Valencia, Samuel H Baldinger, Bruce Koplan, Laurence M Epstein, Roy John, Gregory F Michaud, William G Stevenson
BACKGROUND: Atrial fibrillation (AF) and cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL) are two separate entities that coexist in a significant percentage of patients. We sought to investigate whether AF inducibility during CTI AFL ablation predicted the occurrence of AF at follow-up after successful AFL ablation. METHODS: A systemic review of Medline, Cochrane, and Embase was done for all the clinical studies in which assessment of AF inducibility in patients undergoing ablation for CTI AFL was performed...
April 2017: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/28068791/the-utilization-of-antithrombotic-therapy-in-older-patients-in-aged-care-facilities-with-atrial-fibrillation
#7
Bridget Frain, Ronald Castelino, Luke R Bereznicki
Oral anticoagulants are essential drugs for the prevention of thromboembolic events in patients with atrial fibrillation (AF). Anticoagulants are, however, commonly withheld in older people due to the risk and fear of hemorrhage. Although the underutilization of anticoagulants in patients with AF has been demonstrated internationally, few studies have been conducted among aged care residents. The aim of this study was to determine the utilization of anticoagulants among people with AF residing in aged care facilities...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/27754141/os-27-05-frailty-assessment-in-older-atrial-fibrillation-patients
#8
Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Min-Gu Kang, Kwang-Il Kim, Cheol-Ho Kim
OBJECTIVE: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to balance the benefit against the risk of bleeding...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643071/os-27-05-frailty-assessment-in-older-atrial-fibrillation-patients
#9
Sun-Wook Kim, Sol-Ji Yoon, Jung-Yeon Choi, Min-Gu Kang, Kwang-Il Kim, Cheol-Ho Kim
OBJECTIVE: Atrial fibrillation is the common arrhythmia in the elderly, and the average age of atrial fibrillation patients is rising. Elderly patients with atrial fibrillation have high incidence of thromboembolic complication and increasing age is associated with stroke severity. Assessing CHADS-VASc score is pivotal to evaluate substantial morbidity and mortality, especially regarding the increased risk of stroke. In addition, considering bleeding risk with HAS-BLED score is important to balance the benefit against the risk of bleeding...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27447814/valvular-chads-vasc-as-a-safer-alternative-to-chads-vasc-score
#10
LETTER
Victoria Chatzimavridou-Grigoriadou, Prodromos Kanavidis, Alexander G Mathioudakis
No abstract text is available yet for this article.
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27027899/left-atrial-geometry-improves-risk-prediction-of-thromboembolic-events-in-patients-with-atrial-fibrillation
#11
MULTICENTER STUDY
Felipe Bisbal, Federico Gómez-Pulido, Pilar Cabanas-Grandío, Nazem Akoum, Mireia Calvo, David Andreu, Susanna Prat-González, Rosario J Perea, Roger Villuendas, Antonio Berruezo, Marta Sitges, Antoni Bayés-Genís, Josep Brugada, Nassir F Marrouche, Lluís Mont
BACKGROUND: Left atrial (LA) sphericity (LASP) is a new remodeling parameter based on LA shape analysis, with independent predictive value for recurrence after atrial fibrillation (AF) ablation. OBJECTIVES: To evaluate the association between LASP and thromboembolic events (TE) in patients with AF. METHODS: Twenty-nine AF patients and prior TE and 29 age- and gender-matched controls were included. LASP was calculated using a 3D-LA reconstruction...
July 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/26467380/inappropriate-combination-of-warfarin-and-aspirin
#12
Burak Turan, Hakan Demir, Ayhan Mutlu, Tolga Daşlı, Ayhan Erkol, İsmail Erden
OBJECTIVE: A combination of warfarin and aspirin is associated with increased bleeding compared with warfarin monotherapy. The aim of the study was to investigate the incidence and appropriateness of the combination of warfarin and aspirin in patients with atrial fibrillation (AF) or mechanical heart valve (MHV). METHODS: This cross-sectional study included consecutive patients with AF or MHV on chronic warfarin therapy (>3 months) without acute coronary syndrome or have not undergone a revascularization procedure in the preceding year...
March 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/25851318/cardiac-ct-angiography-for-device-surveillance-after-endovascular-left-atrial-appendage-closure
#13
Jacqueline Saw, Peter Fahmy, Peggy DeJong, Mathieu Lempereur, Ryan Spencer, Michael Tsang, Kenneth Gin, John Jue, John Mayo, Patrick McLaughlin, Savvas Nicolaou
AIMS: Left atrial appendage (LAA) device imaging after endovascular closure is important to assess for device thrombus, residual leak, positioning, surrounding structures, and pericardial effusion. Cardiac CT angiography (CCTA) is well suited to assess these non-invasively. METHODS AND RESULTS: We report our consecutive series of non-valvular atrial fibrillation patients who underwent CCTA post-LAA closure with Amplatzer Cardiac Plug (ACP), Amulet (second generation ACP), or WATCHMAN devices...
November 2015: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/25733318/can-thromboembolic-risk-be-associated-with-erectile-dysfunction-in-atrial-fibrillation-patients
#14
Filip M Szymański, Krzysztof J Filipiak, Anna E Płatek, Marcin Kotkowski, Grzegorz Opolski
BACKGROUND: Erectile dysfunction (ED) is highly prevalent in patients with diseases of cardiovascular system, including patients with atrial fibrillation (AF). Reasons for this high co-prevalence include endothelial dysfunction, inflammation, oxidative and emotional stress associated with AF. Association of AF-induced prothrombotic state and possible microthrombi in penile arteries with ED remains unclear. The present study aims to assess if probability of AF-associated risk of peripheral thromboembolism may be associated with ED in AF patients...
