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https://www.readbyqxmd.com/read/28930140/identification-of-phlogacantholide-c-as-a-novel-adam10-enhancer-from-traditional-chinese-medicinal-plants
#1
Myriam Meineck, Florian Schuck, Sara Abdelfatah, Thomas Efferth, Kristina Endres
Background: Alzheimer's disease is one of the most prevalent dementias in the elderly population with increasing numbers of patients. One pivotal hallmark of this disorder is the deposition of protein aggregates stemming from neurotoxic amyloid-beta peptides. Synthesis of those peptides has been efficiently prevented in AD model mice by activation of an enzyme called alpha-secretase. Therefore, drugs with the capability to increase the expression of this enzyme, named ADAM10, have been suggested as a valuable therapeutic medication...
December 5, 2016: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#2
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28916930/tongue-image-analysis-and-its-mobile-app-development-for-health-diagnosis
#3
Ratchadaporn Kanawong, Tayo Obafemi-Ajayi, Dahai Liu, Meng Zhang, Dong Xu, Ye Duan
Computer-aided diagnosis provides a medical procedure that assists physicians in interpretation of medical images. This work focuses on computer-aided tongue image analysis specifically, based on Traditional Chinese Medicine (TCM). Tongue diagnosis is an important component of TCM. Computerized tongue diagnosis can aid medical practitioners in capturing quantitative features to improve reliability and consistency of diagnosis. Recently, researchers have started to develop computer-aided tongue analysis algorithms based on new advancement in digital photogrammetry, image analysis, and pattern recognition technologies...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28912113/mobile-augmented-reality-as-a-feature-for-self-oriented-blended-learning-in-medicine-randomized-controlled-trial
#4
Christoph Noll, Ute von Jan, Ulrike Raap, Urs-Vito Albrecht
BACKGROUND: Advantages of mobile Augmented Reality (mAR) application-based learning versus textbook-based learning were already shown in a previous study. However, it was unclear whether the augmented reality (AR) component was responsible for the success of the self-developed app or whether this was attributable to the novelty of using mobile technology for learning. OBJECTIVE: The study's aim was to test the hypothesis whether there is no difference in learning success between learners who employed the mobile AR component and those who learned without it to determine possible effects of mAR...
September 14, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28894653/a-proposal-for-updated-standards-of-photographic-documentation-in-aesthetic-medicine
#5
Lukas Prantl, Dirk Brandl, Patricia Ceballos
In 1998, DiBernardo et al. published a very helpful standardization of comparative (before and after) photographic documentation. These standards prevail to this day. Although most of them are useful for objective documentation of aesthetic results, there are at least 3 reasons why an update is necessary at this time: First, DiBernardo et al. focused on the prevalent standards of medical photography at that time. From a modern perspective, these standards are antiquated and not always correct. Second, silver-based analog photography has mutated into digital photography...
August 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28893725/improvements-in-patient-acceptance-by-hospitals-following-the-introduction-of-a-smartphone-app-for-the-emergency-medical-service-system-a-population-based-before-and-after-observational-study-in-osaka-city-japan
#6
Yusuke Katayama, Tetsuhisa Kitamura, Kosuke Kiyohara, Taku Iwami, Takashi Kawamura, Junichi Izawa, Koichiro Gibo, Sho Komukai, Sumito Hayashida, Takeyuki Kiguchi, Mitsuo Ohnishi, Hiroshi Ogura, Takeshi Shimazu
BACKGROUND: Recently, the number of ambulance dispatches has been increasing in Japan, and it is therefore difficult for hospitals to accept emergency patients smoothly and appropriately because of the limited hospital capacity. To facilitate the process of requesting patient transport and hospital acceptance, an emergency information system using information technology (IT) has been built and introduced in various communities. However, its effectiveness has not been thoroughly revealed...
September 11, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28890223/a-new-iphone-%C3%A2-application-for-measuring-active-craniocervical-range-of-motion-in-patients-with-non-specific-neck-pain-a-reliability-and-validity-study
#7
Mohammad Reza Pourahmadi, Rasool Bagheri, Morteza Taghipour, Ismail Ebrahimi Takamjani, Javad Sarrafzadeh, Mohammad Ali Mohseni-Bandpei
BACKGROUND CONTEXT: Measurement of cervical spine range of motion (ROM) is often considered to be an essential component of cervical spine physiotherapy assessment. PURPOSE: To investigate the reliability and validity of an iPhone(®) app (Goniometer Pro(©)) for measuring active craniocervical ROM (ACCROM) in patients with non-specific neck pain. STUDY DESIGN/SETTING: A cross-sectional study was conducted at the musculoskeletal biomechanics laboratory located at Iran University of Medical Sciences...
