keyword
MENU ▼
Read by QxMD icon Read
search

Extreme longevity

keyword
https://www.readbyqxmd.com/read/28935556/altitudinal-variation-and-bio-climatic-variables-influencing-the-potential-distribution-of-culicoides-orientalis-macfie-1932-suspected-vector-of-bluetongue-virus-across-the-north-eastern-himalayan-belt-of-sikkim
#1
Emon Mukhopadhyay, Surajit Hazra, Goutam Kumar Saha, Dhriti Banerjee
Culicoides orientalis was first recorded from Sikkim, in the year 1963, but no evidence based disease outbreak were available. In the last 50 years, 260 Bluetongue disease outbreaks caused by Culicoides species have been evidenced from India. Moreover, in recent years with increase of average temperature worldwide and increase in longevity of arthropod vectors like Culicoides along with a geographical range shift to new suitable warmer regions has increased the potentiality of vector borne disease outbreak throughout the world...
September 18, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28928669/nature-s-electric-potential-a-systematic-review-of-the-role-of-bioelectricity-in-wound-healing-and-regenerative-processes-in-animals-humans-and-plants
#2
REVIEW
Sheena E B Tyler
Natural endogenous voltage gradients not only predict and correlate with growth and development but also drive wound healing and regeneration processes. This review summarizes the existing literature for the nature, sources, and transmission of information-bearing bioelectric signals involved in controlling wound healing and regeneration in animals, humans, and plants. It emerges that some bioelectric characteristics occur ubiquitously in a range of animal and plant species. However, the limits of similarities are probed to give a realistic assessment of future areas to be explored...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28915360/risk-factors-for-reoperation-and-performance-based-outcomes-after-operative-fixation-of-foot-fractures-in-the-professional-athlete-a-cross-sport-analysis
#3
Sameer Singh, Kevin Larkin, Anish Kadakia, Wellington Hsu
BACKGROUND: Professional athletes are predisposed to fractures of the foot due to large stresses placed on the lower extremity. These players are concerned with efficiently returning to play at a high level. Return-to-play rates after operative treatment have been previously reported, yet performance outcomes after such treatment are generally unknown in this population. HYPOTHESIS: Overall, professional athletes sustaining a foot fracture would return to play at high rates with little impact on post-operative performance or league participation...
September 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28900276/highly-variable-lifespan-in-an-annual-reptile-labord-s-chameleon-furcifer-labordi
#4
Falk Eckhardt, Peter M Kappeler, Cornelia Kraus
Among tetrapods, the current record holder for shortest lifespan is Labord's chameleon, Furcifer labordi. These reptiles from the arid southwest of Madagascar have a reported lifespan of 4-5 months during the annual rainy season and spend the majority of their life (8-9 months) as a developing embryo. This semelparous, annual life history is unique among tetrapods, but only one population (Ranobe) in the southernmost distribution range has been studied. We therefore investigated the potential for environmentally-dependent variability in lifespan in a population in Kirindy Forest, which has a much longer warm rainy season...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28899752/are-adult-life-history-traits-in-oriental-fruit-moth-affected-by-a-mild-pupal-heat-stress
#5
Jincheng Zheng, Xiongbin Cheng, Ary A Hoffmann, Bo Zhang, Chun-Sen Ma
Thermal stress at one life stage can affect fitness at a later stage in ectotherms with complex life cycles. Most relevant studies have focused on extreme stress levels, but here we also show substantial fitness effects in a moth when pupae are exposed to a relatively mild and sublethal heat stress. We consider the impact of a 35°C heat stress of 2h in three geographically separate populations of the oriental fruit moth (OFM, Grapholita molesta) from northern, middle and southern China. Heat stress negatively affected fecundity but increased adult heat resistance and adult longevity...
