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https://www.readbyqxmd.com/read/28931449/frailty-and-depression-in-centenarians
#1
Oscar Ribeiro, Natália Duarte, Laetitia Teixeira, Constança Paúl
BACKGROUND: Physical frailty and depression are common comorbid conditions that have important impact on older adults. Few studies however have examined their co-occurrence in centenarians. This paper explores the relationship between the two conditions and the most characteristic depressive symptoms associated with the frailty syndrome. METHODS: Data come from two Portuguese Centenarian Studies. Frailty was measured using Fried's phenotype, which includes at least three clinical signs: exhaustion, weight loss, weakness, slowness, and low physical activity level; the Geriatric Depression Scale was used to assess depression...
September 21, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28923181/centenarians-in-europe
#2
Laetitia Teixeira, Lia Araújo, Daniela Jopp, Oscar Ribeiro
OBJECTIVES: The group of individuals aged 80 and over is growing faster than other segments of the population, and within this group the number of centenarians has risen exponentially worldwide. This paper reports the numbers of centenarians (total, and ratio relative to total population) in 32 European countries and their key characteristics: gender distribution, level of education, and type of residence. STUDY DESIGN: Population based study. MEASURES: We used national census data collected in 2011 for individuals aged 100 and over living in Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland and the UK...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28910949/-china-hainan-centenarian-cohort-study-study-design-and-preliminary-results
#3
Y He, F X Luan, Y Yao, S S Yang, H G Xie, J Li, M Liu, J H Wang, L Wu, Q Zhu, X P Chen, C X Ning, L N Wang, X Y Li, S B Zhang, F Zhang, Y L Zhao
Objective: To investigate the health status, functional ability, mental psychology, health care and other longevity-related characteristics of individuals aged ≥100 years as well as risk factors in Hainan province, China. Methods: China Hainan Centenarian Cohort Study (CHCCS) is a community-based, prospective cohort study to establish multi-dimensional database consisting of questionnaire findings, anthropometric parameters and biological specimens as well as imaging features. With the household registration information provided by the Department of Civil Affairs of Hainan province, a baseline survey was conducted in centenarians in 18 counties in Hainan with the oldest old in 5 counties as controls between 2014 and 2017...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28904969/sociodemographic-and-clinical-characteristics-of-centenarians-in-mexico-city
#4
Valdés-Corchado Pedro, Ruiz-Hernández Arturo, Pérez-Moreno Alejandro, Rosas-Carrasco Oscar
BACKGROUND: There is little evidence about the demography and health status of adults aged 100 years and over in Latin America and there are no studies in Mexico. OBJECTIVES: To describe the demographic characteristics and health status of centenarians residing in Mexico City. METHODS: This is a cross-sectional study using a population base of 393 community-dwelling centenarians in Mexico City. A comprehensive geriatric assessment was performed, including demographic information and health status...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28898613/functional-sensorial-mobility-and-communication-difficulties-in-the-portuguese-oldest-old-80
#5
Daniela Brandão, Óscar Ribeiro, Constança Paúl
INTRODUCTION: The ageing of populations is evident in most developed countries, and the oldest old group is one of the segments with the fastest growing. The aim of this paper is to examine sociodemographic and health related characteristics of the portuguese oldest old, using a census-based approach. MATERIAL AND METHODS: A descriptive study considering all residents aged 80 years and older at the time of the 2011 Census (n = 532 219) was conducted. Information on sociodemographic characteristics, sensory functions (seeing, hearing), functional status (walking/climbing stairs, bathing/dressing alone), cognition (memory/concentration), and communication (understanding others/being understood) as assessed by the Portuguese census official questionnaires were analyzed...
June 30, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28893250/association-between-dietary-patterns-and-cognitive-function-among-70-year-old-japanese-elderly-a-cross-sectional-analysis-of-the-sonic-study
#6
Hitomi Okubo, Hiroki Inagaki, Yasuyuki Gondo, Kei Kamide, Kazunori Ikebe, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Satoshi Sasaki, Takeshi Nakagawa, Mai Kabayama, Ken Sugimoto, Hiromi Rakugi, Yoshinobu Maeda
BACKGROUND: An increasing number of studies in Western countries have shown that healthy dietary patterns may have a protective effect against cognitive decline and dementia. However, information on this relationship among non-Western populations with different cultural settings is extremely limited. We aim to examine the relationship between dietary patterns and cognitive function among older Japanese people. METHODS: This cross-sectional study included 635 community-dwelling people aged 69-71 years who participated in the prospective cohort study titled Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC)...
