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https://www.readbyqxmd.com/read/28725791/quality-improvement-intervention-for-reduction-of-redundant-testing
#1
Alan M Ducatman, Danyel H Tacker, Barbara S Ducatman, Dustin Long, Peter L Perrotta, Hannah Lawther, Kelly Pennington, Owen Lander, Mary Warden, Conard Failinger, Kevin Halbritter, Ronald Pellegrino, Marney Treese, Jeffrey A Stead, Eric Glass, Lauren Cianciaruso, Konrad C Nau
Laboratory data are critical to analyzing and improving clinical quality. In the setting of residual use of creatine kinase M and B isoenzyme testing for myocardial infarction, we assessed disease outcomes of discordant creatine kinase M and B isoenzyme +/troponin I (-) test pairs in order to address anticipated clinician concerns about potential loss of case-finding sensitivity following proposed discontinuation of routine creatine kinase and creatine kinase M and B isoenzyme testing. Time-sequenced interventions were introduced...
January 2017: Acad Pathol
https://www.readbyqxmd.com/read/28725606/drugs-for-the-overactive-bladder-are-there-differences-in-persistence-and-compliance
#2
EDITORIAL
Karl-Erik Andersson
No abstract text is available yet for this article.
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28721024/cost-of-medication-adherence-and-persistence-in-type-2-diabetes-mellitus-a-literature-review
#3
REVIEW
Tessa Kennedy-Martin, Kristina S Boye, Xiaomei Peng
PURPOSE: To explore published evidence on health care costs associated with adherence or persistence to antidiabetes medications in adults with type 2 diabetes mellitus (T2DM). METHODS: Primary research studies published between January 2006 and December 2015 on compliance, adherence, or persistence and treatment in patients with T2DM that document a link with health care costs were identified through literature searches in bibliographic databases and 2015 abstract books for relevant DM congresses...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28709417/putting-women-at-the-center-a-review-of-indian-policy-to-address-person-centered-care-in-maternal-and-newborn-health-family-planning-and-abortion
#4
Aradhana Srivastava, Devaki Singh, Dominic Montagu, Sanghita Bhattacharyya
BACKGROUND: Person-centered care is a critical component of quality care, essential to enable treatment adherence, and maximize health outcomes. Improving the quality of health services is a key strategy to achieve the new global target of zero preventable maternal deaths by 2030. Recognizing this, the Government of India has in the last decade initiated a number of strategies to address quality of care in health and family welfare services. METHODS: We conducted a policy review of quality improvement strategies in India from 2005 to 15, covering three critical areas- maternal and newborn health, family planning, and abortion (MNHFP + A)...
July 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28689843/nonpharmacologic-therapy-for-severe-persistent-asthma
#5
Chase Hall, Linda Nici, Shweta Sood, Richard ZuWallack, Mario Castro
The treatment of asthma largely depends on guideline-based pharmacologic therapies. However, nonpharmacologic therapies for asthma such as pulmonary rehabilitation, focused breathing techniques, and bronchial thermoplasty have an important, yet underappreciated, role. Structured pulmonary rehabilitation programs can reduce dyspnea and increase cardiopulmonary fitness. The educational component of these programs can ensure that therapies are being used appropriately, increase compliance, and decrease health care utilization...
July 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28683846/beyond-the-pill-new-medication-delivery-options-for-adhd
#6
Andrew J Cutler, Gregory W Mattingly
Successful treatment of pediatric disorders has necessitated the development of alternative medication formulations, as children may prefer alternative dosage forms to tablets or capsules. This is especially true for attention-deficit/hyperactivity disorder (ADHD), which is one of the most common chronic pediatric conditions and often involves children with a variety of overlapping physical, psychological, or neurodevelopmental disorders. A special challenge for developing alternative dosage forms for ADHD treatment is the incorporation of a once-daily long-acting formulation...
