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https://www.readbyqxmd.com/read/29786124/evaluation-of-the-relationship-between-flap-tension-and-tissue-perfusion-in-implant-based-breast-reconstruction-using-laser-assisted-indocyanine-green-angiography
#1
Chae-Eun Yang, Soon Won Chung, Dong Won Lee, Dae Hyun Lew, Seung Yong Song
BACKGROUND: For implant-based breast reconstruction, inadequate tissue perfusion may cause devastating complications. Tissue tension by inadequate implant volume may reduce tissue perfusion by stretching and collapsing the capillaries. The SPY system is used to perform intraoperative fluorescence angiography with indocyanine green to assess visually the blood flow and evaluate tissue perfusion. However, there is no report yet about how mastectomy flap perfusion changes with the expander-filling volume...
May 21, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29784600/breast-reconstruction-after-mastectomy-a-survey-of-surgeons-and-patients-perceptions
#2
Ariffuddin Ishak, Maya Mazuwin Yahya, Ahmad Sukari Halim
BACKGROUND: Breast reconstruction after mastectomy is important in breast cancer care. MATERIALS AND METHODS: A cross-sectional study was designed to assess surgeons' and patients' perceptions toward breast reconstruction. Questionnaires were distributed to general and breast surgeons in East Coast Malaysian hospitals and Hospital Kuala Lumpur and to postmastectomy patients with and without breast reconstruction at the Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II...
April 28, 2018: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29782518/objective-assessment-of-flap-volume-changes-and-aesthetic-results-after-adjuvant-radiation-therapy-in-patients-undergoing-immediate-autologous-breast-reconstruction
#3
Yujin Myung, Yousung Son, Tae-Hyun Nam, Eunyoung Kang, Eun-Kyu Kim, In Ah Kim, Keun-Yong Eom, Chan Yeong Heo, Jae Hoon Jeong
BACKGROUND: The use of immediate breast reconstruction and adjuvant radiation therapy is increasing in breast cancer patients. This study aimed to analyze the aesthetic outcome and changes in flap volume in patients with breast cancer undergoing radiation therapy of the surgical site after immediate autologous tissue reconstruction. METHODS: Immediate abdominal free flap breast reconstruction following unilateral mastectomy was performed in 42 patients; 21 patients received adjuvant radiation (study group) and 21 patients did not (control group)...
2018: PloS One
https://www.readbyqxmd.com/read/29782396/risk-factors-for-delays-in-adjuvant-chemotherapy-following-immediate-breast-reconstruction
#4
Oriana Cohen, Gretl Lam, Mihye Choi, Daniel Ceradini, Nolan Karp
BACKGROUND: Concerns exist that immediate breast reconstruction may delay adjuvant chemotherapy initiation, impacting oncologic outcomes. Here, we determine how post-operative complications impact chemotherapy timing, and identify factors associated with greater risk for delays. METHODS: Retrospective chart review identified patients undergoing immediate breast reconstruction and adjuvant chemotherapy at a single institution from 2010 to 2015. Patients were analyzed based on occurrence of post-operative complications and time to chemotherapy...
May 15, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29781858/axillary-lymphadenectomy-and-wound-complications-in-implant-based-breast-reconstruction
#5
Matthew T Joy, Matthew D Rich, Kurtis E Moyer
BACKGROUND: The most common method of breast reconstruction in the United States today is implant-based reconstruction. However, reported complication rates are high, from 30% to 50%. Thus, it is important for reconstructive surgeons to identify factors associated with or contributing to wound complications after breast reconstruction. This study sought to identify associations between axillary lymph node dissection and postoperative wound complications in implant-based breast reconstruction...
