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https://www.readbyqxmd.com/read/29688925/interdisciplinary-dialogue-is-needed-when-defining-perioperative-recommendations-conflicting-guidelines-for-anesthetizing-patients-for-pilonidal-surgery
#1
Roland E Andersson, Dietrich Doll, Verena K Stauffer, Andreas P Vogt, Steven D Boggs, Markus M Luedi
National or international guidelines can help surgeons and anesthesiologists make treatment decisions, but the existence of conflicting recommendations can hinder treatment rather than helping. A case in point is the treatment of pilonidal sinus disease, a chronic subcutaneous infection located in the sacrococcygeal area. Its incidence is rising, reaching almost 100/100,000 inhabitants. Three surgical societies have proposed guidelines for treating the disease, but these guidelines vary greatly in their approach to anesthesia...
April 23, 2018: A&A practice
https://www.readbyqxmd.com/read/29627583/hispanic-ethnicity-stress-psychophysiology-and-paradoxical-health-outcomes-a-review-with-conceptual-considerations-and-a-call-for-research
#2
REVIEW
John M Ruiz, David Sbarra, Patrick R Steffen
It is not wise to generalize psychophysiological findings from WEIRD (Western, Educated, Industrialized, Rich, Democratic) samples to all people and yet this occurs frequently in research. Case-in-point is our understanding of psychophysiological responses to stress which suggest universality despite our knowledge that these pathways are moderated by factors such as ethnicity and culture. Here we discuss the epidemiological phenomenon commonly referred to as the Hispanic health paradox to illustrate the importance of culture in understanding stress...
April 5, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29622425/myocardial-regeneration-therapy-in-heart-failure-current-status-and-future-therapeutic-implications-in-clinical-practice
#3
Marko Banovic, Maja Pusnik-Vrckovnik, Eleni Nakou, Panos Vardas
Despite multiple treatment regimens the morbidity and mortality of patients with advanced heart failure (HF) have reached pandemic proportions. In an effort to address the root cause of the problem, curative strategies are increasingly being considered. A case in point is the evolution of regenerative medicine technologies aiming to halt or even reverse progressive organ deterioration in the HF setting. The prevailing unmet clinical needs in HF therapy have provided a major incentive for the development of cell-based treatment strategies, which have shown encouraging results in experimental studies...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29603844/how-can-changing-the-bridgehead-affect-the-properties-of-tripodal-ligands
#4
Alex J Plajer, Annie L Colebatch, Felix J Rizzuto, Patrick Pröhm, Andrew D Bond, Raúl García-Rodríguez, Dominic Wright
Although a multitude of studies have explored the coordination chemistry of classical tripodal ligands containing a range of main group bridgehead atoms or groups, there has been no clear answer to the question of how underlying periodic trends affect ligand character and reactivity within a single ligand family. In addition to standard steric and electronic modification of the organic groups themselves, this issue is of key importance in the design and tuning of C3-symmetric tripodal ligands for applications in catalysis...
March 30, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29584542/toward-decentralized-agrigenomic-surveillance-a-polymerase-chain-reaction-restriction-fragment-length-polymorphism-approach-for-adaptable-and-rapid-detection-of-user-defined-fungal-pathogens-in-potato-crops
#5
Manousos E Kambouris, Yiannis Manoussopoulos, Stavroula Kritikou, Aphroditi Milioni, Spyridon Mantzoukas, Aristea Velegraki
Agrigenomics is one of the emerging focus areas for omics sciences. Yet, agrigenomics differs from medical omics applications such as pharmacogenomics and precision medicine, by virtue of vastly distributed geography of applications at the intersection of agriculture, nutrition, and genomics research streams. Crucially, agrigenomics can address diagnostics and safety surveillance needs in remote and rural farming communities or decentralized food, crop, and environmental monitoring programs for prompt, selective, and differential identification of pathogens...
March 27, 2018: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29573259/transmission-human-population-and-pathogenicity-the-ebola-case-in-point
#6
Rafael Delgado, Fernando Simón
The 2013-2016 Ebola outbreak in West Africa has been the largest ever of a known disease in a new context that produced an unprecedented impact and is changing the international approach to responding to public health emergencies. The unprecedented scale of the outbreak, the use of advanced technology for detecting and characterizing the infectious agent, along with the opportunity to treat patients in modern facilities have greatly increased our knowledge of the disease and its transmission. Also, for the first time, an important international effort has been deployed to control the spread of the epidemic by providing care to patients and by adopting basic measures of public health control...
