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https://www.readbyqxmd.com/read/28428481/serum-tartrate-resistant-acid-phosphatase-5b-levels-are-associated-with-the-severity-and-extent-of-coronary-atherosclerosis-in-patients-with-coronary-artery-disease
#1
Taichirou Morisawa, Akihiro Nakagomi, Keiichi Kohashi, Yoshiki Kusama, Wataru Shimizu
AIMS: Tartrate-resistant acid phosphatase (TRACP)-5b and osteoprotegerin (OPG) are specific and sensitive markers of bone resorption in patients with rheumatoid arthritis (RA) and chronic kidney disease (CKD). The TRACP-5b level is associated with the severity of RA and CKD, while the OPG level is associated with the severity of coronary atherosclerosis and calcification, and can predict a poor outcome in patients with coronary artery disease (CAD). However, the impact of TRACP-5b on coronary atherosclerosis in CAD patients remains unclear...
April 19, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28375096/evaluation-on-curative-effect-and-safety-of-interventional-treatment-for-patients-with-acute-myocardial-infarction
#2
Yinchuan Zhu, Jianmin Tang, Feifei Pei
To evaluate the effectiveness and recent safety of emergency and selective percutaneous coronary intervention (PCI) in elderly patients (>80 years old) with acute myocardial infarction (AMI). 120 elderly patients with coronary heart disease (CHD) were divided into AMI group (with 55 cases) and non-myocardial infarction group (control group with 65 cases). Among the AMI group, there were 18 cases underwent emergency PCI within 12 hours after the onset, (AMI emergency PCI group), the rest 37 cases were AMI selective PCI group...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28349060/serum-cytokine-profile-in-relation-to-the-severity-of-coronary-artery-disease
#3
Xiaoyan Min, Miao Lu, Su Tu, Xiangming Wang, Chuanwei Zhou, Sen Wang, Sisi Pang, Jin Qian, Yiyue Ge, Yan Guo, Di Xu, Kejiang Cao
Objectives. To investigate the potential association of a set of serum cytokines with the severity of coronary artery disease (CAD). Methods. A total of 201 patients who underwent coronary angiography for chest discomfort were enrolled. The concentrations of serum IFN-γ, TNF-α, IL-2, IL-4, IL-6, IL-10, IL-9, and IL-17 were determined by xMAP multiplex technology. The CAD severity was assessed by Gensini score (GS). Results. The serum levels of TNF-α, IL-6, IL-9, IL-10, and IL-17 were significantly higher in high GS group (GS ≥ 38...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28336922/novel-and-traditional-lipid-related-biomarkers-and-their-combinations-in-predicting-coronary-severity
#4
Sha Li, Yuan-Lin Guo, Xi Zhao, Yan Zhang, Cheng-Gang Zhu, Na-Qiong Wu, Rui-Xia Xu, Ping Qing, Ying Gao, Xiao-Lin Li, Jing Sun, Geng Liu, Qian Dong, Jian-Jun Li
We investigated simultaneously traditional and novel lipid indices, alone or in combination, in predicting coronary severity assessed by Gensini score (GS) in 1605 non-lipid-lowering-drug-treated patients undergoing coronary angiography. Firstly, levels of triglycerides (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), non high density lipoprotein cholesterol (non-HDL-C), apolipoprotein (apo) B, lipoprotein (a) [Lp(a)], proprotein convertase subtilisin/kexin type 9 (PCSK9), apoC3, small dense LDL (sdLDL) and large HDL were increased, while HDL-C and apoA1 levels were decreased as GS status (all p for trend <0...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28321241/free-triiodothyronine-in-relation-to-coronary-severity-at-different-ages-gensini-score-assessment-in-4206-euthyroid-patients
#5
Bing-Yang Zhou, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Ying Gao, Ping Qing, Xiao-Lin Li, Yao Wang, Geng Liu, Qian Dong, Jian-Jun Li
OBJECTIVE: To study whether free triiodothyronine (FT3) within normal range has effects on the presence and severity of coronary artery disease (CAD) in different gender and age groups. METHODS: A total of 4206 euthyroid patients were consecutively enrolled and divided into CAD group (n = 3306) and non-CAD group (n = 900). All patients underwent coronary angiography (CAG). Gensini score (GS) was used to determine the severity of coronary artery stenosis. Severe CAD was defined as GS > 32 and mild CAD was defined as GS ≤ 32...
