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https://www.readbyqxmd.com/read/27899855/evaluation-of-echocardiographic-epicardial-fat-thickness-as-a-sign-of-cardiovascular-risk-in-positive-exercise-test-patients
#1
Hüseyin Katlandur, Şeref Ulucan, Hüseyin Özdil, Ahmet Keser, Zeynettin Kaya, Kerem Özbek, M Sıddık Ülgen
BACKGROUND: The association between epicardial fat thickness (EFT) and positive exercise test results for the diagnosis of coronary artery diseases (CAD) has yet to be evaluated. This study assessed the predictive value of EFT for CAD on the angiographs of patients with positive exercise tests. METHODS: A total of 91 subjects were chosen consecutively from stable angina pectoris patients who were referred for coronary angiography due to a positive exercise test result...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27882261/prevalence-of-hepatitis-c-virus-seropositivity-and-its-impact-on-coronary-artery-disease-among-egyptian-patients-referred-for-coronary-angiography
#2
Ragab Abd El Salam, Baher Nabil, Marawan Saber, Hany A AbdelWahab, Tamer Saber
Background. We tested the prevalence and impact of HCV seropositivity among Egyptian patients referred for coronary angiography. Subjects and Methods. This cross-sectional study was conducted in Zagazig University hospitals including 509 patients scheduled for elective coronary angiography between June 2013 and June 2014. By taking full history on admission, laboratory workup including HCV Ab, echocardiography study, and coronary angiography, we calculated the mean number of coronary artery lesions and the mean number of affected coronary artery vessels for all patients...
2016: Cardiology Research and Practice
https://www.readbyqxmd.com/read/27835972/the-association-of-functional-polymorphisms-in-genes-encoding-growth-factors-for-endothelial-cells-and-smooth-muscle-cells-with-the-severity-of-coronary-artery-disease
#3
Tadeusz Osadnik, Joanna Katarzyna Strzelczyk, Andrzej Lekston, Rafał Reguła, Kamil Bujak, Martyna Fronczek, Marcin Gawlita, Małgorzata Gonera, Jarosław Wasilewski, Bożena Szyguła-Jurkiewicz, Marek Gierlotka, Mariusz Gąsior
BACKGROUND: Despite the important roles of vascular smooth muscle cells and endothelial cells in atherosclerotic lesion formation, data regarding the associations of functional polymorphisms in the genes encoding growth factors with the severity of coronary artery disease (CAD) are lacking. The aim of the present study is to analyze the relationships between functional polymorphisms in genes encoding basic fibroblast growth factor (bFGF, FGF2), epidermal growth factor (EGF), insulin-like growth factor-1 (IGF-1), platelet derived growth factor-B (PDGFB), transforming growth factor-β1 (TGF-β1) and vascular endothelial growth factor A (VEGF-A) and the severity of coronary atherosclerosis in patients with stable CAD undergoing their first coronary angiography...
November 11, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27831644/study-on-the-levels-of-uric-acid-and-high-sensitivity-c-reactive-protein-in-acs-patients-and-their-relationships-with-the-extent-of-the-coronary-artery-lesion
#4
Q-Q Ma, X-J Yang, N-Q Yang, L Liu, X-D Li, K Zhu, Q Fu, P Wei
OBJECTIVE: We evaluated uric acid (UA) and high-sensitivity C-reactive protein (hs-CRP) levels in different clinical types of acute coronary syndromes (ACS) and in relationship with the severity of coronary artery lesions. Furthermore, we explored its clinical significance. PATIENTS AND METHODS: From June 2013 to January 2015, we studied patients in their first onset of symptoms and hospitalization for coronary angiography. According to coronary angiography results, we divided patients into two groups: 93 patients with ACS and 30 patients with normal coronary arteries as the control group...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27826341/the-association-between-platelet-lymphocyte-ratio-and-coronary-artery-disease-severity-in-asymptomatic-low-ejection-fraction-patients
#5
Fatih Mehmet Uçar, Burak Açar, Murat Gul, Özcan Özeke, Sinan Aydogdu
BACKGROUND AND OBJECTIVES: Coronary angiography (CAG) is generally needed in the setting of systolic heart failure (HF) with an unidentified etiology as a part of diagnostic strategy. On the other hand, the clinical value of this invasive strategy is largely unknown. Platelet-lymphocyte ratio (PLR) has recently emerged as a novel inflammatory index that may serve as an important predictor of inflammatory state and overall mortality. The present study aimed to search the predictive value of PLR in determining the extent of coronary atherosclerosis in asymptomatic low ejection fraction (EF) patients...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27825299/lipoprotein-a-and-lipid-profiles-of-patients-awaiting-coronary-artery-bypass-graft-a-cross-sectional-study
#6
E M S Bandara, S Ekanayake, C A Wanigatunge, A Kapuruge
BACKGROUND: Lipoprotein(a) (Lp(a)) excess is an independent risk factor of coronary artery disease (CAD) and have shown wide ethnic variations. Further, lipid parameters used in the assessment and management of risk factors for CAD may not reflect accurately the disease or severity if the patients are on pharmacological interventions when compared to Lp(a). Lp(a) levels of Sri Lankan CAD patients awaiting coronary artery bypass graft are not documented. METHODS: A cross sectional study was carried out with patients (n = 102) awaiting coronary artery bypass graft at a tertiary healthcare institution in Sri Lanka...
