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https://www.readbyqxmd.com/read/28431451/-experience-with-the-hind-foot-relaxation-boot
#1
Hans Zwipp, Michael Borrmann, Eberhard Walter
The goal of this paper is to report our experience with hindfoot fractures using our specially developed boot, with a follow-up of 557 cases. This boot works like the well-known Allgöwer-Röck ortheses (ARO), but is a hybrid between a boot and an orthesis. It allows full weightbearing without using crutches and completely protects an acutely operated hind foot fracture, hind foot arthrodesis or a hind foot fracture which is suitable for conservative treatment. In its first generation, this boot was custom made and used in 408 cases, from March 1999 to February 2011...
April 21, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28431324/achievable-separation-performance-and-analysis-time-in-current-liquid-chromatographic-practice-for-monoclonal-antibody-separations
#2
Szabolcs Fekete, Jean-Luc Veuthey, Davy Guillarme
The separation performance of a chromatographic system is often described in terms of column efficiency and peak capacity. Thanks to the new developments in column technology over the past few years, the achievable peak capacity drastically improved and the analysis time can be significantly shortened. Indeed, highly efficient wide-pore reversed-phase (RPLC) materials packed with small fully porous and superficially porous particles can be successfully used for the analytical characterization of therapeutic proteins...
April 12, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28431303/circular-shape-constrained-fuzzy-clustering-ciscfc-for-nucleus-segmentation-in-pap-smear-images
#3
Ratna Saha, Mariusz Bajger, Gobert Lee
Accurate detection and segmentation of cell nucleus is the precursor step towards computer aided analysis of Pap smear images. This is a challenging and complex task due to degree of overlap, inconsistent staining and poor contrast. In this paper, a novel nucleus segmentation method is proposed by incorporating a circular shape function in fuzzy clustering. The proposed method was evaluated quantitatively and qualitatively using the Overlapping Cervical Cytology Image Segmentation Challenge - ISBI 2014 challenge dataset comprised of 945 overlapping Pap smear images...
April 14, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28431277/endocrine-disruption-by-environmental-gestagens-in-amphibians-a-short-review-supported-by-new-in%C3%A2-vitro-data-using-gonads-of-xenopus-laevis
#4
REVIEW
Andrea Ziková, Claudia Lorenz, Frauke Hoffmann, Wibke Kleiner, Ilka Lutz, Matthias Stöck, Werner Kloas
Endocrine disruption caused by various anthropogenic compounds is of persisting concern, especially for aquatic wildlife, because surface waters are the main sink of these so-called endocrine disruptors (ED). In the past, research focused on (anti)estrogenic, (anti)androgenic, and (anti)thyroidal substances, affecting primarily reproduction and development in vertebrates; however, other endocrine systems might be also targeted by ED. Environmental gestagens, including natural progestogens (e.g. progesterone (P4)) and synthetic progestins used for contraception, are supposed to affect vertebrate reproduction via progesterone receptors...
April 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28430248/accurate-determination-of-dielectric-permittivity-of-polymers-from-75%C3%A2-%C3%A2-ghz-to-1-6%C3%A2-%C3%A2-thz-using-both-s-parameters-and-transmission-spectroscopy
#5
Tianying Chang, Xiansheng Zhang, Xiaoxuan Zhang, Hong-Liang Cui
Interactions of terahertz (THz) electromagnetic radiation with polymer materials have been studied recently with increasing depth and breadth, for purposes of both using polymers in fabricating THz optical components such as lenses, waveplates, waveguides, and sample holders/containers, and employing THz spectral imaging as a new tool for nondestructive testing of polymer composite structures. Either endeavor cannot even begin without a quantitative knowledge of the complex dielectric permittivity, i.e., the propagation and attenuation properties of such polymers in the requisite wave band...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430239/research-on-intelligent-algorithms-for-amplitude-optimization-of-wavefront-shaping
#6
Qi Feng, Bin Zhang, Zhipeng Liu, Chengyou Lin, Yingchun Ding
This paper demonstrates further research on intelligent algorithms of binary amplitude optimization for wavefront shaping by numerical simulations. A better fitness function of the genetic algorithm (GA) has been presented after a comparative analysis of enhancement. With this new discriminant, we have achieved a relative enhancement of 0.225, which is higher than the theoretical value (0.159). In addition, we have also proposed a kind of modified particle swarm optimization algorithm (PSO), which has a higher enhancement than the unmodified PSO and a faster convergence speed than the GA...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28430146/a-new-method-for-single-epoch-ambiguity-resolution-with-indoor-pseudolite-positioning
#7
Xin Li, Peng Zhang, Jiming Guo, Jinling Wang, Weining Qiu
Ambiguity resolution (AR) is crucial for high-precision indoor pseudolite positioning. Due to the existing characteristics of the pseudolite positioning system, such as the geometry structure of the stationary pseudolite which is consistently invariant, the indoor signal is easy to interrupt and the first order linear truncation error cannot be ignored, and a new AR method based on the idea of the ambiguity function method (AFM) is proposed in this paper. The proposed method is a single-epoch and nonlinear method that is especially well-suited for indoor pseudolite positioning...
