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https://www.readbyqxmd.com/read/28434196/role-of-gut-microbiota-bile-acids-and-their-crosstalk-in-the-effects-of-bariatric-surgery-on-obesity-and-type-2-diabetes
#1
Haijun Liu, Cheng Hu, Xueli Zhang, Weiping Jia
Type 2 diabetes mellitus is becoming increasingly prevalent worldwide and has become one of the greatest threats to global health. Bariatric surgery was initially designed to achieve weight loss and subsequently was noted to induce improvements or remission of type 2 diabetes. Currently, these bariatric operations such as Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the most effective procedures for the treatment of obesity and type 2 diabetes mellitus worldwide. However, the specific mechanism mediating the beneficial effects of metabolic surgery has remained largely unknown...
April 23, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28433465/dumping-symptoms-is-triggered-by-fat-as-well-as-carbohydrates-in-patients-operated-with-roux-en-y-gastric-bypass
#2
Anna Laurenius, Malin Werling, Carel W le Roux, Lars Fändriks, Torsten Olbers
BACKGROUND: Dumping syndrome after Roux-en-Y gastric bypass (RYGB) is traditionally associated with the consumption of refined carbohydrates, but the role of dietary fat is unclear. OBJECTIVES: This study compares symptoms after consumption of a carbohydrate-rich or fat-rich beverage to determine perceived symptoms, glycemic control, and pulse rate. SETTING: University hospital. METHODS: We assessed perceived symptoms (Sigstad's Dumping Index) and glycemic control (P-glucose and S-insulin) as well as autonomic nervous system activity (reflected by arterial pulse rate) after a standardized liquid meal test (440 kcal/300 mL carbohydrates [CARB] or fat [FAT]) in a randomized crossover blinded setting...
March 1, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28433464/electronic-synoptic-reporting-assessing-the-completeness-of-synoptic-and-narrative-reports-for-roux-en-y-gastric-bypass
#3
Ashley Vergis, Shannon E Stogryn, Michael J Mullan, Krista Hardy
BACKGROUND: Operative reporting is the foundation of surgical communication. The quality indicators (QIs) contained in these reports can be used to document the performance of processes that affect patient care and may afford quality assurance with improvement in healthcare. OBJECTIVES: We assessed the degree to which the electronic synoptic report (SR) documents the operative QIs compared with narrative reports (NR) for Roux-en-Y gastric bypass (RYGB). The time to report availability on patient chart was also identified as a secondary measure...
March 7, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28429199/gastric-bypass-and-influence-on-improvement-of-nafld
#4
REVIEW
Vamsi Alli, Ann M Rogers
PURPOSE OF REVIEW: Obesity is recognized as a chronic and recurring disease, often accompanied by other weight-related comorbid conditions such as obstructive sleep apnea, hypertension, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD). This chapter will seek to focus on the effect of weight loss surgery (WLS), in particular Roux-en-Y gastric bypass (RYGB), on NAFLD. RECENT FINDINGS: Among several modalities available to treat NAFLD, the one most likely to achieve rapid, significant, and sustained improvement of liver disease is WLS...
June 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28428706/gastroesophageal-reflux-disease-and-morbid-obesity-to-sleeve-or-not-to-sleeve
#5
EDITORIAL
Fabrizio Rebecchi, Marco E Allaix, Marco G Patti, Francisco Schlottmann, Mario Morino
Laparoscopic sleeve gastrectomy (LSG) has reached wide popularity during the last 15 years, due to the limited morbidity and mortality rates, and the very good weight loss results and effects on comorbid conditions. However, there are concerns regarding the effects of LSG on gastroesophageal reflux disease (GERD). The interpretation of the current evidence is challenged by the fact that the LSG technique is not standardized, and most studies investigate the presence of GERD by assessing symptoms and the use of acid reducing medications only...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28425683/preservation-of-duodenal-passage-as-a-determinant-of-short-and-long-term-quality-of-life-in-gastric-cancer-patients-after-total-gastrectomy
#6
Tomasz Olesiński, Marek Szpakowski, Piotr Saramak, Andrzej Rutkowski, Krzysztof Jeziorski
BACKGROUND: The aim of this prospective study was to compare subjective and objective quality of life (QoL) of gastric cancer patients after total gastrectomy with and without preservation of the duodenal passage during short- and long-term follow-up. METHODS: The study included 68 patients, among them 37 (54%) persons subjected to total gastrectomy with Roux-Y reconstruction (R-Y group) and 31 (46%) individuals in whom gastrectomy was followed by formation of Henley-Longmire loop (H-L group)...