September 9, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28851819/o2-binding-and-co2-sensitivity-in-hemoglobins-of-subterranean-african-mole-rats
#6
Roy E Weber, Jennifer U M Jarvis, Angela Fago, Nigel C Bennett
Inhabiting deep and sealed subterranean burrows, mole rats exhibit a remarkable suite of specializations, including eusociality (living in colonies with single breeding queens), extraordinary longevity, cancer immunity and poikilothermy, and extreme tolerance of hypoxia and hypercapnia.With little information available on adjustments in hemoglobin (Hb) function that may mitigate the impact of exogenous and endogenous constraints on the uptake and internal transport of O2, we measured hematological characteristics, as well as Hb-O2 binding affinities and their sensitivities to pH (Bohr effect), CO2, temperature and 2,3 diphosphoglycerate (DPG, the major allosteric modulator of Hb-O2 affinity in the red cells) in four social and two solitary species of African mole rats (family Bathyergidae) originating from different biomes and soil types across Central and Southern Africa...
August 29, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28837599/hsf-1-is-a-regulator-of-mirna-expression-in-caenorhabditis-elegans
#7
Jessica Brunquell, Alana Snyder, Feng Cheng, Sandy D Westerheide
The ability of an organism to sense and adapt to environmental stressors is essential for proteome maintenance and survival. The highly conserved heat shock response is a survival mechanism employed by all organisms, including the nematode Caenorhabditis elegans, upon exposure to environmental extremes. Transcriptional control of the metazoan heat shock response is mediated by the heat shock transcription factor HSF-1. In addition to regulating global stress-responsive genes to promote stress-resistance and survival, HSF-1 has recently been shown to regulate stress-independent functions in controlling development, metabolism, and longevity...
2017: PloS One
https://www.readbyqxmd.com/read/28797827/interaction-between-mtor-pathway-inhibition-and-autophagy-induction-attenuates-adriamycin-induced-vascular-smooth-muscle-cell-senescence-through-decreased-expressions-of-p53-p21-p16
#8
Jin Young Sung, Kyung Young Lee, Jae-Ryong Kim, Hyoung Chul Choi
Cellular senescence is related to aging and extremely stable proliferative arrest with active metabolism. Senescent cells can activate mammalian target of rapamycin (mTOR) pathway, which plays a crucial role in the regulation of cell metabolism, cellular growth, and autophagy in senescence-associated cardiovascular diseases. Therefore, we examined whether mTOR pathway could induce cellular senescence by inhibition of autophagy in vascular smooth muscle cells (VSMCs). We found that adriamycin-induced VSMC senescence is accompanied by increased activity of mTOR, a major controller of cell growth and a negative regulator of autophagy...
August 7, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28753971/spatio-temporal-variation-of-longevity-clusters-and-the-influence-of-social-development-level-on-lifespan-in-a-chinese-longevous-area-1982-2010
#9
Jian Qin, Guoqi Yu, Tianlong Xia, You Li, Xue Liang, Peng Wei, Bingshuang Long, Mingzhi Lei, Xiao Wei, Xianyan Tang, Zhiyong Zhang
The study aims to determine the spatial and temporal variation of a longevous region and explore the correlation between longevity and socioeconomic development. Population data at the township level were obtained from the last four population censuses (1982-2010). Five main lifespan indicators and the Human Development Index (HDI) were calculated. Getis-Ord G*, Gravity modeling, and Pearson's r between lifespan indicators and HDI were applied. In this study, a stable longevous gathering area was discovered in Hechi during different periods...
