keyword
https://read.qxmd.com/read/38503407/predictive-validity-of-a-pressure-injury-risk-assessment-tool-at-different-time-points-in-patients-admitted-to-the-intensive-care-unit
#21
JOURNAL ARTICLE
Angel Cobos-Vargas, Maria Acosta-Romero, Luis Camado-Sojo, Carmen Alba-Fernández, Esther Rodriguez-Delgado, Manuel Colmenero
BACKGROUND: Multiple risk assessment scales are available for predicting the development of pressure injuries (PIs) in patients in the intensive care unit (ICU). Most PI risk assessment tools have been validated at the time of admission; however, another time point during treatment could better reflect clinical changes and therefore, the risk of PIs. AIMS: The study aimed to examine the predictive validity of PI risk assessment scale designed for ICU patients, the conscious level, mobility, haemodynamic, oxygenation and nutrition (COMHON) index, at several time points or intervals during ICU stay...
March 19, 2024: Nursing in Critical Care
https://read.qxmd.com/read/38497892/tocilizumab-treatment-in-covid-19-patients-therapy-s-side-effects-and-effect-on-mortality
#22
JOURNAL ARTICLE
P Ayvat, S Kayhan Omeroglu
OBJECTIVE: This study aimed to determine the effect of tocilizumab use on mortality and the potential side effects in COVID-19 patients. PATIENTS AND METHODS: The intensive care patients were divided into the tocilizumab group and the control group. Hemogram, biochemistry, acute phase reactant values, age, gender, comorbidity, and culture results were recorded on the 0th, 3rd, 7th, and 14th days. Factors affecting mortality between and within the groups and side effects were examined...
March 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38497568/protracted-fibrinolysis-resistance-following-cardiac-surgery-with-cardiopulmonary-bypass-a-prospective-observational-study-of-clinical-associations-and-patient-outcomes
#23
JOURNAL ARTICLE
Lucy A Coupland, Kieran G Pai, Sidney J Pye, Mark T Butorac, Jennene J Miller, Philip J Crispin, David J Rabbolini, Antony H L Stewart, Anders Aneman
BACKGROUND: Surgery on cardiopulmonary bypass (CPB) elicits a pleiomorphic systemic host response which, when severe, requires prolonged intensive care support. Given the substantial cross-talk between inflammation, coagulation, and fibrinolysis, the aim of this hypothesis-generating observational study was to document the kinetics of fibrinolysis recovery post-CPB using ClotPro® point-of-care viscoelastometry. Tissue plasminogen activator-induced clot lysis time (TPA LT, s) was correlated with surgical risk, disease severity, organ dysfunction and intensive care length of stay (ICU LOS)...
March 18, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38489557/machine-learning-based-peri-surgical-risk-calculator-for-abdominal-related-emergency-general-surgery-a-multicenter-retrospective-study
#24
JOURNAL ARTICLE
Biao Chen, Weiyong Sheng, Zhixin Wu, Bingqing Ma, Nan Cao, Xushu Li, Jia Yang, Xiaowei Yuan, Lizhao Yan, Gaobo Zhu, Yuanhong Zhou, Zhonghua Huang, Meiwei Zhu, Xuehui Ding, Hansong Du, Yanqing Wan, Xuan Gao, Xing Cheng, Peng Xu, Teng Zhang, Kaixiong Tao, Xiaoming Shuai, Ping Cheng, Yong Gao, Jinxiang Zhang
BACKGROUND: Currently, there is a lack of ideal risk prediction tools in the field of emergency general surgery (EGS). The American Association for the Surgery of Trauma recommends developing risk assessment tools specifically for EGS-related diseases. In this study, we sought to utilize machine learning (ML) algorithms to explore and develop a web-based calculator for predicting five perioperative risk events of eight common operations in EGS. METHOD: This study focused on patients with EGS and utilized electronic medical record systems to obtain data retrospectively from five centers in China...
March 15, 2024: International Journal of Surgery
https://read.qxmd.com/read/38481909/navigating-the-complexity-of-scoring-systems-in-sepsis-management-a-comprehensive-review
#25
REVIEW
Venkat Reddy, Harshitha Reddy, Rinkle Gemnani, Sunil Kumar, Sourya Acharya
This comprehensive review navigates the intricate landscape of sepsis scoring systems, aiming to provide healthcare professionals and researchers with a nuanced understanding of their role in contemporary sepsis management. Beginning with a succinct overview of sepsis, the review emphasizes the significance of scoring systems in standardizing assessments and guiding clinical decision-making. Through a detailed analysis of prominent systems such as SOFA, APACHE, and qSOFA, the review delineates their unique attributes, strengths, and limitations...
