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https://www.readbyqxmd.com/read/28632180/preview-prevention-of-diabetes-through-lifestyle-intervention-and-population-studies-in-europe-and-around-the-world-design-methods-and-baseline-participant-description-of-an-adult-cohort-enrolled-into-a-three-year-randomised-clinical-trial
#1
Mikael Fogelholm, Thomas Meinert Larsen, Margriet Westerterp-Plantenga, Ian Macdonald, J Alfredo Martinez, Nadka Boyadjieva, Sally Poppitt, Wolfgang Schlicht, Gareth Stratton, Jouko Sundvall, Tony Lam, Elli Jalo, Pia Christensen, Mathijs Drummen, Elizabeth Simpson, Santiago Navas-Carretero, Teodora Handjieva-Darlenska, Roslyn Muirhead, Marta P Silvestre, Daniela Kahlert, Laura Pastor-Sanz, Jennie Brand-Miller, Anne Raben
Type-2 diabetes (T2D) is one of the fastest growing chronic diseases worldwide. The PREVIEW project has been initiated to find the most effective lifestyle (diet and physical activity) for the prevention of T2D, in overweight and obese participants with increased risk for T2D. The study is a three-year multi-centre, 2 × 2 factorial, randomised controlled trial. The impact of a high-protein, low-glycaemic index (GI) vs. moderate protein, moderate-GI diet in combination with moderate or high-intensity physical activity on the incidence of T2D and the related clinical end-points are investigated...
June 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28627186/%C3%A3-ndice-glic%C3%A3-mico-carga-glic%C3%A3-mica-e-insulina-posprandial-a-dos-f%C3%A3-rmulas-isogluc%C3%A3-dicas-con-distintos-edulcorantes-y-fibra-en-adultos-sanos-y-diab%C3%A3-ticos-tipo-2
#2
Lissé Angarita Dávila, José López Miranda, Daniel Aparicio Camargo, Karla Parra Zuleta, Maria Uzcátegui González, Virginia Céspedes Nava, Samuel Durán Agüero, Nadia Reyna Villasmil
Objetivo: el objetivo de este estudio fue comparar el índice glicémico (IG), la carga glicémica (CG) y la insulina posprandial de dos fórmulas isoglucídicas con distintos edulcorantes y fibra en adultos sanos y diabéticos tipo 2 (DM2).Metodología: en este estudio aleatorizado, cruzado y doble ciego, once sujetos sanos y seis diabéticos consumieron dos fórmulas en cuatro ocasiones (Glucerna SR® Laboratorios Abbott C.A [FG] y Enterex Diabetic®, Victus, C.A [FE], edulcoradas con fructosa y sucralosa respectivamente, con distintas fuentes de fibra), además de solución glucosada (SG) en una ocasión...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28627185/adherencia-y-tolerancia-como-claves-en-la-detenci%C3%A3-n-de-la-p%C3%A3-rdida-de-peso-en-pacientes-oncol%C3%A3-gicos-sometidos-a-radioterapia-mediante-una-estrategia-de-suplementaci%C3%A3-n-precoz-con-una-f%C3%A3-rmula-enteral-hipercal%C3%A3-rica-e-hiperproteica-espec%C3%A3-fica
#3
Jose M García Almeida, Yolanda Lupiáñez Pérez, Mercedes Blanco Naveira, Josefina Ruiz Nava, José Antonio Medina, Isabel Cornejo Pareja, Ana Gómez Pérez, María Molina Vega, José A López-Medina, Francisco Tinahones Madueño
Introducción: en pacientes con riesgo nutricional, la Sociedad Europea de Clínica y Metabolismo (ESPEN) y Parenteral recomienda suplementos nutricionales durante el tratamiento oncológico para prevenir la pérdida de peso involuntaria.Objetivos: nuestro objetivo es conocer el cumplimiento, la aceptabilidad y la tolerancia de un suplemento hiperproteico, hipercalórico, rico en omega 3 en pacientes oncológicos.Métodos: estudio unicéntrico, observacional y prospectivo en pacientes oncológicos con un suplemento nutricional hiperproteico, hipercalórico, rico en omega 3 y de bajo volumen...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28624713/aneuploidy-identification-in-pre-b-acute-lymphoblastic-leukemia-patients-at-diagnosis-by-multiplex-ligation-dependent-probe-amplification-mlpa
#4
A Vázquez-Reyes, L Bobadilla-Morales, C Barba-Barba, G Macías-Salcedo, G Serafín-Saucedo, M E Velázquez-Rivera, M C Almodóvar-Cuevas, A Márquez-Mora, H J Pimentel-Gutiérrez, C Ortega-de-la-Torre, R M Cruz-Osorio, S Nava-Gervasio, J Rivera-Vargas, F Sánchez-Zubieta, J R Corona-Rivera, A Corona-Rivera
Three-quarters of the patients with acute lymphoblastic leukemia (ALL), show numerical or structural chromosomal alterations, which are important factors in leukemogenesis. The use of Multiplex Ligation-dependent Probes Amplification (MLPA) has been mainly limited for searching copy number alterations of genes, suggesting that MLPA could detect numerical alterations in cancer. However, the use of MLPA in pediatrics to analyze subtelomeric sequences for aneuploidy detection has not been considered in previous studies...