July 7, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28681501/systematic-development-of-esthetics-and-function-in-a-young-patient-with-maxillary-dental-aplasia
#7
D Edelhoff, O Prandtner, R Saeidi Pour, A Wichelhaus, A Liebermann
OBJECTIVES: Full-arch rehabilitations in young patients suffering from dental agenesis should compensate for the reduced vertical dimension of occlusion and restore both esthetics and function at minimal biological cost. This requires precise planning and maximum patient compliance during the preprosthetic phase. The pretreatment period with tooth-colored splints promotes a predictable outcome of the final restorations. Clinical considerations: Thanks to better restorative materials and adhesive techniques and increased knowledge of how to preserve sound tooth structures, prosthetic dentistry has increasingly turned toward minimally invasive procedures...
July 6, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28639853/persistent-rule-following-in-the-face-of-reversed-reinforcement-contingencies-the-differential-impact-of-direct-versus-derived-rules
#8
Colin Harte, Yvonne Barnes-Holmes, Dermot Barnes-Holmes, Ciara McEnteggart
Rule-governed behavior and its role in generating insensitivity to direct contingencies of reinforcement have been implicated in human psychological suffering. In addition, the human capacity to engage in derived relational responding has also been used to explain specific human maladaptive behaviors, such as irrational fears. To date, however, very little research has attempted to integrate research on contingency insensitivity and derived relations. The current work sought to fill this gap. Across two experiments, participants received either a direct rule (Direct Rule Condition) or a rule that involved a novel derived relational response (Derived Rule Condition)...
June 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/28612061/management-of-vesicoureteral-reflux-in-neurogenic-bladder
#9
REVIEW
Charlotte Q Wu, Israel Franco
Vesicoureteral reflux (VUR) is a significant risk factor for pyelonephritis and renal scarring. VUR can occur through a defective ureterovesical junction (UVJ) or an overwhelmed normal UVJ mechanism such as in bladder dysfunction of congenital, acquired, or behavioral etiology. There are numerous causes for the development of a neurogenic bladder from spinal dysraphisms to spinal cord trauma and even centrally based abnormalities in children with apparently normal motor function (inappropriately termed nonneurogenic neurogenic bladder)...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28611949/pseudomalabsorption-of-levothyroxine-a-challenge-for-the-endocrinologist-in-the-treatment-of-hypothyroidism
#10
Nancy Van Wilder, Bert Bravenboer, Sarah Herremans, Nathalie Vanderbruggen, Brigitte Velkeniers
BACKGROUND: Hypothyroidism due to non-compliance with levothyroxine therapy (pseudomalabsorption) is rare. The diagnosis is considered in patients with persistent severe hypothyroidism despite treatment with large doses of levothyroxine. Intestinal malabsorption, drug and dietary interference with levothyroxine absorption and nephrotic syndrome should be excluded. The diagnosis of pseudomalabsorption can be demonstrated by using "an oral 1,000 µg of levothyroxine test" showing a rapid decrease in thyroid-stimulating hormone and increase in thyroxine...
February 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/28590377/brace-success-is-related-to-curve-type-in-patients-with-adolescent-idiopathic-scoliosis
#11
Rachel M Thompson, Elizabeth W Hubbard, Chan-Hee Jo, Donald Virostek, Lori A Karol
BACKGROUND: Curve magnitude and skeletal maturity are important factors in determining the efficacy of bracing for the treatment of adolescent idiopathic scoliosis, but curve morphology may also affect brace success. The purpose of this study was to determine the influence of curve morphology on the response to bracing with a thoracolumbosacral orthosis (TLSO). METHODS: A retrospective review of patients managed with an orthosis for the treatment of adolescent idiopathic scoliosis who were prospectively enrolled at the initiation of brace wear and followed through completion of bracing or surgery was performed...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28588883/compliance-with-evidence-based-multidisciplinary-guidelines-on-perihilar-cholangiocarcinoma
#12
Robert Js Coelen, Joost Huiskens, Pim B Olthof, Eva Roos, Jimme K Wiggers, Annuska Schoorlemmer, Otto M van Delden, Heinz-Josef Klümpen, Erik Aj Rauws, Thomas M van Gulik
BACKGROUND: Discrepancies are often noted between management of perihilar cholangiocarcinoma (PHC) in regional hospitals and the eventual treatment plan in specialized centers. OBJECTIVE: The objective of this article is to evaluate whether regional centers adhere to guideline recommendations following implementation in 2013. METHODS: Data were analyzed from all consecutive patients with suspected PHC referred to our academic center between June 2013 and December 2015...