July 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28734548/ubiquitin-like-modifications-in-the-dna-damage-response
#10
REVIEW
Zhifeng Wang, Wei-Guo Zhu, Xingzhi Xu
Genomic DNA is damaged at an extremely high frequency by both endogenous and environmental factors. An improper response to DNA damage can lead to genome instability, accelerate the aging process and ultimately cause various human diseases, including cancers and neurodegenerative disorders. The mechanisms that underlie the cellular DNA damage response (DDR) are complex and are regulated at many levels, including at the level of post-translational modification (PTM). Since the discovery of ubiquitin in 1975 and ubiquitylation as a form of PTM in the early 1980s, a number of ubiquitin-like modifiers (UBLs) have been identified, including small ubiquitin-like modifiers (SUMOs), neural precursor cell expressed, developmentally down-regulated 8 (NEDD8), interferon-stimulated gene 15 (ISG15), human leukocyte antigen (HLA)-F adjacent transcript 10 (FAT10), ubiquitin-fold modifier 1 (UFRM1), URM1 ubiquitin-related modifier-1 (URM1), autophagy-related protein 12 (ATG12), autophagy-related protein 8 (ATG8), fan ubiquitin-like protein 1 (FUB1) and histone mono-ubiquitylation 1 (HUB1)...
July 11, 2017: Mutation Research
https://www.readbyqxmd.com/read/28707767/if-why-and-when-subjective-well-being-influences-health-and-future-needed-research
#11
Ed Diener, Sarah D Pressman, John Hunter, Desiree Delgadillo-Chase
We review evidence on whether subjective well-being (SWB) can influence health, why it might do so, and what we know about the conditions where this is more or less likely to occur. This review also explores how various methodological approaches inform the study of the connections between subjective well-being and health and longevity outcomes. Our review of this growing literature indicates areas where data are substantial and where much more research is needed. We conclude that SWB can sometimes influence health, and review a number of reasons why it does so...
July 2017: Applied Psychology. Health and Well-being
https://www.readbyqxmd.com/read/28699149/is-the-clavicula-pro-humero-technique-of-value-for-reconstruction-after-resection-of-the-proximal-humerus-in-children
#12
Dominique Barbier, Benoît De Billy, Philippe Gicquel, Sophie Bourelle, Pierre Journeau
BACKGROUND: There are several options for reconstruction of proximal humerus resections after wide resection for malignant tumors in children. The clavicula pro humero technique is a biologic option that has been used in the past, but there are only scant case reports and small series that comment on the results of the procedure. Because the longevity of children mandates a reconstruction with potential longevity not likely to be achieved by other techniques, the clavicula pro humero technique may be a potential option in selected patients...
July 11, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28689349/extreme-longevity-in-a-deep-sea-vestimentiferan-tubeworm-and-its-implications-for-the-evolution-of-life-history-strategies
#13
Alanna Durkin, Charles R Fisher, Erik E Cordes
The deep sea is home to many species that have longer life spans than their shallow-water counterparts. This trend is primarily related to the decline in metabolic rates with temperature as depth increases. However, at bathyal depths, the cold-seep vestimentiferan tubeworm species Lamellibrachia luymesi and Seepiophila jonesi reach extremely old ages beyond what is predicted by the simple scaling of life span with body size and temperature. Here, we use individual-based models based on in situ growth rates to show that another species of cold-seep tubeworm found in the Gulf of Mexico, Escarpia laminata, also has an extraordinarily long life span, regularly achieving ages of 100-200 years with some individuals older than 300 years...
August 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28649103/-aging-and-homeostasis-biomedical-peculiarities-of-semi-supercentenarians
#14
Yasumichi Arai
Semi-supercentenarians, or people who reach 105 years of age, are regarded as model cases for 'successful ageing'. Semi-supercentenarians maintain capability and cognition for longer than the centenarians who died between 100-104 years of age, together with postponed frailty or age-related diminution of multiple organ reserve. Understanding the biological factors determining extreme longevity and compression of morbidity might help to achieve extended healthy life span for the wider population.
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28646299/effective-combined-water-and-sideband-suppression-for-low-speed-tissue-and-in-vivo-mas-nmr
#15
Yalda Liaghati Mobarhan, Jochem Struppe, Blythe Fortier-McGill, André J Simpson
High-resolution magic angle spinning (HR-MAS) NMR is a powerful technique that can provide metabolic profiles and structural constraints on intact biological and environmental samples such as cells, tissues and living organisms. However, centripetal force from fast spinning can lead to a loss of sample integrity. In analyses focusing on structural organization, metabolite compartmentalization or in vivo studies, it is critical to keep the sample intact. As such, there is growing interest in slow spinning studies that preserve sample longevity...