May 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29781849/breast-reconstruction-among-commercially-insured-women-with-breast-cancer-in-the-united-states
#6
Andrea Barnow, Todd Canfield, Ray Liao, Sashi Yadalam, Iftekhar Kalsekar, Rahul Khanna
INTRODUCTION: This study evaluated trends related to breast reconstruction and the factors associated with reconstruction. METHODS: Women with breast cancer aged 19 to 64 years who underwent a mastectomy procedure between July 1, 2011, and September 30, 2014, were identified from the MarketScan Commercial Claims and Encounters Database. The first date of surgical procedure during this period was defined as the index date. Continuous enrollment during the 12-month preindex and postindex period was required, and the patient sample was followed for 12 months postindex...
May 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29781241/timing-of-radiation-therapy-in-nipple-sparing-mastectomy-influences-outcomes-and-patient-reported-quality-of-life
#7
Michael Sosin, Aiste Gulla, Lindsay Potdevin, Solange E Cox, Alex J Bartholomew, Sulakshana Seevaratnam, Manisha Sigdel, Troy A Pittman, Shawna C Willey, Eleni A Tousimis
The aim of this study is to assess the complication profile and impact on patient-reported quality of life in those undergoing nipple-sparing mastectomy (NSM) with immediate breast reconstruction and subsequent prosthetic reconstruction in patients with prior breast radiation therapy (pRT) vs those receiving adjuvant post-mastectomy radiation therapy (PMRT). An IRB-approved, retrospective analysis was performed from 2002 to 2014 to identify NSM patients that underwent pRT or PMRT. A 22-item Likert scale questionnaire was administered by a third party to register patient-reported quality of life...
May 20, 2018: Breast Journal
https://www.readbyqxmd.com/read/29778821/evaluating-mastectomy-skin-flap-necrosis-in-the-extended-breast-reconstruction-risk-assessment-score-for-one-year-prediction-of-prosthetic-reconstruction-outcomes
#8
Nora Hansen, Sasa Espino, Jordan T Blough, Michael M Vu, Neil A Fine, John Ys Kim
BACKGROUND: Rates of mastectomy for breast cancer treatment and immediate reconstruction continue to rise. With increasing scrutiny on outcomes and patient satisfaction, there is an impetus for providers to be more deliberate in deciding appropriate patient selection for breast reconstruction. The Breast Reconstruction Risk Assessment (BRA) Score was developed for prediction of complications after primary prosthetic breast reconstruction, focusing on calculating risk estimations for a variety of complications based on individual patient demographics and perioperative characteristics...
May 17, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29777144/benefits-in-radical-mastectomy-protocol-a-randomized-trial-evaluating-the-use-of-regional-anesthesia
#9
Marcio Matsumoto, Eva M Flores, Pedro P Kimachi, Flavia V Gouveia, Mayra A Kuroki, Alfredo C S D Barros, Marcelo M C Sampaio, Felipe E M Andrade, João Valverde, Eduardo F Abrantes, Claudia M Simões, Rosana L Pagano, Raquel C R Martinez
Surgery is the first-line treatment for early, localized, or operable breast cancer. Regional anesthesia during mastectomy may offer the prevention of postoperative pain. One potential protocol is the combination of serratus anterior plane block (SAM block) with pectoral nerve block I (PECS I), but the results and potential benefits are limited. Our study compared general anesthesia with or without SAM block + PECS I during radical mastectomy with axillary node dissection and breast reconstruction using evaluations of pain, opioid consumption, side effects and serum levels of interleukin (IL)-1beta, IL-6 and IL-10...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776156/realizations-of-highly-heterogeneous-collagen-networks-via-stochastic-reconstruction-for-micromechanical-analysis-of-tumor-cell-invasion
#10
Hanqing Nan, Long Liang, Guo Chen, Liyu Liu, Ruchuan Liu, Yang Jiao
Three-dimensional (3D) collective cell migration in a collagen-based extracellular matrix (ECM) is among one of the most significant topics in developmental biology, cancer progression, tissue regeneration, and immune response. Recent studies have suggested that collagen-fiber mediated force transmission in cellularized ECM plays an important role in stress homeostasis and regulation of collective cellular behaviors. Motivated by the recent in vitro observation that oriented collagen can significantly enhance the penetration of migrating breast cancer cells into dense Matrigel which mimics the intravasation process in vivo [Han et al...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29774974/stiffness-reconstruction-methods-for-mr-elastography
#11
Daniel Fovargue, David Nordsletten, Ralph Sinkus
Assessment of tissue stiffness is desirable for clinicians and researchers, as it is well established that pathophysiological mechanisms often alter the structural properties of tissue. Magnetic resonance elastography (MRE) provides an avenue for measuring tissue stiffness and has a long history of clinical application, including staging liver fibrosis and stratifying breast cancer malignancy. A vital component of MRE consists of the reconstruction algorithms used to derive stiffness from wave-motion images by solving inverse problems...
