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Mva stroke

Darae Kim, Hyemoon Chung, Jong Ho Nam, Dong Hyuk Park, Chi Young Shim, Jung Sun Kim, Hyuk Jae Chang, Geu Ru Hong, Jong Won Ha
PURPOSE: We determined factors associated with long-term outcomes of patients who underwent successful percutaneous mitral balloon valvuloplasty (PMV). MATERIALS AND METHODS: Between August 1980 and May 2013, 1187 patients underwent PMV at Severance Hospital, Seoul, Korea. A total of 742 patients who underwent regular clinic visits for more than 10 years were retrospectively analyzed. The endpoints consisted of repeated PMV, mitral valve (MV) surgery, and cardiovascular-related death...
March 2018: Yonsei Medical Journal
Anna Fracassi, Martina Marangoni, Pamela Rosso, Valentina Pallottini, Marco Fioramonti, Silvia Siteni, Marco Segatto
BACKGROUND: Statins represent a class of medications widely prescribed to efficiently treat dyslipidemia. These drugs inhibit 3-βhydroxy 3β-methylglutaryl Coenzyme A reductase (HMGR), the rate-limiting enzyme of mevalonate (MVA) pathway. Besides cholesterol, MVA pathway leads to the production of several other compounds, which are essential in the regulation of a plethora of biological activities, including in the central nervous system. For these reasons, statins are able to induce pleiotropic actions, and acquire increased interest as potential and novel modulators in brain processes, especially during pathological conditions...
July 3, 2017: Current Neuropharmacology
Atoosheh Rohani, Hoorak Poorzand, Mohammad R Arefifar
Atrial fibrillation (AF), left atrial appendage thrombi (LAAT) and subsequent embolic stroke are the most frequent complications of mitral stenosis .E/Ea is used traditionally for the assessment of left atrium pressure, and besides AF and dilated LA size which promotes stasis of blood in LA, high LA pressure also play a role to clot formation in LA .The receiver operator characteristics (ROC) curve point-coordinates identified an E:e' value of ≥ 36.5to have 57.14% sensitivity and 90.91% specificity for LAAT;We find this ratio relatively specific for prediction of LAAT, independent of MVA and LA volume, however it needs to be externally validated...
October 2016: Journal of Atrial Fibrillation
Natalia Yuriivna Osovska, Natalia Vitaliivna Kuzminova
Stable angina is the most frequent manifestation of ischemic heart disease (IHD) in women as compared to men (65% versus 37%). IHD in women has more favorable clinical course because myocardial infarction develops twice as rare as in men. Coronary angiography of angina patients demonstrates normal coronary arteries more frequently in women than in men. Microvascular angina (MVA) is found to be a rather common form of stable IHD as that particular diagnosis is made later in 20-30% of patients who previously underwent coronary angiography...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Jacob Levman, Emi Takahashi
Brain cancer and neurological injuries, such as stroke, are life-threatening conditions for which further research is needed to overcome the many challenges associated with providing optimal patient care. Multivariate analysis (MVA) is a class of pattern recognition technique involving the processing of data that contains multiple measurements per sample. MVA can be used to address a wide variety of neuroimaging challenges, including identifying variables associated with patient outcomes; understanding an injury's etiology, development, and progression; creating diagnostic tests; assisting in treatment monitoring; and more...
2016: Frontiers in Pediatrics
Axel R Pries, Bettina Reglin
Coronary microvascular networks play the key role in determining blood flow distribution in the heart. Matching local blood supply to tissue metabolic demand entails continuous adaptation of coronary vessels via regulation of smooth muscle tone and structural dilated vessel diameter. The importance of coronary microcirculation for relevant pathological conditions including angina in patients with normal or near-normal coronary angiograms [microvascular angina (MVA)] and heart failure with preserved ejection fraction (HFpEF) is increasingly recognized...
February 14, 2017: European Heart Journal
Alaa Mabrouk Salem Omar, Mohamed Ahmed Abdel-Rahman, Hala Raslan, Osama Rifaie
BACKGROUND: Echocardiographic assessment of left atrial pressure (LAP) in mitral stenosis (MS) is controversial. We sought to examine the role of the radius of the proximal isovelocity surface area (PISA-r) in the assessment of the hemodynamic status of MS after fixing the aliasing velocity (Val). METHODS AND RESULTS: We studied 42 candidates of balloon mitral valvuloplasty (BMV), for whom pre-BMV echocardiography was done and LAP invasively measured before dilatation...
