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https://www.readbyqxmd.com/read/28209482/effectiveness-of-a-tailored-anterior-saturation-band-in-the-improvement-of-the-image-quality-of%C3%A2-pelvic-magnetic-resonance-for-assessing-rectal%C3%A2-cancer
#1
Chen-Chang Lee, Po-Chou Chen, Hong-Hwa Chen, Chung-Cheng Huang, Li-Han Lin, Shu-Hang Ng, Min-Chi Chen, Sheung-Fat Ko
PURPOSE: We sought to test the effectiveness of the application of a tailored anterior saturation band (ASB) to improve the image quality of pelvic magnetic resonance imaging (MRI) for assessing rectal cancer. METHODS: A total of 165 patients with MRI assessment of rectal cancer between 2013 and 2015 were included. The image quality scores (4-point scale: 1, nondiagnostic through 4, excellent) of MRI without and with tailored ASBs were compared. Sensitivity, specificity, positive and negative predictive values, and accuracy of pelvic MRIs with and without a tailored ASB for T-staging in 65 patients with direct surgery and 67 patients with chemoradiotherapy before surgery were evaluated...
January 25, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28206859/evaluation-and-adaptation-of-attractive-toxic-sugar-baits-for-culex-tarsalis-and-culex-quinquefasciatus-control-in-the-coachella-valley-southern-california
#2
Whitney A Qualls, Jodi Scott-Fiorenzano, Gunter C Müller, Kristopher L Arheart, John C Beier, Rui-De Xue
The project goal was to determine how a new vector control strategy that targets the sugar-feeding behavior of mosquitoes, attractive toxic sugar baits (ATSBs), can be used to more effectively control West Nile virus (WNV) vectors in the Coachella Valley, California. Three laboratory studies were conducted to determine the utility of this method for control against Culex quinquefasciatus and Culex tarsalis : 1) efficacy evaluations of 2 formulations of ATSB, microencapsulated garlic oil, and a combination of microencapsulated garlic oil and 1% boric acid; 2) choice assays to determine the attractiveness of ATSB with the microencapsulated garlic oil against attractive sugar baits (ASB; the attractant alone; without toxin) and a 10% sucrose solution; and 3) vegetation efficacy tests on 3 common plant species in the Coachella Valley, Atriplex lentiformis, Tamarix ramosissima , and Pluchea sericea...
December 2016: Journal of the American Mosquito Control Association
https://www.readbyqxmd.com/read/28131446/human-exposure-assessment-of-different-arsenic-species-in-household-water-sources-in-a-high-risk-arsenic-area
#3
Hifza Rasheed, Paul Kay, Rebecca Slack, Yun Yun Gong, Annie Carter
Understanding arsenic speciation in water is important for managing the potential health risks associated with chronic arsenic exposure. Most arsenic monitoring studies to date have only measured total arsenic, with few looking at arsenic species. This study assessed 228 ground water sources in six unstudied villages in Pakistan for total, inorganic and organic arsenic species using ion chromatography inductively coupled plasma collision reaction cell mass spectrometry. The concentration levels approached 3090μgL(-1) (95% CI, 130...
January 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28112866/sweetened-beverage-intake-in-association-to-energy-and-sugar-consumption-and-cardiometabolic-markers-in-children
#4
P Seferidi, C Millett, A A Laverty
BACKGROUND: Artificially sweetened beverages (ASBs) are promoted as healthy alternatives to sugar-sweetened beverages (SSBs) in order to reduce sugar intake, but their effects on weight control and glycaemia have been debated. This study examines associations of SSBs and ASBs with energy and sugar intake and cardiometabolic measures. METHODS: One thousand six hundred eighty-seven children aged 4-18 participated in the National Diet and Nutrition Survey Rolling Programme (2008/9-2011/12) in the UK...
January 23, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28088454/alpha-l-iduronidase-and-arylsulfatase-b-in-dried-blood-spots-on-filter-paper-biochemical-parameters-and-time-stability
#5
Ana Carolina Breier, Jaqueline Cé, Jamila Mezzalira, Vanessa V Daitx, Vitoria C Moraes, Mariana P S Goldim, Janice C Coelho
BACKGROUND: The goal of this study was to assess the biochemical parameters of the enzymes α-l-iduronidase (IDUA) and arylsulfatase B (ASB), which are deficient in mucopolysaccharidosis (MPS) I and VI, respectively, in dried blood spot (DBS) samples impregnated on filter paper. METHODS AND RESULTS: The optimal pH, Km, and Vmax of IDUA and ASB in DBS are hereby presented. After these analyses, the reference values for the activities of these enzymes in DBS with cutoff of 3...