February 2024: Curēus
https://read.qxmd.com/read/38477001/comparison-of-the-recent-expres-score-weansnow-score-and-the-parsimonious-hacor-score-as-the-best-predictor-of-weaning-an-externally-validated-prospective-observational-study
#26
JOURNAL ARTICLE
Gautham Nayak, Souvik Chaudhuri, Sunil Ravindranath, Pratibha Todur
BACKGROUND: Since weaning failure is multifactorial, comprehensive weaning scores encompassing not only the respiratory component but also nonrespiratory aspects are quintessential for successful weaning prediction. MATERIALS AND METHODS: This was a single-center prospective observational study on 128 intensive care unit (ICU) patients undergoing spontaneous breathing trials (SBT). The extubation prediction score (ExPreS), heart rate, acidosis, consciousness, oxygenation, respiratory rate (HACOR), and weaning parameters, endotracheal tube size, arterial blood gas analysis, nutrition, secretions, neuromuscular affecting agents, obstructive airway problems and wakefulness (WEANSNOW) scores were compared for their diagnostic accuracy for successful weaning prediction...
March 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38476903/risk-factors-and-predictive-model-for-mortality-in-patients-undergoing-allogeneic-hematopoietic-stem-cell-transplantation-admitted-to-the-intensive-care-unit
#27
JOURNAL ARTICLE
Peihua Wu, Wenxuan Huo, Huiying Zhao, Jie Lv, Shan Lv, Youzhong An
Hematological malignant tumors represent a group of major diseases carrying a substantial risk to the lives of affected patients. Risk factors for mortality in critically ill patients have garnered substantial attention in recent research endeavors. The present research aimed to identify factors predicting intensive care unit (ICU) mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Furthermore, the present study analyzed and compared the mortality rate between patients undergoing haploidentical hematopoietic stem cell transplantation (Haplo-SCT) and those undergoing identical sibling donor (ISD) transplantation...
April 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38476769/spink1-is-a-potential-diagnostic-and-prognostic-biomarker-for-sepsis
#28
JOURNAL ARTICLE
Dexiu Chen, Zhangjing Shi, Xiaolan Gao, Yuxiang Yang, Xianying Lei, Yingchun Hu
PURPOSE: There are no satisfactory diagnostic biomarkers for sepsis. Accordingly, this study screened biomarkers valuable for sepsis diagnosis and prognosis using data-independent acquisition (DIA) combined with clinical data analysis. PATIENTS AND METHODS: Serine protease inhibitor Kazal-type 1 (SPINK1) is a differentially expressed protein that was screened using DIA and bioinformatics in sepsis patients (n = 22) and healthy controls (n = 10). The plasma SPINK1 levels were detected using an enzyme-linked immunosorbent assay (ELISA) in an expanded population (sepsis patients, n = 52; healthy controls, n = 10)...
2024: Infection and Drug Resistance
https://read.qxmd.com/read/38476550/comparison-of-acute-physiology-and-chronic-health-evaluation-apache-ii-and-american-college-of-surgeons-national-surgical-quality-improvement-program-acs-nsqip-scoring-system-in-predicting-postoperative-mortality-in-patients-undergoing-emergency-laparotomy
#29
JOURNAL ARTICLE
Pallavi Doda, Sukhyanti Kerai, Kanika Chauhan, Vineet Manchanda, Kirti N Saxena, Anurag Mishra
BACKGROUND AND AIMS: There is paucity of studies on preoperative risk assessment tools in patients undergoing emergency surgery. The present study evaluated the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) II, American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) surgical risk calculator and American Society of Anesthesiologists (ASA) physical status (PS) classification system in patients undergoing emergency exploratory laparotomy...
March 2024: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38476471/prognostic-value-of-macrophage-inflammatory-protein-3alpha-mip3-alpha-and-severity-scores-in-elderly-patients-with-sepsis
#30
JOURNAL ARTICLE
Min Liu, Yun-Jiao Duan, Ye Zhang, Jun Yang, Bing Wei, Junyu Wang
OBJECTIVE: This study examines the effectiveness of MIP-3alpha and severity scores in determining the prognosis of elderly sepsis patients. METHODS: From October 2020 to April 2021, a total of 171 elderly sepsis patients were admitted to the Emergency Department of the Shijingshan Branch of Beijing Chaoyang Hospital, Capital Medical University. According to the 28-day mortality rate, they were divided into two groups: survivors (48 cases) and deaths (123 cases)...