November 8, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27815939/endothelial-lipase-plasma-levels-are-increased-in-both-sexes-in-stable-coronary-artery-disease-and-only-in-women-with-acute-coronary-syndrome-but-not-associated-with-the-severity-of-coronary-artery-disease
#7
Matias Trbušić, Ines Potočnjak, Beate Tiran, Tomislava Bodrožić-Džakić, Milan Milošević, Vesna Degoricija, Saša Frank
AIM: To investigate whether endothelial lipase (EL) plasma levels are increased in stable coronary artery disease (sCAD) and acute coronary syndrome (ACS) patients, as well as to test the association of EL plasma levels and the severity of CAD and sex. METHODS: The study was performed as a single-center, cross-sectional, observational research on 72 sCAD and 187 ACS patients in the Sisters of Charity University Hospital Centre, Zagreb, Croatia, between December 1, 2011 and December 1, 2012...
October 31, 2016: Croatian Medical Journal
https://www.readbyqxmd.com/read/27790354/assosiation-of-epicardial-and-pericardial-fat-thickness-with-coronary-artery-disease
#8
Fereshteh Ghaderi, Ali Eshraghi, Alireza Sepehri Shamloo, Sareh Mousavi
INTRODUCTION: Visceral adipose tissue is a known important risk factor for coronary artery disease (CAD). While some studies have suggested relationship between epicardial fat thickness (EFT) and CAD, there are no adequate studies for pericardial fat thickness (PFT). The aim of this study was to determine the association of EFT and PFT with CAD. METHODS: This cross-sectional study was conducted on patients who were candidates for elective coronary artery angiography, referred to Emam Reza Hospital, Mashhad, Iran during Jan 2014-2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27781059/relationship-of-lipid-and-lipoprotein-ratios-with-coronary-severity-in-patients-with-new-on-set-coronary-artery-disease-complicated-with-type-2-diabetics
#9
Ying Du, Juan Chen, Man-Hua Chen, Sheng-Hua Yang, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Rui-Xia Xu, Qian Dong, Jian-Jun Li
BACKGROUND: Diabetes mellitus (DM) is associated with coronary artery disease (CAD) progression. Although previous studies have demonstrated the association of lipid and lipoprotein ratios with CAD, no data are currently available concerning the relationship between lipid and lipoprotein ratios and the severity of new on-set CAD in diabetics. Therefore, the aim of the present study was to investigate the usefulness of lipid and lipoprotein ratios in predicting the severity of CAD in patients with type 2 DM (T2DM)...
August 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27721854/association-between-the-gensini-score-and-carotid-artery-stenosis
#10
Anil Avci, Serdar Fidan, Mehmet Mustafa Tabakçı, Cuneyt Toprak, Elnur Alizade, Emrah Acar, Emrah Bayam, Muhammet Tellice, Abdurrahman Naser, Ramazan Kargın
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the association between the extent of coronary artery disease assessed by the Gensini score and/or the SYNTAX score and the significant carotid stenosis in patients undergoing coronary artery bypass grafting (CABG). SUBJECTS AND METHODS: A total of 225 patients who had carotid doppler ultrasonography prior to CABG were included retrospectively. Significant coronary artery disease was assumed as a lumen diameter stenosis of ≥50% in any of the major epicardial coronary arteries...