2015: Cardiology Journal
https://www.readbyqxmd.com/read/25683989/factors-associated-with-ischemic-stroke-on-therapeutic-anticoagulation-in-patients-with-nonvalvular-atrial-fibrillation
#15
MULTICENTER STUDY
Young Dae Kim, Kyung Yul Lee, Hyo Suk Nam, Sang Won Han, Jong Yun Lee, Han-Jin Cho, Gyu Sik Kim, Seo Hyun Kim, Myoung-Jin Cha, Seong Hwan Ahn, Seung-Hun Oh, Kee Ook Lee, Yo Han Jung, Hye-Yeon Choi, Sang-Don Han, Hye Sun Lee, Chung Mo Nam, Eun Hye Kim, Ki Jeong Lee, Dongbeom Song, Hui-Nam Park, Ji Hoe Heo
PURPOSE: In this study, we investigated the stroke mechanism and the factors associated with ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF) who were on optimal oral anticoagulation with warfarin. MATERIALS AND METHODS: This was a multicenter case-control study. The cases were consecutive patients with NVAF who developed cerebral infarction or transient ischemic attack (TIA) while on warfarin therapy with an international normalized ratio (INR) ≥2 between January 2007 and December 2011...
March 2015: Yonsei Medical Journal
https://www.readbyqxmd.com/read/24922917/14%C3%A2-are-patients-with-stroke-and-atrial-fibrillation-receiving-appropriate-anticoagulation
#16
Cho Thae Phyu, Caroline Taylor, Zainab Khan, Richard Cowell
AIM: To improve an appropriate use of antithrombotic therapy in atrial fibrillation (AF) on the basis of the presence (or absence) of stroke risk factors (based on CHA2DS2VASc score) as per ESC guideline. METHOD: This was a retrospective audit and data was obtained from the health record department on the total number of stroke admissions in 2012. A proforma based on the ECS guide was created and used to collect data from those that were coded as having a diagnosis of AF alongside the CVA...
June 2014: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/24846512/roles-of-the-chads2-and-cha2ds2-vasc-scores-in-post-myocardial-infarction-patients-risk-of-new-occurrence-of-atrial-fibrillation-and-ischemic-stroke
#17
Kui-Kai Lau, Pak-Hei Chan, Kai-Hang Yiu, Yap-Hang Chan, Shasha Liu, Koon-Ho Chan, Chun-Yip Yeung, Sheung-Wai Li, Hung-Fat Tse, Chung-Wah Siu
BACKGROUND: Patients with myocardial infarction (MI) are at risk of the development of atrial fibrillation (AF) and ischemic stroke. We sought to evaluate the prognostic performance of the CHADS₂ and CHA₂DS₂-VASc scores in predicting new AF and/or ischemic stroke in post-ST segment elevation MI (STEMI) patients. Six hundred and seven consecutive post-STEMI patients with no previously documented AF were studied. METHODS AND RESULTS: After a follow-up of 63 months (3,184 patient-years), 83 (13...
2014: Cardiology Journal
https://www.readbyqxmd.com/read/24252289/additive-effect-of-the-metabolic-syndrome-score-to-the-conventional-chads%C3%A2-score-for-the-thromboembolic-risk-stratification-of-patients-with-atrial-fibrillation
#18
Chia-Ti Tsai, Shu-Hsuan Chang, Sheng-Nan Chang, Juey-Jen Hwang, Cho-Kai Wu, Yi-Chih Wang, Chuen-Den Tseng, Huei-Ming Yeh, Ling-Ping Lai, Fu-Tien Chiang, Jiunn-Lee Lin
BACKGROUND: The CHA₂DS₂-VASC scoring scheme may not be better than the CHADS₂ scoring scheme in predicting thromboembolic risk for patients with atrial fibrillation (AF) in Asians. Metabolic syndrome is associated with an increased risk of thrombosis. OBJECTIVE: To evaluate whether metabolic syndrome offers incremental information over the CHADS₂ scheme in predicting thromboembolic risk for patients with AF in the Taiwanese population. METHODS: The study population consisted of 721 consecutive patients with AF who had been followed up for a median of 10...
March 2014: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/24157563/antithrombotic-therapy-in-transient-ischemic-attack-patients
#19
REVIEW
V E Held, M E Wolf, M G Hennerici
Historically, studies of antithrombotic therapy in ischemic cerebrovascular disease have included both stroke and transient ischemic attack (TIA). Thus, therapy regimes are very similar. Aspirin (75-325 mg within 48 h after onset of symptoms) is still the standard antithrombotic treatment because other agents have performed similarly (or worse). Combinations of agents have shown mixed results. Aspirin combined with clopidogrel has failed to show a significant reduction of stroke/TIA recurrences but increased the bleeding risk if taken for more than several months...
2014: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/23990227/anticoagulant-and-antiplatelet-therapy-for-stroke-prevention-in-atrial-fibrillation-patients-in-the-clinical-practice-of-a-single-district-hospital-in-poland
#20
Janusz Bednarski, Ewa Cieszewska, Aleksander Strzelecki, Krzysztof J Filipiak
BACKGROUND AND AIM: Retrospective evaluation of stroke risk in all patients with atrial fibrillation (AF) admitted to cardiology, internal medicine, and neurology wards in a single Polish district hospital in 2006 and 2010 using two risk stratification schemes, CHADS₂ vs. CHA₂DS₂VASc risk scores and identification of independent predictors of guideline-compliant oral anticoagulant (OAC) treatment. METHODS: We analysed case records of 613 patients with AF (including 300 patients in 2006 and 313 patients in 2010) treated in a district hospital - the John Paul II Western Hospital (Szpital Zachodni) in Grodzisk Mazowiecki, to evaluate their stroke risk and therapy prescribed at discharge...
2013: Kardiologia Polska
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