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https://www.readbyqxmd.com/read/29352738/persistent-pain-following-common-outpatient-surgeries-in-children-a-multicenter-study-in-italy
#1
Valeria Mossetti, Karen Boretsky, Marinella Astuto, Bruno G Locatelli, David Zurakowski, Rodolfo Lio, Roberta Nicoletti, Valter Sonzogni, Micol Maffioletti, Noemi Vicchio, Giorgio Ivani
INTRODUCTION: The prevalence of persistent postsurgical pain in children is over 20% after major surgeries; however, data are scarce on the prevalence, character, and risk factors among children undergoing common ambulatory surgeries. The primary aim of this study was to evaluate the prevalence of persistent pain following pediatric ambulatory surgery at 1, 3, and 6 months. Secondary aims were to identify risk factors and characterize the pain and consequences of persistent postsurgical pain...
January 20, 2018: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29352678/e-bike-related-trauma-in-children-and-adults
#2
Itai Gross, Daniel J Weiss, Elior Eliasi, Miklosh Bala, Saar Hashavya
BACKGROUND: Electric bike (e-bike) usage is growing worldwide, and so is the e-bike-related injury rate. OBJECTIVE: This study was undertaken to characterize e-bike-related injuries. METHODS: Data of all e-bike-related injuries presenting to our level I trauma center between 2014 and 2016 were collected and analyzed. Adult and pediatric (<18 years of age) e-bike-related injuries were then analyzed separately and compared. RESULTS: Forty-eight patients suffering from e-bike-related injuries presented to our trauma center between January 1, 2014 and December 31, 2016...
January 15, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29352665/complementary-and-alternative-medicine-cam-practices-and-dietary-patterns-in-children-with-inflammatory-bowel-disease-in-singapore-and-malaysia
#3
Fangyi Ong, Way Seah Lee, Charlotte Lin, Ruey Terng Ng, Shin Yee Wong, Su Lin Lim, Seng Hock Quak, Marion Aw
BACKGROUND: The use of complementary and alternative medicine (CAM) has been associated with adverse effects and self-imposed dietary restrictions. The prevalence of its use in Asian children with inflammatory bowel disease (IBD) is unknown. We aimed to determine the prevalence, types, and factors associated with the use of CAM among children with IBD from Singapore and Malaysia, and to ascertain if dietary restriction was prevalent in patients who used CAM. METHODS: A cross-sectional study was conducted in which parents of children with IBD attending two tertiary pediatric IBD referral centres in Singapore and Malaysia were interviewed...
December 26, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29352663/early-versus-delayed-closure-of-bladder-exstrophy-a-national-surgical-quality-improvement-program-pediatric-analysis
#4
J J Ahn, M Shnorhavorian, C Katz, A B Goldin, P A Merguerian
INTRODUCTION: Delayed closure of bladder exstrophy has become more popular; however, there is limited the evidence of its success. Existing literature focuses on intermediate and long-term outcomes, and short-term postoperative outcomes are limited by the small number of cases and varying follow-up methods. OBJECTIVE: The objectives of the current study were to: 1) compare 30-day complications after early and delayed closure of bladder exstrophy, and 2) evaluate practice patterns of bladder exstrophy closure...
December 15, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29352592/development-and-validation-of-an-icd-10-based-disability-predictive-index-for-patients-admitted-to-hospitals-with-trauma
#5
Tomoki Wada, Hideo Yasunaga, Hayato Yamana, Hiroki Matsui, Kiyohide Fushimi, Naoto Morimura
BACKGROUND: There was no established disability predictive measurement for patients with trauma that could be used in administrative claims databases. The aim of the present study was to develop and validate a diagnosis-based disability predictive index for severe physical disability at discharge using the International Classification of Diseases, 10th revision (ICD-10) coding. METHODS: This retrospective observational study used the Diagnosis Procedure Combination database in Japan...
