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Yi Zhong

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https://www.readbyqxmd.com/read/28819777/qingkailing-injection-for-treatment-of-children-pneumonia-induced-by-respiratory-syncytial-virus-a-meta-analysis-of-randomized-controlled-trials
#1
Shuai He, Wen-Shi Li, Ya-Jun Luo, Chen-Li Ye, Zhong-Yi Zhang
OBJECTIVE: To evaluate the efficacy and safety of Qingkailing Injection (, QKL) for treatment of children pneumonia caused by respiratory syncytial virus (RSV). METHODS: Randomized clinical trials (RCTs) comparing QKL with ribavirin injection in the treatment of children pneumonia induced by RSV were searched in PubMed, Science Direct, Cochrane Library, Chinese VIP database, CNKI and Wanfang databases from their inception to March 2014. Meta-analyses were performed using RevMan 5...
August 17, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28819748/lipoxin-a4-attenuates-bronchopulmonary-dysplasia-via-upregulation-of-let-7c-and-downregulation-of-tgf-%C3%AE-1-signaling-pathway
#2
Xiao-Qing Chen, Sheng-Hua Wu, Yan-Yan Luo, Bing-Jie Li, Shu-Jun Li, Hong-Yan Lu, Rui Jin, Zhong-Yi Sun
Transforming growth factor-β (TGF-β) superfamily members are key regulators for lung development and progress of bronchopulmonary dysplasia (BPD). The mechanisms by which lipoxin A4 (LXA4) attenuates development of BPD have not been clarified. Neonatal murine BPD models were inducted by hyperoxia treatment. Neonatal mice were exposed to room air or 85% O2 hyperoxia with or without treatment with 5S,6R-methyl-LXA4 or anti-TGF-β antibodies. Mouse lung epithelial cells (MLE-12 cells) and mouse embryonic fibroblasts (NIH/3T3 cells) were cultured in room air or 85% O2 followed by treatment of LXA4, anti-TGF-β antibodies, and let-7c mimic/anti-microRNA transfections...
August 17, 2017: Inflammation
https://www.readbyqxmd.com/read/28814522/characterization-of-cis-acting-rna-elements-of-zika-virus-by-using-a-self-splicing-ribozyme-dependent-infectious-clone
#3
Zhong-Yu Liu, Jiu-Yang Yu, Xing-Yao Huang, Hang Fan, Xiao-Feng Li, Yong-Qiang Deng, Xue Ji, Meng-Li Cheng, Qing Ye, Hui Zhao, Jian-Feng Han, Xiao-Ping An, Tao Jiang, Bo Zhang, Yi-Gang Tong, Cheng-Feng Qin
Zika virus (ZIKV) has caused significant outbreaks and epidemics in the Americas recently, raising global concern due to its ability to cause microcephaly and other neurological complications. A stable and efficient infectious clone of ZIKV is urgently needed. However, the instability and toxicity of flavivirus cDNA clones in E. coli hosts has hindered the development of ZIKV infectious clones. Herein, using a novel self-splicing ribozyme-based strategy, we have generated a stable infectious cDNA clone of a contemporary ZIKV strain imported from Venezuela to China in 2016...
August 16, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28812244/fabrication-of-ordered-nanopattern-by-using-abc-triblock-copolymer-with-salt-in-toluene
#4
Hailiang Huang, Benbin Zhong, Xihong Zu, Hongsheng Luo, Wenjing Lin, Minghai Zhang, Yazhou Zhong, Guobin Yi
Ordered nanopatterns of triblock copolymer polystyrene-block-poly(2-vinylpyridine)-block- poly (ethylene oxide)(PS-b-P2VP-b-PEO) have been achieved by the addition of lithium chloride (LiCl). The morphological and structural evolution of PS-b-P2VP-b-PEO/LiCl thin films were systematically investigated by varying different experimental parameters, including the treatment for polymer solution after the addition of LiCl, the time scale of ultrasonic treatment and the molar ratio of Li(+) ions to the total number of oxygen atoms (O) in PEO block and the nitrogen atoms (N) in P2VP block...
August 15, 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28812170/a-novel-approach-to-utilize-icariin-as-icariin-derived-ecm-on-small-intestinal-submucosa-scaffold-for-bone-repair
#5
Mei Li, Chi Zhang, Yi Zhong, Jiyuan Zhao
Icariin (Ic) has been demonstrated as a potent osteoinductive compound for bone tissue engineering. However, toxic side effects of the drug and poor biocompatibility of drug delivery systems (DDSs) still limit its application for bone repair in the clinic. To overcome these disadvantages and utilize the osteoinductivity of Ic, we developed a novel method to utilize Ic as an Ic-derived osteoinductive extracellular matrix (ECM) on small intestinal submucosa (SIS) (Ic-ECM-SIS). The generated Ic-ECM-SIS scaffolds, as a natural construct, exhibited much better biocompatibility (including cell adhesion, cell survival and cell proliferation) than Ic-SIS scaffolds generated by traditional DDSs...