April 21, 2017: Sensors
https://www.readbyqxmd.com/read/28430133/nuclear-molecular-imaging-strategies-in-immune-checkpoint-inhibitor-therapy
#8
REVIEW
Kasper F Guldbrandsen, Helle W Hendel, Seppo W Langer, Barbara M Fischer
Immune checkpoint inhibitor therapy (ICT) is a new treatment strategy developed for the treatment of cancer. ICT inhibits pathways known to downregulate the innate immune response to cancer cells. These drugs have been shown to be effective in the treatment of a variety of cancers, including metastatic melanoma and lung cancer. Challenges in response evaluation of patients in ICT have risen as immune related side effects and immune cell infiltration may be confused with progressive disease. Furthermore, the timing of the evaluation scan may be challenged by relatively slow responses...
April 21, 2017: Diagnostics
https://www.readbyqxmd.com/read/28430076/on-using-distributional-analysis-techniques-for-determining-the-onset-of-the-influence-of-experimental-variables
#9
Eyal M Reingold, Heather Sheridan
Much of the investigation of eye-movement control in visual cognition has focused on the influence of experimental variables on mean fixation durations. In the present paper we explored the convergence between two distributional analysis techniques that were recently introduced in this domain. First, Staub, White, Drieghe, Hollway and Rayner, (2010) proposed fitting the ex-Gaussian distribution to individual participants' data in order to ascertain whether a variable has a rapid or a slow influence on fixation durations...
April 21, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28429997/attitudes-toward-cognitive-enhancer-use-among-new-zealand-tertiary-students
#10
Sanyogita Sanya Ram, Safeera Hussainy, Marcus Henning, Kay Stewart, Maree Jensen, Bruce Russell
BACKGROUND: Cognitive enhancement is the use of prescription stimulant medicines by healthy individuals for nonmedical use in academic settings. Commonly used cognitive enhancers (CEs) include methylphenidate, amphetamines, and modafinil. To understand the motivation to use CEs, it is important to look beyond prevalence and explore the extent to which attitudes, beliefs, and intentions predict the decision to use CEs. OBJECTIVE: The study aimed to investigate what factors explain the decision to use CEs among tertiary students in New Zealand, using the Theory of Planned Behaviour (TPB)...
April 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28429929/flexible-paper-like-free-standing-electrodes-by-anchoring-ultrafine-sns2-nanocrystals-on-graphene-nanoribbons-for-high-performance-sodium-ion-batteries
#11
Yang Liu, Yongzhen Yang, Xuzhen Wang, Yanfeng Dong, Yongchao Tang, Zhengfa Yu, Zongbin Zhao, Jieshan Qiu
Ultrafine SnS2 nanocrystals/reduced graphene oxide nanoribbon paper (SnS2/RGONRP) has been created by a well-designed process including in situ reduction, evaporation induced self-assembly and sulfuration. The as formed SnS2 nanocrystals possess an average diameter of 2.3 nm and disperse on the surface of RGONRs uniformly. The strong capillary force formed during evaporation leads to a compact assembly of RGONRs to give flexible paper structure with high density of 0.94 g cm-3. The as-prepared SnS2/RGONRP composite could be directly used as free-standing electrode for sodium ion batteries...
April 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28429867/health-related-quality-of-life-questionnaires-in-individuals-with-haemophilia-a-systematic-review-of-their-measurement-properties
#12
REVIEW
P F Limperg, C B Terwee, N L Young, V E Price, S C Gouw, M Peters, M A Grootenhuis, V Blanchette, L Haverman
BACKGROUND: The evaluation of health related quality of life (HRQOL) is essential for a full assessment of the influence of an illness on patients' lives. The aim of this paper is to critically appraise and compare the measurement properties of HRQOL questionnaires studied in haemophilia. METHODS: Bibliographic databases (Embase, Medline, Cinahl and PsycInfo) were searched for articles evaluating measurement properties of HRQOL questionnaires in haemophilia. Articles were excluded that did not report HRQOL measurement properties, or when <50% of the study population had haemophilia...
April 21, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28429683/biokinetics-of-yttrium-and-comparison-with-its-geochemical-twin-holmium
#13
Richard Wayne Leggett
The transition metal yttrium (Y, atomic number 39) is chemically similar to elements in the lanthanide family (atomic numbers 57-71) and is found with the lanthanides in rare earth ores. Yttrium and the lanthanide holmium are referred to as geochemical twins because they generally show little fractionation from metamorphic or weathering processes, due to their closely similar chemical properties and nearly identical ionic radii. Extensive measurements on rocks, soils, and meteorites indicate that the Y/Ho mass concentration ratio rarely falls far from the so-called chondritic or solar system ratio of ~26...
