keyword
MENU ▼
Read by QxMD icon Read
search

Breast cancer and microcalcification

keyword
https://www.readbyqxmd.com/read/28436856/task-based-modeling-of-an-5k-ultra-high-resolution-medical-imaging-system-for-digital-breast-tomosynthesis
#1
Chumin Zhao, Jerzy Kanicki
High-resolution, low noise x-ray detectors based on CMOS active pixel sensor (APS) technology have demonstrated superior imaging performance for digital breast tomosynthesis (DBT). This paper presents a task-based model for a high resolution medical imaging system to evaluate its ability to detect simulated microcalcifications and masses as lesions for breast cancer. Three-dimensional (3D) cascaded system analysis for a 50 μm pixel pitch CMOS APS x-ray detector was integrated with an object task function, a medical imaging display model, and the human eye contrast sensitivity function to calculate the detectability index and area under the ROC curve (AUC)...
April 19, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28420325/usefulness-of-grayscale-inverted-images-in-addition-to-standard-images-in-digital-mammography
#2
Ayşegül Altunkeser, M Kazım Körez
BACKGROUND: Mammography is essential for early diagnosis of breast cancer, which is the most common type of cancer in females that is associated with a high mortality rate. We investigated whether evaluation of the grayscale inverted images of mammograms would aid in increasing the diagnostic sensitivity of the mammographic imaging technique. METHODS: Our study included 636 mammograms of 159 women who had undergone digital mammography. Standard, grayscale inverted, and standard plus grayscale inverted images were sequentially examined three times, at 15-day intervals, for the presence or assessment of pathological changes in the skin, calcification, asymmetric density, mass lesions, structural distortions, and intramammary and axillary lymph nodes...
April 18, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28415815/bi-rads-3-5-microcalcifications-prediction-of-lymph-node-metastasis-of-breast-cancer
#3
Dongzhi Cen, Li Xu, Siwei Zhang, Shuqin Zhou, Yan Huang, Zhiguang Chen, Ningna Li, Yuan Wang, Qun Wang
PURPOSE: To determine whether the clinicopathological parameters and Breast Imaging Reporting and Data System (BI-RADS) 3-5 microcalcifications differed between lymph node positive (LN (+)) and lymph node negative (LN (-)) invasive ductal carcinoma (IDC). RESULTS: For microcalcification-associated breast cancers, seven selected features (age, tumor size, Ki-67 status, lymphovascular invasion, calcification range, calcification diameter and calcification density) were significantly associated with LN status (all P < 0...
March 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28357084/sclerosing-adenosis-ultrasonographic-and-mammographic-findings-and-correlation-with-histopathology
#4
Ya-Ling Chen, Jia-Jian Chen, Cai Chang, Yi Gao, Jiong Wu, Wen-Tao Yang, Ya-Jia Gu
The present study was conducted to evaluate the radiological findings, particularly the ultrasonographic (US) characteristics of sclerosing adenosis (SA), and their correlation with histopathological results. A retrospective review identified 191 patients with a total of 200 lesions histopathologically confirmed as SA following breast surgery between July 2009 and December 2012. Of the 191 patients, 145 (151 lesions) with SA as the major component were included for US and mammographic (MG) analysis. All 145 patients analyzed were female, with a mean age ± standard deviation of 46...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28332199/investigating-the-feasibility-of-classifying-breast-microcalcifications-using-photon-counting-spectral-mammography-a-simulation-study
#5
Bahaa Ghammraoui, Stephen J Glick
PURPOSE: A dual-energy material decomposition method using photon-counting spectral mammography was investigated as a non-invasive diagnostic approach to differentiate between Type I calcifications, consisting of calcium oxalate dihydrate or weddellite compounds that are more often associated with benign lesions, and Type II calcifications containing hydroxyapatite that are predominantly associated with malignant tumors. METHODS: The study was carried out by numerical simulation to assess the feasibility of the proposed approach...