August 15, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28811627/impact-of-ocean-warming-on-tropical-cyclone-size-and-its-destructiveness
#6
Yuan Sun, Zhong Zhong, Tim Li, Lan Yi, Yijia Hu, Hongchao Wan, Haishan Chen, Qianfeng Liao, Chen Ma, Qihua Li
The response of tropical cyclone (TC) destructive potential to global warming is an open issue. A number of previous studies have ignored the effect of TC size change in the context of global warming, which resulted in a significant underestimation of the TC destructive potential. The lack of reliable and consistent historical data on TC size limits the confident estimation of the linkage between the observed trend in TC size and that in sea surface temperature (SST) under the background of global climate warming...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811160/high-efficiency-removal-of-lead-from-wastewater-by-biochar-derived-from-anaerobic-digestion-sludge
#7
Shih-Hsin Ho, Yi-di Chen, Zhong-Kai Yang, Dillirani Nagarajan, Jo-Shu Chang, Nan-Qi Ren
The properties of biochar derived from waste activated sludge and anaerobic digestion sludge under pyrolysis temperature varying from 400°C to 800°C were investigated. The heavy metals adsorption efficiency of the sludge-derived biochar was also examined. Among the biochar samples tested, ADSBC600 possessing highly porous structure, special surface chemical behaviors and high thermal stability was found to remove Pb(2+) from aqueous solutions efficiently with an adsorption capacity of 51.20mg/g. The Pb(2+) adsorption kinetics and isotherm for ADSBC600 can be described using the pseudo second-order model and Langmuir isotherm, respectively...
August 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28810579/microrna-375-targets-pax6-and-inhibits-the-viability-migration-and-invasion-of-human-breast-cancer-mcf-7-cells
#8
Qiongyan Zou, Wenjun Yi, Jianghai Huang, Fenfen Fu, Gannong Chen, Dewu Zhong
MicroRNAs (miRs) are a type of small non-coding RNA that serve crucial roles in the development and progression of breast cancer. However, the exact role and underlying molecular mechanism of miR-375 in mediating the growth and metastasis of breast cancer remains unknown. In the present study, reverse transcription-quantitative polymerase chain reaction and western blot analysis were conducted to examine RNA and protein expression. A luciferase reporter assay was performed to determine the association between miR-375 and paired box 6 (PAX6)...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28807839/characterization-of-fm2382-from-fulvimarina-manganoxydans-sp-nov-8047-with-potential-enzymatic-decontamination-of-sulfur-mustard
#9
Yuan-Zhong Zhao, Xuan Guo, Jin-Yi Zhong, Nan Guo, Lin-Cai Chen, Zhi-Yang Dong
Sulfur mustard (SM) can be hydrolyzed by haloalkane dehalogenases such as DhaA, LinB and DmbA. However, the low resistance to the elevated temperatures limited the practical application of haloalkane dehalogenases. Here we reported a new thermotolerant dehalogenase FM2382 from Fulvimarina manganoxydans sp. nov. 8047. The specific activity of FM2382 to SM is 0.6 U/mg. FM2382 possessed high heat stability (45 °C) in slight alkali environment (pH 7.5) and retained approximately 50% activity after incubation at 70 °C for 40 min...
August 11, 2017: Protein Expression and Purification
https://www.readbyqxmd.com/read/28806735/molecular-characterization-and-multi-locus-genotypes-of-enterocytozoon-bieneusi-from-captive-red-kangaroos-macropus-rfus-in-jiangsu-province-china
#10
Zhijun Zhong, Yinan Tian, Yuan Song, Lei Deng, Junxian Li, Zhihua Ren, Xiaoping Ma, Xiaobin Gu, Changliang He, Yi Geng, Guangneng Peng
Enterocytozoon bieneusi is the most common pathogen of microsporidian species infecting humans worldwide. Although E. bieneusi has been found in a variety of animal hosts, information on the presence of E. bieneusi in captive kangaroos in China is limited. The present study was aimed at determining the occurrence and genetic diversity of E. bieneusi in captive kangaroos. A total of 61 fecal specimens (38 from red kangaroos and 23 from grey kangaroos) were collected from Nanjing Hongshan Forest Zoo and Hongshan Kangaroo Breeding Research Base, Jiangsu province, China...