June 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28572736/asthma-like-airway-inflammation-and-responses-in-a-rat-model-of-atopic-dermatitis-induced-by-neonatal-capsaicin-treatment
#13
Rafael Taeho Han, Sewon Kim, Kyungmin Choi, Hyeonseok Jwa, JaeHee Lee, Hye Young Kim, Hee Jin Kim, Hang-Rae Kim, Seung Keun Back, Heung Sik Na
Recent studies have shown that approximately 70% of patients with severe atopic dermatitis (AD) develop asthma. Development of AD in infancy and subsequent other atopic diseases such as asthma in childhood is referred to as atopic march. However, a causal link between the diseases of atopic march has remained largely unaddressed, possibly due to lack of a proper animal model. Recently, we developed an AD rat model showing chronically relapsing dermatitis and scratching behaviors induced by neonatal capsaicin treatment...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/28571190/the-study-of-different-clinical-pattern-of-diabetic-ketoacidosis-and-common-precipitating-events-and-independent-mortality-factors
#14
M G Mahesh, Rajendra Prasad Shivaswamy, Bj Subhash Chandra, Sajid Syed
INTRODUCTION: Diabetic Ketoacidosis (DKA) is an important cause of morbidity and mortality among diabetic patients in spite of major advances in the pathogenesis and more standardized diagnosis and treatment. AIM: To find out the different patterns of clinical presentations, common precipitating factors and independent mortality factors in DKA. MATERIALS AND METHODS: This study was conducted in a tertiary care hospital, Mysuru on 110 patients from November 2007 to October 2009...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28560786/medication-compliance-and-clinical-outcomes-of-fixed-dose-combinations-vs-free-combinations-of-an-angiotensin-ii-receptor-blocker-and-a-calcium-channel-blocker-in-hypertension-treatment
#15
Ying-Chang Tung, Yu-Chang Huang, Lung-Sheng Wu, Chee-Jen Chang, Pao-Hsien Chu
Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens...
May 30, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28557049/left-dorsolateral-prefrontal-cortex-rtms-in-alleviating-mtbi-related-headaches-and-depressive-symptoms
#16
Albert Leung, Valerie Metzger-Smith, Yifan He, James Cordero, Brandon Ehlert, David Song, Lisa Lin, Golshan Shahrokh, Alice Tsai, Michael Vaninetti, Thomas Rutledge, Greg Polston, Robert Sheu, Roland Lee
OBJECTIVE: Persistent mild traumatic brain injury related headache (MTBI-HA) represents a neuropathic pain state. This study tested the hypothesis that repetitive transcranial magnetic stimulation (rTMS) at the left prefrontal cortex can alleviate MTBI-HA and associated neuropsychological dysfunctions. METHODS AND MATERIALS: Veterans with MTBI-HA were randomized to receive four sessions of either real (REAL group) or sham (SHAM group) high frequency rTMS delivered at 10 Hz, 80% of resting motor threshold and 2000 pulses per session at >24 and <72 hours apart...