January 11, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28088228/the-loss-of-function-mutations-and-down-regulated-expression-of-asb3-gene-promote-the-growth-and-metastasis-of-colorectal-cancer-cells
#6
Wu-Ying Du, Zhen-Hai Lu, Wen Ye, Xiang Fu, Yi Zhou, Chun-Mei Kuang, Jiang-Xue Wu, Zhi-Zhong Pan, Shuai Chen, Ran-Yi Liu, Wen-Lin Huang
BACKGROUND: Ankyrin repeat and SOCS box protein 3 (ASB3) is a member of ASB family and contains ankyrin repeat sequence and SOCS box domain. Previous studies indicated that it mediates the ubiquitination and degradation of tumor necrosis factor receptor 2 and is likely involved in inflammatory responses. However, its effects on oncogenesis are unclear. This study aimed to investigate the effects of ASB3 on the growth and metastasis of colorectal cancer (CRC). METHODS: We used next-generation sequencing or Sanger sequencing to detect ASB3 mutations in CRC specimens or cell lines, and used real-time quantitative polymerase chain reaction, Western blotting, and immunohistochemical or immunofluorescence assay to determine gene expression...
January 14, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28074617/soft-drink-intake-and-the-risk-of-metabolic-syndrome-a%C3%A2-systematic-review-and-meta-analysis
#7
REVIEW
Aditya Narain, Chun Shing Kwok, Mamas A Mamas
BACKGROUND: It is unclear whether consumption of sugar- or artificially sweetened beverages is independently associated with the development of metabolic syndrome. A systematic review and meta-analysis was performed to evaluate whether soft drink consumption is associated with the development of metabolic syndrome. METHODS: Medline and EMBASE were searched in November 2015 for studies which considered soft drink (sugar-sweetened beverage [SSB] and artificially sweetened beverage [ASB]) intake and risk of metabolic syndrome...
January 10, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28069991/community-alcohol-partnerships-with-the-alcohol-industry-what-is-their-purpose-and-are-they-effective-in-reducing-alcohol-harms
#8
M Petticrew, N Douglas, P D'Souza, Y M Shi, M A Durand, C Knai, E Eastmure, N Mays
BACKGROUND: Local initiatives to reduce alcohol harms are common. One UK approach, Community Alcohol Partnerships (CAPs), involves partnerships between the alcohol industry and local government, focussing on alcohol misuse and anti-social behaviour (ASB) among young people. This study aimed to assess the evidence of effectiveness of CAPs. METHODS: We searched CAP websites and documents, and databases, and contacted CAPs to identify evaluations and summarize their findings...
January 9, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28057066/evaluations-of-dual-attractant-toxic-sugar-baits-for-surveillance-and-control-of-aedes-aegypti-and-aedes-albopictus-in-florida
#9
Jodi M Scott-Fiorenzano, Alice P Fulcher, Kelly E Seeger, Sandra A Allan, Daniel L Kline, Philip G Koehler, Günter C Müller, Rui-De Xue
BACKGROUND: Dual attractant toxic sugar baits (D-ATSB) containing two host kairomones, L-lactic (LA) and 1-octen-3-ol (O), and fruit-based attractants were evaluated through olfactory, consumption and mortality, and semi-field experiments to determine if host kairomones could first, enhance attraction of a fruit-based (attractant) toxic sugar bait (ATSB), and second, increase the efficacy of a fruit based attractive toxic sugar bait (ATSB). METHODS: Four combinations of LA and O were incorporated into the ATSB and evaluated in an olfactometer to determine if these combinations could enhance attraction of Aedes aegypti (L...
January 5, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28054716/arsenic-resistance-genes-of-as-resistant-purple-nonsulfur-bacteria-isolated-from-as-contaminated-sites-for-bioremediation-application
#10
Phitthaya Nookongbut, Duangporn Kantachote, Kannan Krishnan, Mallavarapu Megharaj
This study aimed to identify arsenic resistant mechanisms in As-resistant purple nonsulfur bacteria (PNSB) by screening them for presence of As-resistance genes and related enzymes. Resistance to As(III) and As(V) of four As-resistant PNSB determined in terms of median inhibition concentration (IC50 values) were in the order of strains Rhodopseudomonas palustris C1 > R. palustris AB3 > Rubrivivax benzoatilyticus C31 > R. palustris L28 which corresponded to the presence of As-resistance genes in these bacteria...