2017: PloS One
https://www.readbyqxmd.com/read/28804718/cd36-gene-polymorphisms-are-associated-with-intracerebral-hemorrhage-susceptibility-in-a-han-chinese-population
#11
Qiu-Wen Gong, Mao-Fan Liao, Liang Liu, Xiao-Yi Xiong, Qin Zhang, Qi Zhong, Kai Zhou, Yuan-Rui Yang, Zhao-You Meng, Chang-Xiong Gong, Rui Xu, Qing-Wu Yang
The CD36 gene encodes a membrane glycoprotein (type B scavenger receptor, SR-B2) that plays a crucial role in lipid sensing, innate immunity, atherogenesis, and glycolipid metabolism. In this study, we aimed to investigate the association between CD36 gene polymorphisms and intracerebral hemorrhage (ICH) in a Han Chinese population. We performed genotype and allele analyses for eleven single nucleotide polymorphisms (SNPs) of CD36 in a case-controlled study involving 292 ICH patients and 298 control participants...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28797153/-chorionic-villus-cell-culture-and-karyotype-analysis-in-1-983-cases-of-spontaneous-miscarriage
#12
S M Yuan, C Liao, D Z Li, J Z Huang, S Y Hu, M Ke, H Z Zhong, C X Yi
Objective: To investigate the relationship between spontaneous miscarriage and embryonic chromosome abnormalities, and to evaluate the clinical application of karyotype analysis by chorionic villus cell culture. Methods: The chorionic villus karyotype of 1 983 cases of miscarriage from January 2010 to July 2016 in Guangzhou Women and Children's Mecical Center were analyzed retrospectively. The miscarried chorionic villi were obtained by curettage under sterilized condition. The chromosome specimens were prepared after chorionic villus cell culture...
July 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28792059/solution-synthesis-and-phase-control-of-inorganic-perovskites-for-high-performance-optoelectronic-devices
#13
Jia Liang, Caixing Wang, Peiyang Zhao, Zhipeng Lu, Yue Ma, Zhaoran Xu, Yanrong Wang, Hongfei Zhu, Yi Hu, Guoyin Zhu, Lianbo Ma, Tao Chen, Zuoxiu Tie, Jie Liu, Zhong Jin
An efficient method to synthesize well-crystallized inorganic cesium lead halide perovskites (CsPbX3, X = I or Br) with high yield and high reproducibility was proposed. Notably, the as-prepared CsPbI3 in the yellow orthorhombic phase (y-CsPbI3) can be easily converted to the black cubic perovskite phase CsPbI3 (b-CsPbI3) after thermal annealing. Furthermore, two-terminal photodetectors and all-inorganic perovskite solar cells based on b-CsPbI3 were fabricated, exhibiting high performances.
August 9, 2017: Nanoscale
https://www.readbyqxmd.com/read/28791835/ifn-%C3%AE-induces-senescence-like-characteristics-in-mouse-bone-marrow-mesenchymal-stem-cells
#14
Zhou Xin Yang, Gen Xiang Mao, Jing Zhang, Xiao Lin Wen, Bing Bing Jia, Yi Zhong Bao, Xiao Ling Lv, Ya Zhen Wang, Guo Fu Wang
BACKGROUND: Mesenchymal stem cells (MSC) are considered promising in tissue repair and regeneration medicine due to their proliferation and differentiation ability. Many properties of MSC are affected by cytokines, and IFN-γ has been shown to regulate MSC in many aspects. Senescence affects the proliferation, differentiation and cytokine secretion of MSC. OBJECTIVES: To investigate the effects of IFN-γ on the senescence-associated properties of MSC. MATERIAL AND METHODS: The MSC used in our study were isolated from the bone marrow (BM) of mice...
