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Prescription Drug Monitoring Database

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https://www.readbyqxmd.com/read/29731947/patterns-of-antibiotic-prescription-in-children-tirana-albania-region
#1
Joana Mihani, Suela Këlliçi
BACKGROUND: Antibiotics (abx) constitute the most prescribed therapeutic agent in the world. There is little data regarding antibiotic consumption by young children in Albania. AIM: This study aims to evaluate antibiotic prescription in children in quantitative and qualitative terms, and therefore, propose recommendations to improve overall clinical outcomes. METHODS: A retrospective, cross-sectional drug utilisation study was conducted based on unreimbursed prescriptions collected in 25 pharmacies, randomly selected within the district of Tirana, during the period beginning December 2015 to January 2016...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29725863/persistence-of-and-switches-from-teriparatide-treatment-among-women-and-men-with-osteoporosis-in-the-real-world-a-claims-database-analysis
#2
Tomoko Usui, Masaru Funagoshi, Kahori Seto, Kazuki Ide, Shiro Tanaka, Koji Kawakami
This study investigated the real-world persistence rate and switches of teriparatide-treated patients using a claims database in Japan. The persistence rate of teriparatide at 12 months was 34.9%, and approximately one-third of the patients were not treated with any osteoporosis drugs after teriparatide. Improvement in persistence and switches are desired. PURPOSE: We aimed to elucidate the persistence rates and switches before and after teriparatide treatment in real-world osteoporosis patients based on data from a medical claims database in Japan...
May 3, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29656805/multiple-opioid-prescriptions-among-privately-insured-dental-patients-in-the-united-states-evidence-from-claims-data
#3
Niodita Gupta, Marko Vujicic, Andrew Blatz
BACKGROUND: Multiple or high dosage opioid prescriptions increase the risk of experiencing drug misuse and overdose. The authors examine index (first) and follow-up opioid prescriptions for 1 year among privately insured dental patients in the United States from 2010 through 2015. METHODS: The authors used the 2010 through 2015 Truven Health MarketScan Research databases and the Prescription Drug Monitoring Program Training Technical Assistance Center conversion data set...
April 12, 2018: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29624189/improving-the-safety-of-opioid-use-for-acute-noncancer-pain-in-hospitalized-adults-a-consensus-statement-from-the-society-of-hospital-medicine
#4
Shoshana J Herzig, Hilary J Mosher, Susan L Calcaterra, Anupam B Jena, Teryl K Nuckols
Hospital-based clinicians frequently treat acute, noncancer pain. Although opioids may be beneficial in this setting, the benefits must be balanced with the risks of adverse events, including inadvertent overdose and prolonged opioid use, physical dependence, or development of opioid use disorder. In an era of epidemic opioid use and related harms, the Society of Hospital Medicine (SHM) convened a working group to develop a consensus statement on opioid use for adults hospitalized with acute, noncancer pain, outside of the palliative, end-of-life, and intensive care settings...
April 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29600603/-current-research-situation-of-nephrotoxicity-of-chinese-herbal-medicine
#5
Xue Feng, Sai-Nan Fang, Yu-Xin Gao, Jian-Ping Liu, Wei Chen
To provide the basis for the future research on the nephrotoxicity of Chinese herbal medicine through systematic and comprehensive summary of all the Chinese herbal medicines which may lead to nephrotoxicity. Foreign resources included PubMed and Cochrane library, and domestic research resources was China Food and Drug Administration(CDFA) Adverse Drug Reaction Monitoring Center database. The databases were searched from establishment to January 1, 2017. There was no limitation on research type. 28 English studies were found, including 97 Chinese herbs or prescriptions with the risk of nephrotoxicity...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29599017/opioid-prescribing-practices-from-2010-through-2015-among-dentists-in-the-united-states-what-do-claims-data-tell-us
#6
Niodita Gupta, Marko Vujicic, Andrew Blatz
BACKGROUND: Dentists wrote 6.4% of all opioid prescriptions in the United States in 2012. The purpose of this study was to examine opioid prescription rates, dosage of opioids prescribed, type of opioid drug prescribed, and type of dental visit at which dentists prescribe opioids. METHODS: The authors used the 2010 through 2015 Truven Health Marketscan Research databases and the Prescription Drug Monitoring Program (PDMP) Training and Technical Assistance Center conversion data set...
