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nanopartical Au

Yan-Qing Yu, Ji-Peng Wang, Min Zhao, Lin-Ru Hong, Ya-Qin Chai, Ruo Yuan, Ying Zhuo
Herein, a new electrochemiluminescence (ECL) strategy for enzyme-free microRNA-21 (miR-21) amplified detection was designed based on target-catalyzed hairpin assembly by combining the signal-amplification capability of both intramolecular and intermolecular ECL co-reaction. In this strategy, two hairpin DNA probes of H1 and H2 were designed as capture probes and detection probes, respectively. To be specific, the capture probes of H1 were immobilized on the multilayer interface of AuNPs and thiosemicarbazide (TSC) assembly on the single-walled carbon nanohorns decorated electrode, while the detection probes of H2 was anchored on the nanocarriers of gold nanoparticals functionalized reduced graphene oxide (Au-rGO) which were tagged with the self-enhanced ruthenium complex (PEI-Ru(ΙΙ)) in advance...
March 15, 2016: Biosensors & Bioelectronics
Kun Guo, Rui Xiao, Xiaoye Zhang, Chaoguang Wang, Qiqi Liu, Zhen Rong, Lin Ye, Suhong Chen
Surface-enhanced Raman detection of thiram is demonstrated by using Ag-nanoparticles (Ag NPs) on Au film over nanosphere (AuFON) substrate as the hybrid substrate. The SERS signal of the Ag NPs attached to solid supports is studied. The close coupling together of thousands of Ag NPs on AuFON leads to the generation of hot spots for SERS. The Ag NPs on AuFON can be applied to detect rhodamine-6G (R6G) with the detection limitation of 10-11 M and the pesticide thiram in acetone with a detection limit of as low as 0...
April 9, 2015: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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