September 11, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28883855/five-gene-variants-in-nonagenarians-centenarians-and-average-individuals
#7
Vana Kolovou, Helen Bilianou, Vasiliki Giannakopoulou, Petros Kalogeropoulos, Constantinos Mihas, Markos Kouris, Dennis V Cokkinos, Maria Boutsikou, Ioannis Hoursalas, Sophie Mavrogeni, Niki Katsiki, Genovefa Kolovou
INTRODUCTION: Genetic factors contribute to the variation of human life span which is believed to be more profound after 85 years of age. The aim of the present study was to evaluate the frequency of 5 gene polymorphisms between nonagenarians, centenarians and average individuals. MATERIAL AND METHODS: Single nucleotide polymorphisms (SNPs) of telomerase reverse transcriptase (TERT; rs2736098), insulin-like growth factor-1 binding protein-3 (IGFBP3; A-202C, rs2857744), fork-head box O3A (FOXO3A; rs13217795 and rs2764264) factor and adiponectin (ADIPOQ; rs2241766) were evaluated in 405 individuals: n = 256 nonagenarians and centenarians (study group) and n = 149 average lifespan individuals (control group aged 18 - < 80 years)...
August 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28856487/determinants-of-health%C3%A2-care-costs-in-the-senior-elderly-age-comorbidity-impairment-or-proximity-to-death
#8
Nisha C Hazra, Caroline Rudisill, Martin C Gulliford
Ageing is assumed to be accompanied by greater health care expenditures but the association is also viewed as a 'red herring'. This study aimed to evaluate whether age is associated with health care costs in the senior elderly, using electronic health records for 98,220 participants aged 80 years and over registered with the UK Clinical Practice Research Datalink and linked Hospital Episode Statistics (2010-2014). Annual costs of health care utilization were estimated from a two-part model; multiple fractional polynomial models were employed to evaluate the non-linear association of age with predicted health care costs while also controlling for comorbidities, impairments, and death proximity...
August 30, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28852094/unraveling-the-gut-microbiome-of-the-long-lived-naked-mole-rat
#9
Tewodros Debebe, Elena Biagi, Matteo Soverini, Susanne Holtze, Thomas Bernd Hildebrandt, Claudia Birkemeyer, Dereje Wyohannis, Alemayehu Lemma, Patrizia Brigidi, Vulk Savkovic, Brigitte König, Marco Candela, Gerd Birkenmeier
The naked mole-rat (Heterocephalus glaber) is a subterranean mouse-sized African mammal that shows astonishingly few age-related degenerative changes and seems to not be affected by cancer. These features make this wild rodent an excellent model to study the biology of healthy aging and longevity. Here we characterize for the first time the intestinal microbial ecosystem of the naked mole-rat in comparison to humans and other mammals, highlighting peculiarities related to the specific living environment, such as the enrichment in bacteria able to utilize soil sulfate as a terminal electron acceptor to sustain an anaerobic oxidative metabolism...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28835873/hip-fractures-in-centenarians-has-care-improved-in-the-national-hip-fracture-database-era
#10
Alastair G Dick, Dominic Davenport, Mohit Bansal, Therese S Burch, Max R Edwards
INTRODUCTION: The number of centenarians in the United Kingdom is increasing. An associated increase in the incidence of hip fractures in the extreme elderly population is expected. The National Hip Fracture Database (NHFD) initiative was introduced in 2007 aiming to improve hip fracture care. There is a paucity of literature on the outcomes of centenarians with hip fractures since its introduction. The aim of this study is to report our experience of hip fractures in centenarians in the era since the introduction of the NHFD to assess outcomes in terms of mortality, time to surgery, length of stay, and complications...
September 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28760137/prevalence-and-clinical-profile-of-metabolic-syndrome-in-longevity-study-from-guangxi-zhuang-autonomous-region-china
#11
Xianghua He, Wei Zhang, Guofang Pang, Yuan Lv, Caiyou Hu, Ze Yang
BACKGROUND: Metabolic syndrome (MetS) was a risk factor for cardiovascular diseases, yet the prevalence of MetS among nonagenarians and centenarians was rarely reported. Here we investigated the prevalence of MetS and its components among nonagenarians and centenarians in our Zhuang population from Bama, Guangxi Zhuang Autonomous Region, China. METHOD: In Bama area, there registered 881 individuals who lived more than 90 years old in 269,800 local residents and our study involved 307 long-lived participants and 486 local younger (35-68 years) persons, as controls...
July 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28754532/centenarians-maintain-mirna-biogenesis-pathway-while-it-is-impaired-in-octogenarians
#12
C Borrás, E Serna, J Gambini, M Inglés, J Vina
Centenarians but not octogenarians up regulate the expression of miRNAs, as we previously reported. We have looked into miRNA biogenesis. We show that RNA POL II, DROSHA, EXPORTIN 5 and DICER, are up-regulated in centenarians compared with octogenarians. Furthermore, factors involved in the control of these miRNAs biogenesis genes are also up-regulated in centenarians. Therefore, the up-regulation of miRNA expression in centenarians can be explained in part because miRNA biogenesis pathway is depressed in octogenarians (ordinary aging) while it is maintained in centenarians (extraordinary aging)...