April 2018: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29573622/ageing-opioid-users-increased-risk-of-methadone-specific-death-in-the-uk
#7
Matthias Pierce, Tim Millar, J Roy Robertson, Sheila M Bird
BACKGROUND: The first evidence that the hazard ratio (HR) for methadone-specific death rises more steeply with age-group than for all drug-related deaths (DRDs) came from Scotland's cohort of 33,000 methadone-prescription clients. We aim to examine, for England, whether illicit opioid users' risk of methadone-specific death increases with age; and to pool age-related HRs for methadone-specific deaths with those for Scotland's methadone-prescription clients. METHODS: The setting is all services in England that provide publicly-funded, structured treatment for illicit opioid users, the methodology linkage of the English National Drug Treatment Monitoring System and mortality database, and key measurements are DRDs, methadone-specific DRDs, or heroin-specific DRDs, by age-group and gender, with proportional hazards adjustment for substances used, injecting status and periods in/out of treatment...
March 21, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29549214/does-a-prostate-cancer-diagnosis-affect-management-of-pre-existing-diabetes-results-from-pcbase-sweden-a-nationwide-cohort-study
#8
Danielle Crawley, Hans Garmo, Sarah Rudman, Pär Stattin, Björn Zethelius, Jo Armes, Lars Holmberg, Jan Adolfsson, Mieke Van Hemelrijck
OBJECTIVES: Both prostate cancer (PCa) and type 2 diabetes mellitus (T2DM) are increasingly prevalent conditions, which frequently coexist in men. Here, we set out to specifically examine the impact of a PCa diagnosis and its treatment on T2DM treatment. SETTING: This study uses observational data from Prostate Cancer database Sweden Traject. PARTICIPANTS: The study was undertaken in a cohort of 16 778 men with T2DM, of whom 962 were diagnosed with PCa during mean follow-up of 2...
March 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29507533/higher-pharmaceutical-public-expenditure-after-direct-price-control-improved-access-or-induced-demand-the-colombian-case
#9
Sergio I Prada, Victoria E Soto, Tatiana S Andia, Claudia P Vaca, Álvaro A Morales, Sergio R Márquez, Alejandro Gaviria
Background: High pharmaceutical expenditure is one of the main concerns for policymakers worldwide. In Colombia, a middle-income country, outpatient prescription represents over 10% of total health expenditure in the mandatory benefits package (POS), and close to 90% in the complementary government fund (No POS). In order to control expenditure, since 2011, the Ministry of Health introduced price caps on inpatient drugs reimbursements by active ingredient. By 2013, more than 400 different products, covering 80% of public pharmaceutical expenditure were controlled...
2018: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/29493636/-pharmaceutical-preparations-in-the-hospital-analysis-and-in-house-development-of-an-automated-system-of-management
#10
Cinzia Barberini, Enrica Lavezzini, Daniela Zoboli, Corrado Busani
INTRODUCTION: In the past couple of years, the demand of galenic compounds has risen sharply. In order to plan the activity, our team designed and set up a database which stores all the necessary information related to drugs and ingredients. This allows our internal Galenic Laboratory to better manage the pharmaceutical prescriptions for the hospital and the outpatients, optimizing the use of raw materials. METHODS: The application is based on the interconnection of prescription-related aspects (patients' and prescriber's details and prescription information)...
