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https://www.readbyqxmd.com/read/29161704/long-term-renal-and-cardiac-outcomes-after-stenting-in-patients-with-resistant-hypertension-and-atherosclerotic-renal-artery-stenosis
#1
Cristiana Catena, GianLuca Colussi, Gabriele Brosolo, Nicolas Verheyen, Marileda Novello, Nicole Bertin, Alessandro Cavarape, Leonardo A Sechi
BACKGROUND/AIMS: Atherosclerotic renal artery stenosis (ARAS) is frequently detected in patients with resistant hypertension (RHTN), but the evidence supporting the utility of renal revascularization in these patients is limited. This prospective, observational study investigates the outcomes of renal stenting in patients with RHTN and hemodynamically significant ARAS. METHODS: Fifty-four patients with RHTN were selected because of angiographic evidence of ARAS >70% and were followed for 4 years after renal stenting...
November 21, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29161219/a-case-study-perspective-the-experiences-of-young-persons-testifying-to-child-sexual-exploitation-in-british-criminal-court
#2
Elizabeth Ahern, Marlene Kowalski, Michael E Lamb
Three young persons who gave evidence about child sexual exploitation in criminal court using various testimonial supports were interviewed about their testimony experiences. The witnesses reported that they felt extreme pressure to remember events accurately and cared greatly about being believed. None reported their own coping strategies to alleviate stress and took comfort breaks only after they cried on the stand. Defense attorney questions were reportedly repetitive, rapid, confusing, and focused on secondary content rather than the central criminal acts...
November 21, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29161170/examining-the-implementation-of-collaborative-competencies-in-a-critical-care-setting-key-challenges-for-enacting-competency-based-education
#3
Joanne Goldman, Simon Kitto, Scott Reeves
Interprofessional collaboration is recognised as an important factor in improving patient care in intensive care units (ICUs). Competency frameworks, and more specifically interprofessional competency frameworks, are a key strategy being used to support the development of attitudes, knowledge, skills, and behaviours needed for an interprofessional approach to care. However, evidence for the application of competencies is limited. This study aimed to extend our empirically based understanding of the significance of interprofessional competencies to actual clinical practice in an ICU...
November 21, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29161129/research-validity-of-measurements-when-reusing-icare-probes
#4
Michelle S Lee, Brad Barnett, Jing Tian, Scott McCabe, Eric L Singman
BACKGROUND: It has been reported that reusing Icare tonometer probes may not pose a considerable risk of transmission of infection, thereby supporting this practice under extraordinary circumstances, such as mass glaucoma screenings in developing countries. The present study sought to determine whether reusing the probes reduced the validity of pressure readings. METHODS: Thousands of measurements were made with the same Icare probe on a purpose-built calibration device...
November 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/29160723/automation-of-a-dosing-disc-capsule-filler-from-the-perspective-of-reliability-and-safety
#5
Bernhard Wagner, Thomas Brinz, Stephanie Otterbach, Johannes Khinast
The aim of this paper is to explore the possibility to develop an automatically adjustable, reliable and safe capsule filling operation. Process parameters that are critical for the tamping pin process were reviewed based on the literature and via experiment. Dosing disc height, powder bed height, machine speed, pressure on the tamping pin and immersion depth were reviewed. Two investigations were performed on a GKF 702. In the first one, the powder feed rate onto the dosing disc was examined and modified. A distance sensor with a PID controller enabled a constant powder bed level with an online changeable set point...
November 21, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/29160152/effect-of-wetted-surface-area-on-friction-pressure-wave-and-total-drag-of-a-kayak
#6
Beatriz B Gomes, Leandro Machado, Nuno V Ramos, Filipe A V Conceição, Ross H Sanders, Mário A P Vaz, João Paulo Vilas-Boas, David R Pendergast
Using theoretical principles, the components of drag (friction DF, pressure DPR and wave DW) of a single-seat kayak were analysed. The purpose was to examine the effect of changes in wetted surface area due to changes in kayaker's weight and the relative contribution of DF, DPR and DW to the total passive drag as function of velocity. The total passive drag values were based on experimental data collected in a single-seat kayak. Three different kayaker simulated weights were tested - 65, 75 and 85 kg. DF was the drag component that contributed the greatest percentage (between 60 and 68% at 5...