July 25, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28741698/the-relationship-between-vision-impairment-and-well-being-among-centenarians-findings-from-the-georgia-centenarian-study
#13
Aya Toyoshima, Peter Martin, Shinichi Sato, Leonard W Poon
OBJECTIVE: The current study evaluated the visual function among centenarians and assessed the relationship between vision, social support, and well-being. METHODS: This study used the data set of the Georgia Centenarian Study including 106 centenarians (18 men and 88 women). We used scores of the Snellen chart for objective vision and self-reports for subjective vision. Social support, depression, and loneliness were also assessed. RESULTS: Approximately 75% of the centenarians showed some level of objective visual impairment, and 56% of them reported that they had visual impairment...
July 25, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28728345/safety-of-percutaneous-endoscopic-gastrostomy-tubes-in-centenarian-patients
#14
Zain A Sobani, Kevin Tin, Steven Guttmann, Anna A Abbasi, Ira Mayer, Yuriy Tsirlin
Background/Aims: Percutaneous endoscopic gastrostomy (PEG) is a relatively safe procedure; however, no study has evaluated the safety of PEG tube placement in patients over the age of 100 years. Methods: We conducted a retrospective review of patient records for patients who underwent PEG tube placement. Thirty patients aged 100 years and older were identified and a random sample of 275 patients was selected for comparison. Results: The mean age of the patients was 80...
July 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28682113/subjective-well-being-in-centenarians-a-comparison-of-japan-and-the-united-states
#15
Takeshi Nakagawa, Jinmyoung Cho, Yasuyuki Gondo, Peter Martin, Mary Ann Johnson, Leonard W Poon, Nobuyoshi Hirose
OBJECTIVE: The present study examined the cultural differences and similarities in the levels and predictors of subjective well-being in Japanese and American centenarians. METHOD: We analyzed data on cognitively intact Japanese (N = 59) and American (N = 125) participants from the Tokyo and Georgia Centenarian Studies, respectively. The Philadelphia Geriatric Center Morale Scale was used to measure subjective well-being, while sociodemographic, social, and health resources were assessed as potential predictors...
July 6, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28680504/association-between-handgrip-strength-walking-age-related-illnesses-and-cognitive-status-in-a-sample-of-portuguese-centenarians
#16
Maria Vaz-Patto, Belén Bueno, Óscar Ribeiro, Laetitia Teixeira, Rosa Marina Afonso
BACKGROUND: Centenarians are a growing population in Europe and present significant variability in motor and cognitive functions. The aim of our study was to characterize health status, as well as cognitive and motor functions in a group of Portuguese centenarians. In addition, our study also aimed at analyzing the relationship between cognitive functions and the burden of diseases affecting the elderly. METHODS: Fifty-two centenarians were evaluated using the Mini-Mental State Examination, short version...
2017: European Review of Aging and Physical Activity
https://www.readbyqxmd.com/read/28678129/short-term-outcomes-following-hip-fractures-in-patients-at-least-100-years-old
#17
Arthur Manoli, Adam Driesman, Rebecca A Marwin, Sanjit Konda, Philipp Leucht, Kenneth A Egol
BACKGROUND: The number of hip fractures is rising as life expectancy increases. As such, the number of centenarians sustaining these fractures is also increasing. The purpose of this study was to determine whether patients who are ≥100 years old and sustain a hip fracture fare worse in the hospital than those who are younger. METHODS: Using a large database, the New York Statewide Planning and Research Cooperative System (SPARCS), we identified patients who were ≥65 years old and had been treated for a hip fracture over a 12-year period...
July 5, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28673761/primary-percutaneous-coronary-intervention-as-treatment-for-st-elevation-myocardial-infarction-in-a-centenarian-choosing-carefully
#18
Justin M Cloutier, Shelley Zieroth, Basem Elbarouni
We report on a 105-year-old woman presenting with inferior ST-elevation myocardial infarction (STEMI). She was managed with primary percutaneous intervention (PCI) to the right coronary artery with a single bare-metal stent. There were no acute complications, although she experienced delirium and functional decline requiring prolonged hospital admission. She was discharged home and celebrated her 106th birthday. This report describes the oldest centenarian with STEMI found in the literature and managed with PCI...
August 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28651996/centenarians-as-a-21st-century-healthy-aging-model-a-legacy-of-humanity-and-the-need-for-a-world-wide-consortium-wwc100
#19
EDITORIAL
Claudio Franceschi, Giuseppe Passarino, Daniela Mari, Daniela Monti
No abstract text is available yet for this article.
July 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/28649103/-aging-and-homeostasis-biomedical-peculiarities-of-semi-supercentenarians
#20
Yasumichi Arai
Semi-supercentenarians, or people who reach 105 years of age, are regarded as model cases for 'successful ageing'. Semi-supercentenarians maintain capability and cognition for longer than the centenarians who died between 100-104 years of age, together with postponed frailty or age-related diminution of multiple organ reserve. Understanding the biological factors determining extreme longevity and compression of morbidity might help to achieve extended healthy life span for the wider population.
2017: Clinical Calcium
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