April 21, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28429589/inhibition-of-zero-drift-in-the-perovskite-based-photodetector-devices-via-pcbm-doping
#14
Yintao Liu, Renxu Jia, Yucheng Wang, Ziyang Hu, Yuming Zhang, Tiqiang Pang, Yuejin Zhu, Suzhen Luan
The zero drift can severely deteriorate the stability of light-dark current ratio, detectivity and responsivity of the photodetectors. In this paper, the effects of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) doped perovskite based photodetector device on the inhibition of zero drift under dark state are discusses. Two kinds of photodetectors (Au/CH3NH3PbIxCl3-x/Au and Au/CH3NH3PbIxCl3-x:PCBM/Au) are prepared, and the materials and photodetector devices are measured by scanning electron microscope, X-ray diffraction, photoluminescence, ultra-violet absorption spectra, current-voltage and current-time...
April 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28429462/kinship-nomadism-and-humanitarian-aid-among-somalis-in-ethiopia
#15
Lauren Carruth
This paper draws on extended ethnographic and health policy research in eastern Ethiopia to reconsider kinship and nomadism among Somalis, as both of these cultural features transform in the contexts of recurrent humanitarian crises and episodic relief operations. The emergence and importance of new patterns of travel and migration among Somalis in Ethiopia reveal significant changes in the configurations and enactments of Somali kinship, on which many Somalis' mobility depends. Conversely, an analysis of Somalis' dynamic sub-clan groupings and geographically dispersed kinship networks also highlights emergent patterns of mobility and migration that enable access to training opportunities and employment with relief organisations, as well as to distributions of humanitarian aid...
April 21, 2017: Disasters
https://www.readbyqxmd.com/read/28428991/a-room-temperature-phosphorescent-polymer-film-containing-a-molecular-web-based-on-one-dimensional-chiral-stacking-of-a-simple-luminophore
#16
Kyohei Yoshida, Yutaka Kuwahara, Koji Miyamoto, Seiya Nakashima, Hirokuni Jintoku, Makoto Takafuji, Hirotaka Ihara
We propose a new approach for a totally organic, room-temperature phosphorescent system with a lifetime on the order of milliseconds, which is achieved by promotion of the one-dimensional chiral stacking of a simple, small fluorophore in a solution state. The versatility of this system is highlighted by its good applicability to the fabrication of a phosphorescent polymer film. This paper demonstrates the first example of a room-temperature phosphorescent polymer film prepared with our methodology.
April 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28428837/large-is-required-for-normal-astrocyte-migration-and-retinal-vasculature-development
#17
Min Zhou, Herui Wang, Hui Ren, Rui Jiang, Chi Zhang, Xiaohui Wu, Gezhi Xu
BACKGROUND: Persistent fetal vasculature (PFV) is a congenital developmental anomaly of the eye that accounts for about 5% of childhood blindness. The molecular mechanism of PFV remains unclear. As a glycosyltransferase of α-dystroglycan, LARGE mutations have been found in congenital muscular dystrophy patients with brain abnormalities. Spontaneous Large mutant mice displayed similar symptoms of human muscle-eye-brain disorders. However, the detailed roles of Large in ocular vasculature development still need to be uncovered...
2017: Cell & Bioscience
https://www.readbyqxmd.com/read/28428674/comparison-of-clinical-and-radiological-parameters-at-knee-osteoarthritis
#18
Adnana Talic-Tanovic, Zoran Hadziahmetovic, Ivanka Madjar-Simic, Adnan Papovic
INTRODUCTION: Osteoarthritis (OA) or arthrosis represents an inflammatory disease of joints that develops as a result of interaction of mechanical and biological parameters. With disease development, degenerative changes on joint cartilage can be noticeable that affect and cause pathological changes on other parts of a joint resulting in pain and dysfunction of a joint. A. E. Garrod in 1907 described osteoarthritis as a special clinical entity and separated it from a rheumatoid arthritis...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28428623/paper-strip-embedded-graphene-quantum-dots-a-screening-device-with-a-smartphone-readout
#19
Ruslan Álvarez-Diduk, Jahir Orozco, Arben Merkoçi
Simple, inexpensive and rapid sensing systems are very demanded for a myriad of uses. Intrinsic properties of emerging paper-based analytical devices have demonstrated considerable potential to fulfill such demand. This work reports an easy-to-use, low cost, and disposable paper-based sensing device for rapid chemical screening with a smartphone readout. The device comprises luminescent graphene quantum dots (GQDs) sensing probes embedded into a nitrocellulose matrix where the resonance energy transfer phenomenon seems to be the sensing mechanism...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428043/effects-of-bone-marrow-on-the-microenvironment-of-the-human-pancreatic-islet-a-protein-profile-approach
#20
Joseph William Kim, Souriya Vang, John Luo, William Newton, Luguang Luo
Stem cells are a new therapeutic modality that may support the viability and function of human organs and tissue. Our previous studies have revealed that human allogeneic bone marrow (BM) sustains pancreatic β cell function and survival. This paper examines whether BM creates a microenvironment that supports human pancreatic islets in vitro by evaluating 107 proteins in culture media from BM, islet, and islet/bone marrow (IB) with mass spectrometry. Proteins were considered up- or down-regulated if p-values < 0...
April 17, 2017: Molecular and Cellular Endocrinology
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