June 1, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28624683/drought-responsive-micrornas-in-two-barley-cultivars-differing-in-their-level-of-sensitivity-to-drought-stress
#5
Ehsan Mohseni Fard, Behnam Bakhshi, Reza Keshavarznia, Nava Nikpay, Maryam Shahbazi, Ghasem Hosseini Salekdeh
MicroRNAs (miRNAs) are known to be involved in the regulation of gene expression, including that of genes involved in the response to stress. Here, a comparison has been drawn between the miRNA profiles of a drought susceptible, 'Morocco 9-75', and a drought tolerant, 'Yousef', barley cultivars. Leaf water content, shoot dry matter and chlorophyll content decreased in 'Morocco 9-75' more considerably compared with 'Yousef' under drought stress. Furthermore, lower stomatal conductance and higher leaf temperature were observed in 'Morocco 9-75' compared with 'Yousef'...
June 7, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28618336/left-ventricle-hermite-based-segmentation
#6
Jimena Olveres, Rodrigo Nava, Boris Escalante-Ramírez, Enrique Vallejo, Jan Kybic
In recent years, computed tomography (CT) has become a standard technique in cardiac imaging because it provides detailed information that may facilitate the diagnosis of the conditions that interfere with correct heart function. However, CT-based cardiac diagnosis requires manual segmentation of heart cavities, which is a difficult and time-consuming task. Thus, in this paper, we propose a novel technique to segment endocardium and epicardium boundaries based on a 2D approach. The proposal computes relevant information of the left ventricle and its adjacent structures using the Hermite transform...
May 31, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28613151/stylet-penetration-activities-of-the-whitefly-bemisia-tabaci-associated-with-inoculation-of-the-crinivirus-tomato-chlorosis-virus
#7
Nathalie Kristine Prado Maluta, Elisa Garzo, Aranzazu Moreno, Jesús Navas-Castillo, Elvira Fiallo-Olivé, João Roberto Spotti Lopes, Alberto Fereres
Bemisiatabaci is an important vector of numerous plant viruses, including the emergent semi-persistently transmitted crinivirus Tomato chlorosis virus (ToCV). Its vector feeding behaviour is complex, with important implications for virus transmission, epidemiology and control. Thus, the objective of this study was to investigate the role of the stylet penetration activities of B. tabaci in the inoculation of ToCV in tomatoes by using the electrical penetration graph (EPG) technique. EPG recordings were classified into six categories depending on the waveforms observed...
June 14, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28610638/baderi-an-online-database-to-coordinate-handsearching-activities-of-controlled-clinical-trials-for-their-potential-inclusion-in-systematic-reviews
#8
Hector Pardo-Hernandez, Gerard Urrútia, Leticia A Barajas-Nava, Diana Buitrago-Garcia, Julieth Vanessa Garzón, María José Martínez-Zapata, Xavier Bonfill
BACKGROUND: Systematic reviews provide the best evidence on the effect of health care interventions. They rely on comprehensive access to the available scientific literature. Electronic search strategies alone may not suffice, requiring the implementation of a handsearching approach. We have developed a database to provide an Internet-based platform from which handsearching activities can be coordinated, including a procedure to streamline the submission of these references into CENTRAL, the Cochrane Collaboration Central Register of Controlled Trials...
June 13, 2017: Trials
https://www.readbyqxmd.com/read/28609933/the-genus-i-vieira-i-nav%C3%A3-s-neuroptera-chrysopidae-a-new-species-a-key-to-the-species-and-new-geographic-records
#9
Francisco Sosa, Catherine A Tauber
Vieira Navás is a small genus of Neotropical green lacewings in the tribe Belonopterygini. Here, a fifth species, Vieira flinti sp. nov., is described from Venezuela and Brazil. This species shares significant features with disparate members of the genus; thus the genus as a whole is now known to express a more continuous range of morphological variation than previously recognized. We present a key for identifying Vieira species and new geographic records for previously described species in the genus.