May 18, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29774315/retrospective-analysis-of-patients-with-synchronous-primary-breast-and-thyroid-carcinoma
#12
İlker Murat Arer, Hakan Yabanoğlu, Murat Kuş, Aydıncan Akdur, Tevfik Avcı
Objective: Breast and thyroid cancers are commonly encountered malignancies. Increased risk of breast cancer in follow-up period of thyroid cancer or vice versa has been reported. However, they have some associations, synchronous presentation of these tumors is rare. We presented 12 patients diagnosed as breast and thyroid cancer and treated at the same time. Materials and Methods: Mastectomy and thyroidectomy were performed in 19 patients at the same time. 7 patients were excluded because of benign thyroid pathology...
April 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29765947/leser-tr%C3%A3-lat-syndrome-in-a-male-with-breast-carcinoma-and-eyelid-basal-cell-carcinoma
#13
Rajiv Garg, Siddharth Madan, Pragya Prakash, Ram Chander, Monisha Choudhary
Purpose: Leser-Trélat syndrome consists of appearance of a solid tumor-like carcinoma breast, colon, or stomach following eruption of multiple seborrheic keratoses (SK) of the skin. We present an unusual and possibly the first case report of Leser-Trélat syndrome in a male patient with a history of mastectomy for breast carcinoma who presented to us with a second malignancy in the form of basal cell carcinoma (BCC) of the lower eyelid. Procedure: A 75-year-old male presented in 2014 with a history of modified radical mastectomy for infiltrating ductal carcinoma of the left breast which was performed 11 years prior to the day of presentation...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29764880/digital-breast-tomosynthesis-plus-synthesised-images-versus-standard-full-field-digital-mammography-in-population-based-screening-tosyma-protocol-of-a-randomised-controlled-trial
#14
Stefanie Weigel, Joachim Gerss, Hans-Werner Hense, Miriam Krischke, Alexander Sommer, Jörg Czwoydzinski, Horst Lenzen, Laura Kerschke, Karin Spieker, Stefanie Dickmaenken, Sonja Baier, Marc Urban, Gerold Hecht, Oliver Heidinger, Joachim Kieschke, Walter Heindel
INTRODUCTION: Development of digital breast tomosynthesis (DBT) provides a technology that generates three-dimensional data sets, thus reducing the pitfalls of overlapping breast tissue. Observational studies suggest that the combination of two-dimensional (2D) digital mammography and DBT increases diagnostic accuracy. However, because of duplicate exposure, this comes at the cost of an augmented radiation dose. This undesired adverse impact can be avoided by using synthesised 2D images reconstructed from the DBT data (s2D)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29762436/preoperative-analysis-of-venous-anatomy-before-deep-inferior-epigastric-perforator-free-flap-breast-reconstruction-using-ferumoxytol-enhanced-magnetic-resonance-angiography
#15
John Dortch, Antonio J Forte, Candice Bolan, Pujan Kandel, Galen Perdikis
BACKGROUND: Venous congestion after deep inferior epigastric artery perforator (DIEP) flap breast reconstruction is a complication that may be partially attributable to variations in venous abdominal wall anatomy. In previous work, we have shown that ferumoxytol may be used as a bloodpool contrast agent to perform high-resolution venous imaging. Our current aim was to use this technology to perform a detailed analysis of the venous anatomy among patients undergoing DIEP flap breast reconstruction...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29761885/immediate-breast-reconstruction-for-women-having-inflammatory-breast-cancer-in-the-united-states
#16
Sameer A Patel, Marilyn Ng, Salvatore M Nardello, Karen Ruth, Richard J Bleicher
Inflammatory breast cancer (IBC) is an aggressive malignancy having a poor prognosis. Traditionally, reconstruction is not offered due to concerns about treatment delay, margin positivity, recurrence, and poor long-term survival. There is a paucity of literature, however, evaluating whether immediate breast reconstruction (IBR) is associated with greater mortality in patients with IBC. A population-based study was conducted via the SEER-Medicare-linked database (1991-2009). Female patients greater than 65 years were reviewed who had mastectomy and reconstruction claims for nonmetastatic IBC...