September 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27721851/association-of-rs10757274-and-rs2383206-polymorphisms-on-9p21-locus-with-coronary-artery-disease-in-turkish-population
#11
Çağrı Yayla, Kaan Okyay, Akın Yılmaz, Asife Şahinarslan, Atiye Seda Yar Sağlam, Azmi Eyiol, Hasan Ata Bolayır, Burak Sezenöz, Sevda Menevşe, Atiye Çengel
BACKGROUND AND OBJECTIVES: Genetic predisposition is an important risk factor for coronary artery disease (CAD). In this study, we aimed to evaluate the impact of rs10757274 and rs2383206 polymorphisms in chromosome 9p21 on presence and severity of CAD in a Turkish population. SUBJECTS AND METHODS: A total of 646 patients who underwent coronary angiography were included in this study. Coronary vessel score and Gensini score were calculated to assess the angiographic severity of CAD...
September 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27716220/the-apoa5-rs662799-polymorphism-is-associated-with-dyslipidemia-and-the-severity-of-coronary-heart-disease-in-chinese-women
#12
Yanmei Wang, Zhan Lu, Jingxiao Zhang, Yang Yang, Jing Shen, Xiaoming Zhang, Yongyan Song
BACKGROUND: The APOA5 rs662799 polymorphism has been widely reported regarding its associations with the plasma lipid levels and the occurrence of coronary heart disease (CHD), whereas its relationship with the severity of CHD has not yet been explored. METHODS: Four hundred and seventy-eight angiografically defined subjects (325 CHD patients and 153 CHD-free controls) were enrolled in this study. The rs662799 polymorphism was genotyped, and the fasting lipid data were collected for all participants...
September 30, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27714720/effect-of-epicardial-adipose-tissue-thickness-on-left-ventricular-diastolic-functions-in-patients-with-normal-coronary-arteries
#13
Mustafa Topuz, Ali Dogan
BACKGROUND: The aim of this study is to evaluate the effect of epicardial adipose tissue (EAT) thickness on left ventricular diastolic functions in patients with normal coronary arteries (NCA) proven by angiography. METHODS: We selected study patients who were referred to coronary angiography due to typical chest pain or atypical chest pain with a positive pre-test result for coronary artery disease. After coronary angiography, 85 patients had significant coronary lesion (≥50% stenosis) served as coronary artery disease (CAD) group, 82 patients had non-significant coronary lesion (<50% stenosis) and/or a coronary plaque served as non-significant CAD group and 83 patients had normal coronary arteries served as normal coronary artery (NCA) group...
October 7, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27698725/assessment-of-myocardial-viability-with-delayed-enhancement-mri-in-coronary-artery-disease-a-correlative-study-with-coronary-artery-stenosis-using-digital-subtraction-angiography
#14
Xinxiang Zhao, Yanglin Zhang, Yong Sun, Lin Sun, Renhui Cai
The aim of the present study was to investigate the correlation between the degree of coronary artery stenosis determined by digital subtraction angiography (DSA) and infarcted segments detected by delayed enhancement magnetic resonance imaging (DE-MRI). DE-MRI and DSA were performed in 40 patients with coronary artery disease. The number of myocardial segments with infarction, the transmural extent of myocardial infarction, score of myocardial infarction by MRI, degree of coronary artery stenosis and Gensini score of the coronary artery were assessed...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27676253/residual-thrombin-potential-predicts-cardiovascular-death-in-acute-coronary-syndrome-patients-undergoing-percutaneous-coronary-intervention
#15
Monica Attanasio, Rossella Marcucci, Anna Maria Gori, Rita Paniccia, Serafina Valente, Daniela Balzi, Alessandro Barchielli, Nazario Carrabba, Renato Valenti, David Antoniucci, Rosanna Abbate, Gian Franco Gensini
INTRODUCTION: Thrombin generation (TG) is a central step of the coagulation system involved in hemostatic and thrombotic roles. Scarce data evaluating in the acute phase the association between TG and the risk of cardiovascular death of acute coronary syndrome (ACS) patients are available, in the era of percutaneous coronary intervention (PCI) and stenting with the use of dual antiplatelet treatment. MATERIALS AND METHODS: We investigated TG in 292 ACS patients undergoing PCI with stent implantation on dual antiplatelet treatment...