January 5, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28035110/bioassay-evaluation-of-residual-activity-of-attractive-toxic-sugar-treated-barrier-fence-in-the-control-of-phlebotomus-papatasi-diptera-psychodidae
#11
Abedin Saghafipour, Hassan Vatandoost, Ali Reza Zahraei-Ramazani, Mohammad Reza Yaghoobi-Ershadi, Yavar Rassi, Mohammad Reza Shirzadi, Amir Ahmad Akhavan
BACKGROUND & OBJECTIVES: Phlebotomus papatasi is the main vector of the zoonotic cutaneous leishmaniasis (ZCL) in Qom Province and many other provinces of Iran. Attractive toxic sugar baits (ATSB) treated barrier fence is one of the new methods for controlling the vectors such as sandflies. The present study was designed to evaluate the residual activity of ATSB-treated barrier fence that was used in control of P. papatasi. METHODS: Following the selection of villages in Markazi district of Qom Province, central Iran during 2015 for ATSB and ASB (bait containing no active ingredient) methods; barrier fences on the ground in front of the rodent's colony were installed...
October 2016: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28008717/pharmacokinetics-tissue-distribution-and-excretion-studies-of-l-isocorypalmine-using-ultra-high-performance-liquid-chromatography-with-tandem-mass-spectrometry
#12
Weihui Wang, Jing Liu, Xiaoning Zhao, Yan Peng, Nannan Wang, David Y W Lee, Ronghua Dai
l-Isocorypalmine is a newly identified metabolite of l-tetrahydropalmatine with a unique dual pharmacological profile as a partial dopamine receptor 1 agonist and dopamine receptor 2 antagonist properties for treating cocaine use disorder. The purpose of this study was to explore the pharmacokinetic profiles, tissue distribution and excretion of l-isocorypalmine in Sprague-Dawley rats. A sensitive and reliable ultra high performance liquid chromatography with tandem mass spectrometry method was developed and validated for determination of l-isocorypalmine in biological samples...
December 23, 2016: Journal of Separation Science
https://www.readbyqxmd.com/read/28007181/methylated-and-thiolated-arsenic-species-for-environmental-and-health-research-a-review-on-synthesis-and-characterization
#13
REVIEW
William R Cullen, Qingqing Liu, Xiufen Lu, Anthony McKnight-Whitford, Hanyong Peng, Aleksandra Popowich, Xiaowen Yan, Qi Zhang, Michael Fricke, Hongsui Sun, X Chris Le
Hundreds of millions of people around the world are exposed to elevated concentrations of inorganic and organic arsenic compounds, increasing the risk of a wide range of health effects. Studies of the environmental fate and human health effects of arsenic require authentic arsenic compounds. We summarize here the synthesis and characterization of more than a dozen methylated and thiolated arsenic compounds that are not commercially available. We discuss the methods of synthesis for the following 14 trivalent (III) and pentavalent (V) arsenic compounds: monomethylarsonous acid (MMA(III)), dicysteinylmethyldithioarsenite (MMA(III)(Cys)2), monomethylarsonic acid (MMA(V)), monomethylmonothioarsonic acid (MMMTA(V)) or monothio-MMA(V), monomethyldithioarsonic acid (MMDTA(V)) or dithio-MMA(V), monomethyltrithioarsonate (MMTTA(V)) or trithio-MMA(V), dimethylarsinous acid (DMA(III)), dimethylarsino-glutathione (DMA(III)(SG)), dimethylarsinic acid (DMA(V)), dimethylmonothioarsinic acid (DMMTA(V)) or monothio-DMA(V), dimethyldithioarsinic acid (DMDTA(V)) or dithio-DMA(V), trimethylarsine oxide (TMAO(V)), arsenobetaine (AsB), and an arsenicin-A model compound...
November 2016: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28000782/local-scale-projections-of-coral-reef-futures-and-implications-of-the-paris-agreement
#14
Ruben van Hooidonk, Jeffrey Maynard, Jerker Tamelander, Jamison Gove, Gabby Ahmadia, Laurie Raymundo, Gareth Williams, Scott F Heron, Serge Planes
Increasingly frequent severe coral bleaching is among the greatest threats to coral reefs posed by climate change. Global climate models (GCMs) project great spatial variation in the timing of annual severe bleaching (ASB) conditions; a point at which reefs are certain to change and recovery will be limited. However, previous model-resolution projections (~1 × 1°) are too coarse to inform conservation planning. To meet the need for higher-resolution projections, we generated statistically downscaled projections (4-km resolution) for all coral reefs; these projections reveal high local-scale variation in ASB...
December 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27956252/clinical-features-management-considerations-and-outcomes-in-a-case-series-of-patients-with-parasellar-intracranial-aneurysms-undergoing-anterior-skull-base-surgery
#15
Daniel M Raper, Dale Ding, Elizabeth Evans, Robert M Starke, R Webster Crowley, Kenneth C Liu, Edward H Oldfield, John A Jane
BACKGROUND: The co-incidence of parasellar aneurysms (IA) and anterior skull base (ASB) lesions, while rare, presents a management challenge. IAs embedded within, or adjacent to, ASB lesions are at risk in the perioperative period, and may have unique presentations, natural histories, and outcomes. The objective of this study was to outline management options and nuances in patients with coexisting IAs and ASB lesions. METHODS: We retrospectively evaluated all patients who presented for management of IAs and ASB lesions from January 2006 to January 2014...