December 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28321018/coronary-artery-disease-in-premenopausal-and-postmenopausal-women
#6
Lu Yihua, Jiang Yun, Zhao Dongshen
The purpose was to determine the differences between premenopausal and postmenopausal coronary artery disease (CAD) risk factors, clinical manifestation, cardiovascular features, rates of recurrence, and influencing factors.Premenopausal (n = 57) and postmenopausal (n = 178) CAD women hospitalized during the same period were enrolled. All patients were followed-up, and the combined recurrence of major adverse cardiovascular events was recorded as the clinical outcome. Differences were compared between the 2 groups...
March 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28315571/the-relationship-of-micronucleus-frequency-and-nuclear-division-index-with-coronary-artery-disease-syntax-and-gensini-scores
#7
Emrah İpek, Emrah Ermiş, Handan Uysal, Halit Kızılet, Selami Demirelli, Erkan Yıldırım, Sedat Ünver, Bircan Demir, Nergiz Kızılet
OBJECTIVE: We aimed to evaluate the relationship of micronucleus (MN) frequency and nuclear division index (NDI) with SYNTAX and Gensini scores and thrombolysis in myocardial infarction (TIMI) frame counts of coronary arteries in patients undergoing coronary angiography. METHODS: In a single-center prospective observational study, a total of 63 individuals, 48 consecutive patients with coronary artery disease (CAD) and 15 healthy people were included. Before coronary angiography (exposure to X-ray), blood samples were collected for lymphocyte cultures, MN and NDI measurements...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28303849/effect-of-metabolic-syndrome-score-metabolic-syndrome-and-its-individual-components-on-the-prevalence-and-severity-of-angiographic-coronary-artery-disease
#8
Ming-Hui Gui, Yan Ling, Lin Liu, Jing-Jing Jiang, Xiao-Ying Li, Xin Gao
BACKGROUND: The clinical significance of metabolic syndrome (MS) score, MS, and its individual components with respect to risk prediction of coronary artery disease (CAD) remains unclear. The objective of this study was to investigate whether and to what extent MS score, MS, and its individual components were related to the risk of CAD. METHODS: Among 1191 participants who underwent coronary angiography for the confirmation of suspected myocardial ischemia, 858 were included in this study according to the inclusion criteria from September 2010 to June 2013...
March 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28292380/correlation-of-c-reactive-protein-and-cardiac-enzymes-with-angiographic-severity-of-coronary-artery-disease-in-pakistani-patients-with-acute-coronary-syndrome
#9
Ayesha Saleem, Azmat Ali
OBJECTIVE: To determine the correlation of C-reactive protein (CRP) levels with the severity of coronary stenosis on angiography and the association of cardiac enzymes with the degree of stenosis in acute coronary syndrome (ACS) patients. Secondly, to compare association of angiographic severity of vascular stenosis with CRP in patients with ST segment elevation myocardial infarction (STEMI) and non-STEMI / Unstable angina (UA). STUDY DESIGN: Prospective, descriptive study...
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28290907/-combination-of-visual-and-metabolic-markers-in-assessment-of-probability-of-presence-and-severity-of-atherosclerosis-of-coronary-arteries
#10
V A Metelskaya, N E Gavrilova, N G Gumanova, O A Litinskaya, E B Yarovaya, S A Boytsov
AIM: to assess possibilities of the use of biochemical markers combined with data of methods of imaging of arterial atherosclerotic lesions for evaluation of risk of presence and severity of coronary atherosclerosis. MATERIALS AND METHODS: We enrolled into this study patients (n=205, 136 men, 69 women, age 33-85 years, 94% on statin therapy) who underwent coronary angiography and carotid artery ultrasound dopplerography. Examination included determination of parameters of lipid profile and carbohydrate metabolism, markers of inflammation and metabolism of visceral adipose tissue...
