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Alessandro Minguzzi, Alberto Naldoni, Ottavio Lugaresi, Elisabetta Achilli, Francesco D'Acapito, Francesco Malara, Cristina Locatelli, Alberto Vertova, Sandra Rondinini, Paolo Ghigna
Electrochemical devices for energy conversion and storage are central for a sustainable economy. The performance of electrodes is driven by charge transfer across different layer materials and an understanding of the mechanistics is pivotal to gain improved efficiency. Here, we directly observe the transfer of photogenerated charge carriers in a photoanode made of hematite (α-Fe2O3) and a hydrous iridium oxide (IrOx) overlayer, which plays a key role in photoelectrochemical water oxidation. Through the use of operando X-ray absorption spectroscopy (XAS), we probe the change in occupancy of the Ir 5d levels during optical band gap excitation of α-Fe2O3...
February 22, 2017: Physical Chemistry Chemical Physics: PCCP
Diego Giannandrea, Julián Achilli Lucas, Lucía Saldaño, María J Barrenengoa, Mariano Dramis, Mariano Barraco, Matías González Olivi, María T Burry
OBJECTIVE: To define the profile and the treatments evolution of the outpatients assisted by the psychiatry residents of the Rossi Hospital in La Plata. METHODS: It was analyzed the period between 2005 and 2010 (six years). The variables selected included gender, age, diagnosis (according to ICD 10), duration and evolution of treatment. RESULTS: From the total number of patients (n=341), 58,7% were women (n= 200) and 41,3% men (n= 141). The most frequent diagnoses were: anxiety disorders (13,6%), depressive disorders (12,8%), schizophrenia (12,2%), other non-affective psychoses (9%) and mental retardation (8,4%)...
March 2016: Vertex: Revista Argentina de Psiquiatriá
Anna Olivieri, Carlo Sidore, Alessandro Achilli, Andrea Angius, Cosimo Posth, Anja Furtwängler, Stefania Brandini, Marco Rosario Capodiferro, Francesca Gandini, Magdalena Zoledziewska, Maristella Pitzalis, Andrea Maschio, Fabio Busonero, Luca Lai, Robin Skeates, Maria Giuseppina Gradoli, Jessica Beckett, Michele Marongiu, Vittorio Mazzarello, Patrizia Marongiu, Salvatore Rubino, Teresa Rito, Vincent Macaulay, Ornella Semino, Maria Pala, Gonçalo R Abecasis, David Schlessinger, Eduardo Conde-Sousa, Pedro Soares, Martin B Richards, Francesco Cucca, Antonio Torroni
No abstract text is available yet for this article.
February 8, 2017: Molecular Biology and Evolution
Giuseppe Paciocco, Andrea Lombi, Antonella Vincenzi, Alberto Pesci, Felice Achilli
We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy, including i.v. epoprostenol, was started. The rapid institution of this treatment regimen allowed a complete right ventricular reverse remodelling after 1 year of therapy, leading to a down-titration until complete suspension of epoprostenol from the treatment regimen...
2017: Respiratory Medicine Case Reports
S Tognolini, S Achilli, L Longetti, E Fava, C Mariani, M I Trioni, S Pagliara
No abstract text is available yet for this article.
December 2, 2016: Physical Review Letters
Aslı Şahin, Aaron Held, Kirsten Bredvik, Paxton Major, Toni-Marie Achilli, Abigail G Kerson, Kristi Wharton, Geoff Stilwell, Robert Reenan
Amyotrophic Lateral Sclerosis (ALS) is the most common adult-onset motor neuron disease and familial forms can be caused by numerous dominant mutations of the copper-zinc superoxide dismutase 1 (SOD1) gene. Substantial efforts have been invested in studying SOD1-ALS transgenic animal models; yet, the molecular mechanisms by which ALS-mutant SOD1 protein acquires toxicity are not well understood. ALS-like phenotypes in animal models are highly dependent on transgene dosage. Thus, issues of whether the ALS-like phenotypes of these models stem from overexpression of mutant alleles or from aspects of the SOD1 mutation itself are not easily deconvolved...
February 2017: Genetics
Vincenza Battaglia, Paolo Gabrieli, Stefania Brandini, Marco R Capodiferro, Pio A Javier, Xiao-Guang Chen, Alessandro Achilli, Ornella Semino, Ludvik M Gomulski, Anna R Malacrida, Giuliano Gasperi, Antonio Torroni, Anna Olivieri
In the last 40 years, the Asian tiger mosquito Aedes albopictus, indigenous to East Asia, has colonized every continent except Antarctica. Its spread is a major public health concern, given that this species is a competent vector for numerous arboviruses, including those causing dengue, chikungunya, West Nile, and the recently emerged Zika fever. To acquire more information on the ancestral source(s) of adventive populations and the overall diffusion process from its native range, we analyzed the mitogenome variation of 27 individuals from representative populations of Asia, the Americas, and Europe...