April 19, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28422840/case-report-a-female-case-of-isolated-igg4-related-sclerosing-cholangitis-mimicking-cholangiocarcinoma
#7
Jianchun Xiao, Guanqiao Li, Gang Yang, Congwei Jia, Binglu Li
RATIONALE: IgG4-related disease is a newly recognized fibroinflammatory disorder, characterized by tumefactive lesions, storiform fibrosis and IgG4-positive plasma cells infiltration. IgG4-related sclerosing cholangitis (IgG4-SC) is the most common extrapancreatic manifestation of IgG4-related disease, but it is frequently associated with autoimmune pancreatitis(AIP). Only few case was reported to be diagnosed with IgG4-SC in the absence of AIP, with a striking male preponderance. Here we report a female case of isolated IgG4 related sclerosing cholangitis mimicking cholangiocarcinoma...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28421792/micronutrient-supplementation-in-gastric-bypass-surgery-prospective-study-on-in%C3%AF-ammation-and-iron-metabolism-in-premenopausal-women
#8
Flávia Andréia Marin, Rozangela Verlengia, Alex Harley Crisp, Patrícia Fátima Sousa Novais, Irineu Rasera-Junior, Maria Rita Marques De Oliveira
BACKGROUND: Low-grade chronic inflammation in morbid obesity is associated with impaired iron metabolism. Bariatric surgery is effective in weight loss; however, it can induce specific nutritional deficiencies, such as iron, especially in premenopausal women. Alternatively, after surgery, there is an improvement in systemic inflammation, raising questions concerning the dosages of micronutrient supplementation. OBJECTIVES: This study aimed to assess the effect of two micronutrient supplementation schemes before and 6 months after a Roux-en-Y gastric bypass (RYGB) surgery on inflammation and iron metabolism in premenopausal women...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28420586/impaired-oral-absorption-of-methylphenidate-after-roux-en-y-gastric-bypass
#9
REVIEW
Carmil Azran, Peter Langguth, Arik Dahan
The anatomic and physiologic changes in the gastrointestinal (GI) tract after bariatric surgery may significantly affect the pharmacokinetics of medications taken by the patients for various reasons. Unfortunately, there is little information regarding changes in drug absorption after bariatric surgeries, limiting the ability of medical professionals to produce clear recommendations on what changes should be made to the formulations and dosing regimens of drugs after bariatric surgery. In this article, we report and analyze a case of 52-year-old male patient with morbid obesity and attention-deficit/hyperactivity disorder (ADHD) who experienced lack of methylphenidate efficacy after Roux en-Y gastric bypass (RYGB), which was eventually resolved by using the transdermal patch instead of an oral product...
March 9, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28420040/semi-end-to-end-esophagojejunostomy-after-laparoscopy-assisted-total-gastrectomy-better-reduces-stricture-and-leakage-than-the-conventional-end-to-side-procedure-a-retrospective-study
#10
Wei Duan, Kaijun Liu, Xiaolong Fu, Xuqi Shen, Jun Chen, Chongyu Su, Peiwu Yu, Yongliang Zhao
BACKGROUND AND OBJECTIVE: Laparoscopy-assisted total gastrectomy (LATG) has not gained popularity due to the technical difficulty of esophagojejunostomy (EJ) and the high incidence of EJ-related complications. Herein, we compared two types of EJ for Roux-en-Y reconstruction to determine whether semi-end-to-end (SETE) EJ is more convenient than the end-to-side (ETS) procedure and is capable of reducing stricture and leakage. METHODS: A total of 268 patients who underwent LATG with Roux-en-Y reconstruction were included in this study...
