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Fluid resusciation

Ki Hyuk Joo, In Sool Yoo, Jinwoong Lee, Seung Whan Kim, Seung Ryu, Yeon Ho You, Yong Chul Cho, Woon Jun Jeong, Byung Jun Ahn, Sung Uk Cho
OBJECTIVE: Critically ill patients sometimes require transport to another location. Longer intra-hospital transport time increases the risk of hemodynamic instability and associated complications. Therefore, reducing intra-hospital transport time is critical. Our objective was to evaluate whether or not a new device the easy tube arrange device (ETAD) has the potential to reduce intra-hospital transport time of critically ill patients. METHODS: We enrolled volunteers for this prospective randomized controlled study...
June 2016: Clinical and Experimental Emergency Medicine
Zhi-Yong Peng, Feihu Zhou, John A Kellum
BACKGROUND: The recent discovery of cell cycle arrest biomarkers, tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein 7 (IGFBP7), has led to a newly available clinical test for acute kidney injury. The performance of these markers in preclinical studies has not been established. Therefore, we sought to evaluate the performance of TIMP-2 and IGFBP7 in rats undergoing cecal ligation and puncture. METHODS: In this secondary analysis, we analyzed banked urine samples from 60 Sprague-Dawley rats undergoing cecal ligation and puncture (CLP)...
December 2016: Intensive Care Medicine Experimental
J Boldt, D Kling, B von Bormann, H H Scheld, G Hempelmann
Cardiovascular arrest may be followed by severe respiratory insufficiency due to an increase in the pressure in the pulmonary vascular system, an alteration in capillary permeability, or both. Extracorporeal circulation (ECC), on the other hand, can lead to a change in capillary integrity ('capillary leakage') caused by the unphysiologic perfusion patterns and/or activation of various mediator systems. Pulmonary hyperhydration (increased extravascular lung water [EVLW]) seems to be the most important factor limiting pulmonary function in this situation...
February 1988: Der Anaesthesist
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