March 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28288659/a-clinical-model-for-identifying-the-short-term-risk-of-breast-cancer
#6
Mikael Eriksson, Kamila Czene, Yudi Pawitan, Karin Leifland, Hatef Darabi, Per Hall
BACKGROUND: Most mammography screening programs are not individualized. To efficiently screen for breast cancer, the individual risk of the disease should be determined. We describe a model that could be used at most mammography screening units without adding substantial cost. METHODS: The study was based on the Karma cohort, which included 70,877 participants. Mammograms were collected up to 3 years following the baseline mammogram. A prediction protocol was developed using mammographic density, computer-aided detection of microcalcifications and masses, use of hormone replacement therapy (HRT), family history of breast cancer, menopausal status, age, and body mass index...
March 14, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28284000/a-method-for-microcalcifications-detection-in-breast-mammograms
#7
Abbas H Hassin Alasadi, Ahmed Kadem Hamed Al-Saedi
Breast cancer is the most cause of death for women above age 40 around the world. In this paper, we propose a method to detect microcalcifications in digital mammography images using two-dimensional Discrete Wavelets Transform and image enhancement techniques for removing noise as well as to get a better contrast. The initial step is applying a preprocessing techniques to improve the edge of the breast and then segmentation process (Region of interest) for eliminating some regions in the image, which are not useful for the mammography interpretation...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28240797/do-histopathological-features-and-microcalcification-affect-the-elasticity-of-breast-cancer
#8
Gamze Durhan, Pelin Seher Öztekin, Hatice Ünverdi, Tülin Değirmenci, Abdullah Durhan, Jale Karakaya, Pınar Nercis Koşar, Enver Necip Köseoğlu, Sema Hücümenoğlu
OBJECTIVES: The aim of this study was to evaluate any association between histological grade, molecular subtypes of breast cancer, and strain elastography, and to investigate whether microcalcification affects the stiffness of tumor in breast cancers with the same histological grade. METHODS: Between April 2015 and March 2016, 94 lesions of 94 patients with the diagnosis of invasive ductal carcinoma were included in the study. Strain elastography was performed on all patients before biopsy...
February 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28185408/full-field-digital-mammography-is-the-apparent-increased-detection-of-microcalcification-leading-to-over-investigation-and-over-diagnosis
#9
Alan J Porter, Elizabeth B Evans, Lisa M Erzetich
INTRODUCTION: Modern full-field digital mammography (FFDM) appears to have increased the detection of breast microcalcification. This retrospective study aimed to assess whether this is associated with over-investigation and possible over-diagnosis of breast pathology of lesser significance. METHODS: Three 2-year periods were studied, in which different mammographic technologies were used exclusively viz., classical screen-film mammography (SFM) in 2003-04, computed radiography (CR) in 2009-10 and FFDM in 2012-13...
February 9, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28182277/improving-computer-aided-detection-assistance-in-breast-cancer-screening-by-removal-of-obviously-false-positive-findings
#10
Jan-Jurre Mordang, Albert Gubern-Mérida, Alessandro Bria, Francesco Tortorella, Gerard den Heeten, Nico Karssemeijer
PURPOSE: Computer-aided detection (CADe) systems for mammography screening still mark many false positives. This can cause radiologists to lose confidence in CADe, especially when many false positives are obviously not suspicious to them. In this study, we focus on obvious false positives generated by microcalcification detection algorithms. METHODS: We aim at reducing the number of obvious false-positive findings by adding an additional step in the detection method...
February 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/28099938/bi-rads-3-5-microcalcifications-can-preoperatively-predict-breast-cancer-her2-and-luminal-a-molecular-subtype
#11
DongZhi Cen, Li Xu, Ningna Li, Zhiguang Chen, Lu Wang, Shuqin Zhou, Biao Xu, Chun Ling Liu, Zaiyi Liu, Tingting Luo
PURPOSE: To investigate associations between breast cancer molecular subtype and the patterns of mammographically detected calcifications. RESULTS: Identified were 93 (19.1%) Luminal A, 242 (49.9%) Luminal B, 108 (22.2%) HER2 and 42 (8.7%) basal subtypes. In univariate analysis, the clinicopathological parameters and BI-RADS 3-5 microcalcifications, which consisted 9 selected features was significantly associated with breast cancer molecular subtype (all P < 0...