July 2016: Kardiologiia
https://www.readbyqxmd.com/read/28283374/outcomes-after-a-left-anterior-descending-artery-endarterectomy-in-advanced-coronary-artery-disease
#11
Charalampos Katselis, George Samanidis, Anastasia Papasotiriou, George Karatasakis, Ioannis Nenekidis, Eftichia Demerouti, Theofani Antoniou, Konstantinos Perreas
BACKGROUND: Coronary endarterectomy albeit infrequently utilized remains a pivotal treatment modality for advanced atherosclerotic heart disease. Benefits of coronary endarterectomy are explored in terms of better mid-term survival, freedom of major adverse cardiac and cerebrovascular events and improved left ventricular ejection fraction. METHODS: 50 patients with coronary artery disease including extensive diffuse LAD disease underwent a left anterior descending artery endarterectomy with coronary by-pass grafting and left internal mammary artery as conduit between 2006 and 2014...
February 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28262908/relationship-between-myocardial-performance-index-and-severity-of-coronary-artery-disease-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome
#12
Okay Abaci, Cuneyt Kocas, Veysel Oktay, Sukru Arslan, Yusuf Turkmen, Cem Bostan, Ugur Coskun, Ahmet Yildiz, Murat Ersanli
OBJECTIVES: We aimed to investigate the relationship between myocardial performance index (MPI) and severity of coronary artery disease, as assessed by the Gensini score (GS), in patients with non-ST-segment elevation myocardial infarction (NSTEMI). METHODS: Ninety patients with an initial diagnosis of NSTEMI were enrolled in our study. They were divided into tertiles according to the GS: low GS < 19; mid GS > 19 and ≤ 96; and high GS > 96. RESULTS: The low-, mid- and high-GS groups included 24, 38 and 28 patients, respectively...
January 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28249620/high-levels-of-serum-%C3%AE-2-microglobulin-predict-severity-of-coronary-artery-disease
#13
Ling You, Ruiqin Xie, Haijuan Hu, Guoqiang Gu, Hongmei Zheng, Jidong Zhang, Xiaohong Yang, Ximiao He, Wei Cui
BACKGROUND: The identification of new risk factors for coronary artery disease (CAD) is increasingly sought in an effort to tackle this threatening disease. β2-microglobulin (B2M) is reported to associate with peripheral arterial disease and adverse cardiovascular outcomes. However, the association between B2M and cardiovascular disease remains under-researched. This study evaluated the effects of B2M on CAD without renal dysfunction. METHODS: One thousand seven hundred sixty-two subjects (403 non-CAD subjects and 1,359 CAD subjects) were investigated...
March 1, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28242046/association-between-peripheral-blood-cells-mitochondrial-dna-content-and-severity-of-coronary-heart-disease
#14
Li-Peng Liu, Kang Cheng, Ming-An Ning, Hong-Hong Li, Hai-Chang Wang, Fei Li, Shu-Ying Chen, Fa-Lin Qu, Wen-Yi Guo
BACKGROUND AND AIMS: Leukocyte mitochondrial DNA (mtDNA) content reflects the oxidant-induced cell damage, which has been observed in a wide range of cardiovascular diseases. However, whether it correlates with coronary heart disease (CHD), which closely relates to oxidative stress, has never been elucidated before. The aim of this study was to explore association between mtDNA content and the presence and severity of CHD. METHODS: The study population consisted of 400 individuals (290 with CHD and 110 controls)...
February 20, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28241795/impact-of-multi-vessel-therapy-to-the-risk-of-periprocedural-myocardial-injury-after-elective-coronary-intervention-exploratory-study
#15
Zhang-Wei Chen, Hong-Bo Yang, Ying-Hua Chen, Jian-Ying Ma, Ju-Ying Qian, Jun-Bo Ge
BACKGROUNDS: Periprocedural myocardial injury (PMI) after elective percutaneous coronary intervention (PCI) significantly influences the prognosis of coronary artery disease (CAD). However, it was unclear whether the occurrence of PMI was associated with a series of controllable factors, such as PCI strategy or severity of CAD. METHODS: A total of 544 consecutive stable CAD patients underwent elective PCI were enrolled. The main outcome is PMI, defined as troponin T after PCI was at least one value above the 99th percentile upper reference limit...