April 18, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28419237/the-fat-score-a-fibrosis-score-of-adipose-tissue-predicting-weight-loss-outcome-after-gastric-bypass
#11
Pierre Bel Lassen, Frederic Charlotte, Yuejun Liu, Pierre Bedossa, Gilles le Naour, Joan Tordjman, Christine Poitou, Jean-Luc Bouillot, Laurent Genser, Jean-Daniel Zucker, Nataliya Sokolovska, Judith Aron-Wisnewsky, Karine Clément
Context: Bariatric surgery (BS) induces major and sustainable weight loss in many but not all patients. Factors predicting poor responders (PR) need to be identified to improve patient care. Quantification of subcutaneous adipose tissue (scAT) fibrosis is negatively associated with post-BS weight loss, but whether it could constitute a predictor applicable in clinical routine remains to be demonstrated. Objective: To create a semi-quantitative score evaluating scAT fibrosis and test its predictive value on weight loss response after Roux-en-Y gastric bypass (RYGB)...
April 17, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28416180/revision-of-sleeve-gastrectomy-to-roux-en-y-gastric-bypass-a-canadian-experience
#12
Ekua Yorke, Caroline Sheppard, Noah J Switzer, David Kim, Christopher de Gara, Shahzeer Karmali, Aliyah Kanji, Daniel Birch
INTRODUCTION: Sleeve gastrectomy (SG) can be associated with inadequate weight loss, insufficient resolution of co-morbidities and severe reflux. Conversion to Roux-en-Y Gastric Bypass (RYGB) is a potential solution. The aim of this study was to determine the common indications for conversion from SG to RYGB at our centre, and evaluate patient outcomes with respect to weight loss and co-morbidity resolution. METHODS: A retrospective review of patients who underwent conversion from SG to RYGB between 2008 and 2015...
April 8, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28415670/case-control-study-of-the-efficacy-of-retrogastric-roux-en-y-choledochojejunostomy
#13
Xin-Wei Yang, Jun-Yi Chen, Wen-Liang Yan, Jing Du, Zhi-Jian Wen, Xing-Zhou Yan, Ping-Hua Yang, Jue Yang, Bao-Hua Zhang
The traditional, retrocolic/antegastric Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications remains high. Here we report the outcome of 59 consecutively treated patients (study group, SG) that underwent a new choledochojejunostomy method in which the jejunal loop is passed behind the antrum pyloricum (retrogastric route). A retrospective comparison was made between this group of patients and 187 patients (control group, CG) that underwent conventional Roux-en-Y choledochojejunostomy (antegastric route)...
March 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28412539/laparoscopic-reoperative-anti-reflux-surgery-is-more-cost-effective-than-open-approach
#14
Farzaneh Banki, Matthew Weaver, David Roife, Chandni Kaushik, Anshu Khanna, Kelly Ochoa, Charles C Miller
BACKGROUND: We previously reported the outcomes of laparoscopic and open reoperative antireflux surgery. The aim of this study was to compare costs. METHODS: Retrospective review. Financial and procedure coding data were obtained using a cost accounting system. There were 49 procedures in 46 patients: 36 females/10 males. There were 38 laparoscopic (including 4 conversions); and 11 open procedures (7 transabdominal repairs and 4 gastric preserving Roux-en-Y esophagojejunostomy)...
April 12, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28411343/a-modified-uncut-roux-en-y-anastomosis-in-totally-laparoscopic-distal-gastrectomy-preliminary-results-and-initial-experience
#15
Jun-Jun Ma, Lu Zang, Annie Yang, Wei-Guo Hu, Bo Feng, Feng Dong, Ming-Liang Wang, Ai-Guo Lu, Jian-Wen Li, Min-Hua Zheng
OBJECTIVE: To investigate the safety and feasibility of totally laparoscopic uncut Roux-en-Y anastomosis in the distal gastrectomy with D2 dissection for gastric cancer. We also summarized the preliminary experience of totally laparoscopic uncut Roux-en-Y anastomosis. METHODS: A retrospective analysis was done in 51 cases of total laparoscopic uncut Roux-en-Y anastomosis in the distant gastrectomy with D2 dissection for gastric cancer in our hospital from September 2014 to December 2015...