February 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28062979/contemporary-indications-for-diagnostic-open-biopsy-in-women-assessed-for-screen-detected-breast-lesions-a-ten-year-single-institution-series-of-814-consecutive-cases
#12
Gelareh Farshid, P Grantley Gill
PURPOSE: In contemporary practice, 5% of women with non-malignant needle biopsies of screen-detected lesions still require diagnostic open biopsy (OBx). Our aims are to (i) capture a snapshot of the contemporary indications for OBx in screen-detected lesions; (ii) determine upgrade rates to malignancy (DCIS or invasive cancer); (iii) identify indications with sufficiently low upgrades to justify avoidance of OBx and (iv) propose plausible non-surgical alternatives. METHODS: Between Jan 2005 and Dec 2014, women assessed for a screen-detected lesion and recommended for OBx are included...
January 6, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28055247/staging-of-breast-cancer-and-the-advanced-applications-of-digital-mammogram-what-the-physician-needs-to-know
#13
Maha H Helal, Sahar M Mansour, Mai Zaglol, Lamia A Salaleldin, Omniya M Nada, Marwa A Haggag
OBJECTIVE: To study the role of advanced applications of digital mammogram, whether contrast-enhanced spectral mammography (CESM) or digital breast tomosynthesis (DBT), in the "T" staging of histologically proven breast cancer before planning for treatment management. METHODS: In this prospective analysis, we evaluated 98 proved malignant breast masses regarding their size, multiplicity and the presence of associated clusters of microcalcifications. Evaluation methods included digital mammography (DM), 3D tomosynthesis and CESM...
March 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28053636/increased-malignant-microcalcifications-after-neoadjuvant-chemotherapy-in-advanced-breast-cancer
#14
Gi Won Shin, Young Mi Park, Hye Kyoung Yoon, Soo Jin Jung, Tae Hyun Kim, Anbok Lee, Seok Mo Lee
In patients with advanced breast cancer, most new calcifications detected on a mammogram after neoadjuvant chemotherapy are benign dystrophic calcifications, but this is not always observed. We present a patient with advanced breast cancer who had paradoxically increased malignant microcalcifications concomitant with primary tumor regression after undergoing neoadjuvant chemotherapy. After the neoadjuvant chemotherapy, the follow-up mammogram revealed that local, fine pleomorphic microcalcifications had markedly increased...
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28053633/addition-of-digital-breast-tomosynthesis-to-full-field-digital-mammography-in-the-diagnostic-setting-additional-value-and-cancer-detectability
#15
Mirinae Seo, Jung Min Chang, Sun Ah Kim, Won Hwa Kim, Ji He Lim, Su Hyun Lee, Min Sun Bae, Hye Ryoung Koo, Nariya Cho, Woo Kyung Moon
PURPOSE: The purpose of this study was to assess the value of adding digital breast tomosynthesis (DBT) to full-field digital mammography (FFDM) in the diagnostic workup of breast cancer and to determine which lesion variables affect cancer detectability in the combined modality. METHODS: Between March and May 2012, paired FFDM and DBT images were obtained from 203 women as part of a diagnostic workup for breast cancer. Images from FFDM alone, DBT alone, and DBT combined with FFDM were reviewed in separate sessions by six blinded readers...
December 2016: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#16
S Vedantham
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#17
A O'Connell
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047520/we-fg-207a-05-dedicated-breast-ct-as-a-diagnostic-imaging-tool-physics-and-clinical-feasibility
#18
A Karellas
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047068/we-fg-207a-03-low-dose-cone-beam-breast-ct-physics-and-technology-development
#19
J Boone
Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar "densities", making lesion detection more difficult...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046435/we-de-207b-06-artifact-reduction-in-digital-breast-tomosynthesis-with-the-denoised-ordered-subset-statistically-penalized-algebraic-reconstruction-technique-dos-spart-algorithm
#20
J Garrett, Y Li, K Li, G Chen
PURPOSE: Digital breast tomosynthesis (DBT) is an emerging breast imaging modality. It uses x-ray absorption projection images acquired over a narrow angular span to provide high spatial resolution pseudo-three dimensional images for breast cancer screening and diagnosis. Unfortunately, the narrow range used to acquire data (typically <30 degrees) results in significant out of plane artifacts for high contrast objects when conventional reconstruction techniques are used. In this work, the denoised ordered-subset statistically penalized algebraic reconstruction technique (DOS-SPART) algorithm was adapted to breast tomosynthesis imaging to reduce out-of-plane blurring artifacts...
June 2016: Medical Physics
keyword
keyword
106494
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"