March 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790416/enhancing-structural-robustness-of-scale-free-networks-by-information-disturbance
#15
Jun Wu, Suo-Yi Tan, Zhong Liu, Yue-Jin Tan, Xin Lu
Many real-world systems can be described by scale-free networks with power-law degree distributions. Scale-free networks show a "robust yet fragile" feature due to their heterogeneous degree distributions. We propose to enhance the structural robustness of scale-free networks against intentional attacks by changing the displayed network structure information rather than modifying the network structure itself. We first introduce a simple mathematical model for attack information and investigate the impact of attack information on the structural robustness of scale-free networks...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28782029/eye-motion-triggered-self-powered-mechnosensational-communication-system-using-triboelectric-nanogenerator
#16
Xianjie Pu, Hengyu Guo, Jie Chen, Xue Wang, Yi Xi, Chenguo Hu, Zhong Lin Wang
Mechnosensational human-machine interfaces (HMIs) can greatly extend communication channels between human and external devices in a natural way. The mechnosensational HMIs based on biopotential signals have been developing slowly owing to the low signal-to-noise ratio and poor stability. In eye motions, the corneal-retinal potential caused by hyperpolarization and depolarization is very weak. However, the mechanical micromotion of the skin around the corners of eyes has never been considered as a good trigger signal source...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28777311/five-new-phenolic-compounds-with-antioxidant-activities-from-the-medicinal-insect-blaps-rynchopetera
#17
Huai Xiao, Tian-Peng Yin, Jian-Wei Dong, Xiu-Mei Wu, Qing Luo, Jian-Rong Luo, Le Cai, Zhong-Tao Ding
Five new phenolic compounds rynchopeterines A-E (1-5), in addition to thirteen known phenolics, were isolated from Blaps rynchopetera Fairmaire, a kind of medicinal insect utilized by the Yi Nationality in Yunnan Province of China. Their structures were established on the basis of extensive spectroscopic analyses (1D and 2D NMR, HR-MS, IR) along with calculated electronic circular dichroism method. Rynchopeterines A-E (1-4) exhibited significant antioxidant activities with IC50 values of 7.67-12.3 μg/mL measured by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay...
August 4, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28776539/characteristics-management-and-outcomes-of-acute-heart-failure-in-the-emergency-department-a-multicenter-registry-study-with-1-year-follow-up-in-a-chinese-cohort-in-beijing
#18
Guo-Gan Wang, Si-Jia Wang, Jian Qin, Chun-Sheng Li, Xue-Zhong Yu, Hong Shen, Li-Pei Yang, Yan Fu, Ya-An Zheng, Bin Zhao, Dong-Min Yu, Fu-Jun Qin, De-Gui Zhou, Ying Li, Fu-Jun Liu, Wei Li, Wei Zhao, Xin Gao, Zheng Wang, Ming Jin, Hong Zeng, Yi Li, Guo-Xing Wang, Hong Zhou, Xiao-Lu Sun, Peng-Bo Wang, Kam-Sang Woo
BACKGROUND: The emergency department (ED) has a pivotal influence on the management of acute heart failure (AHF), but data concerning current ED management are scarce. This Beijing AHF Registry Study investigated the characteristics, ED management, and short- and long-term clinical outcomes of AHF. METHODS: This prospective, multicenter, observational study consecutively enrolled 3335 AHF patients who visited 14 EDs in Beijing from January 1, 2011, to September 23, 2012...
August 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28773010/synthesis-of-au-np-mos%C3%A2-quantum-dots-core-shell-nanocomposites-for-sers-bio-analysis-and-label-free-bio-imaging
#19
Xixi Fei, Zhiming Liu, Yuqing Hou, Yi Li, Guangcun Yang, Chengkang Su, Zhen Wang, Huiqing Zhong, Zhengfei Zhuang, Zhouyi Guo
In this work, we report a facile method using MoS₂ quantum dots (QDs) as reducers to directly react with HAuCl₄ for the synthesis of Au nanoparticle@MoS₂ quantum dots (Au NP@MoS₂ QDs) core@shell nanocomposites with an ultrathin shell of ca. 1 nm. The prepared Au NP@MoS₂ QDs reveal high surface enhanced Raman scattering (SERS) performance regarding sensitivity as well as the satisfactory SERS reproducibility and stability. The limit of detection of the hybrids for crystal violet can reach 0.5 nM with a reasonable linear response range from 0...
June 13, 2017: Materials
https://www.readbyqxmd.com/read/28772119/the-biology-of-forgetting-a-perspective
#20
REVIEW
Ronald L Davis, Yi Zhong
Pioneering research studies, beginning with those using Drosophila, have identified several molecular and cellular mechanisms for active forgetting. The currently known mechanisms for active forgetting include neurogenesis-based forgetting, interference-based forgetting, and intrinsic forgetting, the latter term describing the brain's chronic signaling systems that function to slowly degrade molecular and cellular memory traces. The best-characterized pathway for intrinsic forgetting includes "forgetting cells" that release dopamine onto engram cells, mobilizing a signaling pathway that terminates in the activation of Rac1/Cofilin to effect changes in the actin cytoskeleton and neuron/synapse structure...
August 2, 2017: Neuron
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