February 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29482599/protocol-mixed-methods-study-to-evaluate-implementation-enforcement-and-outcomes-of-u-s-state-laws-intended-to-curb-high-risk-opioid-prescribing
#11
Emma E McGinty, Elizabeth A Stuart, G Caleb Alexander, Colleen L Barry, Mark C Bicket, Lainie Rutkow
BACKGROUND: The U.S. opioid epidemic has been driven by the high volume of opioids prescribed by healthcare providers. U.S. states have recently enacted four types of laws designed to curb high-risk prescribing practices, such as high-dose and long-term opioid prescribing, associated with opioid-related mortality: (1) mandatory Prescription Drug Monitoring Program (PDMP) enrollment laws, which require prescribers to enroll in their state's PDMP, an electronic database of patients' controlled substance prescriptions, (2) mandatory PDMP query laws, which require prescribers to query the PDMP prior to prescribing an opioid, (3) opioid prescribing cap laws, which limit the dose and/or duration of opioid prescriptions, and (4) pill mill laws, which strictly regulate pain clinics to prevent nonmedical opioid prescribing...
February 26, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29466493/preventable-adverse-drug-events-in-critically-ill-hiv-patients-is-the-detection-of-potential-drug-drug-interactions-a-useful-tool
#12
Grazielle Viana Ramos, André Miguel Japiassú, Fernando Augusto Bozza, Lusiele Guaraldo
OBJECTIVES: The aim of this study was to develop a strategy to identify adverse drug events associated with drug-drug interactions by analyzing the prescriptions of critically ill patients. METHODS: This retrospective study included HIV/AIDS patients who were admitted to an intensive care unit between November 2006 and September 2008. Data were collected in two stages. In the first stage, three prescriptions administered throughout the entire duration of these patients' hospitalization were reviewed, with the Micromedex database used to search for potential drug-drug interactions...
February 19, 2018: Clinics
https://www.readbyqxmd.com/read/29420333/prevalence-of-therapeutic-drug-monitoring-for-lithium-and-the-impact-of-regulatory-warnings-analysis-using-japanese-claims-database
#13
Nobuhiro Ooba, Daisuke Tsutsumi, Naoko Kobayashi, Shinji Hidaka, Hiroyuki Hayashi, Taku Obara, Michihiro Satoh, Kiyoshi Kubota, Noriyasu Fukuoka
BACKGROUND: Therapeutic drug monitoring (TDM) for lithium is recommended in guidelines; however, the prevalence of TDM for lithium is seldom reported. We have therefore investigated the prevalence of TDM for lithium and evaluated the impact of the regulatory warnings requiring routine TDM for lithium. METHODS: Monthly claims data covering around 1.7 million persons aged 20-74 years old during the period January 1, 2005, and March 31, 2015, were evaluated. All patients who had at least one prescription for lithium were selected and included to calculate the annual prevalence of TDM for lithium...
April 2018: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/29403113/antibiotic-distribution-channels-in-thailand-results-of-key-informant-interviews-reviews-of-drug-regulations-and-database-searches
#14
Angkana Sommanustweechai, Sunicha Chanvatik, Varavoot Sermsinsiri, Somsajee Sivilaikul, Walaiporn Patcharanarumol, Shunmay Yeung, Viroj Tangcharoensathien
Objective: To analyse how antibiotics are imported, manufactured, distributed and regulated in Thailand. Methods: We gathered information, on antibiotic distribution in Thailand, in in-depth interviews - with 43 key informants from farms, health facilities, pharmaceutical and animal feed industries, private pharmacies and regulators- and in database and literature searches. Findings: In 2016-2017, licensed antibiotic distribution in Thailand involves over 700 importers and about 24 000 distributors - e...
February 1, 2018: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29385766/benzodiazepines-ii-waking-up-on-sedatives-providing-optimal-care-when-inheriting-benzodiazepine-prescriptions-in-transfer-patients
#15
REVIEW
Jeffrey Guina, Brian Merrill
This review discusses risks, benefits, and alternatives in patients already taking benzodiazepines when care transfers to a new clinician. Prescribers have the decision-sometimes mutually agreed-upon and sometimes unilateral-to continue, discontinue, or change treatment. This decision should be made based on evidence-based indications (conditions and timeframes), comorbidities, potential drug-drug interactions, and evidence of adverse effects, misuse, abuse, dependence, or diversion. We discuss management tools involved in continuation (e...