November 21, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29159682/physiological-and-biomechanical-responses-of-highly-trained-distance-runners-to-lower-body-positive-pressure-treadmill-running
#7
Kyle R Barnes, Jessica N Janecke
BACKGROUND: As a way to train at faster running speeds, add training volume, prevent injury, or rehabilitate after an injury, lower-body positive pressure treadmills (LBPPT) have become increasingly commonplace among athletes. However, there are conflicting evidence and a paucity of data describing the physiological and biomechanical responses to LBPPT running in highly trained or elite caliber runners at the running speeds they habitually train at, which are considerably faster than those of recreational runners...
November 21, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/29158899/diaphragm-thickening-fraction-to-predict-weaning-a-prospective-exploratory-study
#8
Sujay Samanta, Ratender Kumar Singh, Arvind K Baronia, Banani Poddar, Afzal Azim, Mohan Gurjar
Background: Diaphragm ultrasound (DUS) is a well-established point of care modality for assessment of dimensional and functional aspects of the diaphragm. Amongst various measures, diaphragmatic thickening fraction (DTf) is more comprehensive. However, there is still uncertainty about its capability to predict weaning from mechanical ventilation (MV). The present prospective observational exploratory study assessed the diaphragm at variable negative pressure triggers (NPTs) with US to predict weaning in ICU patients...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/29158679/treatment-of-pulmonary-hypertension-with-left-heart-disease-a-concise-review
#9
REVIEW
Anish Desai, Shilpa A Desouza
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥ 25 mmHg, as determined by right heart catheterization. Pulmonary arterial hypertension (PAH) can no longer be considered an orphan disease given the increase in awareness and availability of new drugs. PH carries with it a dismal prognosis and leads to significant morbidity and mortality. Symptoms can range from dyspnea, fatigue and chest pain to right ventricular failure and death. PH is divided into five groups by the World Health Organization (WHO), based on etiology...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29158565/convergent-evolution-of-plant-and-animal-embryo-defences-by-hyperstable-non-digestible-storage-proteins
#10
María Yanina Pasquevich, Marcos Sebastián Dreon, Jian-Wen Qiu, Huawei Mu, Horacio Heras
Plants have evolved sophisticated embryo defences by kinetically-stable non-digestible storage proteins that lower the nutritional value of seeds, a strategy that have not been reported in animals. To further understand antinutritive defences in animals, we analysed PmPV1, massively accumulated in the eggs of the gastropod Pomacea maculata, focusing on how its structure and structural stability features affected its capacity to withstand passage through predator guts. The native protein withstands >50 min boiling and resists the denaturing detergent sodium dodecyl sulphate (SDS), indicating an unusually high structural stability (i...
November 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29158357/evidence-for-a-role-of-vascular-endothelium-in-the-control-of-arterial-wall-viscosity-in-humans
#11
Frederic Roca, Michele Iacob, Isabelle Remy-Jouet, Jeremy Bellien, Robinson Joannides
Arterial wall viscosity (AWV) is a major cause of energy dissipation along the arterial tree. Its determinants remain controversial but an active endothelial regulation has been suggested. Our objective was to assess in humans the physiological role of endothelium-derived nitric oxide (NO), epoxyeicosatrienoic acids and the effect of modulating smooth muscle tone in the regulation of AWV. We simultaneously measured radial artery diameter, wall thickness, and arterial pressure in healthy volunteers during the local infusion of inhibitors of NO-synthase (N(G)-monomethyl-l-arginine), epoxyeicosatrienoic acids synthesis by cytochrome P450 (fluconazole), the epoxyeicosatrienoic acids cellular targets calcium-activated potassium channels (tetraethylammonium), alone and in combination...