April 14, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28411313/roux-en-y-gastric-bypass-and-sleeve-gastrectomy-does-not-affect-food-preferences-when-assessed-by-an-ad-libitum-buffet-meal
#16
Mette S Nielsen, Bodil J Christensen, Christian Ritz, Simone Rasmussen, Thea T Hansen, Wender L P Bredie, Carel W le Roux, Anders Sjödin, Julie B Schmidt
BACKGROUND: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) lead to a reduction in energy intake. It is uncertain whether this reduction is simply due to eating smaller portions or if surgery changes food preferences towards less energy-dense food. Previous results rely on verbal reports, which may be prone to recall bias and underestimation of especially unhealthy foods. METHODS: Using an ad libitum buffet meal targeting direct behavior, we investigated if RYGB and SG surgery leads to changes in food preferences...
April 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28411021/improvement-in-cardiovascular-risk-in-women-after-bariatric-surgery-as-measured-by-carotid-intima-media-thickness-comparison-of-sleeve-gastrectomy-versus-gastric-bypass
#17
Jesús M Gómez-Martin, Enrique Aracil, Julio Galindo, Héctor F Escobar-Morreale, José A Balsa, José I Botella-Carretero
BACKGROUND: Bariatric surgery may diminish cardiovascular risk (CVR) and its associated mortality. However, studies that compare these effects with different techniques are scarce. OBJECTIVE: To evaluate the changes in CVR as estimated by carotid intima-media thickness (IMT) after obesity surgery in women with high CVR as defined by the presence of metabolic syndrome. SETTING: Academic hospital. METHODS: We studied 40 severely obese women, of whom 20 received laparoscopic Roux en Y gastric bypass (RYGB) and 20 received sleeve gastrectomy (SG)...
February 3, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28405878/bariatric-surgery-and-endoluminal-procedures-ifso-worldwide-survey-2014
#18
L Angrisani, A Santonicola, P Iovino, A Vitiello, N Zundel, H Buchwald, N Scopinaro
BACKGROUND AND AIM: Several bariatric surgery worldwide surveys have been previously published to illustrate the evolution of bariatric surgery in the last decades. The aim of this survey is to report an updated overview of all bariatric procedures performed in 2014.For the first time, a special section on endoluminal techniques was added. METHODS: The 2014 International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) survey form evaluating the number and the type of surgical and endoluminal bariatric procedures was emailed to all IFSO societies...
April 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28405877/revision-roux-en-y-gastric-bypass-to-biliopancreatic-long-limb-gastric-bypass-for-inadequate-weight-response-case-series-and-analysis
#19
Henry Buchwald, Danette M Oien
BACKGROUND: The long-limb Roux-en-Y gastric bypass (LLRYGB) was introduced in 1987 as a salvage operation for inadequate weight loss after a standard Roux-en-Y gastric bypass (RYGB). METHODS: We report on 53 consecutive patients (44 females) with conversion of a failed RYGB to a LLRYGB performed by a single surgeon between 2002 and 2014. No patient had an ascertainable anatomic abnormality to explain his/her weight regain. LLRYGB revision consisted of a 75-cm to 100-cm alimentary Roux limb and a 75-cm to 100-cm common channel; after 2011, in suitable patients, the Roux limb was lengthened to greater than 250 cm...
April 12, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28403093/jejunojejunal-intussusception-after-roux-en-y-gastric-bypass-in-a-situs-inversus-totalis-patient-a-case-report
#20
Guangyi Jiang, Baojuan Fu, Sheng Lv, Junjie Hong, Xiujun Cai
INTRODUCTION: Situs inversus totalis (SIT) is an uncommon clinical manifestation. Patients with SIT typically have malformation in the thorax and abdomen. The incidence of SIT ranges from 1/10,000 to 1/20,000 (Al-Jumaily and Hoche. J Laparoendosc Adv Surg Tech A 2001;11:229). Jejunojejunal intussusception is a rare complication after Roux-en-Y gastric bypass. Intussusception in adult cases accounts for 5% of adult intestinal obstruction cases, while in children, the occurrence is high and the majority of them are idiopathic cases...
April 2017: Medicine (Baltimore)
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