Lu Yin, Zhengyang Xu, Ling Wang, Wei Li, Yue Zhao, Yongbin Su, Wei Sun, Yandong Liu, Minghui Yang, Aihong Yu, Glen Mervyn Blake, Xinbao Wu, Annegreet G Veldhuis-Vlug, Xiaoguang Cheng, Karen Hind, Klaus Engelke
Background and Purpose: Muscle weakness and bone fragility are both associated with hip fracture. In general, muscle contractions create forces to the bone, and bone strength adapts to mechanical loading through changes in bone architecture and mass. However, the relationship between impairment of muscle and bone function remain unclear. In particular, the associations of muscle with properties of proximal femur cortical and trabecular bone are still not well understood. The aim of this study was to explore the associations of hip/thigh muscle density (CT attenuation value in Hounsfield units) and size with cortical and trabecular bone mineral density (BMD) of the proximal femur...
2020: Frontiers in Endocrinology