May 15, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29761322/concurrent-risk-reduction-surgery-in-patients-with-increased-lifetime-risk-for-breast-and-ovarian-cancer-an-analysis-of-the-national-surgical-quality-improvement-program-nsqip-database
#17
Maryam Elmi, Arash Azin, Ahmad Elnahas, David R McCready, Tulin D Cil
BACKGROUND: Patients with genetic susceptibility to breast and ovarian cancer are eligible for risk-reduction surgery. Surgical morbidity of risk-reduction mastectomy (RRM) with concurrent bilateral salpingo-oophorectomy (BSO) is unknown. Outcomes in these patients were compared to patients undergoing RRM without BSO using a large multi-institutional database. METHODS: A retrospective cohort analysis was conducted using the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) 2007-2016 datasets, comparing postoperative morbidity between patients undergoing RRM with patients undergoing RRM with concurrent BSO...
May 14, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29758504/patients-perspectives-and-experiences-concerning-barriers-to-accessing-information-about-bilateral-prophylactic-mastectomy
#18
Rachael Glassey, Moira O'Connor, Angela Ives, Christobel Saunders, kConFab Investigators, Sarah O'Sullivan, Sarah J Hardcastle
PURPOSE: To explore the barriers and experiences of accessing information for women who have received genetic risk assessment/testing results for breast cancer (BC) and are considering a bilateral prophylactic mastectomy (BPM) and, exploring participants' preferences concerning information and support needs. METHODS: A qualitative retrospective study guided by interpretative phenomenological analysis was utilised. Semi-structured interviews were conducted with forty-six women who were either considering BPM or had already undergone the surgery...
May 11, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29753181/weighted-regularized-statistical-shape-space-projection-for-breast-3d-model-reconstruction
#19
Guillermo Ruiz, Eduard Ramon, Jaime García, Federico M Sukno, Miguel A González Ballester
The use of 3D imaging has increased as a practical and useful tool for plastic and aesthetic surgery planning. Specifically, the possibility of representing the patient breast anatomy in a 3D shape and simulate aesthetic or plastic procedures is a great tool for communication between surgeon and patient during surgery planning. For the purpose of obtaining the specific 3D model of the breast of a patient, model-based reconstruction methods can be used. In particular, 3D morphable models (3DMM) are a robust and widely used method to perform 3D reconstruction...
May 2, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29750763/-relationship-between-tamoxifen-and-the-absorption-of-subfascial-autologous-fat-grafts
#20
Alfredo B D Silva, Felipe Haupenthal, André D Morais, Adriana S K Ascenço, Ana P M Sebastião, Manoel A R Cavalcanti, Renato S Freitas
INTRODUCTION: In the lipofilling procedures used in breast reconstruction, there is an unpredictability in the rate of reabsorption of the grafted fat. The objective of this study was to analyze the effect of Tamoxifen, a medication commonly prescribed for patients with breast cancer, as a possible alternative to reduce the rate of autologous fat graft resorption. MATERIALS AND METHODS: The fatty cushion of the inguinal region of 20 female adult Wistar rats was removed and then autografted, using a standard volume of 0...
March 15, 2018: Plastic and Reconstructive Surgery
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