December 9, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27932313/3rd-congress-on-applied-synthetic-biology-in-europe-costa-da-caparica-portugal-february-2016
#16
Miguel Cueva
The third meeting organised by the European Federation of Biotechnology (EFB) on advances in Applied Synthetic Biotechnology in Europe (ASBE) was held in Costa da Caparica, Portugal, in February 2016. Abundant novel applications in synthetic biology were described in the six sessions of the meeting, which was divided into technology and tools for synthetic biology (I, II and III), bionanoscience, biosynthetic pathways and enzyme synthetic biology, and metabolic engineering and chemical manufacturing. The meeting presented numerous methods for the development of novel synthetic strains, synthetic biological tools and synthetic biology applications...
March 25, 2017: New Biotechnology
https://www.readbyqxmd.com/read/27880879/arsenic-levels-among-pregnant-women-and-newborns-in-canada-results-from-the-maternal-infant-research-on-environmental-chemicals-mirec-cohort
#17
Adrienne S Ettinger, Tye E Arbuckle, Mandy Fisher, Chun Lei Liang, Karelyn Davis, Ciprian-Mihai Cirtiu, Patrick Bélanger, Alain LeBlanc, William D Fraser
Arsenic is a common environmental contaminant from both naturally-occurring and anthropomorphic sources and human exposure can be detected in various tissues. Its toxicity depends on many factors including the chemical form, valence state, bioavailability, metabolism and detoxification within the human body. Of paramount concern, particularly with respect to health effects in children, is the timing of exposure as the prenatal and early life periods are more susceptible to toxic effects. The Maternal-Infant Research on Environmental Chemicals (MIREC) cohort was established to obtain national-level biomonitoring data for approximately 2,000 pregnant women and their infants between 2008 and 2011 from 10 Canadian cities...
November 20, 2016: Environmental Research
https://www.readbyqxmd.com/read/27868218/simultaneous-determination-of-l-tetrahydropalmatine-and-its-active-metabolites-in-rat-plasma-by-a-sensitive-ultra-high-performance-liquid-chromatography-with-tandem-mass-spectrometry-method-and-its-application-in-a-pharmacokinetic-study
#18
Weihui Wang, Jing Liu, Xiaoning Zhao, Yan Peng, Nannan Wang, David Y W Lee, Ronghua Dai
A sensitive and reliable ultra high performance liquid chromatography with tandem mass spectrometry (UHPLC-MS/MS) method was developed and validated for simultaneous determination of L-tetrahydropalmatine (L-THP) and its active metabolites L-isocorypalmine (L-ICP) and L-corydalmine (L-CD) in rat plasma,. The analytes were extracted by liquid-liquid extraction and separated on a Bonshell ASB C18 column (2.1 mm × 100 mm; 2.7 µm; Agela) using acetonitrile-formic acid aqueous as mobile phase at a flow rate of 0...
November 21, 2016: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/27866338/reflections-on-serving-remote-mountain-communities-mobile-hospitals-and-women-s-and-children-s-health-care-in-northern-haiti
#19
Rose-Marie Chierici, Thony Michelet Voltaire
In 2003 Alyans Sante Borgne's (ASB) conducted the first week-long mobile hospital in Molas, a poor mountain community a 10-h walk from the main hospital in the town of Borgne in North Haiti. ASB is a partnership between Haiti Outreach-Pwoje Espwa (H.O.P.E.), a US-based NGO, and Haiti's Ministry of Health. The paper reflects on this first experience and the evolution of an indigenous model of health care delivery, Sante Nan Lakou (SNL)/Health at the Extended Family Level, a model that prioritizes the needs of patients over those of the institution...
November 19, 2016: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/27849023/the-genesis-of-adiabatic-shear-bands
#20
P Landau, S Osovski, A Venkert, V Gärtnerová, D Rittel
Adiabatic shear banding (ASB) is a unique dynamic failure mechanism that results in an unpredicted catastrophic failure due to a concentrated shear deformation mode. It is universally considered as a material or structural instability and as such, ASB is hardly controllable or predictable to some extent. ASB is modeled on the premise of stability analyses. The leading paradigm is that a competition between strain (rate) hardening and thermal softening determines the onset of the failure. It was recently shown that microstructural softening transformations, such as dynamic recrystallization, are responsible for adiabatic shear failure...
November 16, 2016: Scientific Reports
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