March 2018: Microbiology Spectrum
https://www.readbyqxmd.com/read/29544356/coaching-in-early-physical-therapy-intervention-the-copca-program-as-an-example-of-translation-of-theory-into-practice
#7
Schirin Akhbari Ziegler, Tineke Dirks, Mijna Hadders-Algra
BACKGROUND: Coaching is en vogue in pediatric physiotherapy, but often applied rather unspecific and undefined. METHODS: This paper aims to describe coaching in early physiotherapy intervention, taking the specific coaching approach of the family-centered program "COPing with and CAring for infants with special needs" (COPCA) as a case in point. RESULTS: The theoretical underpinnings of coaching in COPCA, including a meta-model, family-centered practice, the Neuronal Group Selection Theory and the goal-oriented coaching approach, are discussed...
March 16, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29540945/split-notochord-syndrome-a-case-in-point
#8
Camila Soares Moreira de Sousa, Bárbara Bezerra de Castro, Carla Lorena Vasques Mendes de Miranda, Breno Braga Bastos, Marcelo Coelho Avelino
No abstract text is available yet for this article.
January 2018: Radiologia Brasileira
https://www.readbyqxmd.com/read/29509044/representing-and-organizing-information-to-describe-the-lived-experience-of-health-from-a-personal-factors-perspective-in-the-light-of-the-international-classification-of-functioning-disability-and-health-icf-a-discussion-paper
#9
Szilvia Geyh, Urban Schwegler, Claudio Peter, Rachel Müller
PURPOSE: To discuss the representation and organization of information describing persons' lived experience of health from a personal factors perspective in the light of the International Classification of Functioning, Disability and Health, using spinal cord injury as a case in point for disability. METHODS: The scientific literature was reviewed, discussion rounds conducted, and qualitative secondary analyses of data carried out using an iterative inductive-deductive approach...
March 6, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29490695/health-disparities-monitoring-in-the-u-s-lessons-for-monitoring-efforts-in-israel-and-other-countries
#10
Kathleen Abu-Saad, Shlomit Avni, Ofra Kalter-Leibovici
BACKGROUND: Health disparities are a persistent problem in many high-income countries. Health policymakers recognize the need to develop systematic methods for documenting and tracking these disparities in order to reduce them. The experience of the U.S., which has a well-established health disparities monitoring infrastructure, provides useful insights for other countries. MAIN BODY: This article provides an in-depth review of health disparities monitoring in the U...
February 28, 2018: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29473220/cost-shifting-and-other-perverse-incentives-in-biodiversity-offsetting-in-india
#11
Divya Narain, Martine Maron
Biodiversity offsetting aims to compensate for development-induced biodiversity loss through commensurate conservation gains and is gaining traction among governments and businesses. However, cost shifting (i.e., diversion of offset funds to other conservation programs) and other perverse incentives can undermine the effectiveness of biodiversity offsetting. Additionality-the requirement that biodiversity offsets result in conservation outcomes that would not have been achieved otherwise-is fundamental to biodiversity offsetting...
February 23, 2018: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29469738/dermatologic-manifestations-of-acromegaly-a-case-in-point-and-a-focused-review
#12
Ece Nur Degirmentepe, Sule Gungor, Emek Kocaturk, Utkan Kiziltac, Mine Adas, Selver Ozekinci, Amor Khachemoune
Acromegaly is a systemic syndrome caused by overproduction of growth hormone. Cutaneous, endocrine, cardiovascular, skeletal, and respiratory systems are affected. Cutaneous changes in acromegaly relate to overexpression of growth hormone and insulin-like growth factor 1 on skin cells and adnexa. Dermal glycosaminoglycan accumulation and edema cause skin distention that is most prominent in the face, hands, and feet. Oily skin with large pores, hypertrichosis, and excessive sweating are common features. Pigmented skin tags, acanthosis nigricans, and psoriasis are also encountered...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29466426/archaeological-and-anthropological-studies-on-the-harappan-cemetery-of-rakhigarhi-india
#13
Vasant S Shinde, Yong Jun Kim, Eun Jin Woo, Nilesh Jadhav, Pranjali Waghmare, Yogesh Yadav, Avradeep Munshi, Malavika Chatterjee, Amrithavalli Panyam, Jong Ha Hong, Chang Seok Oh, Dong Hoon Shin
An insufficient number of archaeological surveys has been carried out to date on Harappan Civilization cemeteries. One case in point is the necropolis at Rakhigarhi site (Haryana, India), one of the largest cities of the Harappan Civilization, where most burials within the cemetery remained uninvestigated. Over the course of the past three seasons (2013 to 2016), we therefore conducted excavations in an attempt to remedy this data shortfall. In brief, we found different kinds of graves co-existing within the Rakhigarhi cemetery in varying proportions...