January 30, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29284347/real-world-treatment-patterns-in-chronic-myeloid-leukemia-patients-newly-initiated-on-tyrosine-kinase-inhibitors-in-an-u-s-integrated-healthcare-system
#16
Nazia Rashid, Han A Koh, Kathy J Lin, Brian Stwalley, Eugene Felber
Purpose To evaluate treatment patterns in patients diagnosed with incident chronic myelogenous leukemia (CML) newly initiating therapy with imatinib, dasatinib, or nilotinib. Patients were followed to determine switching and discontinuation rates. Factors associated with switching or discontinuation from index TKI therapy, reasons for discontinuation based on electronic chart notes, and frequency of laboratory monitoring were assessed during the follow-up period. Methods A retrospective cohort study was conducted in chronic myelogenous leukemia patients aged ≥ 18 years who were identified from the Kaiser Permanente Southern California (KPSC) Cancer Registry database during the study time period of 1 January 2007 to 12 December 2013...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29275945/the-supply-of-prescription-opioids-contributions-of-episodic-care-prescribers-and-high-quantity-prescribers
#17
Todd Schneberk, Brian Raffetto, David Kim, David L Schriger
STUDY OBJECTIVE: We determine episodic and high-quantity prescribers' contribution to opioid prescriptions and total morphine milligram equivalents in California, especially among individuals prescribed large amounts of opioids. METHODS: This was a cross-sectional descriptive analysis of opioid prescribing patterns during an 8-year period using the de-identified Controlled Substance Utilization Review and Evaluation System (CURES) database, the California subsection of the prescription drug monitoring program...
December 21, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29248915/using-controlled-substance-receipt-patterns-to-predict-prescription-overdose-death
#18
Christina T Holt, Kenneth L McCall, Gary Cattabriga, Chunhao Tu, Elenna K Smalley, Stephanie D Nichols
BACKGROUND: This study evaluates complete state data from controlled substance prescribing trends in the prescription monitoring program (PMP) database and their association with the risk of prescription drug overdose death. SUMMARY: Maine PMP records of individuals who died of prescription overdose deaths between 2006 and 2010 were selected (n = 690). For each subject, an age, gender, and residence matched cohort of PMP users in a 50: 1 ratio was identified (n = 34,500)...
2018: Pharmacology
https://www.readbyqxmd.com/read/29240853/the-evaluation-of-medical-inpatients-who-are-admitted-on-long-term-opioid-therapy-for-chronic-pain
#19
Hilary Mosher, Shoshana J Herzig, Itai Danovitch, Christina Boutsicaris, Sameer Hassamal, Karl Wittnebel, Azadeh Dashti, Teryl Nuckols
Individuals who are on long-term opioid therapy (LTOT) for chronic noncancer pain are frequently admitted to the hospital with acute pain, exacerbations of chronic pain, or comorbidities. Consequently, hospitalists find themselves faced with complex treatment decisions in the context of uncertainty about the effectiveness of LTOT as well as concerns about risks of overdose, opioid use disorders, and adverse events. Our multidisciplinary team sought to synthesize guideline recommendations and primary literature relevant to assessing medical inpatients on LTOT, with the objective of assisting practitioners in balancing effective pain treatment and opioid risk reduction...
December 6, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29197326/potentially-inappropriate-prescriptions-for-elderly-people-taking-antidepressant-comparative-tools
#20
Izabela Fulone, Luciane Cruz Lopes
BACKGROUND: The use of psychotropic drugs by elderly people is widely spread around the world, given that prevalence of inappropriate medication is frequent. Strictly speaking, in Brazil, the vulnerable population of elderly people is more likely to use Potentially Inappropriate Psychotropic (PIP) due to the impact of social-economic characteristics, to the Brazilian Public Health System, and to the lack of patient monitoring. However, neither the use pattern nor the prevalence rate of PIP have been studied in Brazil so far...
December 2, 2017: BMC Geriatrics
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