Frédéric Brillant-Marquis, Émilie Proulx, Kayadri Ratnarajah, Aubert Lavoie, Amélie Gauthier, Rémi Gagnon, Jean-Nicolas Boursiquot, Nina Verreault, Louis Marois, Marc-Antoine Bédard, Martine Boivin, Pierre-Michel Bédard, Manale Ouakki, Gaston De Serres, Jean-Philippe Drolet
BACKGROUND: About 10% of patients have a penicillin allergy label, but less than 5% of them are actually allergic. Unnecessary penicillin avoidance is associated with serious medical consequences. Given the growing number of these labels, it is imperative that our diagnostic strategy for penicillin allergy be as efficient as possible. The validity of traditionally used skin tests (STs) has been questioned, whereas drug provocation testing (DPT), the criterion standard, without previous ST appears very safe in most cases...
February 2024: Journal of Allergy and Clinical Immunology in Practice