2018: PloS One
https://www.readbyqxmd.com/read/29425220/a-new-method-of-identifying-target-groups-for-pronatalist-policy-applied-to-australia
#14
Mengni Chen, Chris J Lloyd, Paul S F Yip
A country's total fertility rate (TFR) depends on many factors. Attributing changes in TFR to changes of policy is difficult, as they could easily be correlated with changes in the unmeasured drivers of TFR. A case in point is Australia where both pronatalist effort and TFR increased in lock step from 2001 to 2008 and then decreased. The global financial crisis or other unobserved confounders might explain both the reducing TFR and pronatalist incentives after 2008. Therefore, it is difficult to estimate causal effects of policy using econometric techniques...
2018: PloS One
https://www.readbyqxmd.com/read/29395547/spinning-hurting-still-afraid-living-life-spaces-with-type-i-chiari-malformation
#15
Gavin J Andrews
Human geography's varied engagement with the brain has involved considerations of the way people know and respond to their environments, and their place-based experiences with emotions, mental illnesses and disorders, intellectual disabilities and particular neurological conditions. This paper argues however that this scholarship could be augmented by, and existing expertise be directed towards, considering physical brain abnormalities and injuries. As a case in point it considers the spatial experience of living with Type 1 Chiari Malformation...
January 31, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29370840/identification-of-compound-heterozygous-variants-in-the-noncoding-rnu4atac-gene-in-a-chinese-family-with-two-successive-foetuses-with-severe-microcephaly
#16
Ye Wang, Xueli Wu, Liu Du, Ju Zheng, Songqing Deng, Xin Bi, Qiuyan Chen, Hongning Xie, Claude Férec, David N Cooper, Yanmin Luo, Qun Fang, Jian-Min Chen
BACKGROUND: Whole-exome sequencing (WES) over the last few years has been increasingly employed for clinical diagnosis. However, one caveat with its use is that it inevitably fails to detect disease-causative variants that occur within noncoding RNA genes. Our experience in identifying pathogenic variants in the noncoding RNU4ATAC gene, in a Chinese family where two successive foetuses had been affected by severe microcephaly, is a case in point. These foetuses exhibited remarkably similar phenotypes in terms of their microcephaly and brain abnormalities; however, the paucity of other characteristic phenotypic features had made a precise diagnosis impossible...
January 25, 2018: Human Genomics
https://www.readbyqxmd.com/read/29349880/beyond-the-realist-turn-a-socio-material-analysis-of-heart-failure-self-care
#17
Allan McDougall, Elizabeth Anne Kinsella, Mark Goldszmidt, Karen Harkness, Patricia Strachan, Lorelei Lingard
For patients living with chronic illnesses, self-care has been linked with positive outcomes such as decreased hospitalisation, longer lifespan, and improved quality of life. However, despite calls for more and better self-care interventions, behaviour change trials have repeatedly fallen short on demonstrating effectiveness. The literature on heart failure (HF) stands as a case in point, and a growing body of HF studies advocate realist approaches to self-care research and policymaking. We label this trend the 'realist turn' in HF self-care...
January 2018: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29340969/on-the-predictive-validity-of-various-corpus-based-frequency-norms-in-l2-english-lexical-processing
#18
Xiaocong Chen, Yanping Dong, Xiufen Yu
The predictive validity of various corpus-based frequency norms in first-language lexical processing has been intensively investigated in previous research, but less attention has been paid to this issue in second-language (L2) processing. To bridge the gap, in the present study we took English as a case in point and compared the predictive power of a large set of corpus-based frequency norms for the performance of an L2 English visual lexical decision task (LDT). Our results showed that, in general, the frequency norms from SUBTLEX-US and WorldLex-Blog tended to predict L2 performance better in reaction times, whereas the frequency norms from corpora with a mixture of written and spoken genres (CELEX, WorldLex-Blog, BNC, ANC, and COCA) tended to predict L2 accuracy better...
January 16, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29314187/the-trouble-with-public-health-hiv-aids-in-canada-as-a-case-in-point
#19
EDITORIAL
Udo Schuklenk
No abstract text is available yet for this article.
February 2018: Bioethics
https://www.readbyqxmd.com/read/29307754/physical-constraints-in-cell-fate-specification-a-case-in-point-microgravity-and-phenotypes-differentiation
#20
REVIEW
Maria Grazia Masiello, Roberto Verna, Alessandra Cucina, Mariano Bizzarri
Data obtained by studying mammalian cells in absence of gravity strongly support the notion that cell fate specification cannot be understood according to the current molecular model. A paradigmatic case in point is provided by studying cell populations growing in absence of gravity. When the physical constraint (gravity) is 'experimentally removed', cells spontaneously allocate into two morphologically different phenotypes. Such phenomenon is likely enacted by the intrinsic stochasticity, which, in turn, is successively 'canalized' by a specific gene regulatory network...
May 2018: Progress in Biophysics and Molecular Biology
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