November 2016: Thrombosis Research
https://www.readbyqxmd.com/read/27641081/the-prediction-roles-of-asymmetric-dimethyl-arginine-adiponectin-and-apelin-for-macroangiopathy-in-patients-with-impaired-glucose-regulation
#16
Shan Huang, Dajin Zou, Wenfang Peng, Xiaohong Jiang, Kan Shao, Lili Xia, Yubin Tang
PURPOSE: To investigate the effects of asymmetric dimethyl-arginine (ADMA), adiponectin (APN) and apelin in predicting macroangiopathy in impaired glucose regulation (IGR) patients. METHODS: A total of 210 patients undergoing oral glucose tolerance test were included in this study. They were classified to normal glucose tolerance (NGT, n=42), impaired fasting glucose (IFG, n=36), impaired glucose tolerance (IGT, n=92, including 44 IGT1 and 48 IGT2 patients) and IFG+IGT (n=40) groups...
December 2016: Annales D'endocrinologie
https://www.readbyqxmd.com/read/27634241/non-hdl-c-is-a-better-predictor-for-the-severity-of-coronary-atherosclerosis-compared-with-ldl-c
#17
Yan Zhang, Na-Qiong Wu, Sha Li, Cheng-Gang Zhu, Yuan-Lin Guo, Ping Qing, Ying Gao, Xiao-Lin Li, Geng Liu, Qian Dong, Jian-Jun Li
BACKGROUND: Recent guidelines recommended both low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) are the primary target of lipid modulating therapy. However, which lipid measure is most closely related to the severity of coronary atherosclerosis has not yet been assessed. METHODS: We studied 1757 consecutive subjects undergoing coronary angiography who were not receiving any lipid-lowering therapy. Low-density lipoprotein cholesterol was measured directly, and non-HDL-C was calculated...
October 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27631216/association-of-decreased-serum-strem-1-level-with-the-severity-of-coronary-artery-disease-inhibitory-effect-of-strem-1-on-tnf-%C3%AE-and-oxldl-induced-inflammatory-reactions-in-endothelial-cells
#18
Daopeng Dai, Weixin Xiong, Qin Fan, Haibo Wang, Qiujing Chen, Weifeng Shen, Ruiyan Zhang, Fenghua Ding, Lin Lu, Rong Tao
Soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) is closely involved in autoimmune diseases and inflammatory reactions. We aimed to investigate whether serum sTREM-1 is related to coronary artery disease (CAD) and to evaluate the biological effects of sTREM-1 in cell experiments.This cross-sectional study included 263 consecutive patients with angiographically documented CAD, who were admitted for diagnosis and interventional treatment of CAD (CAD group), with 162 participants without CAD serving as controls (control group)...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27621866/chronic-kidney-disease-and-the-severity-of-coronary-artery-disease-and-retinal-microvasculature-changes-a-cross-sectional-study
#19
Kevin Phan, Cheryl Au, Paul Mitchell, Gerald Liew, Adam J H Plant, Sarah B Wang, Joseph Chiha, Aravinda Thiagalingam, George Burlutsky, Bamini Gopinath
BACKGROUND: Prior studies have suggested the association between incidence of coronary artery disease (CAD) with chronic kidney disease (CKD) and poor glomerular filtration function. However to the best of our knowledge, few studies have specifically assessed this relationship based on the severity of CAD as quantified using Extent and Gensini scores. METHODS: Between June 2009 and January 2012, data were collected from 1,680 participants as part of the Australian Heart Eye Study (AHES) cohort...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27608903/the-impact-of-the-extent-and-severity-of-coronary-artery-disease-on-fractional-flow-reserve-measurements
#20
E Şahan, S Şahan, M Karamanlıoğlu, M Gül, S Kalaycı, A Boyacı, F Dereağzı
OBJECTIVE: Coronary angiography has a limitation to determine the severity of intermediate stenosis (30-70%)1,2. Fractional flow reserve (FFR) is a method for the assessment of the intermediate stenosis severity3. The effect of coronary artery disease (CAD) severity on the FFR results is not clear. In this study, we aimed to expose the effect of CAD severity calculated with Syntax and Gensini scores on FFR results. PATIENTS AND METHODS: We scanned patients data (n=378) who had undergone fractional flow reserve measurements in our center...
August 2016: European Review for Medical and Pharmacological Sciences
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