2016: Frontiers in Genetics
Chiara Achilli, Jyotsna Pundir, Parimalam Ramanathan, Luca Sabatini, Haitham Hamoda, Nick Panay
OBJECTIVE: To systematically review and summarize the existing evidence related to the efficacy and safety of transdermal T in postmenopausal women for the treatment of hypoactive sexual desire disorder (HSDD). DESIGN: Systematic reviews and meta-analysis. SETTING: Not applicable. PATIENT(S): Seven randomized controlled trials enrolled 3,035 participants; 1,350 women were randomized to treatment with T patch, and 1,379 women were randomized to placebo...
February 2017: Fertility and Sterility
I Gualandi, M Marzocchi, A Achilli, D Cavedale, A Bonfiglio, B Fraboni
The development of wearable chemical sensors is receiving a great deal of attention in view of non-invasive and continuous monitoring of physiological parameters in healthcare applications. This paper describes the development of a fully textile, wearable chemical sensor based on an organic electrochemical transistor (OECT) entirely made of conductive polymer (PEDOT:PSS). The active polymer patterns are deposited into the fabric by screen printing processes, thus allowing the device to actually "disappear" into it...
September 26, 2016: Scientific Reports
C Achilli, S Grandi, G F Guidetti, A Ciana, C Tomasi, D Capsoni, G Minetti
Magnetite nanoparticles coated with silica, obtained by a sol-gel process in the reverse micelle microemulsion, were characterized and homogeneously suspended in water in order to assay their biocompatibility toward blood cells, in view of a potential medical use of this material. Their hemolytic, pro-thrombotic and pro-inflammatory properties were observed.
October 20, 2016: Biomaterials Science
Tomasz Baran, Szymon Wojtyła, Cristina Lenardi, Alberto Vertova, Paolo Ghigna, Elisabetta Achilli, Martina Fracchia, Sandra Rondinini, Alessandro Minguzzi
Light-driven water splitting is one of the most promising approaches for using solar energy in light of more sustainable development. In this paper, a highly efficient p-type copper(II) oxide photocathode is studied. The material, prepared by thermal treatment of CuI nanoparticles, is initially partially reduced upon working conditions and soon reaches a stable form. Upon visible-light illumination, the material yields a photocurrent of 1.3 mA cm(-2) at a potential of 0.2 V vs a reversible hydrogen electrode at mild pH under illumination by AM 1...
August 24, 2016: ACS Applied Materials & Interfaces
Francesca Gandini, Alessandro Achilli, Maria Pala, Martin Bodner, Stefania Brandini, Gabriela Huber, Balazs Egyed, Luca Ferretti, Alberto Gómez-Carballa, Antonio Salas, Rosaria Scozzari, Fulvio Cruciani, Alfredo Coppa, Walther Parson, Ornella Semino, Pedro Soares, Antonio Torroni, Martin B Richards, Anna Olivieri
Rare mitochondrial lineages with relict distributions can sometimes be disproportionately informative about deep events in human prehistory. We have studied one such lineage, haplogroup R0a, which uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, from Europe to India. We conclude that: (1) the lineage ancestral to R0a is more ancient than previously thought, with a relict distribution across the Mediterranean/Southwest Asia; (2) R0a has a much deeper presence in Arabia than previously thought, highlighting the role of at least one Pleistocene glacial refugium, perhaps on the Red Sea plains; (3) the main episode of dispersal into Eastern Africa, at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions from one or more refugia in Arabia; (4) there was likely a minor Late Glacial/early postglacial dispersal from Arabia through the Levant and into Europe, possibly alongside other lineages from a Levantine refugium; and (5) the presence of R0a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ~3 ka between Africa and the Indian Ocean led to some gene flow even further afield, into Iran, Pakistan and India...
2016: Scientific Reports
Irene Cardinali, Hovirag Lancioni, Andrea Giontella, Marco Rosario Capodiferro, Stefano Capomaccio, Luca Buttazzoni, Giovanni Paolo Biggio, Raffaele Cherchi, Emidio Albertini, Anna Olivieri, Katia Cappelli, Alessandro Achilli, Maurizio Silvestrelli
BACKGROUND: The climatic and cultural diversity of the Italian Peninsula triggered, over time, the development of a great variety of horse breeds, whose origin and history are still unclear. To clarify this issue, analyses on phenotypic traits and genealogical data were recently coupled with molecular screening. METHODOLOGY: To provide a comprehensive overview of the horse genetic variability in Italy, we produced and phylogenetically analyzed 407 mitochondrial DNA (mtDNA) control-region sequences from ten of the most important Italian riding horse and pony breeds: Bardigiano, Esperia, Giara, Lipizzan, Maremmano, Monterufolino, Murgese, Sarcidano, Sardinian Anglo-Arab, and Tolfetano...