April 26, 2017: Zootaxa
https://www.readbyqxmd.com/read/28609564/ecological-drivers-of-body-size-evolution-and-sexual-size-dimorphism-in-short-horned-grasshoppers-orthoptera-acrididae
#10
Vicente García-Navas, Víctor Noguerales, Pedro J Cordero, Joaquín Ortego
Sexual size dimorphism (SSD) is widespread and variable in nature. Although female-biased SSD predominates among insects, the proximate ecological and evolutionary factors promoting this phenomenon remain largely unstudied. Here, we employ modern phylogenetic comparative methods on 8 subfamilies of Iberian grasshoppers (85 species) to examine the validity of different models of evolution of body size and SSD and explore how they are shaped by a suite of ecological variables (habitat specialization, substrate use, altitude) and/or constrained by different evolutionary pressures (female fecundity, strength of sexual selection, length of the breeding season)...
June 13, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28608574/the-attitude-of-latin-american-immigrants-in-florida-usa-towards-deceased-organ-donation
#11
Antonio Ríos, Ana Isabel López-Navas, José Antonio García, Gregorio Garrido, Marco Antonio Ayala-García, María José Sebastián, Antonio Miguel Hernandez, Pablo Ramírez, Pascual Parrilla
INTRODUCTION: The Latin American (LA) population resident in the USA is a growing subgroup of the population. OBJECTIVE: To find out the structure of attitude towards organ donation in the LA population resident in Florida (USA). METHODS: A sample was taken of LA residents in Florida, randomised and stratified by nationality, age and sex (n=1524). Attitude was assessed using a validated questionnaire (PCID-DTO Rios), that was self-completed anonymously...
June 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28608568/the-macrophage-activation-induced-by-bacillus-thuringiensis-cry1ac-protoxin-involves-erk1-2-and-p38-pathways-and-the-interaction-with-cell-surface-hsp70
#12
Néstor Rubio-Infante, Damaris Ilhuicatzi-Alvarado, Marilu Torres-Martínez, Juan Pablo Reyes-Grajeda, Raúl Nava-Acosta, Edith González-González, Leticia Moreno-Fierros
Here, we aimed to further characterize the mechanisms involved in protoxin (p) Cry1Ac-induced macrophage activation. We demonstrated that pCry1Ac induces MAPK ERK1/2, p38 and JNK phosphorylation in RAW264.7 macrophages. Because MAPK activation is mainly triggered via ligand-receptor interactions, we focused on the identification of potential pCry1Ac-receptor proteins. Flow cytometry and confocal analysis showed specific saturable pCry1Ac-binding to the macrophage surface and evidenced its internalization via the clathrin-pathway...
June 13, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28608135/can-proportional-ventilation-modes-facilitate-exercise-in-critically-ill-patients-a-physiological-cross-over-study-pressure-support-versus-proportional-ventilation-during-lower-limb-exercise-in-ventilated-critically-ill-patients
#13
Evangelia Akoumianaki, Nicolas Dousse, Aissam Lyazidi, Jean-Claude Lefebvre, Severine Graf, Ricardo Luiz Cordioli, Nathalie Rey, Jean-Christophe Marie Richard, Laurent Brochard
BACKGROUND: Early exercise of critically ill patients may have beneficial effects on muscle strength, mass and systemic inflammation. During pressure support ventilation (PSV), a mismatch between demand and assist could increase work of breathing and limit exercise. A better exercise tolerance is possible with a proportional mode of ventilation (Proportional Assist Ventilation, PAV+ and Neurally Adjusted Ventilatory Assist, NAVA). We examined whether, in critically ill patients, PSV and proportional ventilation have different effects on respiratory muscles unloading and work efficiency during exercise...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28606092/hyperlipidemic-microenvironment-conditionates-damage-mechanisms-in-human-chondrocytes-by-oxidative-stress
#14
Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M Reginato, Alberto López-Reyes
BACKGROUND: Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this study was to evaluate the effect of free fatty acids (FFA) in human chondrocytes (HC) expression of proinflammatory factors and reactive oxygen species (ROS). METHODS: HC were exposed to two different concentrations of FFA in order to evaluate the secretion of adipokines through cytokines immunoassays panel, quantify the protein secretion of FFA-treated chondrocytes, and fluorescent cytometry assays were performed to evaluate the reactive oxygen species (ROS) production...
June 12, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28595961/-flexible-bronchoscopy-in-octogenarians
#15
Antonio Noguera-Sánchez, María J Soler-Sempere, Justo Grau-Delgado, Lucía Zamora-Molina, Isabel Padilla-Navas, Eduardo García-Pachón
No abstract text is available yet for this article.