October 2015: Journal of the Saudi Heart Association
V Murugesan, V K Pulimamidi, M Rajappa, S Satheesh, G Revathy, K T Harichandrakumari
Mitral stenosis (MS) causes stagnation of blood flow, leading to thrombus formation in the left atrium (LA), which may lead to systemic thrombo-embolic complications and stroke. We compared the alterations in echocardiographic and procoagulant parameters in patients with severe rheumatic MS with and without LA thrombus. The study was a cross-sectional study of patients with rheumatic MS, being evaluated for percutaneous mitral commisurotomy. Group 1 patients comprised of patients with rheumatic MS with LA thrombus (n=35) and Group 2 patients had rheumatic MS without LA thrombus (n = 45)...
2015: British Journal of Biomedical Science
Nahid Salehi, Mohammadreza Saidi, Alireza Rai, Farid Najafi, Seedmokhtar Javeedannejad, Mehran Babanejad, Hooman Tadbiri
BACKGROUND: There is considerable disagreement over the effects of percutaneous coronary intervention (PCI) on left ventricular diastolic function that has necessitated the investigation of diastolic indices. The present study was conducted to evaluate left ventricular diastolic function and its indices, three months after performing the PCI procedure in patients with coronary artery disease (CAD). METHODS: In a quasi-experimental clinical trial study (before and after), 51 patients with CAD scheduled for elective PCI were investigated provided that their Ejection Fraction (EF) was > 30%...
2016: Global Journal of Health Science
Holly Mansell, Hamdi Elmoselhi, Ahmed Shoker
BACKGROUND/AIMS: The 7-year Major Adverse Cardiovascular Events Calculator (CRCRTR-MACE) predicts cardiovascular events (CVE) in renal transplant recipients (RTR), and thrombopoietin (TPO) is a humoral inflammatory factor implicated in cardiovascular disease (CVD). The aim of the study was to determine if circulating TPO levels in stable RTR are positively associated with variable(s) in the CRCRTR-MACE score. METHODS: CRCRTR-MACE scores were calculated in 95 stable RTR...
2015: American Journal of Nephrology
Mai Iwataki, Masaaki Takeuchi, Kyoko Otani, Hiroshi Kuwaki, Hidetoshi Yoshitani, Haruhiko Abe, Roberto M Lang, Robert A Levine, Yutaka Otsuji
OBJECTIVE: Mitral annular/leaflet calcification (MALC) is frequently observed in patients with degenerative aortic stenosis (AS). However, the impact of MALC on mitral valve function has not been established. We aimed to investigate whether MALC reduces mitral annular area and restricts leaflet opening, resulting in non-rheumatic mitral stenosis. METHODS: Real-time three-dimensional transoesophageal images of the mitral valve were acquired in 101 patients with degenerative AS and 26 control participants...
2014: Open Heart
Wei-Guang Zhang, Shu-Ying Zhu, De-Long Zhao, Shi-Min Jiang, Juan Li, Zuo-Xiang Li, Bo Fu, Min Zhang, Dian-Geng Li, Xiao-Juan Bai, Guang-Yan Cai, Xue-Feng Sun, Xiang-Mei Chen
OBJECTIVES: To investigate the relationship between telomere length in peripheral blood white cells and cardiovascular function in a healthy, aging Han Chinese population. METHODS: In 2012, peripheral blood leukocytes were obtained from 139 healthy individuals in Beijing, China, and telomere restriction fragment (TRF) length was assayed using a digoxigenin-labeled hybridization probe in Southern blot assays. Indicators of cardiovascular function were also evaluated, including electrocardiograms (ECG), (RR, P, PR, QRS, ST and T intervals); blood pressure (BP), (SBP, DBP, PP, PPI); cardiovascular ultrasound (left ventricular ejection fraction, LVEF); mitral early and late diastolic peak flow velocity (MVE and MVA); and lipid indices (TC, TG, HDL, LDL, LCI)...
September 2014: Heart, Lung & Circulation
Mohammed Fakhry Abdul-Mohsen
BACKGROUND AND OBJECTIVES: Sickle cell disease (SCD) is a chronic, inherited haemoglobin disorder, associated with recurrent vaso-occlusive and haemolytic crises and chronic tissue ischemia which may adversely affect any organ system. Our objectives were to evaluate the left ventricular (LV) systolic and diastolic functions in Saudi patients with SCD originally from the Eastern Province of Saudi Arabia. DESIGN AND SETTING: Prospective hospital based echocardiography study on adolescent and adult patients with SCD...