August 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28637252/wheat-seed-weight-and-quality-differ-temporally-in-sensitivity-to-warm-or-cool-conditions-during-seed-development-and-maturation
#16
M Nasehzadeh, R H Ellis
Background and aims: Short periods of extreme temperature may affect wheat (Triticum aestivum) seed weight, but also quality. Temporal sensitivity to extreme temperature during seed development and maturation was investigated. Methods: Plants of 'Tybalt' grown at ambient temperature were moved to growth cabinets at 29/20°C or 34/20°C (2010), or 15/10°C or 34/20°C (2011), for successive 7-d periods from 7 DAA (days after anthesis) onwards, and also 7-65 DAA in 2011...
September 1, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28601155/boar-genotype-as-a-factor-shaping-age-related-changes-in-semen-parameters-and-reproduction-longevity-simulations
#17
Damian Knecht, Anna Jankowska-Mąkosa, Kamil Duziński
The aim of this study was a detailed analysis of the boar genotypes used in AI stations with an indication of their production capacity, including age and a precise analysis of their culling time and reason. The study included 334 boars: 81 Polish Large White (PLW), 108 Polish Landrace (PL), 49 Pietrain (P), 56 Duroc × Pietrain (D × P) and 40 Hampshire × Pietrain (H × P). Semen volume, spermatozoa concentration, total number of spermatozoa, number of motile spermatozoa, and number of insemination doses were analyzed...
August 2017: Theriogenology
https://www.readbyqxmd.com/read/28599250/evaluation-of-mir-15a-and-mir-16-1-as-prognostic-biomarkers-in-chronic-lymphocytic-leukemia
#18
REVIEW
Tatiane Vieira Braga, Fernanda Cristina Gontijo Evangelista, Lorena Caixeta Gomes, Sérgio Schusterschitz da Silva Araújo, Maria das Graças Carvalho, Adriano de Paula Sabino
Chronic lymphocytic leukemia (CLL) is a B lineage neoplasm, characterized by the accumulation of B lymphocytes of great longevity, and usually develops as a result of the inhibition of apoptosis. Clinical evolution is extremely variable amongst affected individuals with survival ranging from a few months in aggressive cases, to a few decades in cases of indolent CLL. The identification of new prognostic factors, apart from clinical staging, has been an important research topic aiming at a better understanding of CLL...
August 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28587826/safety-assessment-of-cultivated-fruiting-body-of-ophiocordyceps-sinensis-evaluated-through-subacute-toxicity-in-rats
#19
Shin Yee Fung, Sook Shien Lee, Nget Hong Tan, Jayalakshmi Pailoor
ETHNOPHARMACOLOGICAL RELEVANCE: Ophiocordyceps sinensis (Berk.) G.H. Sung, J.M. Sung, Hywel-Jones & Spatafora is one of the most renowned traditional Chinese medicine used as tonic, renal, respiratory and reproductive health, promote longevity and overall improvement in quality of life. Natural production of O. sinensis is limited due to its extreme specificity in host range and confined geographic distribution. Therefore, cultivation of the fungus was developed to meet high demand for commercialization as nutraceutical...
July 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28510785/the-impact-of-leisure-on-mental-health-of-sardinian-elderly-from-the-blue-zone-evidence-for-ageing-well
#20
Maria Chiara Fastame, Paul Kenneth Hitchcott, Maria Pietronilla Penna
BACKGROUND: There has been scientific interest in the Sardinia population for a number of years and for a variety of reasons, including its extreme longevity. This is especially prevalent in the central-eastern region of the island, where a blue zone region has been precisely delineated. AIMS: The present study examines the influence of leisure activities on psychological well-being and depressive symptoms in elderly individuals living in the blue zone region of inner Sardinia...
May 16, 2017: Aging Clinical and Experimental Research
keyword
keyword
106438
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"