December 28, 2017: Injury
https://www.readbyqxmd.com/read/29352590/allergic-proctocolitis-is-a-risk-factor-for-functional-gastrointestinal-disorders-in-children
#6
Giovanni Di Nardo, Cesare Cremon, Simone Frediani, Sandra Lucarelli, Maria Pia Villa, Vincenzo Stanghellini, Giuseppe La Torre, Luigi Martemucci, Giovanni Barbara
OBJECTIVE: To test the hypothesis that allergic proctocolitis, a cause of self-limiting rectal bleeding in infants, can predispose to the development of functional gastrointestinal disorders (FGIDs) later in childhood. STUDY DESIGN: We studied a cohort of 80 consecutive patients diagnosed with allergic proctocolitis. Their sibling or matched children presenting to the same hospital for minor trauma served as controls. Parents of the patients with allergic proctocolitis and controls participated in a telephone interview every 12 months until the child was at least 4 years old...
January 15, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29352516/successful-hematopoietic-cell-transplantation-following-cardiac-transplantation-in-two-pediatric-patients
#7
Rachel Phelan, Angela R Smith, Paul J Orchard, Rebecca K Ameduri
We report two patients who underwent cardiac transplantation at a young age and subsequently required a HCT for varied indications. Despite the challenges associated with HCT following cardiac transplant, including need for altered immunosuppression, toxicities related to chemotherapy exposure, and infection risks, both patients are currently alive and well. There is a paucity of such successful cases documented in the literature, and these cases highlight the critical importance of an experienced, multidisciplinary team when caring for this patient population...
January 19, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29352455/clinical-features-in-a-series-of-258-japanese-pediatric-patients-with-thrombotic-microangiopathy
#8
Akira Ashida, Hideki Matsumura, Toshihiro Sawai, Rika Fujimaru, Yuko Fujii, Akihiko Shirasu, Hyogo Nakakura, Kazumoto Iijima
BACKGROUND: Thrombotic microangiopathy (TMA) includes hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). This study examined the epidemiological characteristics of pediatric patients with TMA classified according to etiology. METHODS: The survey evaluated 258 Japanese pediatric patients diagnosed with TMA between 2012 and 2015. RESULTS: The primary diseases responsible for TMA were categorized as TTP (15 cases), Shiga toxin-producing Escherichia coli-associated HUS (STEC-HUS) (166 cases), atypical HUS (aHUS) (40 cases), and secondary TMA (27 cases)...
January 19, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29352447/long-term-endocrine-effects-and-trends-in-body-mass-index-changes-in-patients-with-childhood-onset-brain-tumors
#9
Go Hun Seo, Jin-Ho Choi, Yoon-Myung Kim, Kyung-Nam Koh, Ho Joon Im, Young Shin Ra, Han-Wook Yoo
As survival rates have improved owing to advances in management strategies for pediatric brain tumors, long-term complications such as endocrine dysfunction, have emerged as a major issue. This study investigated the long-term endocrine effects of childhood-onset brain tumors in a large number of patients. This study included 151 patients with brain tumors diagnosed between January 1995 and December 2016. The following data were retrospectively reviewed: tumor location, tumor histology, endocrine abnormalities, hypothalamic involvement on brain imaging, treatment modalities, and trends in body mass index...
January 19, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29352416/point-of-care-ultrasound-in-pediatric-anesthesiology-and-critical-care-medicine
#10
REVIEW
Erik Su, Nicholas Dalesio, Aliaksei Pustavoitau
Ultrasound has increasingly become a clinical asset in the hands of the anesthesiologist and intensivist who cares for children. Though many applications for ultrasound parallel adult modalities, children as always are not simply small adults and benefit from the application of ultrasound to their management in various ways. Body composition and size are important factors that affect ultrasound performance in the child, as are the pathologies that may uniquely afflict children and aspects of procedures unique to this patient population...