September 7, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28888420/transition-to-residency-the-successful-development-and-implementation-of-a-nonclinical-elective-in-perioperative-management
#8
Heather McDonald, Nada Gawad, Isabelle Raîche, Fraser D Rubens
OBJECTIVE: Few medical school programs in Canada address challenges related to the significant increase in responsibility for patient care between medical school and residency. This is particularly important in surgery and anesthesia due to the high-acuity care required during the perioperative period. The purpose of this study was to develop and assess a program that would help students transition to surgical and anesthesia residencies, in terms of knowledge acquisition, clinical decision-making skills, and subjective preparedness...
September 6, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28886812/smartphone-based-applications-for-skin-monitoring-and-melanoma-detection
#9
REVIEW
Elizabeth Chao, Chelsea K Meenan, Laura K Ferris
With the advancement of mobile technologies, smartphone applications (apps) have become widely available and gained increasing attention as a novel tool to deliver dermatologic care. This article presents a review of various apps for skin monitoring and melanoma detection and a discussion of current limitations in the field of dermatology. Concerns regarding quality, transparency, and reliability have emerged because there are currently no established quality standards or regulatory oversight of mobile medical apps...
October 2017: Dermatologic Clinics
https://www.readbyqxmd.com/read/28885637/-is-there-an-app-for-that-orthopaedic-patient-preferences-for-a-smartphone-application
#10
Jonathan R Datillo, Daniel J Gittings, Matthew Sloan, William M Hardaker, Matthew J Deasey, Neil P Sheth
BACKGROUND: Patients are seeking out medical information on the Internet and utilizing smartphone health applications ("apps"). Smartphone use has exponentially increased among orthopaedic surgeons and patients. Despite this increase, patients are rarely directed to specific apps by physicians. No study exists querying patient preferences for a patient-centered, orthopaedic smartphone application. OBJECTIVES: The purpose of this study is to 1) determine Internet use patterns amongst orthopaedic patients; 2) ascertain access to and use of smartphones; and 3) elucidate what features orthopaedic patients find most important in a smartphone application...
August 16, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28881071/quantity-over-quality-findings-from-a-systematic-review-and-environmental-scan-of-patient-decision-aids-on-early-abortion-methods
#11
Kyla Z Donnelly, Glyn Elwyn, Rachel Thompson
BACKGROUND: The availability and effectiveness of decision aids (DAs) on early abortion methods remain unknown, despite their potential for supporting women's decision making. OBJECTIVE: To describe the availability, impact and quality of DAs on surgical and medical early abortion methods for women seeking induced abortion. SEARCH STRATEGY: For the systematic review, we searched MEDLINE, Cochrane Library, CINAHL, EMBASE and PsycINFO. For the environmental scan, we searched Google and App Stores and consulted key informants...
September 7, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28872765/digital-therapy-in-diabetes
#12
REVIEW
Avivit Cahn, Amit Akirov, Itamar Raz
Diabetes care is largely dependent on patient self-management and empowerment, given that patients with diabetes must make numerous daily decisions of what to eat, when to exercise, and determine their insulin dose and timing if required. Additionally, patients and providers are generating vast amounts of data from many sources including electronic medical records, insulin pumps, sensors, glucometers, other wearables, as well as evolving genomic, proteomic, metabolomic and microbiomic data. Multiple digital tools and apps have been developed to assist patients to choose wisely, as well as enhance their compliance by employing motivational tools and incorporating incentives from social media and gaming techniques...
September 5, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28864694/labtracker-a-medical-smartphone-app-for-the-interpretation-of-consecutive-laboratory-results-an-external-validation-study
#13
Judith M Hilderink, Roger J M W Rennenberg, Floris H M Vanmolkot, Otto Bekers, Richard P Koopmans, Steven J R Meex
OBJECTIVES: When monitoring patients over time, clinicians may struggle to distinguish 'real changes' in consecutive blood parameters from so-called natural fluctuations. In practice, they have to do so by relying on their clinical experience and intuition. We developed Labtracker+, a medical app that calculates the probability that an increase or decrease over time in a specific blood parameter is real, given the time between measurements. DESIGN: We presented patient cases to 135 participants to examine whether there is a difference between medical students, residents and experienced clinicians when it comes to interpreting changes between consecutive laboratory results...
September 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28856834/disparities-in-hypertension-and-cardiovascular-disease-in-blacks-the-critical-role-of-medication-adherence
#14
REVIEW
Keith C Ferdinand, Kapil Yadav, Samar A Nasser, Helene D Clayton-Jeter, John Lewin, Dennis R Cryer, Fortunato Fred Senatore
Blacks are two to three times as likely as whites to die of preventable heart disease and stroke. Declines in mortality from heart disease have not eliminated racial disparities. Control and effective treatment of hypertension, a leading cause of cardiovascular disease, among blacks is less than in whites and remains a challenge. One of the driving forces behind this racial/ethnic disparity is medication nonadherence whose cause is embedded in social determinants. Eight practical approaches to addressing medication adherence with the potential to attenuate disparities were identified and include: (1) patient engagement strategies, (2) consumer-directed health care, (3) patient portals, (4) smart apps and text messages, (5) digital pillboxes, (6) pharmacist-led engagement, (7) cardiac rehabilitation, and (8) cognitive-based behavior...