2016: PloS One
Erica Rurali, Beatrice Bassetti, Gianluca Lorenzo Perrucci, Marco Zanobini, Cristina Malafronte, Felice Achilli, Elisa Gambini
The bone marrow (BM) is a well-recognized source of stem/progenitor cells for cell therapy in cardiovascular diseases (CVDs). Preclinical and clinical studies suggest that endothelial progenitor cells (EPCs) contribute to reparative process of vascular endothelium and participate in angiogenesis. As for all organs and cells across the lifespan, BM and EPCs are negatively impacted by ageing due to microenvironment modifications and EPC progressive dysfunctions. The encouraging results in terms of neovascularization observed in young animals after EPC administration were mitigated in aged patients treated for ischemic CVDs...
October 2016: Mechanisms of Ageing and Development
Ye Li, Xi-sheng Weng, Jin Lin, Jin Jin, Wen-wei Qian, Bao-zhong Zhang, Peng Gao, Ji-liang Zhai
OBJECTIVE: To investigate the effectiveness of our department's therapeutic regimen and treatment of complications during the perioperative period of hemophilia-related osteoarthropathy. METHODS: In this retrospective study, data on 101 patients with hemophilia who had undergone operative treatment in our hospital from January 2000 to August 2014 were assessed. Ninety-one of the patients had hemophilia A and 10 hemophilia B. All patients were male. Changes in Hospital for Special Surgery (HSS), Harris and American Orthopedic Foot and Ankle Society (AOFAS) scores, occurrence of complications during the perioperative period and the clinical treatment and prognosis pre- and postoperatively and during follow-up were analyzed...
February 2016: Orthopaedic Surgery
L Döderlein, C Dussa
BACKGROUND: The apophysis of the calcaneal bone forms an insertional region for the strong plantarflexors with the Achillis tendon and serves as an origin for the plantar aponeurosis and the short intrinsic foot muscles. Both components create a tendinous sling whithin which the apophysis acts as a pivot, which functions when it runs a straight course and its tension is adequate. This mechanism results in combined tractional and compressional forces which work together with the ground reaction forces during gait as molding elements of the calcaneous bone...
March 2016: Der Orthopäde
Stefano Maggiolini, Gaetano Gentile, Andrea Farina, Caterina C De Carlini, Laura Lenatti, Ester Meles, Felice Achilli, Angela Tempesta, Antonio Brucato, Massimo Imazio
Pericardiocentesis is useful in the diagnosis and treatment of pericardial effusive disease. To date, a number of methods have been developed to reduce complications and increase the success rate of the procedure. The aim of the present study was to evaluate the efficacy and the safety of echocardiography-guided pericardiocentesis under continuous echocardiographic monitoring in the management of pericardial effusion. We prospectively performed 161 pericardiocentesis procedures in 141 patients admitted from 1993 to 2015 in 3 centers...
April 15, 2016: American Journal of Cardiology
Elisabetta Achilli, Alessandro Minguzzi, Alberto Visibile, Cristina Locatelli, Alberto Vertova, Alberto Naldoni, Sandra Rondinini, Ferdinando Auricchio, Stefania Marconi, Martina Fracchia, Paolo Ghigna
Three-dimensional printed multi-purpose electrochemical devices for X-ray absorption spectroscopy are presented in this paper. The aim of this work is to show how three-dimensional printing can be a strategy for the creation of electrochemical cells for in situ and in operando experiments by means of synchrotron radiation. As a case study, the description of two cells which have been employed in experiments on photoanodes for photoelectrochemical water splitting are presented. The main advantages of these electrochemical devices are associated with their compactness and with the precision of the three-dimensional printing systems which allows details to be obtained that would otherwise be difficult...
March 2016: Journal of Synchrotron Radiation
Hovirag Lancioni, Piera Di Lorenzo, Irene Cardinali, Simone Ceccobelli, Marco Rosario Capodiferro, Alessandro Fichera, Viola Grugni, Ornella Semino, Luca Ferretti, Anthony Gruppetta, George Attard, Alessandro Achilli, Emiliano Lasagna
No abstract text is available yet for this article.
April 2016: Animal Genetics
Thomas Bathon, Simona Achilli, Paolo Sessi, Vladimir Andreevich Golyashov, Konstantin Aleksandrovich Kokh, Oleg Evgenievich Tereshchenko, Matthias Bode
A Bi2Te3 single crystal is grown with the modified Bridgman technique. The crystal has a nominal composition with a Te content of 61 mol% resulting in the existence of two distinct regions, p- and n-doped, respectively; color-coded tunneling spectra are taken over 60 nm at the transition region.
March 16, 2016: Advanced Materials
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