January 19, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29352084/detection-of-human-bocavirus-species-2-and-3-in-bivalve-shellfish-in-italy
#11
G La Rosa, G Purpari, A Guercio, S Di Bella, F Gucciardi, Y T R Proroga, M Pisanu, S Della Libera, M Iaconelli, E Suffredini
Human bocavirus (HBoV) has been shown to be a common cause of respiratory infections and gastroenteritis in children. Recently, HBoVs have been detected in sewage and river waters in Italy and worldwide. However, no studies are yet available on their presence in other water environments and in bivalve molluscs.In this study, 316 bivalve shellfish samples collected in three Italian regions over a six-year period (2012-2017) were analyzed by nested PCR and sequencing using broad-range primer pairs targeting the capsid proteins VP1/VP2 of HBoV...
January 19, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29352018/oncohistones-drivers-of-pediatric-cancers
#12
REVIEW
Faizaan Mohammad, Kristian Helin
One of the most striking results in the area of chromatin and cancer in recent years has been the identification of recurrent mutations in histone genes in pediatric cancers. These mutations occur at high frequency and lead to the expression of mutant histones that exhibit oncogenic features. Thus, they are termed oncohistones. Thus far, mutations have been found in the genes encoding histone H3 and its variants. The expression of the oncohistones affects the global chromatin landscape through mechanisms that have just begun to be unraveled...
December 1, 2017: Genes & Development
https://www.readbyqxmd.com/read/29351866/bioanalysis-of-a-panel-of-neurotransmitters-and-their-metabolites-in-plasma-samples-obtained-from-pediatric-patients-with-neuroblastoma-and-wilms-tumor
#13
Lucyna Konieczna, Anna Roszkowska, Teresa Stachowicz-Stencel, Anna Synakiewicz, Tomasz Bączek
This paper details the quantitative analysis of neurotransmitters, including dopamine (DA), norepinephrine (NE), epinephrine (E), and serotonin (5-HT), along with their respective precursors and metabolites in children with solid tumors: Wilms' tumor (WT) and neuroblastoma (NB). A panel of neurotransmitters was determined with the use of dispersive liquid-liquid microextraction (DLLME) technique combined with liquid-chromatography mass spectrometry (LC-MS/MS) in plasma samples obtained from a group of pediatric subjects with solid tumors and a control group of healthy children...
December 28, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29351827/nocturnal-rem-sleep-without-atonia-is-a-diagnostic-biomarker-of-pediatric-narcolepsy
#14
Saadoun Bin-Hasan, Aleksandar Videnovic, Kiran Maski
STUDY OBJECTIVES: Compare nocturnal REM sleep without atonia (nRWA) and REM sleep behavior disorder (RBD) between pediatric patients with and without narcolepsy and determine if the nRWA index is a valid diagnostic biomarker for narcolepsy. METHODS: Retrospective cohort study of children ages 6 to 18 years who completed a nocturnal polysomnogram (PSG) and Multiple Sleep Latency Test (MSLT). Our study sample included 11 patients with narcolepsy type 1 (NT1), 6 with narcolepsy type 2 (NT2), 12 with idiopathic hypersomnia (IH), and 11 with subjective hypersomnia (sHS)...
January 16, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29351811/rate-and-determinants-of-non-adherence-to-a-gluten-free-diet-and-nutritional-status-assessment-in-children-and-adolescents-with-celiac-disease-in-a-tertiary-brazilian-referral-center-a-cross-sectional-and-retrospective-study
#15
Maraci Rodrigues, Glauce Hiromi Yonaminez, Carla Aline Satiro
BACKGROUND: Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treatment of patients with celiac disease and give support to their parents plays a special role on strengthening GFD and assessing the nutritional and physical health. METHODS: A cross-sectional and retrospective study including patients under 20 years of age, with biopsy-confirmed CD, followed regularly at the Department of Pediatrics, Division of Gastroenterology, Hospital das Clínicas, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil, were surveyed using a questionnaire and serologic test applied between November 2011 and February 2012...