August 30, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28855857/a-health-information-system-for-scalable-and-comprehensive-assessment-of-well-being-a-multidisciplinary-team-solution
#15
Leming Zhou, Valerie Watzlaf, Paul Abernathy, Mervat Abdelhak
To improve the health and well-being of the medically underserved in a free clinic in Pittsburgh, Pennsylvania, a multidisciplinary team representing several health information management and information technology (IT) professionals, including faculty, students, researchers, and clinicians, created a novel IT system called imHealthy. The imHealthy system includes four critical components: a multidomain well-being questionnaire, a mobile app for data collection and tracking, a customization of an open-source electronic health record (EHR), and a data integration and well-being evaluation program leading to recommendations for personalized interventions to caregivers serving the medically underserved...
2017: Perspectives in Health Information Management
https://www.readbyqxmd.com/read/28855796/medical-decision-making-processes-and-online-behaviors-among-cannabis-dispensary-staff
#16
Nicholas C Peiper, Camille Gourdet, Angélica Meinhofer, Amanda Reiman, Nicco Reggente
BACKGROUND: Most cannabis patients engage with dispensary staff, like budtenders, for medical advice on cannabis. Yet, little is known about these interactions and how the characteristics of budtenders affect these interactions. This study investigated demographics, workplace characteristics, medical decision-making, and online behaviors among a sample of budtenders. METHODS: Between June and September 2016, a cross-sectional Internet survey was administered to budtenders in the San Francisco Bay Area and Greater Los Angeles...
2017: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/28854054/e-health-in-palliative-care-review-of-literature-google-play-and-app-store
#17
Sara Pinto, Sílvia Caldeira, José Carlos Martins
AIM: To analyse the use of e-Health technologies and mobile apps in palliative care (PC). METHODS: Search on PubMed, using 'telemedicine', 'ehealth', 'mobile health', 'telecare', 'health information systems' and 'palliative care'. Original Portuguese, Spanish, French and English papers were included. Google Play and App Store (iOS) were searched for mobile apps using 'palliative care', 'medical apps' and 'symptom management'. RESULTS: Twenty-five papers and forty mobile apps were analysed...
August 2, 2017: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/28838887/the-use-of-mobile-apps-and-sms-messaging-as-physical-and-mental-health-interventions-systematic-review
#18
Amy Leigh Rathbone, Julie Prescott
BACKGROUND: The initial introduction of the World Wide Web in 1990 brought around the biggest change in information acquisition. Due to the abundance of devices and ease of access they subsequently allow, the utility of mobile health (mHealth) has never been more endemic. A substantial amount of interactive and psychoeducational apps are readily available to download concerning a wide range of health issues. mHealth has the potential to reduce waiting times for appointments; eradicate the need to meet in person with a clinician, successively diminishing the workload of mental health professionals; be more cost effective to practices; and encourage self-care tactics...
August 24, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28834800/developing-a-mobile-app-for-neuroscience-nurses
#19
Christi D DeLemos
In this month's Magnet® Perspectives column, the recipient of the 2016 Magnet Nurse of the Year® Award for New Knowledge, Innovations, and Improvements shares her journey to develop and disseminate a mobile application for nurses who care for neurological patients. "Neuroscience nurse" puts the latest, evidence-based information at the fingertips of nurses at the bedside in an effort to increase confidence when caring for patients with stroke, traumatic brain injury, and other neurological impairments.Nurse practitioner Christi DeLemos explains where she got the idea and how she went about implementing it...
September 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28830854/a-mobile-device-app-to-reduce-medication-errors-and-time-to-drug-delivery-during-pediatric-cardiopulmonary-resuscitation-study-protocol-of-a-multicenter-randomized-controlled-crossover-trial
#20
Johan N Siebert, Frederic Ehrler, Christian Lovis, Christophe Combescure, Kevin Haddad, Alain Gervaix, Sergio Manzano
BACKGROUND: During pediatric cardiopulmonary resuscitation (CPR), vasoactive drug preparation for continuous infusions is complex and time-consuming. The need for individual specific weight-based drug dose calculation and preparation places children at higher risk than adults for medication errors. Following an evidence-based and ergonomic driven approach, we developed a mobile device app called Pediatric Accurate Medication in Emergency Situations (PedAMINES), intended to guide caregivers step-by-step from preparation to delivery of drugs requiring continuous infusion...
August 22, 2017: JMIR Research Protocols
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