November 20, 2017: Hypertension
https://www.readbyqxmd.com/read/29158181/effects-of-noninvasive-ventilation-with-bilevel-positive-airway-pressure-on-exercise-tolerance-and-dyspnea-in-heart-failure-patients
#12
Mansueto Gomes Neto, Laís Fernanda Gama Duarte, Erenaldo de Sousa Rodrigues-Jr, Hugo Souza Bittencourt, Noélia Gonçalves Dos Santos, Bruno Costa David, Eugênia da Silva Lima, Helena França Correia Dos Reis
BACKGROUND: Heart failure (HF) is a syndrome that results in inadequate blood supply, leading to a number of structural and functional changes. Noninvasive ventilatory support (NIVS) is used as an adjuvant treatment to improve the functional capacity of these patients. OBJECTIVE: To investigate the effect of NIVS with bilevel positive airway pressure ventilation (BiPAP) on exercise tolerance and dyspnea in HF patients. METHODS: Forty patients with New York Heart Association class I/II/III HF were randomly assigned either to a NIVS group (n=20) or a control group (n=20)...
November 17, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29157881/deformation-of-avian-middle-ear-structures-under-static-pressure-loads-and-potential-regulation-mechanisms
#13
Raf Claes, Pieter G G Muyshondt, Joris J J Dirckx, Peter Aerts
Static pressure changes can alter the configuration and mechanical behavior of the chain of ossicles, which may affect the acoustic transfer function. In mammals, the Eustachian tube plays an important role in restoring ambient middle ear pressure, hence restoring the acoustic transfer function and excluding barotrauma of the middle and inner ear. Ambient pressure fluctuations can be potentially extreme in birds and due to the simple structure of the avian middle ear (one ossicle, one muscle), regulation of the middle ear pressure via reflexive opening of the pharyngotympanic tube appears all the more important...
November 7, 2017: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/29157518/mechanical-circulatory-support-for-high-risk-pulmonary-embolism
#14
REVIEW
Mahir Elder, Nimrod Blank, Adi Shemesh, Mohit Pahuja, Amir Kaki, Tamam Mohamad, Theodore Schreiber, Jay Giri
Temporary mechanical circulatory support (MCS) devices have a role in treating high-risk patients with pulmonary embolism with cardiogenic shock. Mechanical circulatory device selection should be made based on center experience and device-specific features. All current devices are effective in decreasing right arterial pressure and providing circulatory support of 4 to 5 L/min. The pulmonary artery pulsatility index may prove to be an unreliable method to assess right ventricular function. Careful clinical evaluation on an individual patient basis should determine the need for MCS...
January 2018: Interventional cardiology clinics
https://www.readbyqxmd.com/read/29157250/ozone-exposure-is-associated-with-acute-changes-in-inflammation-fibrinolysis-and-endothelial-cell-function-in-coronary-artery-disease-patients
#15
Jaime E Mirowsky, Martha Sue Carraway, Radhika Dhingra, Haiyan Tong, Lucas Neas, David Diaz-Sanchez, Wayne Cascio, Martin Case, James Crooks, Elizabeth R Hauser, Z Elaine Dowdy, William E Kraus, Robert B Devlin
BACKGROUND: Air pollution is a major risk factor for cardiovascular disease, of which ozone is a major contributor. Several studies have found associations between ozone and cardiovascular morbidity, but the results have been inconclusive. We investigated associations between ozone and changes across biological pathways associated with cardiovascular disease. METHODS: Using a panel study design, 13 participants with coronary artery disease were assessed for markers of systemic inflammation, heart rate variability and repolarization, lipids, blood pressure, and endothelial function...
November 21, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29156004/obesity-modulates-the-association-between-systolic-blood-pressure-and-albuminuria
#16
James Fotheringham, Bisher Kawar, William McKane, Timothy Ellam
Background: Obesity is associated with albuminuria and incident kidney disease. Increased vulnerability of the glomerular microcirculation to elevated systemic blood pressure is postulated to contribute to adverse effects of obesity on the kidney. We therefore hypothesized that obesity would modulate the association between systolic blood pressure (sBP) and albuminuria. Methods: The relationship between obesity and albuminuria [fractional albumin excretion (FE alb ) or albumin:creatinine ratio (ACR)] was modelled using linear/logistic regression in the US National Health and Nutrition Examination Survey 1999-2010 cohorts ( N  = 23 710)...