January 19, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29351738/oscillometric-blood-pressure-by-age-and-height-for-non-overweight-children-and-adolescents-in-lubumbashi-democratic-republic-of-congo
#16
Emmanuel Kiyana Muyumba, Dophra Ngoy Nkulu, Clarence Kaut Mukeng, Jacques Mbaz Musung, Placide Kambola Kakoma, Christian Ngama Kakisingi, Oscar Numbi Luboya, Françoise Kaj Malonga, Justin Kalungwe Kizonde, Olivier Mukuku, Weili Yan
BACKGROUND: The diagnosis of hypertension in children is complex because based on normative values by sex, age and height, and these values vary depending on the environment. Available BP references used, because of the absence of local data, do not correspond to our pediatric population. Accordingly, our study aimed to provide the BP threshold for children and adolescents in Lubumbashi (DRC) and to compare them with German (KIGGS study), Polish (OLAF study) and Chinese (CHNS study) references...
January 19, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29351642/caregiver-provided-physical-therapy-home-programs-for-children-with-motor-delay-a-scoping-review
#17
Edward James R Gorgon
Background: Caregiver-provided physical therapy home programs (PTHP) play an important role in enhancing motor outcomes in pediatric patient populations. Purpose: This scoping review systematically mapped clinical trials of caregiver-provided PTHP that were aimed at enhancing motor outcomes in children who have or who are at risk for motor delay, with the purpose of (1) describing trial characteristics; (2) assessing methodologic quality, and (3) examining the reporting of caregiver-related components...
January 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29351636/effectiveness-of-respiratory-syncytial-virus-immunoprophylaxis-on-bronchiolitis-hospitalizations-among-high-risk-infants
#18
Pingsheng Wu, Gabriel J Escobar, Tebeb Gebretsadik, Kecia N Carroll, Sherian X Li, Eileen M Walsh, Edward F Mitchel, Chantel Sloan, William D Dupont, Chang Yu, Jeffrey R Horner, Tina V Hartert
We sought to determine the real-world effectiveness of respiratory syncytial virus (RSV) immunoprophylaxis in a population-based cohort to inform policy. The study population included infants born 1996-2008 and enrolled in Kaiser Permanente Northern California. During the RSV season (November-March), RSV immunoprophylaxis administration and the following 30 days were defined as RSV immunoprophylaxis protected period(s), and all other days as unprotected period(s). Bronchiolitis hospitalizations were determined using the International Classification of Diseases Ninth Revision codes during RSV season...
January 17, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29351501/pediatric-anaphylaxis-in-the-prehospital-setting-incidence-characteristics-and-management
#19
Emily Andrew, Ziad Nehme, Stephen Bernard, Karen Smith
OBJECTIVE: Although hospital presentations for pediatric anaphylaxis have been described in the literature, a minimal amount is known regarding the incidence, characteristics, and management of pediatric anaphylaxis presenting to emergency medical services (EMS). METHODS: We performed a retrospective observational study of pediatrics (≤16 years) presenting to EMS in Victoria, Australia. Patients with suspected anaphylaxis were included if they were treated with epinephrine before or after EMS arrival...
January 19, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29351496/implementation-of-a-prehospital-protocol-change-for-asthmatic-children
#20
Anriada Nassif, Daniel G Ostermayer, Kim B Hoang, Mary K Claiborne, Elizabeth A Camp, Manish I Shah
BACKGROUND: Respiratory distress due to asthma is a common reason for pediatric emergency medical services (EMS) transports. Timely initiation of asthma treatment, including glucocorticoids, improves hospital outcomes. The impact of EMS-administered glucocorticoids on hospital-based outcomes for pediatric asthma patients is unknown. OBJECTIVE: The objective of this study was to evaluate the effect of an evidence-based pediatric EMS asthma protocol update, inclusive of oral glucocorticoid administration, on time to hospital discharge...
January 19, 2018: Prehospital Emergency Care
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