2024: Journal of Inflammation Research
https://read.qxmd.com/read/38476193/derivation-and-validation-of-a-quantitative-risk-prediction-model-for-weaning-and-extubation-in-neurocritical-patients
#31
JOURNAL ARTICLE
Weiling Cheng, Ning Zhang, Dongcheng Liang, Haoling Zhang, Lei Wang, Leqing Lin
BACKGROUND: Patients with severe neurological conditions are at high risk during withdrawal and extubation, so it is important to establish a model that can quantitatively predict the risk of this procedure. METHODS: By analyzing the data of patients with traumatic brain injury and tracheal intubation in the ICU of the affiliated hospital of Hangzhou Normal University, a total of 200 patients were included, of which 140 were in the modeling group and 60 were in the validation group...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38476066/clinical-characteristics-and-outcomes-of-obstetric-patients-transferred-directly-to-intensive-care-units
#32
JOURNAL ARTICLE
Saad Pirzada, Kimberly Boswell, Jerry Yang, Samantha Asuncion, Fernando Albelo, Amanda Tuchler, Lauren Becker, Allison Lankford, Emad Elsamadicy, Quincy K Tran
BACKGROUND: Medical complications in peripartum patients are uncommon. Often, these patients are transferred to tertiary care centers, but their conditions and outcomes are not well understood. Our study examined peripartum patients transferred to an intensive care unit (ICU) at an academic quaternary center. METHODS: We reviewed charts of adult, non-trauma, interhospital transfer (IHT) peripartum patients sent to an academic quaternary ICU between January 2017 and December 2021...
February 2024: Acute and critical care
https://read.qxmd.com/read/38469112/outcomes-of-critically-ill-patients-with-liver-failure-who-require-mechanical-ventilation-a-retrospective-single-center-study
#33
JOURNAL ARTICLE
Atsuyoshi Mita, Sari Shimizu, Takashi Ichiyama, Takateru Yamamoto, Akinori Yamaguchi, Kosuke Sonoda, Kotaro Mori, Tomokatsu Yamada, Hiroyuki Nakamura, Hiroshi Imamura
BACKGROUND AND AIMS: Critically ill patients with liver failure have high mortality. Besides the management of organ-specific complications, liver transplantation constitutes a definitive treatment. However, clinicians may hesitate to introduce mechanical ventilation for patients on liver transplantation waitlists because of poor prognosis. This study investigated the outcomes of intensive care and ventilation support therapy effects in patients with liver failure. METHODS: This single-center study retrospectively enrolled 32 consecutive patients with liver failure who were admitted to the intensive care unit from January 2014 to December 2020...
March 2024: Health Science Reports
https://read.qxmd.com/read/38463604/analysis-of-therapeutic-effects-on-type-ii-respiratory-failure-and-impact-on-blood-gas-changes-high-flow-nasal-oxygen-therapy-vs-non-invasive-positive-pressure-ventilation
#34
JOURNAL ARTICLE
Yongping Liu, Ning Liu, Ying Li, Lixiu Nie, Lin Li
OBJECTIVE: To evaluate the efficacy of high-flow nasal oxygen therapy (HFNO) vs. non-invasive positive pressure ventilation (NIPPV) in type II respiratory failure, and analyze their impact on blood gas parameters. METHODS: A retrospective analysis of 110 cases of type II respiratory failure treated from April 2021 to March 2023 categorized patients into control (NIPPV, n=50) and observation (HFNO, n=60) groups. Both groups received comprehensive nursing interventions...
2024: American Journal of Translational Research
https://read.qxmd.com/read/38462398/applicability-of-an-unsupervised-cluster-model-developed-on-first-wave-covid-19-patients-in-second-third-wave-critically-ill-patients
#35
JOURNAL ARTICLE
Alejandro Rodríguez, Josep Gómez, Álvaro Franquet, Sandra Trefler, Emili Díaz, Jordi Sole-Violán, Rafael Zaragoza, Elisabeth Papiol, Borja Suberviola, Montserrat Vallverdú, María Jimenez-Herrera, Antonio Albaya-Moreno, Alfonso Canabal Berlanga, María Del Valle Ortíz, Juan Carlos Ballesteros, Lucía López Amor, Susana Sancho Chinesta, Maria de Alba-Aparicio, Angel Estella, Ignacio Martín-Loeches, María Bodi
OBJECTIVE: To validate the unsupervised cluster model (USCM) developed during the first pandemic wave in a cohort of critically ill patients from the second and third pandemic waves. DESIGN: Observational, retrospective, multicentre study. SETTING: Intensive Care Unit (ICU). PATIENTS: Adult patients admitted with COVID-19 and respiratory failure during the second and third pandemic waves. INTERVENTIONS: None...