May 30, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29155921/aridification-as-a-driver-of-biodiversity-a-case-study-for-the-cycad-genus-dioon-zamiaceae
#17
José Said Gutiérrez-Ortega, Takashi Yamamoto, Andrew P Vovides, Miguel Angel Pérez-Farrera, José F Martínez, Francisco Molina-Freaner, Yasuyuki Watano, Tadashi Kajita
Background and Aims: Aridification is considered a selective pressure that might have influenced plant diversification. It is suggested that plants adapted to aridity diversified during the Miocene, an epoch of global aridification (≈15 million years ago). However, evidence supporting diversification being a direct response to aridity is scarce, and multidisciplinary evidence, besides just phylogenetic estimations, is necessary to support the idea that aridification has driven diversification...
November 16, 2017: Annals of Botany
https://www.readbyqxmd.com/read/29155883/admixture-mapping-in-the-hispanic-community-health-study-study-of-latinos-reveals-regions-of-genetic-associations-with-blood-pressure-traits
#18
Tamar Sofer, Leslie J Baier, Sharon R Browning, Timothy A Thornton, Gregory A Talavera, Sylvia Wassertheil-Smoller, Martha L Daviglus, Robert Hanson, Sayuko Kobes, Richard S Cooper, Jianwen Cai, Daniel Levy, Alex P Reiner, Nora Franceschini
Admixture mapping can be used to detect genetic association regions in admixed populations, such as Hispanics/Latinos, by estimating associations between local ancestry allele counts and the trait of interest. We performed admixture mapping of the blood pressure traits systolic and diastolic blood pressure (SBP, DBP), mean arterial pressure (MAP), and pulse pressure (PP), in a dataset of 12,116 participants from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Hispanics/Latinos have three predominant ancestral populations (European, African, and Amerindian), for each of which we separately tested local ancestry intervals across the genome...
2017: PloS One
https://www.readbyqxmd.com/read/29155569/redox-behavior-of-a-dinuclear-ruthenium-ii-complex-bearing-an-uncommon-bridging-ligand-insights-from-high-pressure-electrochemistry
#19
Maximilian Dürr, Johannes Klein, Axel Kahnt, Sabine Becker, Ralph Puchta, Biprajit Sarkar, Ivana Ivanović-Burmazović
A dinuclear ruthenium complex bridged by 2,3,5,6-pyrazinetetracarboxylic acid (μ-LH2(2-)) was synthesized and characterized by X-ray crystallography, cyclic voltammetry under ambient and elevated pressures, electron paramagnetic resonance (EPR) and UV/vis-NIR (NIR = near-infrared) spectroelectrochemistry, pulse radiolysis, and computational methods. We probed for the first time in the field of mixed-valency the use of high-pressure electrochemical methods. The investigations were directed toward the influence of the protonation state of the bridging ligand on the electronic communication between the ruthenium ions, since such behavior is interesting in terms of modulating redox chemistry by pH...
November 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29155412/tunable-nanostructured-columnar-growth-of-sno2-for-efficient-detection-of-co-gas
#20
Avneet Singh, Anjali Sharma, Monika Tomar, Vinay Gupta
Present work is focused on the growth and modification of the columnar nanostructures of SnO2 using Glancing Angle Deposition (GLAD) assisted rf sputtering technique for low temperature detection of carbon monoxide (CO) gas. GLAD angle and deposition pressure have been optimized to tailor the grow of columnar nanostructures of SnO2, which exhibited enhanced gas sensing response of 1.49×102 towards 500 ppm of CO gas at a comparatively lower operating temperature of 110°C. The enhanced sensing response at low operating temperature is related to the growth of nanoporous columnar structures of SnO2 thin film under GLAD configuration which results in an enhanced interaction of target CO gas molecules with the large surface area of sensing SnO2 thin film...
November 20, 2017: Nanotechnology
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