October 2012: Journal of the Saudi Heart Association
Kavian Ghandehari, Mohammad Reza Khajedaluei, Zahra Yazdankhah, Kosar Ghandehari
BACKGROUND: Assessing the risk of recurrent ischemic events in patients with transient ischemic attack (TIA) and minor ischemic stroke (MIS) is of a great importance in clinical practice. METHODS: Consecutive patients with TIA or MIS who were visited in Ghaem Hospital, (Mashhad, Iran) were enrolled in a prospective cohort study during 2010 to 2011. Diagnosis of TIA or MIS was accomplished by a stroke neurologist. Only those who presented within 24 hours from the onset of symptoms were recruited...
March 2013: ARYA Atherosclerosis
Sun-Yang Min, Jong-Min Song, Yun-Jeong Kim, Hong-Kyung Park, Mi-Ohk Seo, Moo-Song Lee, Dae-Hee Kim, Duk-Hyun Kang, Jae-Kwan Song
OBJECTIVE: To compare mitral valve area (MVA) measurements obtained by 2D transthoracic planimetry and 3D transoesophageal echocardiography (TOE) in patients with mitral stenosis (MS), and to determine the causes of discrepancies between the two techniques. DESIGN: Reliability and agreement study. SETTING: Tertiary referral centre. PATIENTS: Eighty-seven patients with MS. METHODS: MVA was determined by transthoracic 2D planimetry and 3D TOE...
February 2013: Heart: Official Journal of the British Cardiac Society
Murat Yuce, Vedat Davutoglu, Cayan Akkoyun, Nese Kizilkan, Suleyman Ercan, Murat Akcay, Ibrahim Sari
BACKGROUND AND AIM OF THE STUDY: Interatrial block (IAB), a frequently overlooked conduction delay between the atria, is defined as prolonged P-wave on the electrocardiogram (ECG). Previously, IAB has been shown to be an indicator of dilated and impaired left atrial function, and a predictor of both atrial fibrillation and embolic stroke. The study aim was to test the hypothesis that, on ECG, IAB with P-terminal force can reflect the echocardiographic severity of mitral stenosis (MS)...
November 2011: Journal of Heart Valve Disease
Liang Zhong, Lay Kheng Tan, Chris J Finn, Dhanjoo Ghista, Reginald Liew, Zee Pin Ding
INTRODUCTION: This study was carried out to (i) provide the methodology for determining left atrial (LA) volume, emptying fraction and ejection force (LAEF), from real-time 3-dimensional echocardiography (RT3DE), and (ii) evaluate the effects of age and gender on LA volume and LAEF in a wide age range of healthy participants. MATERIALS AND METHODS: RT3DE was performed in 102 healthy participants (age range, 20 to 80 years). From full-volume data sets, LA endocardial borders were automatically traced and LA volumes were determined...
April 2012: Annals of the Academy of Medicine, Singapore
Hunaid A Vohra, Robert N Whistance, Laurynas Bezuska, Steve A Livesey
OBJECTIVE: The Carpentier-Edwards (CE) Physio II ring is a new prosthetic ring designed to accommodate the changing pathology seen in the spectrum of degenerative valve disease, particularly the larger anterior leaflet in repair of the Barlow valve. The aim of our study was to assess the safety and efficacy of mitral valve (MV) repair with the CE Physio II ring. METHODS: Between April 2009 and March 2010, 100 patients underwent MV repair using the Physio II ring...
June 2011: European Journal of Cardio-thoracic Surgery
Hans Henrik Odland, Grete Anette Birkeland Kro, Berit H Munkeby, Thor Edvardsen, Ola Didrik Saugstad, Erik Thaulow
This study aimed to assess the effect of correcting for the impact of heart rate (HR) or ejection time (ET) on myocardial velocities in the long axis in piglets undergoing hypoxia. The ability to eject a higher volume at a fixed ET is a characteristic of contractility in the heart. Systolic velocity of the atrioventricular annulus displacement is directly related to volume changes of the ventricle. Both ET and systolic velocity may be measured in a single heartbeat. In 29 neonatal pigs, systolic velocity and ET were measured with tissue Doppler techniques in the mitral valve annulus, the tricuspid valve annulus, and the septum...
October 2010: Pediatric Cardiology
Peter Y K Hwang, Philip M Lewis, Yagnesh V Balasubramani, Anoop Madan, Jeffrey V Rosenfeld
BACKGROUND: Blunt carotid and vertebral artery injury (BCVI) is a relatively uncommon but potentially devastating injury. The aim of our study was to highlight the incidence, patterns, presentation and associations of BCVI at our institution. METHODS: Retrospective data between 1st January 2003 and 31st December 2006 was obtained from The Alfred Hospital's health information system, patient medical records and the Department of Neurosurgery's database. Injuries were graded using the Denver grading scale...
September 2010: Injury
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