March 9, 2024: Medicina intensiva
https://read.qxmd.com/read/38457952/development-of-prognostic-models-for-predicting-90-day-neurological-function-and-mortality-after-cardiac-arrest
#36
JOURNAL ARTICLE
Guangqian Ding, Ailing Kuang, Zhongbo Zhou, Youping Lin, Yi Chen
BACKGROUND: The survivors of cardiac arrest experienced vary extent of hypoxic ischemic brain injury causing mortality and long-term neurologic disability. However, there is still a need to develop robust and reliable prognostic models that can accurately predict these outcomes. OBJECTIVES: To establish reliable models for predicting 90-day neurological function and mortality in adult ICU patients recovering from cardiac arrest. METHODS: We enrolled patients who had recovered from cardiac arrest at Binhaiwan Central Hospital of Dongguan, from January 2018 to July 2021...
February 19, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38456106/predictors-of-treatment-failure-and-mortality-among-patients-with-septic-shock-treated-with-meropenem-in-the-intensive-care-unit
#37
JOURNAL ARTICLE
Mohd Zulfakar Mazlan, Amar Ghassani Ghazali, Mahamarowi Omar, Najib Majdi Yaacob, Nik Abdullah Nik Mohamad, Mohamad Hasyizan Hassan, Wan Fadzlina Wan Muhd Shukeri
BACKGROUND: The aim of the study was to determine the predictors of meropenem treatment failure and mortality in the Intensive Care Unit (ICU). METHODS: This was a retrospective study, involving sepsis and septic shock patients who were admitted to the ICU and received intravenous meropenem. Treatment failure is defined as evidence of non-resolved fever, non-reduced total white cell (TWC), non-reduced C-reactive protein (CRP), subsequent culture negative and death in ICU...
February 2024: Malaysian Journal of Medical Sciences: MJMS
https://read.qxmd.com/read/38454797/prospective-multicenter-registry-based-study-on-thyroid-storm-the-guidelines-for-the-management-from-japan-are-useful
#38
JOURNAL ARTICLE
Yasushi Furukawa, Keiko Tanaka, Osamu Isozaki, Atsushi Suzuki, Tadao Iburi, Kumiko Tsuboi, Moritake Iguchi, Naotetsu Kanamoto, Kanshi Minamitani, Shu Wakino, Tetsurou Satoh, Satoshi Teramukai, Eizen Kimura, Yoshihiro Miyake, Takashi Akamizu
CONTEXT: The mortality rate in thyroid storm (TS) has been reported to be higher than 10%. OBJECTIVE: We aimed to evaluate the effectiveness of the 2016 guidelines for the management of TS proposed by the Japan Thyroid Association and Japan Endocrine Society. DESIGN: Prospective registry-based study through a secure web platform. SETTING: Prospective multicenter registry. PATIENTS AND MEASUREMENTS: Patients with new-onset TS were registered in the Research Electronic Data Capture (REDCap)...
March 8, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38448758/development-and-validation-of-multimodal-models-to-predict-the-30-day-mortality-of-icu-patients-based-on-clinical-parameters-and-chest-x-rays
#39
JOURNAL ARTICLE
Jiaxi Lin, Jin Yang, Minyue Yin, Yuxiu Tang, Liquan Chen, Chang Xu, Shiqi Zhu, Jingwen Gao, Lu Liu, Xiaolin Liu, Chenqi Gu, Zhou Huang, Yao Wei, Jinzhou Zhu
We aimed to develop and validate multimodal ICU patient prognosis models that combine clinical parameters data and chest X-ray (CXR) images. A total of 3798 subjects with clinical parameters and CXR images were extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and an external hospital (the test set). The primary outcome was 30-day mortality after ICU admission. Automated machine learning (AutoML) and convolutional neural networks (CNNs) were used to construct single-modal models based on clinical parameters and CXR separately...
March 6, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38442935/-establishment-and-analysis-of-an-early-prognosis-model-of-patients-with-acute-kidney-injury-in-intensive-care-unit
#40
JOURNAL ARTICLE
Yu'an Geng, Congmei Wang, Zhijing Xu, Lu Qi, Yangang Shi, Shiqiong Su, Kai Wang, Ruifang Liu
OBJECTIVE: To establish a predictive model for the progression of acute kidney injury (AKI) to stage 3 AKI (renal failure) in the intensive care unit (ICU), so as to assist physicians to make early and timely decisions on whether to intervene in advance. METHODS: A retrospective analysis was conducted. Thirty-eight patients with AKI admitted to the intensive care medicine of the Third People's Hospital of Henan Province from January 2018 to May 2023 were enrolled...
February 2024: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
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