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Julie-Ann Jordan, Judith Wylie, Gerry Mulhern
The present longitudinal study sought to investigate the impact of poor phonology on children's mathematical status. From a screening sample of 256 five-year-olds, 82 children were identified as either typically achieving (TA; N = 31), having comorbid poor phonology and mathematical difficulties (PDMD; N = 31), or having only poor phonology (phonological difficulty, PD; N = 20). Children were assessed on eight components of informal and formal mathematics achievement at ages 5-7 years. PD children were found to have significant impairments in some, mainly formal, components of mathematics by age 7 compared to TA children...
March 2010: British Journal of Developmental Psychology
Elka Stefanova, Aleksandra Potrebic, Ljubomir Ziropadja, Jelena Maric, Ivana Ribaric, Vladimir S Kostic
OBJECTIVE: To estimate the pattern of cognitive impairment in early Parkinson's disease (PD) associated with depression. Also, the prediction of potentially relevant demographic/clinical factors in early PD on cognitive functioning was tested. METHOD: The study comprised 80 consecutive early PD patients (16 with major depression (PDMD), 10 PD patients with dysthimic disorder (PDDD), and 54 nondepressed PD patients (PDND)). Thirty_seven healthy subjects matched for age, gender and education were also included in the study...
October 25, 2006: Journal of the Neurological Sciences
Lilian Dindo, William Coryell
BACKGROUND: Panic disorder (PD) and major depression frequently coexist but the nature of the relationship is controversial. Our aim was to determine if the risk for depression in a proband is influenced by the temporal sequence of comorbid PD and major depression in an affected family member. METHODS: Of participants in a larger study of individuals who had a family, but no personal history of PD, 31 had a first-degree relative with comorbid PD and major depressive disorder (MDD)...
October 1, 2004: Journal of Affective Disorders
E L Giele, J A de Priester, J A Blom, J A den Boer, J M van Engelshoven, A Hasman, M Geerlings
To measure cortical and medullary MR renograms, regions of interest (ROIs) are placed on the kidney in images acquired using dynamic MRI. Since native kidneys move with breathing, and breath-holding techniques are not feasible, movement correction is necessary. In this contribution we compare three correction methods, based on image matching, phase difference movement detection (PDMD), and cross-correlation, respectively. The PDMD-based method showed the best performance and was able to determine kidney movement in our test series in 68% of the scans with no visible deviation, and in 88% of the scans if a one-pixel deviation is considered acceptable...
December 2001: Journal of Magnetic Resonance Imaging: JMRI
A V Zelenin, V A Kolesnikov, O A Tarasenko, R A Shafei, I A Zelenina, V V Mikhailov, M L Semenova, D V Kovalenko, O V Artemyeva, T E Ivaschenko, O V Evgrafov, G Dickson, V S Baranovand
Ballistic transfection, based on cell and tissue bombardment by the tungsten and gold microparticles covered with the gene DNA, was used for the delivery of a bacterial beta-galactosidase and a full-length cDNA copy of the human dystrophin genes into mouse skeletal muscles. CMV-lacZ, SV40-lacZ, LTR-lacZneo and full-length cDNA dystrophin (pDMD-1, approximately 16 kb) in eukaryotic expression vector pJ OMEGA driven by mouse leukaemia virus promotor (pMLVDy) were used throughout the studies. Musculus glutaeus superficialis of C57BL/6J and quadriceps femoris of mdx male mice were opened surgically under anesthesia and bombarded by means of the gene-gun technique originally developed by us...
September 8, 1997: FEBS Letters
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