June 5, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28590236/interaction-between-the-new-world-begomovirus-euphorbia-yellow-mosaic-virus-and-its-associated-alphasatellite-effects-on-infection-and-transmission-by-the-whitefly-bemisia-tabaci
#16
Talita Bernardon Mar, Igor Rodrigues Mendes, Douglas Lau, Elvira Fiallo-Olivé, Jesús Navas-Castillo, Murilo Siqueira Alves, F Murilo Zerbini
The majority of Old World monopartite begomoviruses (family Geminiviridae) are associated with satellite DNAs. Alphasatellites are capable of autonomous replication, but depend on the helper virus for movement, encapsidation and transmission by the insect vector. Recently, Euphorbia yellow mosaic alphasatellite (EuYMA) was found in association with Euphorbia yellow mosaic virus (EuYMV) infecting Euphorbia heterophylla plants in Brazil. The geographical range of EuYMA was assessed in a representative sampling of E...
June 1, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28587079/immunomodulatory-effect-of-agave-tequilana-evaluated-on-an-autoimmunity-like-sle-model-induced-in-balb-c-mice-with-pristane
#17
Zúlima Jannette Gutiérrez Nava, Antonio Ruperto Jiménez-Aparicio, Maribel Lucila Herrera-Ruiz, Enrique Jiménez-Ferrer
In this work, the immunomodulatory activity of the acetone extract and the fructans obtained from Agave tequilana were evaluated, on the systemic autoimmunity type-SLE model generated by the administration of 2,6,10,14-tetramethylpentadecane (TMPD, also known as pristane) on Balb/c female mice. The systemic autoimmunity type-SLE was observed seven months after the application of TMPD, in which the animals from the negative control group (animals with damage and without any other treatment) developed articular inflammation, proteinuria, an increment of the antinuclear antibody titters and tissue pro-inflammatory cytokines levels (IL-1β, IL-6, TNF-α e IFN-γ) as well as the anti-inflammatory cytokine IL-10...
May 25, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28582531/biomarkers-of-secondhand-smoke-exposure-in-waterpipe-tobacco-venue-employees-in-istanbul-moscow-and-cairo
#18
Katherine A Moon, Ana M Rule, Hoda S Magid, Jacqueline Ferguson, Jolie Susan, Zhuolu Sun, Christine Torrey, Salahaddin Abubaker, Vladimir Levshin, Asli Çarkoglu, Ghada Nasr Radwan, Maha El-Rabbat, Joanna E Cohen, Paul Strickland, Patrick N Breysse, Ana Navas-Acien
Background: Most smoke-free legislation to reduce secondhand smoke (SHS) exposure exempts waterpipe (hookah) smoking venues. Few studies have examined SHS exposure in waterpipe venues and their employees. Methods: We surveyed 276 employees of 46 waterpipe tobacco venues in Istanbul, Moscow, and Cairo. We interviewed venue managers and employees and collected biological samples from employees to measure exhaled carbon monoxide (CO), hair nicotine, saliva cotinine, urine cotinine, urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and urine 1-hydroxypyrene glucuronide (1-OHPG)...
June 3, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28578708/effects-of-neurally-adjusted-ventilatory-assist-on-air-distribution-and-dead-space-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#19
Qin Sun, Ling Liu, Chun Pan, Zhanqi Zhao, Jingyuan Xu, Airan Liu, Haibo Qiu
BACKGROUND: Neurally adjusted ventilatory assist (NAVA) could improve patient-ventilator interaction; its effects on ventilation distribution and dead space are still unknown. The aim of this study was to evaluate the effects of varying levels of assist during NAVA and pressure support ventilation (PSV) on ventilation distribution and dead space in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). METHODS: Fifteen mechanically ventilated patients with AECOPD were included in the study...
June 2, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28576056/new-infrared-assisted-method-for-sol-gel-derived-zno-ag-thin-films-structural-and-bacterial-inhibition-properties
#20
Brenely González-Penguelly, Ángel de Jesús Morales-Ramírez, Miriam Guadalupe Rodríguez-Rosales, Celestino Odín Rodríguez-Nava, María Luz Carrera-Jota
A new sol-gel method, based on crystallization with Infrared heating, was developed to obtain ZnO:Ag thin films. The common sol, with zinc acetate as precursor and silver nitrate as doping source (1, 3 and 5 % molar), isopropanol and distilled water as solvents and monoethanolamine as stabilizer agent; was modified with Pluronic F127 and diethylene glycol as rheological agents, and with urea as fuel to produce enough energy to the combustion and to promote the crystallization process. Later, Corning glass-substrates were dipped into the sol at a constant speed of 3mms(-1)...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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