May 30, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28551922/-the-treatment-of-hypertension-by-fixed-drug-combinations-in-patients-hospitalized-at-the-department-of-medicine
#17
Avishay Elis, Amit Akirov
AIMS: To determine the rate of hypertensive patients hospitalized at the department of medicine who are treated or are candidates for fixed dose drug combinations. BACKGROUND: Despite the high prevalence of hypertension and rates of awareness, The number of patients treated and well controlled are low. The main reasons for not achieving blood pressure target levels are compliance and persistence with drug therapy. METHODS: A multicenter, retrospective records review was conducted of hypertensive patients hospitalized at departments of medicine during 2014...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28523865/the-interstitial-carbon-of-the-nitrogenase-femo-cofactor-is-far-better-stabilized-than-previously-assumed
#18
Jörg Grunenberg
The first quantum-mechanical calculations of all relevant potential constants in both the iron-molybdenum cofactor and the iron-vanadium cofactor of nitrogenase suggest that the carbide is bound to the center of the enzyme much more strongly than hitherto assumed. Previous studies seemed to indicate a dummy function of the interstitial carbon, with a weak force constant (ca. 0.32 N cm(-1) ). Our new investigations confirm a different picture: the central carbon atom binds the iron-sulfur cluster through six covalent C-Fe bonds...
June 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28509730/american-college-of-critical-care-medicine-clinical-practice-parameters-for-hemodynamic-support-of-pediatric-and-neonatal-septic-shock
#19
Alan L Davis, Joseph A Carcillo, Rajesh K Aneja, Andreas J Deymann, John C Lin, Trung C Nguyen, Regina S Okhuysen-Cawley, Monica S Relvas, Ranna A Rozenfeld, Peter W Skippen, Bonnie J Stojadinovic, Eric A Williams, Tim S Yeh, Fran Balamuth, Joe Brierley, Allan R de Caen, Ira M Cheifetz, Karen Choong, Edward Conway, Timothy Cornell, Allan Doctor, Marc-Andre Dugas, Jonathan D Feldman, Julie C Fitzgerald, Heidi R Flori, James D Fortenberry, Ana Lia Graciano, Bruce M Greenwald, Mark W Hall, Yong Yun Han, Lynn J Hernan, Jose E Irazuzta, Elizabeth Iselin, Elise W van der Jagt, Howard E Jeffries, Saraswati Kache, Chhavi Katyal, Niranjan Tex Kissoon, Alexander A Kon, Martha C Kutko, Graeme MacLaren, Timothy Maul, Renuka Mehta, Fola Odetola, Kristine Parbuoni, Raina Paul, Mark J Peters, Suchitra Ranjit, Karin E Reuter-Rice, Eduardo J Schnitzler, Halden F Scott, Adalberto Torres, Jacki Weingarten-Abrams, Scott L Weiss, Jerry J Zimmerman, Aaron L Zuckerberg
OBJECTIVES: The American College of Critical Care Medicine provided 2002 and 2007 guidelines for hemodynamic support of newborn and pediatric septic shock. Provide the 2014 update of the 2007 American College of Critical Care Medicine "Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shock." DESIGN: Society of Critical Care Medicine members were identified from general solicitation at Society of Critical Care Medicine Educational and Scientific Symposia (2006-2014)...
June 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28504048/the-penn-state-heart-assistant-a-pilot-study-of-a-web-based-intervention-to-improve-self-care-of-heart-failure-patients
#20
Tom Lloyd, Harleah Buck, Andrew Foy, Sara Black, Antony Pinter, Rosanne Pogash, Bobby Eismann, Eric Balaban, John Chan, Allen Kunselman, Joshua Smyth, John Boehmer
The Penn State Heart Assistant, a web-based, tablet computer-accessed, secure application was developed to conduct a proof of concept test, targeting patient self-care activities of heart failure patients including daily medication adherence, weight monitoring, and aerobic activity. Patients (n = 12) used the tablet computer-accessed program for 30 days-recording their information and viewing a short educational video. Linear random coefficient models assessed the relationship between weight and time and exercise and time...
May 1, 2017: Health Informatics Journal
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