February 27, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28239809/association-between-the-plasma-levels-of-ima-and-coronary-atherosclerotic-plaque-burden-and-ischemic-burden-in-early-phase-of-non-st-segment-elevation-acute-coronary-syndromes
#16
T Turan, A R Akyüz, S Sahin, S Kul, A S Yilmaz, F Kara, S O Mentese, A Ç Aykan, S Demir, S Celik, S C Karahan
OBJECTIVE: Ischemia-modified albumin (IMA), a novel biochemical marker, is known to reflect ischemia in early phases of acute coronary syndrome (ACS). In the present study, we evaluated the role of IMA on the prediction of coronary atherosclerotic plaque burden and ischemic burden in patients with non-ST-segment-elevation acute coronary syndromes (NSTEACS). PATIENTS AND METHODS: Ninety-six consecutive NSTEACS patients presented within the first three hours of symptom onset were prospectively enrolled in this study...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28238617/interaction-between-vitamin-d-and-lipoprotein-a-on-the-presence-and-extent-of-coronary-heart-disease
#17
Kuibao Li, Xiyan Yang, Lefeng Wang, Mulei Chen, Li Xu, Xinchun Yang
BACKGROUND: Given both lipoprotein (Lp)(a) and vitamin D have been found to be associated with coronary heart disease (CHD) risk and a biochemical link between vitamin D and cholesterol on atherosclerosis has been proposed, we hypothesised there could exist an interaction between Lp(a) and vitamin D on the severity of CHD. METHODS: Lp(a) and 25-OH vitamin D were measured in the plasma of 348 consecutive patients (mean age 62.4±10.5 years; 56.3% male) undergoing coronary angiography at our Heart Center...
February 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28210011/relationship-of-plasma-adiponectin-and-waist-hip-ratio-with-coronary-artery-disease
#18
Premtim Rashiti, Shpend Elezi, Ibrahim Behluli, Sefedin Mucaj
BACKGROUND: This study aimed to investigate correlation between adiponectin and waist-hip-ratio with severity of coronary artery disease (CAD). There is uncertainty about the association between circulating concentrations of adiponectin and CAD. METHODS: We enrolled eighty-two consecutive patients undergoing non-urgent coronary angiography for CAD survey. According to the angiography results, the patients were divided into two groups in 1:1 ratio patients admitted with a diagnosis of CAD and non-CAD...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28167479/evaluation-on-curative-effect-and-safety-of-interventional-treatment-for-patients-with-acute-myocardial-infarction
#19
Yinchuan Zhu, Jianmin Tang, Feifei Pei
To evaluate the effectiveness and recent safety of emergency and selective percutaneous coronary intervention (PCI) in elderly patients (>80 years old) with acute myocardial infarction (AMI). 120 elderly patients with coronary heart disease (CHD) were divided into AMI group (with 55 cases) and non-myocardial infarction group (control group with 65 cases). Among the AMI group, there were 18 cases underwent emergency PCI within 12 hours after the onset, (AMI emergency PCI group), the rest 37 cases were AMI selective PCI group...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28143410/correlations-of-serum-cystatin-c-and-glomerular-filtration-rate-with-vascular-lesions-and-severity-in-acute-coronary-syndrome
#20
Jinjin Zhang, Xianhao Wu, Peizhen Gao, Pingping Yan
BACKGROUND: The aim of this study was to evaluate the predictive value of cystatin C (CysC) and estimated glomerular filtration rate (eGFR) regarding vascular lesions and their severity in patients with acute coronary syndrome (ACS). METHODS: According to the results of coronary angiography, 195 ACS patients were divided into a single-vascular-lesion group (91 cases), a dual-vascular-lesion group (67 cases), and a multiple-vascular-lesion group (37 cases) to assess the severity of coronary artery disease according to Gensini scores and to analyze the correlations of CysC and eGFR level with vascular lesions and severity in ACS patients...
January 31, 2017: BMC Cardiovascular Disorders
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